Abstract:
:From the deep-sea-derived fungus Aspergillus candidus, one novel (1) and three known (2-4) p-terphenyl derivates were isolated. The structure of the new compound was established mainly on the basis of extensive analysis of 1D and 2D NMR data. All four isolates were tested for in vitro anti-food allergic and antitumor bioactivities. Compounds 3 and 4 showed potent antiproliferative effect against four cancer cells of Hela, Eca-109, Bel-7402, and PANC-1 with IC50 values ranging from 5.5 μM to 9.4 μM.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Lin YK,Xie CL,Xing CP,Wang BQ,Tian XX,Xia JM,Jia LY,Pan YN,Yang XWdoi
10.1080/14786419.2019.1633651subject
Has Abstractpub_date
2019-06-24 00:00:00pages
1-5eissn
1478-6419issn
1478-6427pub_type
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