Abstract:
:A flavanone has been isolated first time from the stem of Bauhinia variegata, and its structure was identified by colour reactions and spectral analysis. In a search for novel anticancer compounds from medicinal plants, the isolated flavanone was tested for cytotoxic activity against 57 human tumour lines, representing leukaemia, non-small cell lung, colon, central nervous system, melanoma, ovarian, renal, prostate and breast cancers. The results showed that the flavanone has cytotoxic activity against human tumour cell lines.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Rajkapoor B,Murugesh N,Rama Krishna Ddoi
10.1080/14786410802553752subject
Has Abstractpub_date
2009-01-01 00:00:00pages
1384-9issue
15eissn
1478-6419issn
1478-6427pii
915676747journal_volume
23pub_type
杂志文章abstract::The chemical composition of the solvent extracted fixed oil of black cumin (Nigella sativa L.) seeds was determined by capillary GC and GC/MS. Thirty-two fatty acids (99.9%) have been identified in the fixed oil. The major fatty acids were linoleic acid (50.2%), oleic acid (19.9%), margaric acid (10.3%), cis-11,14-eic...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410902940909
更新日期:2010-07-01 00:00:00
abstract::A novel oxime polyketide, maydisone (1), along with two known compounds, 7-hydroxy-2,5-dimethylchromone (2) and 2,5-dimethylbenzoic acid (3) were isolated from the cultures of Bipolaris maydis. Their structures were identified by the application of NMR and MS data analyses and comparison with previous reports. Compoun...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1765339
更新日期:2020-05-13 00:00:00
abstract::Known diketopiperazine WIN 64821 and its asymmetric stereoisomers (1-3) had been isolated from the culture broth of a marine gut fungus Aspergillus sp. DX4H. The planar and stereochemistry for new compounds were determined by a suite of techniques including mass, NMR and CD spectra together with Marfey's method. Their...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1363752
更新日期:2018-04-01 00:00:00
abstract::Essential oils hydrodistilled from the leaves and stem barks of Goniothalamus macrocalyx Ban., Goniothalamus albiflorus Ban. and Goniothalamus tamirensis Pierre ex Fin. & Gagnep. growing in Vietnam were analysed by gas chromatography (GC) and GC-coupled with mass spectrometry. α-Pinene (1.7-50.0%), β-pinene (tr-6.8%),...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.814051
更新日期:2013-01-01 00:00:00
abstract::Chemical investigation of Trogopterus faeces has led to the isolation of seven flavonoids. Their structures were elucidated by chemical and spectral analyses. In an anticoagulative assay, three kaempferol coumaroyl rhamnosides had significant antithrombin activity. This is the first report on the occurrence of flavono...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.482057
更新日期:2010-11-01 00:00:00
abstract::Cultivation of the marine-derived Aspergillus versicolor MCCC 3A00080 with the addition of a histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), significantly enhanced the diversity of secondary metabolites. From the culture treated, a new biphenyl derivative, named versiperol A (1), along with two ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1465423
更新日期:2019-04-01 00:00:00
abstract::A phytochemical investigation on Lagotis brevituba led to the isolation and characterisation of 11 phenolic compounds: p-hydroxy-benzoic acid 1, methyl 3,4-dihydroxybenzoate 2, vanillic acid 3, protocatechuic acid 4, caffeic acid 5, glucose ester of (E)-ferulic acid 6, p-coumaric acid 7, vanillin 8, diosmetin-7-O-β-d-...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1239090
更新日期:2017-02-01 00:00:00
abstract::Three new aconitine-type C19-diterpenoid alkaloids, taipeinines A-C (1-3), were isolated from the roots of Aconitum taipaicum. The chemical structures of these three compounds were established as (1α,6α,8α,14α,16α)-20-ethyl-8,14-dihydroxy-1,6,16-trimethoxy-4-(methoxymethyl)-aconitane (1), (1α,6α,8α,14α,16β)-20-ethyl-8...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.861832
更新日期:2014-01-01 00:00:00
abstract::Timosaponin AIII (TAIII) exhibits extensive pharmacological activities and has been reported as a potent antitumour agent for various human cancers. In the present study, a potential industrial process for producing TAIII that involves biotransformation directly in the crude extract liquid of rhizoma anemarrhenae (RA)...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1169416
更新日期:2016-10-01 00:00:00
abstract::The whole plant, Tricholepis chaetolepis, powder was investigated using proximate and fluorescence analysis along with determining the extractive values. Total phenolics, flavonoids and total protein contents of n-hexane, chloroform and methanolic extracts of the whole plant were also determined. The anti-diabetic act...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1490905
更新日期:2020-02-01 00:00:00
abstract::Phytochemical investigations on Phyllanthus emblica have resulted in the isolation of the two new flavonoids, kaempferol-3-O-alpha-L-(6''-methyl)-rhamnopyranoside (1) and kaempferol-3-O-alpha-L-(6''-ethyl)-rhamnopyranoside (2). Their structures were determined on the basis of extensive spectroscopic studies including ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410601124664
更新日期:2007-07-20 00:00:00
abstract::GC/FID and GC-MS analysis revealed germacrene D, bicyclogermacrene, α-cadinol and cubenol as major compounds from aril. Germacrene D, bicyclogermacrene, trans-caryophyllene and δ-elemene are major compounds in fruits. Germacrene D, spathulenol, trans-caryophyllene and caryophyllene oxide are major compounds in leaves....
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.987145
更新日期:2015-01-01 00:00:00
abstract::Supported by a growing increase of scientific research attesting the health properties of salvia species, we have decided to investigate nine Salvia namely Salvia sclarea, Salvia atropatana, Salvia sahendica, Salvia hydrangea, Salvia xanthocheila, Salvia macrosiphon, Salvia glutinosa, Salvia chloroleuca and Salvia cer...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.939086
更新日期:2014-01-01 00:00:00
abstract::The isolation from olive pulp of a diacylglycerol showing an oleic as well as an elenoic acid residue, the latter probably derived from a natural enzymatic oleuropein hydrolysis, is reported. The given structure is supported by 1H- and 13C-NMR data. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410410001686382
更新日期:2005-01-01 00:00:00
abstract::A new 1,4-phenanthraquinone was isolated from the roots of Menispermum dauricum. The structure was elucidated as 7-hydroxy-3,6-dimethoxy-1,4-phenanthraquinone on the basis of spectral evidence. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410310001620592
更新日期:2004-08-01 00:00:00
abstract::Studies were made to increase the yield of piperine extraction using Naviglio Extractor® solid-liquid dynamic extractor (SLDE) from fruits of Piper longum. The effects of ratio w/v were investigated and optimised for the best method. The maximum yield of piperine (317.7 mg/g) from P. longum fruits was obtained in SLDE...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1217209
更新日期:2017-01-01 00:00:00
abstract::The monoterpenoid fractions of three endemic Galium ssp. (Rubiaceae) from Sardinia Island were examined and compared with the iridoidic pattern yet known in Galium species. This comparison evidenced theirs endemic characters. In particular, in G.corsicum and in G. glaucophyllum loganic acid was isolated and identified...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701614135
更新日期:2008-05-10 00:00:00
abstract::Pigments synthesised by Chryseobacterium sp. kr6 growing on feather waste were extracted and characterised. The pigment extract was characterised by KOH test, UV-vis, CIELAB colour system, HPLC-DAD-MS, FTIR and its antioxidant capacity was evaluated. A positive bathochromic shift was observed when kr6 colonies or pigm...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1423304
更新日期:2019-06-01 00:00:00
abstract::The ethanolic extract of the leaves of Eriobotrya japonica exhibited inhibitory activity against phosphodiesterase-4D (PDE4D), which is a therapeutic target of inflammatory disease. Subsequent bioassay-guided fractionation led to the isolation of a new triterpene (1), together with seven known triterpenoids, methyl co...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1300796
更新日期:2017-12-01 00:00:00
abstract::The ethanol extract of the Ficus carica L. leaves was tested to show strong nematicidal activity against pine wood nematode (PWN), Bursaphelenchus xylophilus, causing 90.93% corrected mortality within 72 h at 1.0 mg/mL. From the ethyl acetate soluble fraction of the F. carica L. leaves extract, the main nematicidal co...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1094804
更新日期:2016-09-01 00:00:00
abstract::A new furanodihydrobenzoxanthone, artomandin (1), together with three other flavonoid derivatives, artoindonesianin C, artonol B, and artochamin A, as well as β-sitosterol were isolated from the stem bark of Artocarpus kemando. The structures of these compounds were determined on the basis of spectral evidence. All of...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.534471
更新日期:2011-06-01 00:00:00
abstract::Nine lupeol derivatives were synthesised and assayed in vitro for their antitumour activities against three human tumour cells lines, A549, LAC and HepG2. Of lupeol derivaties, six were new compounds, and five compounds against A549 cells, four compounds against HepG2 cells and three compounds against LAC cells were e...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1329729
更新日期:2018-01-01 00:00:00
abstract::In Brazilian folk medicine, Protium heptaphyllum is used to treat inflammatory conditions and to hasten wound repair. This paper aims to investigate the chemical composition and the in vitro antibacterial effects of the essential oils (EOs) obtained from P. heptaphyllum leaves and ripe and unripe fruits against a repr...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1536659
更新日期:2020-08-01 00:00:00
abstract::The antioxidant, nitric oxide (NO) scavenging and malondialdehyde (MDA) scavenging activities of different Zataria multiflora (ZM) chemotype essential oils (EOs) were investigated. The main components are: ZM1 (carvacrol, p-cymene), ZM2 (carvacrol, p-cymene), ZM3 (carvacrol, p-cymene), ZM4 (linalool), ZM5 (carvacrol, ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.631136
更新日期:2012-01-01 00:00:00
abstract::In this study, the anti-tumour-promoting and thermal-induced protein denaturation inhibitory activities of β-sitosterol (1) and lupeol (2), isolated from Diospyros lotus L., were explored. Compound 1 showed a marked concentration-dependent inhibition against 12-O-tetradecanoylphorbol-13-acetate (20 ng/32 pmol)-induced...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1046381
更新日期:2016-01-01 00:00:00
abstract::The cholesteryl ester transfer protein (CETP), inhibition of which assists in maintaining a high level of high-density lipoprotein cholesterol in the blood, is a target for anti-atherosclerosis treatments. Orange monascus pigment was produced by a Monascus species in a 5 L jar fermenter and various derivative compound...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.905561
更新日期:2014-01-01 00:00:00
abstract::Lycopus europaeus L. leaves water extract (LEL) was subjected to phytochemical analysis, and evaluated for its antibacterial and antioxidant effects. Antibacterial activity testing was performed on Staphylococcus aureus clinical strains from catheter-related and skin infections by broth microdilution test. LEL showed ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1010086
更新日期:2015-01-01 00:00:00
abstract::The Nigerian and South African varieties of Siphonochilus aethiopicus were examined for their phytochemical constituents. The ethyl acetate extract of the rhizomes of the South African variety yielded a novel diarylheptanoid, 2,3-diacetoxy-7-(3'',4''-dihydroxy-5''-methoxyphenyl)-1-(4'-hydroxy-3'-methoxyphenyl)-5-hepte...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1799358
更新日期:2020-07-27 00:00:00
abstract::Two new chromones, spororrminone A (1, (S)-5-hydroxy-2-methyl-4-oxo-2-((S)-5-oxotetrahydrofuran-2-yl)chroman-7-carboxylic acid) and 2-epi-spororrminone A (2, (R)-5-hydroxy-2-methyl-4-oxo-2-((S)-5-oxotetrahydrofuran-2-yl)chroman-7-carboxylic acid), were isolated from an EtOAc extract of an endolichenic fungal strain Sp...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1610758
更新日期:2020-11-01 00:00:00
abstract::Two new flavonoids, 8-hydroxyisoscoparin (1) and luteolin 7-O-glucoside 4''-sulfate (2), along with eight known flavonoids, including luteolin 7-O-glucoside 2''-sulfate, were isolated and identified from Washingtonia filifera. All compounds were characterized by (1)H-NMR, (13)C-NMR, CI-MS, FABMS and UV. The antioxidan...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/1478641500059276
更新日期:2006-01-01 00:00:00