Abstract:
:Investigation on the leaves of Melicope bonwickii (F.Muell.) T.Hartley (Rutaceae) afforded a new 7-(2'-hydroxy-3'-chloroprenyloxy)-4-methoxyfuroquinoline (1) together with the known 7-(2',3'-epoxyprenyloxy)-4-methoxyfuroquinoline (2), evellerine (3) kokusaginine (4) and an amide aurantiamide acetate (5). Compounds 1 and 2 showed significant activity against cervical cell lines (Hela).
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Komala I,Rahmani M,Sukari MA,Mohd Ismail HB,Cheng Lian GE,Rahmat Adoi
10.1080/14786410500462983subject
Has Abstractpub_date
2006-04-01 00:00:00pages
355-60issue
4eissn
1478-6419issn
1478-6427pii
J581M8135W643113journal_volume
20pub_type
杂志文章abstract::Two new glycerol esters, (S)-2-hydroxy-3-(octanoyloxy)propyl tetracosanoate (1) and (S)-3-(((S)-11-acetoxy octadecanoyl)oxy)propane-1,2-diyl diacetate (2), and eight known compounds, docosanedioic acid (3), 2,5-dimethylnonadecane (4), lupeol (5), stigmasterol (6), β-sitosterol (7), heptadecanoic acid (8), hexanedioic ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1777117
更新日期:2020-06-12 00:00:00
abstract::Chemical investigation of the aerial parts of Uvaria rufa (Dunal) Blume collected from Vietnam yielded one new lignan glycoside, ufaside (1), along with six known compounds, oxoanolobine (2), ergosta-4,6,8(14),22-tetraen-3-one (3), catechin (4), epicatechin (5), daucosterol (6) and glutin-5-en-3-one (7). Their chemica...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.971790
更新日期:2015-02-01 00:00:00
abstract::New sesquiterpene glycoside, cyclodipeptide and piperidine derivative were isolated from Streptomyces sp. YIM 63342. On the basis of spectral data, their structures were determined as 3R, 5R, 6S, 7E, 9R-megastigman-7-en-3,5,6,9-tetrol-9-O-β-D-apiofuranosyl-(1→ 2)-β-D-glucopyranoside (1), cyclo (L-Pro-L-OMet) (2) and (...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.718776
更新日期:2013-01-01 00:00:00
abstract::Two new flavonoids, 3, 3', 4' -Trihydroxy- 6, 7, 8 -trimethoxy flavone (1) and 3-Hydroxy-6, 7, 8, 3', 4'-pentamethoxy flavone (2) have been isolated from the methanol extract of Blumea eriantha DC. The structures of these compounds were determined on the basis of spectroscopic techniques such as IR, MS, 1 D, and 2 D N...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1672063
更新日期:2019-10-03 00:00:00
abstract::Endophytic fungi represent ubiquitous microbial organisms able to live in the tissues of different plants around the world and represent a prolific source of bioactive metabolites. In the present study, the endophytic fungus Aspergillus calidoustus was isolated from the medicinal plant Acanthospermum australe (Asterac...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1022777
更新日期:2016-01-01 00:00:00
abstract::The chemical investigation of whole plants Euphorbia stracheyi Boiss from China led to the isolation of one new ent-kaurane diterpene, ent-Kaurane-16β,17,19-triol-3-one (1), along with three known ent-kaurane diterpenoids (2-4) as ent-Kaurane-3α,16β,17-triol (2),ent-16S,17-dihydroxy-kaurane-3-one (3) and ent-3S,16S,17...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1222385
更新日期:2017-01-01 00:00:00
abstract::Studies on the stem of Garcinia mangostana have led to the isolation of one new xanthone mangosharin (1) (2,6-dihydroxy-8-methoxy-5-(3-methylbut-2-enyl)-xanthone) and six other prenylated xanthones, alpha-mangostin (2), beta-mangostin (3), garcinone D (4), 1,6-dihydroxy-3,7-dimethoxy-2-(3-methylbut-2-enyl)-xanthone (5...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410500463114
更新日期:2006-10-01 00:00:00
abstract::From the aerial parts of Citharexylum spinosum L., one new iridoid glucoside, the 7-ss-O-acetate (1) of lamiide, along with four known iridoid glucosides, lamiide (2), lamiidoside (3), duranterectoside C (4), 8-epiloganin (5) and one known lignan glucoside (+)-lyonirenisol-3a-O-ss-D-glucopyranoside (6) were isolated. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410500056694
更新日期:2006-02-01 00:00:00
abstract::A new chalcone named as balanochalcone (1) together with eight known compounds, methyl caffeate (2), β-hydroxydihydrochalcone (3), methyl gallate (4), dimethyl-6,9,10-trihydroxybenzo[kl]xanthene-1,2-dicarboxylate (5), p-coumaric acid (6), quercetin (7), scopoletin (8) and pinoresinol (9) have been isolated from the et...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1359172
更新日期:2018-04-01 00:00:00
abstract::A flavanone has been isolated first time from the stem of Bauhinia variegata, and its structure was identified by colour reactions and spectral analysis. In a search for novel anticancer compounds from medicinal plants, the isolated flavanone was tested for cytotoxic activity against 57 human tumour lines, representin...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802553752
更新日期:2009-01-01 00:00:00
abstract::Epicatechin (EC) is the most effective compound in Euonymus alatus (Thunb.)Sieb, and possesses a series of benefits, including anti-inflammatory, antioxidant, antiobesity and anticancer effects. In this study, we investigated the protective effects of EC in Acetaminophen(N-acetyl-p-aminophenol, APAP)-induced acute liv...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1503261
更新日期:2020-03-01 00:00:00
abstract::A new denudatine-type C20-diterpenoid alkaloid, pubesine (1), along with seven known diterpenoid alkaloids, altaconitine (2), 14-benzoylaconine (3), spicatine A (4), 14-benzoylaconine-8-palmitate (5), 14-O-acetylsenbusine A (6), senbusine A (7) and 14-acetylneoline (8) were isolated from the whole plant of Aconitum so...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1198348
更新日期:2017-03-01 00:00:00
abstract::The optimisation of nutritional requirements for dopamine (DA) synthesis by calcium alginate-entrapped mutant variant of Aspergillus oryzae EMS-6 using submerged fermentation technique was investigated. A total of 13 strains were isolated from soil. Isolate I-2 was selected as a better producer of DA and improved by e...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1233408
更新日期:2017-02-01 00:00:00
abstract::From a biologically active fraction of extract from the fungus Fomitopsis pinicola, a new lanostane triterpene was isolated, 3alpha-acetyloxylanosta-8,24-diene-21-ol (1), along with two known triterpenic acids, (2) and (3). The structures of the compounds were elucidated based on their spectral properties. [structure:...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410500520251
更新日期:2007-05-01 00:00:00
abstract::Phytochemical investigations on Phyllanthus emblica have resulted in the isolation of the two new flavonoids, kaempferol-3-O-alpha-L-(6''-methyl)-rhamnopyranoside (1) and kaempferol-3-O-alpha-L-(6''-ethyl)-rhamnopyranoside (2). Their structures were determined on the basis of extensive spectroscopic studies including ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410601124664
更新日期:2007-07-20 00:00:00
abstract::This manuscript describes the antioxidant activity of essential oil of Cinnamon (Cinnamomum zeylanicum) bark extracted by supercritical fluid extraction (SCFE), hydro distillation and steam distillation. The cinnamon bark essential oil exhibited a wide range of total phenolic contents, total flavonoid contents, reduci...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.1002088
更新日期:2015-01-01 00:00:00
abstract::The structure of pregnane oligoglycosides, namely rocinine (1) and marsdinine (11), which have been isolated from the chloroform soluble extract of the dried stem of Marsdenia roylei, were elucidated using MS, (1)H NMR, (13)C NMR, (1)H-(1)H COSY, HSQC and TOCSY experiments as well as chemical degradation and derivatis...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410902940933
更新日期:2009-01-01 00:00:00
abstract::Three new methylated flavonol glucosides: 3-methoxy-7-O-β-(6″-galloylgluco-pyranoside) quercetin (1), 3,4'-dimethoxy-7-O-β-(6″-galloyl-glucopyranoside) quercetin (2) and 3-methoxy-7-O-β-(6″-galloylgluco-pyranoside) kaempferol (3), in addition to six known flavonols, were isolated from the ethyl acetate extract of Fuma...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.778848
更新日期:2013-01-01 00:00:00
abstract::This study was aimed at characterising the secondary metabolites responsible for antibacterial and antioxidant activities of Acalypha wilkesiana. Purification of the defatted methanol leaves extract was guided by the DPPH free radical scavenging assay as well as by evaluation of the antibacterial activity against four...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.983105
更新日期:2015-01-01 00:00:00
abstract::The antitumour activity of the hydroalcoholic extract of the leaf (PCL) and stem bark (PCB) of Prosopis cineraria (L.) in Swiss albino mice was evaluated against an Ehrlich ascites carcinoma (EAC) tumour model. The activity was assessed using survival time, peritoneal cells, haematological studies, lipid peroxidation,...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.536159
更新日期:2011-04-01 00:00:00
abstract::Accumulating evidences have shown the beneficial effects of natural products for Alzheimer's disease (AD) treatment. The present study was designed to investigate the neuroprotective effects of secondary metabolites of Galactomyces geotrichum (SMGG) on D-galactose induced AD mice. SMGG was extracted and its toxicologi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1753738
更新日期:2020-04-15 00:00:00
abstract::Fourteen N,N'-diaryl unsymmetrically substituted thioureas were synthesised and their cytotoxic (in vitro), phytotoxic (in vitro), acetylcholinesterase and butrylcholinesterase activities were determined. Thiourea 16 exhibited high, and 1 and 3 showed significant phytotoxic activity. Thioureas 1, 3, 4, 6 and 10 showed...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802223778
更新日期:2009-01-01 00:00:00
abstract::Essential oils from the leaves, twigs and barks of Bocageopsis pleiosperma Maas were obtained by using hydrodistillation and analysed by using gas chromatography coupled to mass spectrometry. Several compounds (51) were detected and identified, being β-bisabolene the main component in all aerial parts of the plant, wi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.996148
更新日期:2015-01-01 00:00:00
abstract::Six compounds were isolated from the stems and leaves of Arachis hypogaea, including a new norsesquiterpene, arahyside A (1), and five known compounds, 4-(2-methoxyethyl)benzene-1,2-diol (2), (1(R,S),2(R,S))-1-phenylpropane-1,2-diol (3), tachioside (4), 1,3-benzenediol (5), demethylmedicarpin (6). Extensive spectrosco...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1607860
更新日期:2020-11-01 00:00:00
abstract::Sanguisorba officinalis L. is a traditional herbal plant that belongs to the genus Sanguisorba and the family Rosaceae. A new ursane-type triterpenoid, 3-oxo-urs-11, 13(18)-dien-19, 28-olide (1), two known ursane-type triterpenoids (3 - 4) and three known oleanane-type triterpenoids (2, 5 - 6) were isolated from the r...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1693569
更新日期:2019-12-04 00:00:00
abstract::A new ent-kaurane diterpenoid, lophanthodin G (1) and one known abietanoid, 6alpha-hydroxyferruginol (2), were isolated from the leaves of Isodon lophanthoides var. geradianus. The structure of the new compound 1 was established using spectroscopic methods including extensive 1D and 2D NMR analysis. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701640619
更新日期:2008-01-01 00:00:00
abstract::Two new briarane-type diterpenoids, dollfusilin A (1) and dollfusilin B (2), along with five known briarane-type diterpenoids (3-7), were isolated from the gorgonian Ellisella dollfusi collected from the South China Sea. The structures of the two new compounds (1 and 2) were elucidated through a comprehensive analysis...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.827191
更新日期:2014-01-01 00:00:00
abstract::Bothrops jararacussu venom's (Bj2015) batch was biomonitored quarterly for one year to assess phospholipase A2 (PLA2) activity, immunogenicity, neurotoxicity, and myotoxicity. In silico models were applied to evaluate losses using decay model and recoveries by predictive trend analysis. Mice were immunized with Bj2015...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1446010
更新日期:2019-08-01 00:00:00
abstract::This study investigated the in vitro anticancer potential of phytochemical constituents isolated from the methanolic extract of Eriocephalus africanus. One flavanone (hesperidin) and two flavones (luteolin and apigenin) were isolated for the first time from the plant using column chromatography. Standard MTT assay was...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1744138
更新日期:2020-03-25 00:00:00
abstract::A novel isoindole alkaloid named oleraisoindole (1), together with six known compounds, 7'-ethoxy-trans-feruloyltyramine (2), N-trans-feruloyltyramine (3), N-trans-feruloyl-3-methoxytyramine (4), N-trans-p-coumaroyltyramine (5) aurantiamide (6) and ferulic acid methyl ester (7) were isolated from Portulaca oleracea L....
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1419226
更新日期:2018-10-01 00:00:00