Hypepontine, a new quaternary alkaloid with antimicrobial properties.

abstract：:4-Methoxybenzene-1-ONN-azoxyformamide (1), 4-methoxybenzene-1-azoformamide (2), 4-hydroxyben-zene-1-azoformamide (3) and 4-hydroxybenzene-1-ONN-azoxyformamide (4) were isolated from the fruiting bodies of Calvatia craniiformis and Lycoperdon hiemale, respectively. Compounds 1 and 4 showed radicle growth inhibitory act...

journal_title：Natural product research

authors： Kamo T,Kashiwabara M,Tanaka K,Ando S,Shibata H,Hirota M

更新日期：2006-05-10 00:00:00

abstract：:The aqueous methanolic extracts of Melastoma malabathricum L. exhibited antibacterial activity when assayed against seven microorganisms by the agar diffusion method. Solvent fractionation afforded active chloroform and ethyl acetate fractions from the leaves and the flowers, respectively. A phytochemical study result...

journal_title：Natural product research

authors： Wong KC,Hag Ali DM,Boey PL

更新日期：2012-01-01 00:00:00

abstract：:The aim of this work was to provide information about kinetin effects on chemical volatile profile of Curcuma zedoaria (Christm.) Roscoe after several days of plant dormancy release. Rhizomes of C. zedoaria were immersed in four kinetin concentrations (0, 50, 100, 150 mg ml-1, n = 12 by each concentration) for 30 min....

journal_title：Natural product research

authors： Portella RO,Marques MOM,Ono EO,Silva PSSD,Fernandes AM,de Almeida LFR

更新日期：2020-02-21 00:00:00

abstract：:The anti-enteroviral activity of three stilbenoids isolated from the leaves of Macaranga barteri was investigated using the cytopathic effect reduction assay. The stilbenes were inactive against echovirus E13 but showed activity against echoviruses E7 and E19. In particular, vedelianin (2), schweinfurthin G (3) and ma...

journal_title：Natural product research

authors： Segun PA,Ogbole OO,Akinleye TE,Faleye TOC,Adeniji AJ

更新日期：2019-07-25 00:00:00

abstract：:The mechanism of inhibition of jack bean and Bacillus pasteurii ureases was investigated by triacontanyl palmitate (1) which is a long-chain fatty ester and has been isolated from Symplocos racemosa Roxb. Lineweaver-Burk, Dixon plots, and their secondary replots showed that 1 is a non-competitive inhibitor of these en...

journal_title：Natural product research

authors： Lodhi MA,Abbasi MA,Choudhary MI,Ahmad VU

更新日期：2007-07-10 00:00:00

abstract：:In this study the crude ethyl acetate extracts and fractions from red algae Gracilaria edulis were studied against fish pathogens. G. edulis was extracted with ethyl acetate, fractionated in silica gel coloum chromatography and gradient hexane-ethyl acetate. The extract and fractions were subjected for bioassay guided...

journal_title：Natural product research

authors： Kasanah N,Amelia W,Mukminin A,Triyanto,Isnansetyo A

更新日期：2019-11-01 00:00:00

abstract：:In this study, essential oil compositions of two Hypericum L. taxa (Hypericum triquetrifolium Turra. and Hypericum aviculariifolium Jaub. et Spach subsp. depilatum var. depilatum (Freyn et Bornm.) Robson) naturally grown in Turkey were determined using gas chromatography and gas chromatography-mass spectrometry system...

journal_title：Natural product research

authors： Yuce E,Bagci E

更新日期：2012-11-01 00:00:00

abstract：:Chemical investigation of the stems of Epigunum griffithianum led to the isolation and identification of a new triterpenoid saponin (1) and two known compounds (epigynosides A (2) and B (3)). These structures were elucidated by means of spectroscopic analysis (1D and 2D NMR, MS, UV, IR) as well as comparison with the ...

journal_title：Natural product research

authors： Wang Q,Li WY,Wang YD

更新日期：2020-05-01 00:00:00

abstract：:Protein kinase C (PKC) plays a key role in neurotransmission in the central nervous system, and targeting PKC domain is considered as a strategy to modulate the anaesthetic effects. In this study, we described a synthetic pipeline to perform high-throughput virtual screening against a large library of 3D structural na...

journal_title：Natural product research

authors： Zhao J,Zhou C

更新日期：2015-01-01 00:00:00

abstract：:Two new benzoic acid derivatives, named methyl(S)-3-hydroxy-4-(2- hydroxy -6-methylheptan-2-yl)benzoate (1) and 2-hydroxy-3-(6- hydroxy-6-methylhept-1-en-2-yl)benzoic acid (2), were isolated from the ethanol extract of an endophytic fungus Aspergillus versicolor derived from the medicinal plant Euphorbia royleana. The...

journal_title：Natural product research

authors： Ye Y,Chen Y,Hou Y,Yu H,Zhu L,Sun Y,Zhou M,Chen Y,Dong M

更新日期：2020-06-11 00:00:00

abstract：:Phytochemical investigation of the extracts of the leaves of Siparuna thecaphora (Poepp. et Endl.) A. DC. (Siparunaceae) allowed the isolation of one monoterpene glycoside, named trans-thujane-1α,7-diol 1-O-β-D-glucopyranoside (1) along with rutin, quercetin 3-O-β-D-glucopyranoside and 3,4-dihydroxybenzaldehyde. Their...

journal_title：Natural product research

authors： Vera Saltos MB,Naranjo Puente BF,Malafronte N,Braca A

更新日期：2014-01-01 00:00:00

abstract：:Cathepsin B (catB) is a cysteine protease involved in tumour progression and represents a potential therapeutic target in cancer. Among the 15 evaluated extracts from cerrado biome, Myrcia lingua Berg. (Myrtaceae) extract demonstrated to be a source of compounds with potential to inhibit catB. Using bioactivity-guided...

journal_title：Natural product research

authors： Ramalho SD,de Sousa LR,Burger MC,Lima MI,da Silva MF,Fernandes JB,Vieira PC

更新日期：2015-01-01 00:00:00

abstract：:Triterpene saponins in medicinal plants attract scientific attentions for their structural diversity and significant bioactivities. In this work, a high-performance liquid chromatography coupled to electrospray ionisation and quadrupole time-of-flight mass spectrometry (HPLC-ESI-QTOF-MS/MS) method is used to rapidly s...

journal_title：Natural product research

authors： Zhang EF,Ling Y,Yin Z,Zhang Q

更新日期：2018-04-01 00:00:00

abstract：:Teucrium marum and T. subspinosum have been extracted with different polarity solvents, each crude extract was analysed with (1)H-NMR to compare the overall metabolic component. The polar extracts showed antioxidant activity in vitro. Verbascoside and arabinosyl-verbascoside were isolated and identified. Their concent...

journal_title：Natural product research

authors： Poli F,Serrilli AM,Scartezzini P,Muzzoli M,Maxia A,Ballero M,Serafini M,Bianco A

更新日期：2007-10-01 00:00:00

abstract：:The essential oil composition of the aerial parts of Nepeta erecta Benth. (Family: Lamiaceae) from Uttarakhand, India was analysed by capillary gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). A total of 34 constituents were identified representing 94.6% of the oil composition. Oxygenated mono...

journal_title：Natural product research

authors： Bisht DS,Joshi SC,Padalia RC,Mathela CS

更新日期：2012-01-01 00:00:00

abstract：:Thirty semicarbazone and thiosemicarbazone derivatives (2a-w and 4a-g) from chalcones containing furan and thiophene ring were designed and synthesized. They were characterized by IR, 1H NMR, 13C NMR and HRMS. The crystal structure of compound 2r was characterized by single crystal X-ray diffraction. It crystallizes i...

journal_title：Natural product research

authors： Cheng W,Xiao T,Qian W,Lu T,Zhang T,Tang X

更新日期：2020-03-16 00:00:00

abstract：:A new cinnamolyglycoflavonoid 3-cinnamoyltribuloside (1), its precursor tribuloside and two known flavonoid glycosides afzelin and astilbin were isolated from Heritiera littoralis Dryand (Sterculiaceae) ethanolic leaf extract. The dichloromethane leaf extract afforded two known pentacyclic triterpenoids, 3β-taraxerol ...

journal_title：Natural product research

authors： Christopher R,Nyandoro SS,Chacha M,de Koning CB

更新日期：2014-01-01 00:00:00

abstract：:Phytochemical investigation of chloroform extract from the leaves of the marine plant Posidonia oceanica (L.) Delile (Posidoniaceae), yielded posidozinol, a new methylated sesquiterpene along with β-sitosterol and four known fatty acids: palmitic, palmitoleic, oleic and linoleic acids. The structure elucidation has be...

journal_title：Natural product research

authors： Hammami S,Salem AB,Ashour ML,Cheriaa J,Graziano G,Mighri Z

更新日期：2013-01-01 00:00:00

abstract：:The essential oil of the 'resurrection plant' Myrothamnus moschatus (Baillon) Niedenzu endemic to Madagascar, where it is used in traditional medicine, was investigated for the first time for some biological activities. GC-FID and GC-MS analyses revealed trans-pinocarveol (35.6%), pinocarvone (20.0%), β-selinene (8.5%...

journal_title：Natural product research

authors： Nicoletti M,Maggi F,Papa F,Vittori S,Quassinti L,Bramucci M,Lupidi G,Petrelli D,Vitali LA,Ralaibia E,Rasoanaivo P

更新日期：2012-01-01 00:00:00

abstract：:Six new compounds, including three terpenoids (1-3) and three lignans (4-6), were isolated from the 95% EtOH extract of the twigs of Tripterygium hypoglaucum. Their structures were determined on the basis of extensive spectroscopic analysis. 9'-O-benzoyl-lariciresinol (4) showed weak cytotoxicity against HepG2/Adr cel...

journal_title：Natural product research

authors： Zheng H,Wang L,Yang T,Liu D,Li HM,Chen XQ,Li RT

更新日期：2020-07-01 00:00:00

abstract：:This study is designed to examine the chemical composition and antioxidant activity of the essential oil of Vitex megapotamica. Gas chromatography-mass spectrometry analysis resulted in the detection of 27 components, representing 92.36% of the total oil composition. The main components in the oil were butylated hydro...

journal_title：Natural product research

authors： de Brum TF,Boligon AA,Frohlich JK,Schwanz TG,Zadra M,Piana M,Froeder AL,Athayde ML

更新日期：2013-04-01 00:00:00

abstract：:The chemical investigation of the leaves and stem bark of Acacia polyacantha (Fabaceae) led to the isolation of a new oleanane-type triterpenoid saponin named polyacanthoside A 1 together with fifteen known compounds. Their structures were established from spectral , mainly HRESIMS, 1D NMR and 2D NMR and by comparison...

journal_title：Natural product research

authors： Fotso W G,Na-Iya J,Mbaveng T A,Ango Yves P,Demirtas I,Kuete V,Samuel Y,Ngameni B,Efferth T,Ngadjui T B

更新日期：2019-12-01 00:00:00

abstract：:In this study, the efficiency of nanoporous aluminium wires as fibres for headspace solid-phase microextraction (HS-SPME) of volatile compounds from Lippia citriodora was investigated and compared with two anodised methods. The prepared fibres are durable with very good chemical and thermal stability which can be coup...

journal_title：Natural product research

authors： Nemati Kharajuo M,Piryaei M,Babashpour Asl M,Abolghasemi MM

更新日期：2017-02-01 00:00:00

abstract：:Physalins are seco-steroids with a variety of pharmacological activities already described. In this study the pharmacological properties of a standardized concentrated ethanolic extract from Physalis angulata (CEEPA), rich in physalins B, D, F and G, were studied in models of pain and inflammation in mice. Inflammator...

journal_title：Natural product research

authors： do Espírito Santo RF,Lima MDS,Juiz PJL,Opretzka LCF,Nogueira RC,Ribeiro IM,Tomassini TCB,Soares MBP,Villarreal CF

更新日期：2019-12-24 00:00:00

abstract：:The microbial transformation of androst-4-ene-3,17-dione (4-AD; I) by three fungal species, involved Fusarium solani BH1031, Aspergillus awamori MH18 and Mucor circinelloides W12, has been studied. The latter two fungi were studied for the first time on biotransformation of 4-AD. The main product obtained by Fusarium ...

journal_title：Natural product research

authors： An X,Gao P,Zhao S,Zhu L,You X,Li C,Zhang Q,Shan L

更新日期：2021-02-01 00:00:00

abstract：:The methanolic extract of the aerial parts of Datura innoxia afforded a new withanolide, daturacin, the structure of which was elucidated as (20R, 22S)-21,24-epoxy-1,6-dioxo-14alpha-methoxy-5beta-witha-2,25(27)-dienolide (1) by an analysis of the spectroscopic data, including extensive NMR experiments. ...

journal_title：Natural product research

authors： Siddiqui BS,Arfeen S,Begum S,Sattar FA

更新日期：2005-09-01 00:00:00

abstract：:Cyanamide (NH(2)CN) has recently been isolated as a plant growth inhibitor from Vicia villosa, which is the first discovery of cyanamide from natural sources. To reveal the presence of the biosynthesized cyanamide in plants, 3.4 mM potassium ((15)N)nitrate was administered to 15- to 35-day-old plants of V. villosa, fr...

journal_title：Natural product research

authors： Kamo T,Kato K,Hiradate S,Nakajima E,Fujii Y,Hirota M

更新日期：2006-05-10 00:00:00

abstract：:In this investigation, the effect of Matricaria chamomilla extract on linear incisional wound healing was studied. Thirty male Wistar rats were subjected to a linear 3 cm incision made over the skin of the back. The animals were randomly divided into three experimental groups, as control, olive oil, and treatment. Con...

journal_title：Natural product research

authors： Jarrahi M,Vafaei AA,Taherian AA,Miladi H,Rashidi Pour A

更新日期：2010-05-01 00:00:00

abstract：:The hexane and ethanol extracts from Himatanthus bracteatus (Apocynaceae) stems were evaluated for antiviral activity against Zika virus, yellow fever virus and dengue virus 2 and for cytotoxicity in Vero cells by MTT assay. The ethanol extract showed good antiviral activity against the three viruses with selective in...

journal_title：Natural product research

authors： da Silva ML,Stehmann JR,Serafim MSM,Vale VV,Gontijo DC,Brandão GC,Kroon EG,de Oliveira AB

更新日期：2019-11-20 00:00:00

abstract：:The first chemotaxonomic study based on volatile components of Porella viridissima (Mitt.) Grolle is reported. The GC-MS analysis of ether extract was performed; ten santalane and five pinguisane-type sesquiterpenes were identified together with perrottetianal A as major diterpene. Most of detected santalane-type sesq...

journal_title：Natural product research

authors： Métoyer B,Lebouvier N,Hnawia E,Thouvenot L,Wang F,Harinantenaina Rakotondraibe L,Raharivelomanana P,Asakawa Y,Nour M

更新日期：2019-08-23 00:00:00