Abstract:
:A novel oxime polyketide, maydisone (1), along with two known compounds, 7-hydroxy-2,5-dimethylchromone (2) and 2,5-dimethylbenzoic acid (3) were isolated from the cultures of Bipolaris maydis. Their structures were identified by the application of NMR and MS data analyses and comparison with previous reports. Compound 1 showed the most powerful inhibition of α-glucosidase, with an IC50 value of 68.30 ± 0.83 µM.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Tran TM,Nguyen VK,Duong TH,Tran TN,Nguyen NH,Devi AP,Chavasiri W,Dinh MH,Tran NM,Sichaem Jdoi
10.1080/14786419.2020.1765339subject
Has Abstractpub_date
2020-05-13 00:00:00pages
1-6eissn
1478-6419issn
1478-6427pub_type
杂志文章abstract::A flavanone has been isolated first time from the stem of Bauhinia variegata, and its structure was identified by colour reactions and spectral analysis. In a search for novel anticancer compounds from medicinal plants, the isolated flavanone was tested for cytotoxic activity against 57 human tumour lines, representin...
journal_title:Natural product research
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