Abstract:
:A new rare lumazine peptide, penilumamide E (1), together with 13 known compounds (2-14) were isolated from the fungus Aspergillus terreus. Their structures were identified by spectroscopic techniques. The relative configuration of 1 was confirmed by single-crystal X-ray diffraction analysis. Compound 10 exhibited antimalarial activity against Plasmodium falciparum with IC50 values of 2.83 μg/mL. Compounds 4 and 6 showed weak cytotoxicity against cholangiocarcinoma (CCA) cell lines. In addition, 4 and 11 exhibited weak cytotoxicity against human hepatoma cell line.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Chaiyosang B,Kanokmedhakul K,Boonmak J,Youngme S,Kukongviriyapan V,Soytong K,Kanokmedhakul Sdoi
10.1080/14786419.2015.1101107subject
Has Abstractpub_date
2016-01-01 00:00:00pages
1017-24issue
9eissn
1478-6419issn
1478-6427journal_volume
30pub_type
杂志文章abstract::In the course of our efforts to search new secondary metabolites from marine-derived fungi, one new hexylitaconic acid derivative, 3-(5-methoxycarbonylpentyl)-4-methylfuran-2,5-dione (1), and two dimeric analogues asperwelwinates A and B (2 and 3), together with ten known compounds, asperitaconic acid C (4), kotanin (...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1793152
更新日期:2020-07-15 00:00:00
abstract::Eight phenolic compounds, including two mixtures of two compounds, were isolated from the ethyl acetate extract of leaves and stems of Homalium brachybotrys. They were identified on the basis of spectroscopic data as quercetin-3-O-beta-glucopyranoside, luteolin-7-O-beta-glucopyranoside, 5,6-dihydro-6-beta-glucopyranos...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410601130679
更新日期:2007-11-01 00:00:00
abstract::The compositions of phenolic compounds in 10 cultivars of two mulberry species (Morus atropurpurea Roxb. and Morus alba Linn.) grown in four regions of China were analysed using HPLC-TOF-MS. Results showed that a total of 27 phenolic compounds were identified in these mulberry cultivars. The Taiwan cultivar from the J...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1274895
更新日期:2017-05-01 00:00:00
abstract::A new diterpenoid, 15-epi-(4E)-jatrogrossidentadione acetate, along with several known constituents has been isolated from the stem of Jatropha multifida. The structure of the new compound was settled by a detailed analysis of its 1D- and 2D-NMR spectra. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786411003792207
更新日期:2010-10-01 00:00:00
abstract::In order to identify genes related to Taxol biosynthesis, the mRNA differential display method was employed to compare mRNA populations from suspension cultured Taxus chinensis cells before and after beginning to produce Taxol. From a total display of about 4000 PCR products, 104 were derived from cells during the Tax...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410310001630573
更新日期:2004-08-01 00:00:00
abstract::This study was designed to investigate possible antidepressant-like effects of the extract prepared from the flowers of Hypericum montbretti Spach. (Guttiferae, Clusiaceae). Phytochemical constituents of the methanolic extract were analysed by HPLC method. The main flavonoid component was detected as rutin, and anothe...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.557800
更新日期:2011-09-01 00:00:00
abstract::The present study explored the schizonticidal potential of traditionally used Magnolia champaca (L.) Baill. ex. Pierre flowers, identifying constituents of interest. The extraction of phytoconstituents was carried out by microwave-assisted technique, isolated via column chromatography, and characterised by various phy...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1396595
更新日期:2019-02-01 00:00:00
abstract::The ethanolic extract of the stems of Viburnum fordiae Hance showed insecticidal and α-glucosidase inhibitory activities and then was fractionated by bioactivity-guided fractionation to obtain a rare C13-norisoprenoid (1), together with a new phenolic glycoside (2), and seven known compounds, alangionoside C (3), pisu...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1466130
更新日期:2019-09-01 00:00:00
abstract::A new dehydrodigallic acid derivative (1), along with 19 known compounds, including 6 phenolic derivatives, 2 steroids and 11 triterpenoids were isolated from the ethanol extract of the root of Geum urbanum. Herein, there is the first report of steroid and triterpene in Geum urbanum. The purified metabolites were char...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1425844
更新日期:2018-11-01 00:00:00
abstract::Naringin, as a component universal existing in the peel of some fruits or medicinal plants, was usually selected as the material to synthesise bioactive derivates since it was easy to gain with low cost. In present investigation, eight new acacetin-7-O-methyl ether Mannich base derivatives (1-8) were synthesised from ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1340280
更新日期:2018-03-01 00:00:00
abstract::A new β-tetralonyl glucoside, methylberchemiaside (1), along with five known compounds (2-6) were isolated from a fungus Colletotrichum sp . GDMU-1 derived from the leaves of Santalum album. Their structures were determined by detailed analysis of spectroscopic data. All compounds were tested for the inhibitory effect...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1452003
更新日期:2019-02-01 00:00:00
abstract::Analgesic and anti-inflammatory activities of the aqueous and ethanol extracts of Thespesia populnea Soland. ex. Correa (Malvaceae) leaves were evaluated in animal models. Orally-administered aqueous and ethanol extracts (100, 200 and 400 mg kg⁻¹ bw) showed significant analgesic activity in chemical-, mechanical- and ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.574134
更新日期:2012-01-01 00:00:00
abstract::The aerial parts of L. cultratus were submitted to a phytopharmacological investigation in order to isolate and identify the major secondary metabolites and evaluate its crude extract, fractions and isolated compounds for antiproliferative activity. Seven compounds were isolated and identified as the chalcones 2',4'-d...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1647427
更新日期:2019-08-12 00:00:00
abstract::A novel oxime polyketide, maydisone (1), along with two known compounds, 7-hydroxy-2,5-dimethylchromone (2) and 2,5-dimethylbenzoic acid (3) were isolated from the cultures of Bipolaris maydis. Their structures were identified by the application of NMR and MS data analyses and comparison with previous reports. Compoun...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1765339
更新日期:2020-05-13 00:00:00
abstract::Antioxidant, anticholinesterase and antidiabetic activities of three curcuminoids isolated from the Curcuma longa were simultaneously tested and compared in this study. The highest antioxidant power was detected for curcumin with the applied methods. The drug potentials of curcuminoids for Alzheimer's disease were con...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1299727
更新日期:2017-12-01 00:00:00
abstract::Physalis angulata is an annual herb which has tremendous medicinal uses. The antioxidant activity of the whole plant extract of Physalis angulata was investigated using DPPH radical scavenging activity. Purified compounds were isolated using column chromatography method. Their structures were determined using various ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1844691
更新日期:2020-11-23 00:00:00
abstract::Phytochemical investigation of the methylenechloride/methanol extract of the aerial parts of Stachys aegyptiaca afforded a new neoclerodane-type diterpene with a new side chain 1, in addition to two known diterpenes 2 and 3 and a known flavonoid glycoside 4. The structures of the compounds were determined by comprehen...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.830217
更新日期:2014-01-01 00:00:00
abstract::The anti-enteroviral activity of three stilbenoids isolated from the leaves of Macaranga barteri was investigated using the cytopathic effect reduction assay. The stilbenes were inactive against echovirus E13 but showed activity against echoviruses E7 and E19. In particular, vedelianin (2), schweinfurthin G (3) and ma...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1644505
更新日期:2019-07-25 00:00:00
abstract::Lavandin (Lavandula × intermedia Emeric ex Loiseleur) essential oils (EOs), from Abrial, Super and Grosso cultivars, cultivated and extracted in the South East of Spain, were analysed by using GC/MS to determine their composition, in both relative (peak area) and absolute (using standard curves) concentrations. Linalo...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1043632
更新日期:2016-01-01 00:00:00
abstract::Cinobufagin (CBF) is an active ingredient isolated from Venenum Bufonis extracted and dried from the secretory glands of Bufo gargarizans Cantor. The purpose of the study was to investigate the effects and underlying mechanisms of CBF on human breast cancer MCF-7 cells in vitro. Our results showed that CBF exhibited o...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1315575
更新日期:2018-02-01 00:00:00
abstract::A novel aromatic compound, grandiuvarone B (5-acetoxy-3-benzoyloxymethyl-5H-oxepin-4-one), along with a known compound grandiuvarone A (5-acetoxy-6-benzoyloxymethyl-5H-oxepin-4-one) were isolated from methanol extracts of Desmos chinensis leaves. Their structures were determined by various spectroscopic techniques inc...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1550762
更新日期:2020-04-01 00:00:00
abstract::In this work, we report a rapid and convenient HPLC-UV-DAD method for the isolation of δ-T3 on semi-preparative scale from two different vitamin E rich processed, commercially available products obtained from the fruits of Elaeis guineensis Jacq. (oil palm) and from the seeds of Bixa orellana L. (achiote tree). Chroma...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1320793
更新日期:2018-05-01 00:00:00
abstract::Oxygen radical absorbance capacity (ORAC) is a widely used hydrogen atom transfer-based method which measures the antioxidant capacity of natural products. ORAC values of oleaster (Elaeagnus angustifolia L.), which was extracted with ethanol/acetone (7:3, v/v), ethanol/water (1:1, v/v) and methanol/water (1:1, v/v) in...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.913243
更新日期:2014-01-01 00:00:00
abstract::Glaucocalyxin A is a natural ent-Kaurane diterpenoid. It has been widely studied for some important biological activities like cytotoxicity and anti-tumour, anti-bacterial, anti-oxidative, anti-coagulative, anti-thrombotic, immune and anti-neuroinflammatory activities. The aim of the present article is to review the a...
journal_title:Natural product research
pub_type: 杂志文章,评审
doi:10.1080/14786419.2014.934235
更新日期:2014-01-01 00:00:00
abstract::Essential oils derived from six different phenophases, namely early vegetative stage, late vegetative stage, early flowering stage, full flowering stage (FFS), late flowering stage and seed shattering stage of Origanum vulgare L. grown in Kumaon region of Uttarakhand, India were investigated by GC and GC-MS. A total o...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.602017
更新日期:2012-01-01 00:00:00
abstract::Cochliomycin G (1), a new 14-membered resorcylic acid lactone, together with six known analogues (2-7), was isolated from the culture broth of a marine-derived fungus Cochliobolus lunatus. The planar structure of 1 was established by extensive NMR spectroscopy, and the absolute configuration was elucidated by the comb...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1633646
更新日期:2021-02-01 00:00:00
abstract::From analysis by gas chromatography/mass spectrometry (GC/MS), the presence of either 2,4,5-tribromo-1H-imidazole (1) or 3,4,5-tribromo-1H-pyrazole (2) was tentatively identified in lipophilic extracts from the egg masses of three muricid molluscs. Synthesis of these compounds, followed by comparison of the GC retenti...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/1478641031000620682
更新日期:2004-10-01 00:00:00
abstract::Two new xanthone derivatives, penixanthones A (1) and B (2), together with three known compounds, aspenicillide (3), 1,5-dihydroxy-3-methoxy-7-methyl-anthracene-9,10-dione (4) and 1,2-indandiol (5), were isolated from the ethyl acetate extract of a culture of the fungus Penicillium sp. SYFz-1, which was separated from...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1297442
更新日期:2017-10-01 00:00:00
abstract::A new furan derivative named 3-(5-oxo-2,5-dihydrofuran-3-yl) propanoic acid (1) was isolated for the first time. Its structure was elucidated by UV, IR, NMR, HR-ESI-MS and the single-crystal X-ray diffraction spectroscopic data. Meanwhile, the antifungal and antibacterial activities of compound 1 was tested, it exhibi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1501687
更新日期:2019-10-01 00:00:00
abstract::The whole plant, Tricholepis chaetolepis, powder was investigated using proximate and fluorescence analysis along with determining the extractive values. Total phenolics, flavonoids and total protein contents of n-hexane, chloroform and methanolic extracts of the whole plant were also determined. The anti-diabetic act...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1490905
更新日期:2020-02-01 00:00:00