Abstract:
:The ethanol extract of the Ficus carica L. leaves was tested to show strong nematicidal activity against pine wood nematode (PWN), Bursaphelenchus xylophilus, causing 90.93% corrected mortality within 72 h at 1.0 mg/mL. From the ethyl acetate soluble fraction of the F. carica L. leaves extract, the main nematicidal constituents were obtained by bioassay-guided isolation and identified as linear furocoumarins bergapten (1) and psoralen (2) by mass and NMR spectral data analysis. Bergapten and psoralen had significant nematicidal activity against PWN with the LC50 values of 97.08 aKSnd 115.03 μ g/mL within 72 h, respectively. The two furocoumarins could inhibit the activities of amylase, cellulase and acetylcholinesterase (AchE) from PWN. The morphologies of PWNs changed much after they were treated by bergapten and psoralen. The physiological effects of bergapten and psoralen on PWN might provide helpful clues to elucidate their nematicidal mechanisms.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Guo Q,Du G,He H,Xu H,Guo D,Li Rdoi
10.1080/14786419.2015.1094804subject
Has Abstractpub_date
2016-09-01 00:00:00pages
1969-73issue
17eissn
1478-6419issn
1478-6427journal_volume
30pub_type
杂志文章abstract::Bothrops jararacussu venom's (Bj2015) batch was biomonitored quarterly for one year to assess phospholipase A2 (PLA2) activity, immunogenicity, neurotoxicity, and myotoxicity. In silico models were applied to evaluate losses using decay model and recoveries by predictive trend analysis. Mice were immunized with Bj2015...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1446010
更新日期:2019-08-01 00:00:00
abstract::Armoracia rusticana (AR) was tested for antimicrobial and antioxidants power. The compound demonstrated to inhibit fish pathogens such as Vibrio anguillarum, V. harvey, V. alginolyticus, Aeromonas hydrophila, A. salmonicida, Photobacterium damselae subspecie piscicida, Tenacibaculum marinum and Pseudomonas anguillisep...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1517121
更新日期:2020-06-01 00:00:00
abstract::In this study, Moringa oleifera flower extract and a trypsin inhibitor (MoFTI) isolated from it were evaluated for anti-protozoal activity against Trypanosoma cruzi and cytotoxicity to mammalian cells. The presence of flavonoids was remarkable in the HPLC fingerprints of the extract at 254 and 360 nm. Amino acid seque...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1389932
更新日期:2018-12-01 00:00:00
abstract::In this investigation, the effect of Matricaria chamomilla extract on linear incisional wound healing was studied. Thirty male Wistar rats were subjected to a linear 3 cm incision made over the skin of the back. The animals were randomly divided into three experimental groups, as control, olive oil, and treatment. Con...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701654875
更新日期:2010-05-01 00:00:00
abstract::The brown seaweed, Sargassum linearifolium (Turner) C. Agardh, 1820 is commonly available along the south-east coast of India. Its compound fucosterol was isolated and confirmed through spectral characterisation and chemical transformation methods. The antiplasmodial effect of the isolated fucosterol was investigated ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1342081
更新日期:2018-06-01 00:00:00
abstract::Designing propolis products for external use involves determining the optimal form of propolis for the introduction into dermatological pharmaceuticals and cosmetic preparations. As a potent ingredient, propolis oil extract from raw material harvested in Lithuania was analysed. The rheological characteristics, content...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.529440
更新日期:2011-09-01 00:00:00
abstract::The objective of this study was to determine whether endophytic fungi, isolated from Kadsura angustifolia produce nigranoic acid and its highly oxygenated derivatives. From the 426 endophytic fungi screened, Trichoderma harzianum SWUKD3.1610 was detected to have a component with the same TLC R ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1486311
更新日期:2019-07-01 00:00:00
abstract::Two new compounds including a new 3-arylcoumarin liquiritcoumarin (1), and a new flavonoid glycoside crotoliquiritin (2), together with twelve known compounds (3-14) were isolated from the radix and rhizome of Glycyrrhiza uralensis. Their structures were elucidated on the basis of extensive spectroscopic data analyses...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1715398
更新日期:2020-01-30 00:00:00
abstract::One new sesqui-neolignan compound, namely, sesqui-illisimonan A (1), one new neolignan, illisimonan A (2), and one new phenylpropanoid compound, illisimoid A (3) were isolated from the fruits of Illicium simonsii Maxim. The structures and absolute configurations of these compounds were determined by extensive spectros...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1422179
更新日期:2018-10-01 00:00:00
abstract::The current study introduces a new idea of utilising several bio/chemoinformatics tools in comparing two bio-similar natural molecules viz. curcumin and bisdemethoxycurcumin (BDMC) in order to select a potential nose-to-brain remedy for Alzheimer disease. The comparison comprised several bio/chemo informatics tools. I...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1385017
更新日期:2018-12-01 00:00:00
abstract::Phytochemical investigations on Phyllanthus emblica have resulted in the isolation of the two new flavonoids, kaempferol-3-O-alpha-L-(6''-methyl)-rhamnopyranoside (1) and kaempferol-3-O-alpha-L-(6''-ethyl)-rhamnopyranoside (2). Their structures were determined on the basis of extensive spectroscopic studies including ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410601124664
更新日期:2007-07-20 00:00:00
abstract::The volatile components of Tuber liyuanum were determined by HS-SPME with GC-MS for the first time. The effects of different fibre coating, extraction time, extraction temperature and sample amount were studied to get optimal extraction conditions. The optimal conditions were SPME fibre of Carboxen/PDMS, extraction ti...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1253082
更新日期:2017-04-01 00:00:00
abstract::Edible flowers consumption has increased in recent years due to their rich content of healthy phytochemicals. The aim of this study was to analyse the chemical profile of Cucurbita pepo L. flowers, and to explore their antioxidant and hypoglycaemic properties. Moreover, in order to assess in vivo effects, biochemical ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1672067
更新日期:2019-09-30 00:00:00
abstract::These are the days when one would go online first seeking home remedies before seeing a doctor. Apple cider vinegar (ACV) is one such popular yet scientifically under-validated remedy. Our results prove the unequivocal antimicrobial activity of ACV to be true at full strength concentrations. However, the activity cann...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1413567
更新日期:2019-03-01 00:00:00
abstract::The phytochemical investigation of the stem bark of Tinospora cordifolia Miers (Menispermaceae) has afforded four new compounds, named tinosporafuranol, tinosporafurandiol, tinosporaclerodanol, and tinosporaclerodanoid, along with beta-sitosterol, and their stereostructures have been elucidated correspondingly as 4-se...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802435679
更新日期:2010-06-01 00:00:00
abstract::This study was carried out to investigate the biomedicinal potential of aqueous extract (1.25 and 2.5%) of three henna ecotypes (Shahdad, Roodbar and Bam) against Two types of Gram positive and negative bacteria, Staphylococcus aureus (ATCC 25923), Streptococcus agalactiae (ATCC 29933), Bacillus cereus (ATCC 14579), C...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1569006
更新日期:2020-12-01 00:00:00
abstract::Natural products represent a rich source of bioactive compounds that have been historically used to obtain substances with great medicinal potential. The skin of anuran amphibians is a rich source of compounds with a wide range of biological activity. Alzheimer's disease (AD) is a complex disease associated with all k...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1591396
更新日期:2019-03-31 00:00:00
abstract::4-Methoxybenzene-1-ONN-azoxyformamide (1), 4-methoxybenzene-1-azoformamide (2), 4-hydroxyben-zene-1-azoformamide (3) and 4-hydroxybenzene-1-ONN-azoxyformamide (4) were isolated from the fruiting bodies of Calvatia craniiformis and Lycoperdon hiemale, respectively. Compounds 1 and 4 showed radicle growth inhibitory act...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410600649596
更新日期:2006-05-10 00:00:00
abstract::Two new steroidal alkaloids, salonine-A [(20S)-20-(N,N-dimethylamino)-3beta-(tigloylamino)-5alpha-pregn-14-en-2beta,4beta-diol] (1), and salonine-B [(20S)-20-(N,N-dimethylamino)-3beta-methoxy-pregn-5,16-diene] (2), were isolated from the MeOH extract of Sarcococca saligna, along with a known base, alkaloid-C (3). Thei...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/1057563021000051086
更新日期:2003-08-01 00:00:00
abstract::The antibacterial activity of essential oil and methanolic extract of Teucrium polium was determined against Pseudomonas aeruginosa, Pantoea agglomerans, Brenneria nigrifluens, Rhizobium radiobacter, Rhizobium vitis, Streptomyces scabies, Ralstonia solanacearum, Xanthomonas campestris and Pectobacterium cartovorum by ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.1000320
更新日期:2015-01-01 00:00:00
abstract::A new denudatine-type C20-diterpenoid alkaloid, designated as sinchianine (1), together with eight known diterpenoid alkaloids, 12-acetyl-12-epi-napelline (2), 12-epi-napelline (3), neoline (4), talatisamine (5), 14-O-acetylsenbusine A (6) and benzoylaconine (7), songorine (8) and aconitine (9), were isolated from the...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1410814
更新日期:2018-10-01 00:00:00
abstract::The world's rainforests hold untold potential for drug discovery. Rainforest plants are thought to contain evolved defensive active metabolites of greater diversity compared to plants from temperate regions. In recent years, the interest and overall output from pharmaceutical companies on novel antibacterial agents ha...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.537274
更新日期:2011-11-01 00:00:00
abstract::A new triterpene, javablumine A (1) along with six known ones were isolated from the aerial parts of Sambucus javanica Blume. They were identified as 3β,23-dihydroxy-11α,12α-epoxy-urs-20(30)-en-28,13β-olide (1), ursolic acid (2), pomolic acid (3), oleanic acid (4), 2α-hydroxy-oleanolic acid (5), α-amyrin (6), and lupe...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1596092
更新日期:2020-10-01 00:00:00
abstract::The objective of this work was to produce and characterise nanoemulsions containing tucumã extract and to evaluate the performance of the nanostructure and the free compound regarding antitumor activity, cytotoxicity, and oxidative metabolism in NB4/APL cells. The nanoemulsions showed adequate physicochemical characte...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1862830
更新日期:2020-12-24 00:00:00
abstract::A phytochemical investigation on Lagotis brevituba led to the isolation and characterisation of 11 phenolic compounds: p-hydroxy-benzoic acid 1, methyl 3,4-dihydroxybenzoate 2, vanillic acid 3, protocatechuic acid 4, caffeic acid 5, glucose ester of (E)-ferulic acid 6, p-coumaric acid 7, vanillin 8, diosmetin-7-O-β-d-...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1239090
更新日期:2017-02-01 00:00:00
abstract::Teucrium marum and T. subspinosum have been extracted with different polarity solvents, each crude extract was analysed with (1)H-NMR to compare the overall metabolic component. The polar extracts showed antioxidant activity in vitro. Verbascoside and arabinosyl-verbascoside were isolated and identified. Their concent...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701571384
更新日期:2007-10-01 00:00:00
abstract::Chemical investigation of the stems of Epigunum griffithianum led to the isolation and identification of a new triterpenoid saponin (1) and two known compounds (epigynosides A (2) and B (3)). These structures were elucidated by means of spectroscopic analysis (1D and 2D NMR, MS, UV, IR) as well as comparison with the ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1512989
更新日期:2020-05-01 00:00:00
abstract::Our laboratories have been investigating biological effects of a sesquiterpenoid polygodial and its natural and synthetic analogues. Herein, we report the evaluation of these compounds against the three forms of Trypanosoma cruzi, amastigotes, trypomastigotes and epimastigotes. Although polygodial was found to be poor...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1597350
更新日期:2019-04-28 00:00:00
abstract::This study investigated the flavonoid constituents of a traditional Chinese medical plant Ziziphora clinopodioides Lam. by using ultra-performance liquid chromatography coupled with quadruple time-of-flight mass spectrometry and screened the active components in regulating autophagy.Normal rat kidney (NRK) cells trans...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1452002
更新日期:2019-09-01 00:00:00
abstract::Phytochemical investigation of chloroform extract from the leaves of the marine plant Posidonia oceanica (L.) Delile (Posidoniaceae), yielded posidozinol, a new methylated sesquiterpene along with β-sitosterol and four known fatty acids: palmitic, palmitoleic, oleic and linoleic acids. The structure elucidation has be...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.725401
更新日期:2013-01-01 00:00:00