A new lumazine peptide penilumamide E from the fungus Aspergillus terreus.


:A new rare lumazine peptide, penilumamide E (1), together with 13 known compounds (2-14) were isolated from the fungus Aspergillus terreus. Their structures were identified by spectroscopic techniques. The relative configuration of 1 was confirmed by single-crystal X-ray diffraction analysis. Compound 10 exhibited antimalarial activity against Plasmodium falciparum with IC50 values of 2.83 μg/mL. Compounds 4 and 6 showed weak cytotoxicity against cholangiocarcinoma (CCA) cell lines. In addition, 4 and 11 exhibited weak cytotoxicity against human hepatoma cell line.


Nat Prod Res


Natural product research


Chaiyosang B,Kanokmedhakul K,Boonmak J,Youngme S,Kukongviriyapan V,Soytong K,Kanokmedhakul S




Has Abstract


2016-01-01 00:00:00












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    journal_title:Natural product research

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    authors: Torres-Tapia LW,Sosa-Espinosa T,Peraza-Sánchez SR

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    abstract::The chemical investigation of whole plants Piper terminaliflorum Tseng led to the isolation of one new furofuran lignan, 7-methoxyasarinin (1), along with three known amide alkaloids (2-4) as N-3,5-dimethoxy-4-hydroxycinnamoylpyrrole (2), dihydropipercide (3) and 1-[(2E,4E,9E)-10-(3,4-Methylenedioxyphenyl)-2,4,9-undec...

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    journal_title:Natural product research

    pub_type: 杂志文章


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    journal_title:Natural product research

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    authors: Manuguerra S,Caccamo L,Mancuso M,Arena R,Rappazzo AC,Genovese L,Santulli A,Messina CM,Maricchiolo G

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    pub_type: 杂志文章


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    pub_type: 杂志文章


    authors: Jiménez MEP,Pinilla CMB,Rodrigues E,Brandelli A

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    pub_type: 杂志文章


    authors: Ilavarasan R,Mohideen S,Venkataraman S

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    authors: Yu MH,Im HG,Lee JW,Bo MH,Kim HJ,Kim SK,Chung SK,Lee IS

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    journal_title:Natural product research

    pub_type: 杂志文章


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    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Atta-ur-Rahman,Feroz F,Zaheer-ul-Haq,Nawaz SA,Khan MR,Choudhary MI

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    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Singh S,Pandey VB,Singh TD

    更新日期:2012-01-01 00:00:00

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    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Feng X,Li DP,Zhang ZS,Chu ZY,Luan J

    更新日期:2014-01-01 00:00:00

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    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Sun J,Zhu ZX,Song YL,Ren Y,Dong D,Zheng J,Liu T,Zhao YF,Tu PF,Li J

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    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Yi M,Meng FC,Qu SY,Tao YY,Liao ZH,Chen M

    更新日期:2020-04-01 00:00:00

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    journal_title:Natural product research

    pub_type: 杂志文章


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    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Fang C,Gu D,Yang J,Li M,Liu H,Yang Y

    更新日期:2018-11-01 00:00:00

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    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Tran TM,Nguyen VK,Duong TH,Tran TN,Nguyen NH,Devi AP,Chavasiri W,Dinh MH,Tran NM,Sichaem J

    更新日期:2020-05-13 00:00:00

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    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Balas L,Hellal M,Rossi JC,Durand T

    更新日期:2005-06-01 00:00:00