Spororrminone A and 2-epi-spororrminone A, two new chromones from an endolichenic fungus Sporormiella irregularis.

Abstract:

:Two new chromones, spororrminone A (1, (S)-5-hydroxy-2-methyl-4-oxo-2-((S)-5-oxotetrahydrofuran-2-yl)chroman-7-carboxylic acid) and 2-epi-spororrminone A (2, (R)-5-hydroxy-2-methyl-4-oxo-2-((S)-5-oxotetrahydrofuran-2-yl)chroman-7-carboxylic acid), were isolated from an EtOAc extract of an endolichenic fungal strain Sporormiella irregularis (No. 71-11-4-1). The structures of these compounds were identified by spectroscopic analyses. The absolute configuration of 1 was established by single-crystal X-ray diffraction. Spororrminone A (1) and 2-epi-spororrminone A (2) represent the first examples of 2-(5-oxotetrahydrofuran-2-yl) chromones with 7-carboxylic group.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Huang MJ,Li YJ,Tang J,Chen GD,Hu D,Xu W,Guo LD,Yao XS,Gao H

doi

10.1080/14786419.2019.1610758

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

3117-3124

issue

21

eissn

1478-6419

issn

1478-6427

journal_volume

34

pub_type

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