Antiproliferative and antiviral activity of methanolic extracts from Sardinian Maltese Mushroom (Cynomorium coccineum L.).

abstract：:Using a bioactivity-guided fractionation procedure, five cembranolides, 11-epi-sinulariolide acetate (1), 11-dehydrosinulariolide (2), sinulariolide (3), dihydrosinularin (4), and 3,4:8,11-bisepoxy-7-acetoxycembra-15(17)-en-1,12-olide (5), along with two nucleosides, 2'-deoxyadenosine and thymidine, were isolated from...

journal_title：Natural product research

authors： Hsieh PW,Chang FR,McPhail AT,Lee KH,Wu YC

更新日期：2003-12-01 00:00:00

abstract：:One new indole alkaloid (1) and one new indole alkaloidal glycoside (2), together with nine known alkaloids (3-11), were isolated from the leaves of Evodia rutaecarpa. Their structures were determined on the basis of spectroscopic and chemical methods. Compound 4 exhibited potent activity against Pseudomonas aeruginos...

journal_title：Natural product research

authors： Xia X,Luo JG,Liu RH,Yang MH,Kong LY

更新日期：2016-10-01 00:00:00

abstract：:Edible flowers consumption has increased in recent years due to their rich content of healthy phytochemicals. The aim of this study was to analyse the chemical profile of Cucurbita pepo L. flowers, and to explore their antioxidant and hypoglycaemic properties. Moreover, in order to assess in vivo effects, biochemical ...

journal_title：Natural product research

authors： Morittu VM,Musco N,Mastellone V,Bonesi M,Britti D,Infascelli F,Loizzo MR,Tundis R,Sicari V,Tudisco R,Lombardi P

更新日期：2019-09-30 00:00:00

abstract：:Three new methylated flavonol glucosides: 3-methoxy-7-O-β-(6″-galloylgluco-pyranoside) quercetin (1), 3,4'-dimethoxy-7-O-β-(6″-galloyl-glucopyranoside) quercetin (2) and 3-methoxy-7-O-β-(6″-galloylgluco-pyranoside) kaempferol (3), in addition to six known flavonols, were isolated from the ethyl acetate extract of Fuma...

journal_title：Natural product research

authors： Laraoui H,Long C,Haba H,Benkhaled M

更新日期：2013-01-01 00:00:00

abstract：:This study was performed to investigate the effect of ethanol extract from Saururus chinensis (Lour.) Baill on liver function, plasma lipid composition and antioxidant system with high-fat diet for 4 weeks. Rats were divided into the following five groups; untreated control group (normal), treated with 0.5% SE (normal...

journal_title：Natural product research

authors： Yu MH,Im HG,Lee JW,Bo MH,Kim HJ,Kim SK,Chung SK,Lee IS

更新日期：2008-02-15 00:00:00

abstract：:Triterpene saponins in medicinal plants attract scientific attentions for their structural diversity and significant bioactivities. In this work, a high-performance liquid chromatography coupled to electrospray ionisation and quadrupole time-of-flight mass spectrometry (HPLC-ESI-QTOF-MS/MS) method is used to rapidly s...

journal_title：Natural product research

authors： Zhang EF,Ling Y,Yin Z,Zhang Q

更新日期：2018-04-01 00:00:00

abstract：:Salvia apiana (white sage, Lamiaceae family) plant is native to southern California and parts of Mexico. Some Native American tribes local to this region consider S. apiana to be sacred and burn the leaves as incense for purification ceremonies. The plant has been used to treat sore throats, coughs, chest colds, upper...

journal_title：Natural product research

authors： Srivedavyasasri R,Hayes T,Ross SA

更新日期：2017-09-01 00:00:00

abstract：:Besides the chemotaxonomic value, nowadays determination of biodiversity and chemical variability has a commercial impact. The exact identity of raw material and constituents of botanical products, such as food supplements or herbal remedies, is a very important argument, being the real prerequisite for quality contro...

journal_title：Natural product research

authors： Toniolo C,Nicoletti M,Maggi F,Venditti A

更新日期：2014-01-01 00:00:00

abstract：:A new eremophilane sesquiterpene, capnodiumone (1), along with five known eremophilane sesquiterpenes (2-6) and eight other compounds (7-14), have been isolated from a mangrove-associated fungus Capnodium sp. SZ-F22. The chemical structures were elucidated on the basis of extensive spectroscopic analysis. The broth ex...

journal_title：Natural product research

authors： He H,Ma Z,Wang Q,Liu Y,Xu H

更新日期：2016-07-01 00:00:00

abstract：:Five new α-pyrones, xylariaopyrones E-I (1-5), along with three known analogues (6-8) were isolated from the cultivation broth of the endophytic fungus Xylariales sp. (HM-1). The structures of the new compounds including their absolute configurations were elucidated by comprehensive spectroscopic methods and quantum E...

journal_title：Natural product research

authors： Yang WW,Lu LW,Zhang XQ,Bao SS,Cao F,Guo ZY,Deng ZS,Proksch P

更新日期：2020-09-30 00:00:00

abstract：:Two new compounds, myrubol (1) and 3-oxo-11α-hydroxyfriedelane (2), were isolated from the roots of Myrica rubra along with eight known compounds (3-10). Their structures were determined through (1)H-NMR and (13)C-NMR spectral data, including 2-D experiments (HMBC, HMQC, (1)H-(1)H COSY and NOESY) and high-resolution m...

journal_title：Natural product research

authors： Li G,Wang D,Xu S

更新日期：2011-01-01 00:00:00

abstract：:Sanguisorba officinalis L. is a traditional herbal plant that belongs to the genus Sanguisorba and the family Rosaceae. A new ursane-type triterpenoid, 3-oxo-urs-11, 13(18)-dien-19, 28-olide (1), two known ursane-type triterpenoids (3 - 4) and three known oleanane-type triterpenoids (2, 5 - 6) were isolated from the r...

journal_title：Natural product research

authors： Wang R,Sun J,Jin M,Jin L,Qi Y,Cao L,Zhou W,Li G

更新日期：2019-12-04 00:00:00

abstract：:This study is designed to examine the chemical composition of the essential oil obtained from Buddleja thyrsoides Lam leaves from south Brazil. Gas chromatography/mass spectrometry analysis resulted in the detection of 12 components, representing 91.4% of the total oil composition. Germacrene D (27.16%), 1,10-di-epi-C...

journal_title：Natural product research

authors： Mahlke JD,Boligon AA,Machado MM,Athayde ML

更新日期：2013-01-01 00:00:00

abstract：:A new highly oxygenated pseudoguaianolide, rudbeckolide (1), was isolated from Rudbeckia hirta L. flowers. The structure of this terpenoid lactone was established on the basis of extensive 1D and 2D NMR spectroscopic analyses. The compound exhibited strong 5-lipoxygenase inhibitory activity (84.9% inhibition at 10 μg/...

journal_title：Natural product research

authors： Michael BR,Gedara SR,Amer MM,Stevenson L,Ahmed AF

更新日期：2013-01-01 00:00:00

abstract：:A new diterpenoid glycoside, 14,15-dinor-labdan-13-one-8-O-alpha-L-arabinopyranoside (1), was isolated from Conyza blinii. The structure of this new arabinoside was elucidated on the basis of extensive NMR and HRMS spectroscopy. In addition, the presence of 3R-hydroxyoctadecanoic acid in C. blinii was reported for the...

journal_title：Natural product research

authors： Su Y,Chen L,Wang D,Chai X,Guo D

更新日期：2008-04-15 00:00:00

abstract：:Today's world is increasingly seeking ways to replace the synthetic drugs with the therapeutic power of natural products. This study was designed to investigate the protective effects of Foeniculum vulgare (FV) and Salvia officinalis (SO) waters infusions against carcinogen chemical trichloroacetic acid (TCA)-exposure...

journal_title：Natural product research

authors： Celik I,Isik I

更新日期：2008-01-10 00:00:00

abstract：:The present study was aimed to isolate active constituents from Blumea axillaris (Lam.) DC (Asteraceae) against phytopathogenic fungi. Bioactivity guided fractionation of the successive n-hexane, chloroform and methanol extract led to the isolation of the monoterpene ester (4 R,5S)-4-hydroxy-7-tigloyloxycarvotanaceton...

journal_title：Natural product research

authors： Sivanandhan S,Pathalam G,Antony S,Michael GP,Balakrishna K,Boovaragamurthy A,Shirota O,Alwahibi MS,El-Shikh MS,Ignacimuthu S

更新日期：2020-10-16 00:00:00

abstract：:A new 20-membered macrolide named as levantilide C was isolated from the Micromonospora strain FIM07-0019 recovered from shallow coastal waters near the island of Chiloe, Chile. The chemical structure of levantilide C was elucidated on the basis of one- and two-dimensional NMR analysis. Two known indole derivatives we...

journal_title：Natural product research

authors： Fei P,Chuan-Xi W,Yang X,Hong-Lei J,Lu-Jie C,Uribe P,Bull AT,Goodfellow M,Hong J,Yun-Yang L

更新日期：2013-08-01 00:00:00

abstract：:In this study, the efficiency of nanoporous aluminium wires as fibres for headspace solid-phase microextraction (HS-SPME) of volatile compounds from Lippia citriodora was investigated and compared with two anodised methods. The prepared fibres are durable with very good chemical and thermal stability which can be coup...

journal_title：Natural product research

authors： Nemati Kharajuo M,Piryaei M,Babashpour Asl M,Abolghasemi MM

更新日期：2017-02-01 00:00:00

abstract：:From the deep-sea-derived fungus Aspergillus candidus, one novel (1) and three known (2-4) p-terphenyl derivates were isolated. The structure of the new compound was established mainly on the basis of extensive analysis of 1D and 2D NMR data. All four isolates were tested for in vitro anti-food allergic and antitumor ...

journal_title：Natural product research

authors： Lin YK,Xie CL,Xing CP,Wang BQ,Tian XX,Xia JM,Jia LY,Pan YN,Yang XW

更新日期：2019-06-24 00:00:00

abstract：:Pseudomonas syringae pv. actinidiae (PSA) is the causal agent of bacterial canker of kiwifruit. It is very difficult to treat pandemic disease. The prolonged treatment with antibiotics, has resulted in failure and resistance and alternatives to conventional antimicrobial therapy are needed. The aim of our study was to...

journal_title：Natural product research

authors： Vavala E,Passariello C,Pepi F,Colone M,Garzoli S,Ragno R,Pirolli A,Stringaro A,Angiolella L

更新日期：2016-01-01 00:00:00

abstract：:The aim of this study is to estimate the nutritive values, metabolites of Hass and Reed Avocado cultivars and evaluate their antimicrobial and anticancer activities. Hass was rich in water soluble vitamins, iron and calcium while, Reed contains more fat soluble vitamins. Benzaldehyde and butyl phenol derivatives were ...

journal_title：Natural product research

authors： Younis IY,Hifnawy MS,El-Hawary SS,El Bishbishy MH,Elateek SY

更新日期：2020-09-11 00:00:00

abstract：:The optimisation of nutritional requirements for dopamine (DA) synthesis by calcium alginate-entrapped mutant variant of Aspergillus oryzae EMS-6 using submerged fermentation technique was investigated. A total of 13 strains were isolated from soil. Isolate I-2 was selected as a better producer of DA and improved by e...

journal_title：Natural product research

authors： Ali S,Nawaz W

更新日期：2017-02-01 00:00:00

abstract：:This work was carried out to study the effect of topical application of Andrographis paniculata on the rate of wound enclosure and its histological features. A wound was created in four groups of rat in posterior neck region. Blank placebo was applied topically to the wounds of Group 1. Groups 2 and 3 were dressed wit...

journal_title：Natural product research

authors： Al-Bayaty FH,Abdulla MA,Abu Hassan MI,Ali HM

更新日期：2012-01-01 00:00:00

abstract：:The chemical composition of the volatile concentrate prepared by supercritical CO(2) extraction of the needles of Pinus nigra Arnold ssp. laricio Poiret from Corsica was investigated using GC (RI), GC-MS and (13)C NMR spectroscopy. The major component was by far manoyl oxide (63%), a compound of potential interest for...

journal_title：Natural product research

authors： Duquesnoy E,Marongiu B,Castola V,Piras A,Porcedda S,Casanova J

更新日期：2007-07-20 00:00:00

abstract：:A new citromycetin analogue, ascomycotin A (1), together with eight known compounds, wortmannilactone E (2), orcinol (3), orsellinic acid (4), isosclerone (5), (3R,4S)-( - )-4-hydroxymellein (6), diorcinol (7), chaetocyclinone B (8) and 2,5-dimethoxy-3,6-di(p-methoxypheny1)-1,4-benzoquinone (9), was isolated from the ...

journal_title：Natural product research

authors： Tian YQ,Lin XP,Liu J,Kaliyaperumal K,Ai W,Ju ZR,Yang B,Wang J,Yang XW,Liu Y

更新日期：2015-01-01 00:00:00

abstract：:Aedes aegypti is a primary vector of dengue, a mosquito-borne viral disease infecting 50-100 million people every year. Here, we biosynthesised mosquitocidal silver nanoparticles (AgNP) using the aqueous leaf extract of Crotalaria verrucosa. The green synthesis of AgNP was studied by UV-vis spectroscopy, SEM, EDX and ...

journal_title：Natural product research

authors： Murugan K,Sanoopa CP,Madhiyazhagan P,Dinesh D,Subramaniam J,Panneerselvam C,Roni M,Suresh U,Nicoletti M,Alarfaj AA,Munusamy MA,Higuchi A,Kumar S,Perumalsamy H,Ahn YJ,Benelli G

更新日期：2016-01-01 00:00:00

abstract：:The cholesteryl ester transfer protein (CETP), inhibition of which assists in maintaining a high level of high-density lipoprotein cholesterol in the blood, is a target for anti-atherosclerosis treatments. Orange monascus pigment was produced by a Monascus species in a 5 L jar fermenter and various derivative compound...

journal_title：Natural product research

authors： Jang H,Choe D,Shin CS

更新日期：2014-01-01 00:00:00

abstract：:Cinobufagin was one of the important cardenolidal steroids and a major component of Chan'Su, a famous traditional Chinese medicine. The urinary metabolites of cinobufagin after single oral doses of 25 mg kg⁻¹ in rats were investigated. Eleven metabolites were isolated and purified by liquid-liquid extraction, open-col...

journal_title：Natural product research

authors： He X,Hu H,Wu Y,Zeng X

更新日期：2012-01-01 00:00:00

abstract：:Headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography (GC-FID) was explored to determine the fingerprinting characteristic of Zingiber zerumbet L. volatiles to differentiate between different ginger species. The effect of different fibers [polydimethylsiloxane (PDMS, 7 μm), polyacrylate (PA, ...

journal_title：Natural product research

authors： Bhavya ML,Ravi R,Madhava Naidu M

更新日期：2019-07-22 00:00:00