Abstract:
:Two new chromones, spororrminone A (1, (S)-5-hydroxy-2-methyl-4-oxo-2-((S)-5-oxotetrahydrofuran-2-yl)chroman-7-carboxylic acid) and 2-epi-spororrminone A (2, (R)-5-hydroxy-2-methyl-4-oxo-2-((S)-5-oxotetrahydrofuran-2-yl)chroman-7-carboxylic acid), were isolated from an EtOAc extract of an endolichenic fungal strain Sporormiella irregularis (No. 71-11-4-1). The structures of these compounds were identified by spectroscopic analyses. The absolute configuration of 1 was established by single-crystal X-ray diffraction. Spororrminone A (1) and 2-epi-spororrminone A (2) represent the first examples of 2-(5-oxotetrahydrofuran-2-yl) chromones with 7-carboxylic group.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Huang MJ,Li YJ,Tang J,Chen GD,Hu D,Xu W,Guo LD,Yao XS,Gao Hdoi
10.1080/14786419.2019.1610758subject
Has Abstractpub_date
2020-11-01 00:00:00pages
3117-3124issue
21eissn
1478-6419issn
1478-6427journal_volume
34pub_type
杂志文章abstract::Colletia paradoxa (Spreng.) Esc. (Rhamnaceae, Colletieae) is a medicinal plant, threatened with extinction in Brazil, presenting great morphological variability. Our objective is to investigate the phytochemical components, antioxidant capacity and antimycobacterial activity of different morphotypes of C. paradoxa in ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1598987
更新日期:2019-04-16 00:00:00
abstract::A new phenolic glycoside, 6-O-(4'-hydroxy-3',5'-dimethoxybenzoyl)-d-glucopyranose (4), and nine known compounds (1-3 and 5-10) were isolated from Juglans mandshurica Maxim. Compound structures were elucidated by NMR, HR-ESI-MS and acid hydrolysis. Compounds 5 and 6 are reported from this genus for the first time. Amon...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.902946
更新日期:2014-01-01 00:00:00
abstract::The aerial portions of Cynara scolymus commonly have been eaten as vegetables or functional foods by the people lived in Mediterranean region. In preliminary antioxidant screening, the rhizome portions (CSR) of this species showed better potential than leaves ones. However, neither phytochemical nor pharmacology studi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1645664
更新日期:2019-07-30 00:00:00
abstract::A new rare lumazine peptide, penilumamide E (1), together with 13 known compounds (2-14) were isolated from the fungus Aspergillus terreus. Their structures were identified by spectroscopic techniques. The relative configuration of 1 was confirmed by single-crystal X-ray diffraction analysis. Compound 10 exhibited ant...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1101107
更新日期:2016-01-01 00:00:00
abstract::Our laboratories have been investigating biological effects of a sesquiterpenoid polygodial and its natural and synthetic analogues. Herein, we report the evaluation of these compounds against the three forms of Trypanosoma cruzi, amastigotes, trypomastigotes and epimastigotes. Although polygodial was found to be poor...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1597350
更新日期:2019-04-28 00:00:00
abstract::A 70% ethanol extract from the leaves of Rosa davurica showed significant antioxidant activity in both superoxide anion and 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical-scavenging assays. Phytochemical study of this extract resulted in the isolation of eight compounds, including a new flavonoid glycoside. The che...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.811408
更新日期:2013-01-01 00:00:00
abstract::A new γ-pyrone derivative, acrepyrone A (1), and three known sorbicillinoids, trichodimerol (2), dihydrotrichodimerol (3) and tetrahydrotrichodimerol (4) were isolated from an endophytic fungus, Acremonium citrinum SS-g13, harboured in the roots of the Chinese medicinal plant Fructus mori. Their structures were determ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1548462
更新日期:2020-04-01 00:00:00
abstract::Physalis angulata is an annual herb which has tremendous medicinal uses. The antioxidant activity of the whole plant extract of Physalis angulata was investigated using DPPH radical scavenging activity. Purified compounds were isolated using column chromatography method. Their structures were determined using various ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1844691
更新日期:2020-11-23 00:00:00
abstract::A series of isoquinoline alkaloids including tetrahydroprotoberberines, N-methyl tetrahydroprotoberberines and protoberberines were facile synthesised with protopines as the starting material. All compounds were evaluated for their antibacterial activities against four pathogenic bacteria Escherichia coli, Staphylocco...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.867344
更新日期:2014-01-01 00:00:00
abstract::The antioxidant, nitric oxide (NO) scavenging and malondialdehyde (MDA) scavenging activities of different Zataria multiflora (ZM) chemotype essential oils (EOs) were investigated. The main components are: ZM1 (carvacrol, p-cymene), ZM2 (carvacrol, p-cymene), ZM3 (carvacrol, p-cymene), ZM4 (linalool), ZM5 (carvacrol, ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.631136
更新日期:2012-01-01 00:00:00
abstract::A new germacrenolide (1) and fourteen known terpenoids (2-15) were isolated from the barks of Magnolia maudiae (Dunn) Figlar (Magnoliaceae). The structure of (7αH,11βH)-2α,8α-dihydroxy-4α,5β-epoxy-germacr-1(10)-en-6α,12-olide (1) was elucidated by physical and spectroscopic data analysis, including 1D, 2D NMR and HR-E...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1385012
更新日期:2018-07-01 00:00:00
abstract::Phytochemical investigation of the stem and root barks of Friesodielsia obovata Benth (Annonaceae) afforded new 3',5'-diformyl-2',4',6'-trihydroxychalcone and N-formyl-7-hydroxyglaucine together with five known compounds, 3',5'-dimethyl-2',4',6'-trihydroxychalcone, (-)-crotepoxide, demethoxymatteucinol, lawinal, and b...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701194310
更新日期:2007-09-01 00:00:00
abstract::Alkylglycerols (AKGs) are bioactive natural compounds that vary by alkyl chain length and degree of unsaturation, and their absolute configuration is 2S. Three AKGs (5l-5n) were synthesised in enantiomerically pure form, and were characterised for the first time together with 12 other known and naturally occurring AKG...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1686370
更新日期:2019-11-04 00:00:00
abstract::Michael reaction acceptors (MRAs) are a class of active compounds. There is a great prospect to screen STAT3 inhibitors from Eupatorium lindleyanum, furthermore, to discover lead compounds for anti-triple-negative breast cancer (TNBC). In this study, glutathione (GSH) was employed, and a UPLC-MS screening method was d...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1396596
更新日期:2019-02-01 00:00:00
abstract::Tectona grandis Linn (Teak), is locally known as Sagwan, belongs to Lamiaceae family. It is one of the most valuable timber in the world, due to its beautiful surface and its resistance to termite and fungal damage. The main active ingredient compounds that are responsible for these action are tectoquinone, lapachol a...
journal_title:Natural product research
pub_type: 杂志文章,评审
doi:10.1080/14786419.2018.1440217
更新日期:2019-08-01 00:00:00
abstract::Three new flavonol glycosides (1-3), hippophins K-M, were isolated from the seed residue of Hippophae rhamnoides subsp. sinensis. The chemical structures of these three new compounds were identified by 1D, 2D NMR, mass spectroscopy and high resolution electrospray ionization mass spectrometry spectroscopic data and by...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.830216
更新日期:2014-01-01 00:00:00
abstract::Cultivation of the marine-derived Aspergillus versicolor MCCC 3A00080 with the addition of a histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), significantly enhanced the diversity of secondary metabolites. From the culture treated, a new biphenyl derivative, named versiperol A (1), along with two ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1465423
更新日期:2019-04-01 00:00:00
abstract::The present study has been focused on the extraction of natural pigments from tomato industry waste. At first, different solvents and solvents mixture were compared to determine which one is the best for extracting carotenoids compounds from tomato by-products. A mixture of hexane and acetone gave the highest caroteno...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1226828
更新日期:2017-01-01 00:00:00
abstract::Two new iridoids namely valerialloside A and valerianoside A (1 and 2) along with five known compounds (3-7) were isolated from the roots of Valeriana jatamansi Jones. The structure of new compounds were determined using 1D and 2D NMR including 1H-1H COSY, HSQC, HMBC and NOESY spectroscopic techniques. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1858412
更新日期:2020-12-09 00:00:00
abstract::A new alkynol, platycodynol (1), identified as 2, 3, 9, 13, 14-pentahydroxy-4, 6-tetradecadiyne, along with six known compounds (2-7) were obtained from Platycodins folium for the first time. Their structures were elucidated with infrared (IR), ultraviolet (UV), 1D and 2D nuclear magnetic resonance (NMR) spectroscopic...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1712381
更新日期:2020-01-17 00:00:00
abstract::Botryodiplodia theobromae Pat. belongs to the endophytic fungi that live within the tissues of medicinal plants and produce bioactive natural products. The endophyte was isolated from the leaves of Dracaena draco L. The LC-MS-based metabolite fingerprinting of the ethyl acetate extract of B. theobromae with antibacter...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1012715
更新日期:2015-01-01 00:00:00
abstract::A new sesquiterpenoid glycoside, consisting of one vetispirane-type, dmetelisproside A (1), together with two known megastigmane sesquiterpenoids, citroside A (2) and staphylionoside D (3) were isolated from the leaves of Datura metel L. The structures were determined by analysis of their MS and NMR data as well as by...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1590715
更新日期:2019-03-28 00:00:00
abstract::A new malyngamide (1) was isolated along with seven known compounds (2-8) from the marine cyanobacterium Moorea producens collected in Hawaii. Compound 1 represented the first reported malyngamide with a hydroxy moiety at C-7 of the characteristic fatty acid portion of the compound. Compound 1 showed cytotoxicity agai...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1338282
更新日期:2018-01-01 00:00:00
abstract::Extracts from three Calophyllum species endemic to Sri Lanka were tested for antifungal and antioxidant activities. Of them, only the root methanol extract of Calophyllum thwaitesii showed activity, and the active extract on activity guided fractionation yielded four antifungal active and three inactive xanthones. Ant...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410600899118
更新日期:2009-01-01 00:00:00
abstract::An HPLC/DAD/ESI-MSn method was established to characterise flavonoids in the seeds of Sophora alopecuroides L. All the flavonoids exhibited abundant [M-H]- ions, which triggered data-dependent multistage mass spectrometry fragmentations. Characteristic UV spectra were used to confirm flavonoid subtypes. In total, 22 f...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.688052
更新日期:2013-03-01 00:00:00
abstract::Timosaponin AIII (TAIII) exhibits extensive pharmacological activities and has been reported as a potent antitumour agent for various human cancers. In the present study, a potential industrial process for producing TAIII that involves biotransformation directly in the crude extract liquid of rhizoma anemarrhenae (RA)...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1169416
更新日期:2016-10-01 00:00:00
abstract::The chloroformic extract of the aerial parts of Ferula behboudiana (Umbelliferae) afforded four new polysulphane derivatives: 1-sec-butyl-2-[(E)-3-(methylthio)prop-1-enyl]disulphane (1), 1-sec-butyl-2-[(Z)-3-(methylthio)prop-1-enyl]disulphane (2), 1-[(E)-3-(methylthio)prop-1-enyl)-2-(1-(methylthio)propyl]disulphane (3...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410903458273
更新日期:2010-09-01 00:00:00
abstract::The brown seaweed, Sargassum linearifolium (Turner) C. Agardh, 1820 is commonly available along the south-east coast of India. Its compound fucosterol was isolated and confirmed through spectral characterisation and chemical transformation methods. The antiplasmodial effect of the isolated fucosterol was investigated ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1342081
更新日期:2018-06-01 00:00:00
abstract::A new cholestane-type steroidal glycoside, solamyriaside A (1), was isolated from the fruits of Solanum myriacanthum Dunal (Solanaceae), along with two known steroidal glycosides, namely, solaviaside A (2) and aculeatiside A (3), and three known steroidal alkaloid glycosides, namely, solamargine (4), khasianine (5) an...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1781117
更新日期:2020-06-19 00:00:00
abstract::A simple and efficient method was developed for simultaneous analysis of five illegal residual β2-agonists in cattle hair. β2-Agonists were quantified by ultra high performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry operating in positive multiple-reaction monitoring mode. T...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1190718
更新日期:2017-02-01 00:00:00