Abstract:
:Colletia paradoxa (Spreng.) Esc. (Rhamnaceae, Colletieae) is a medicinal plant, threatened with extinction in Brazil, presenting great morphological variability. Our objective is to investigate the phytochemical components, antioxidant capacity and antimycobacterial activity of different morphotypes of C. paradoxa in different environments. For this, the crude extract of the leaves and branches of the individuals sampled was used. The elimination capacity of the free radicals was determined by the DPPH method, the antimycobacterial activity by the broth microdilution method and the phenolic content by the spectrophotometric method using the Folin-Ciocalteu reagent and by HPLC. The extracts of C. paradoxa and its morphotypes showed significant amounts of phenolic compounds, including quercetin, quercitrin and rutin, besides considerable antioxidant and antimycobacterial activity No connection was detected between the phytochemical composition and different morphotypes of C. paradoxa.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Bastos Záchia NR,Piana M,Dos Santos Siqueira F,da Silva Jesus R,Athayde ML,Essi L,de Campos MMAdoi
10.1080/14786419.2019.1598987subject
Has Abstractpub_date
2019-04-16 00:00:00pages
1-5eissn
1478-6419issn
1478-6427pub_type
杂志文章abstract::Eight steroids, including five withanolides (1-5) and three other ergostane-type steroids (6-8), were isolated from the aerial parts of the halophyte Datura stramonium L., which were collected from the Yellow River Delta in China. Their structures were elucidated on the basis of extensive spectroscopic methods, especi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.800981
更新日期:2013-01-01 00:00:00
abstract::The aerial portions of Cynara scolymus commonly have been eaten as vegetables or functional foods by the people lived in Mediterranean region. In preliminary antioxidant screening, the rhizome portions (CSR) of this species showed better potential than leaves ones. However, neither phytochemical nor pharmacology studi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1645664
更新日期:2019-07-30 00:00:00
abstract::Santolina insularis is a Sardinian endemism that is widely used in traditional medicine. The essential oil was obtained with a yield of 2.7% and is mainly characterized by β-phellandrene (22.6%), myrcene (11.4%) and artemisia ketone (7.6%). The oil significantly reduced NO production without affecting macrophages viab...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1774764
更新日期:2020-06-04 00:00:00
abstract::Phytochemical investigation of the twigs of Garcinia nobilis led to the isolation of a new xanthone, named l-hydroxy-2,5-dimethoxyxanthone (1), together with 15 known compounds (2-16). The structures of the new and known compounds were established by means of spectroscopic methods and by comparison with previously rep...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.903398
更新日期:2014-01-01 00:00:00
abstract::Chemical investigation of the aerial parts of Uvaria rufa (Dunal) Blume collected from Vietnam yielded one new lignan glycoside, ufaside (1), along with six known compounds, oxoanolobine (2), ergosta-4,6,8(14),22-tetraen-3-one (3), catechin (4), epicatechin (5), daucosterol (6) and glutin-5-en-3-one (7). Their chemica...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.971790
更新日期:2015-02-01 00:00:00
abstract::Phytochemical investigation of the extracts of the leaves of Siparuna thecaphora (Poepp. et Endl.) A. DC. (Siparunaceae) allowed the isolation of one monoterpene glycoside, named trans-thujane-1α,7-diol 1-O-β-D-glucopyranoside (1) along with rutin, quercetin 3-O-β-D-glucopyranoside and 3,4-dihydroxybenzaldehyde. Their...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.843179
更新日期:2014-01-01 00:00:00
abstract::Antioxidant, anticholinesterase and antidiabetic activities of three curcuminoids isolated from the Curcuma longa were simultaneously tested and compared in this study. The highest antioxidant power was detected for curcumin with the applied methods. The drug potentials of curcuminoids for Alzheimer's disease were con...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1299727
更新日期:2017-12-01 00:00:00
abstract::Three compounds, toosendanin (1), kulactone (2) and scopoletin (3), were isolated from either the root bark and/or the stem bark of Melia volkensii. Their structures were determined on the basis of spectroscopic data generated and by comparison with data from the literature. 1 and 2, isolated for the first time from M...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1101104
更新日期:2016-09-01 00:00:00
abstract::This work reports the results and the comparison concerning the chemical and biomolecular analyses and the antifungal activity of three wild Pistacia species (Anacardiaceae) from Sardinia. Volatile oils from leaves and twigs of Pistacia x saportae, Pistacia lentiscus and Pistacia terebinthus were characterised using G...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1378211
更新日期:2018-12-01 00:00:00
abstract::As part of our search for compounds with cytotoxicity from endophytes of traditional Chinese medicines, two novel nor-sesquiterpenoids (1-2) with a new skeleton containing a tetrahydrofuran moiety were isolated form a rice medium of Fusarium tricinctum, an endophytic fungus isolated from the root of Ligusticum chuanxi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1712385
更新日期:2020-01-24 00:00:00
abstract::A series of isoquinoline alkaloids including tetrahydroprotoberberines, N-methyl tetrahydroprotoberberines and protoberberines were facile synthesised with protopines as the starting material. All compounds were evaluated for their antibacterial activities against four pathogenic bacteria Escherichia coli, Staphylocco...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.867344
更新日期:2014-01-01 00:00:00
abstract::A series of new thiazolyl chalcones, 1-[2-amino-4-methyl-1,3-thiazol-5-yl]-3-aryl-prop-2-en-1-one were prepared by piperidine mediated Claisen-Schmidt condensation of thiazolyl ketone with aromatic aldehyde. These chalcones on cyclisation gave 2-amino-6-(2-amino-4-methyl-1,3-thiazol-5-yl)-4-aryl-4H-pyridine-3-carbonit...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.536161
更新日期:2012-01-01 00:00:00
abstract::Artemisia herba-alba is widely used in traditional medicines for the treatment of several diseases. From the aerial parts organic extract of A. herba-alba, two new compounds, 1,3,8-trihydroxyeudesm-4-en-7α,11βH-12,6α-olide (1) and 5-β-D-glucopyranosyloxy-7-methoxy-6H-benzopyran-2-one (2), respectively, togethe...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1647430
更新日期:2019-07-31 00:00:00
abstract::A new β-hydroxydihydrochalcone glycoside named ziganin (1) and a new acylated flavonol glycoside named isorhamnetin-3-O-α-L-(2″,3″-di-O-trans-coumaroyl)-rhamnopyranoside) (2), along with two known flavonoid glycosides, a β-hydroxydihydrochalcone glycoside, a hydroxybenzoic acid derivative, a trinorguaiane type sesquit...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1062006
更新日期:2016-01-01 00:00:00
abstract::Armoracia rusticana (AR) was tested for antimicrobial and antioxidants power. The compound demonstrated to inhibit fish pathogens such as Vibrio anguillarum, V. harvey, V. alginolyticus, Aeromonas hydrophila, A. salmonicida, Photobacterium damselae subspecie piscicida, Tenacibaculum marinum and Pseudomonas anguillisep...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1517121
更新日期:2020-06-01 00:00:00
abstract::The cytotoxicity of six ent-kaurene diterpenoids isolated from the leaves of Isodon japonica (Burm.f.) Hara var. galaucocalyx (maxin) Hara was evaluated against three human tumour HepG2, GLC-82 and HL-60 cell lines through SRB assay, and their DNA damage potential (against HepG2 cell line) was assessed by comet assay....
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802267734
更新日期:2011-09-01 00:00:00
abstract::Chemical investigation of the mycelial extract of a mixed culture of two marine alga-derived fungal strains of the genus Aspergillus has yielded one new cyclotripeptide, psychrophilin E (1), the recently reported oxepin-containing alkaloids, protuboxepin A (2) and oxepinamide E (3), together with three other polyketid...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.880911
更新日期:2014-01-01 00:00:00
abstract::Headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography (GC-FID) was explored to determine the fingerprinting characteristic of Zingiber zerumbet L. volatiles to differentiate between different ginger species. The effect of different fibers [polydimethylsiloxane (PDMS, 7 μm), polyacrylate (PA, ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1643863
更新日期:2019-07-22 00:00:00
abstract::A new oligostilbenoid, diptoindonesin C, has been isolated from the tree bark of Shorea pinanga Scheff., along with the two known oligostilbenoids gnetin H and hopeaphenol, and a known coumarin scopoletin. The new oligostilbenoid was moderately active against brine shrimps Artemia salina. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410600761235
更新日期:2009-01-01 00:00:00
abstract::Michael reaction acceptors (MRAs) are a class of active compounds. There is a great prospect to screen STAT3 inhibitors from Eupatorium lindleyanum, furthermore, to discover lead compounds for anti-triple-negative breast cancer (TNBC). In this study, glutathione (GSH) was employed, and a UPLC-MS screening method was d...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1396596
更新日期:2019-02-01 00:00:00
abstract::Lavandin (Lavandula × intermedia Emeric ex Loiseleur) essential oils (EOs), from Abrial, Super and Grosso cultivars, cultivated and extracted in the South East of Spain, were analysed by using GC/MS to determine their composition, in both relative (peak area) and absolute (using standard curves) concentrations. Linalo...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1043632
更新日期:2016-01-01 00:00:00
abstract::A new bisabolane-type sesquiterpenoid, turmerone Q (1), along with six known compounds (2-7), were isolated from the rhizomes of Curcuma longa L. The structural elucidation of the new compound was conducted using 1H NMR, 13C NMR, HSQC, HMBC and NOESY spectroscopic analyses. The absolute configuration of 1 was elucidat...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1354185
更新日期:2018-08-01 00:00:00
abstract::The aim of the present study was to evaluate the phenolic contents in capsule and root methanolic extracts of Euphorbia retusa followed by identification of phenolic on capsule extracts through high-performance liquid chromatography (HPLC- DAD) for the first time. Likewise, the antioxidant activity of both extracts wa...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1582040
更新日期:2020-12-01 00:00:00
abstract::Azadirachtin-A (Aza-A, figure 1) was subjected to a variety of synthetic transformations and the antifeedant activity and toxicity of the azadirachtin derivatives were assessed against second instar larvae Spodoptera litura on castor leaves in comparison with the crude material containing 9.14% Aza-A, as well as relat...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410512331330558
更新日期:2005-07-01 00:00:00
abstract::A new pentacyclic triterpenoid fatty acid ester, lupan-20-ol-3(β)-yl hexadecanoate (1), together with lupan-20-ol-3(β)-yl acetate (2), olean-18-en-3(β)-yl hexadecanoate (3), dotriacontanoic acid (4), stigmasterol (5), rubiadin (6), nonadecanoic acid (7), palmitic acid (8) and camptothecin (9) were isolated from the he...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1160232
更新日期:2016-10-01 00:00:00
abstract::The aerial parts of L. cultratus were submitted to a phytopharmacological investigation in order to isolate and identify the major secondary metabolites and evaluate its crude extract, fractions and isolated compounds for antiproliferative activity. Seven compounds were isolated and identified as the chalcones 2',4'-d...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1647427
更新日期:2019-08-12 00:00:00
abstract::From a biologically active fraction of extract from the fungus Fomitopsis pinicola, a new lanostane triterpene was isolated, 3alpha-acetyloxylanosta-8,24-diene-21-ol (1), along with two known triterpenic acids, (2) and (3). The structures of the compounds were elucidated based on their spectral properties. [structure:...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410500520251
更新日期:2007-05-01 00:00:00
abstract::In this study, the anti-tumour-promoting and thermal-induced protein denaturation inhibitory activities of β-sitosterol (1) and lupeol (2), isolated from Diospyros lotus L., were explored. Compound 1 showed a marked concentration-dependent inhibition against 12-O-tetradecanoylphorbol-13-acetate (20 ng/32 pmol)-induced...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1046381
更新日期:2016-01-01 00:00:00
abstract::Two new steroidal alkaloids, salonine-A [(20S)-20-(N,N-dimethylamino)-3beta-(tigloylamino)-5alpha-pregn-14-en-2beta,4beta-diol] (1), and salonine-B [(20S)-20-(N,N-dimethylamino)-3beta-methoxy-pregn-5,16-diene] (2), were isolated from the MeOH extract of Sarcococca saligna, along with a known base, alkaloid-C (3). Thei...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/1057563021000051086
更新日期:2003-08-01 00:00:00
abstract::A novel monoterpenoid indole alkaloid, melognine (1) possessing an unprecedented skeleton with a 6/6/5/5/6/6 hexatomic rearranged ring system was isolated from the stems of Melodinus fusiformis. The structure with absolute configuration of 1 was established by extensive spectroscopic analyses and quantum ECD calculati...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1682579
更新日期:2019-11-01 00:00:00