In vitro biological activities of the essential oil from the 'resurrection plant' Myrothamnus moschatus (Baillon) Niedenzu endemic to Madagascar.

Abstract:

:The essential oil of the 'resurrection plant' Myrothamnus moschatus (Baillon) Niedenzu endemic to Madagascar, where it is used in traditional medicine, was investigated for the first time for some biological activities. GC-FID and GC-MS analyses revealed trans-pinocarveol (35.6%), pinocarvone (20.0%), β-selinene (8.5%) and perillyl acetate (6.0%) as the major essential oil constituents. The oil strongly inhibited MDA-MB 231 (human breast adenocarcinoma) cells, with an IC(50) of 15 µg mL(-1), and the growth of Candida albicans, with an inhibition diameter of 18 mm, while its antioxidant activity, measured by DPPH and ABTS assay, proved to be negligible.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Nicoletti M,Maggi F,Papa F,Vittori S,Quassinti L,Bramucci M,Lupidi G,Petrelli D,Vitali LA,Ralaibia E,Rasoanaivo P

doi

10.1080/14786419.2012.665916

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

2291-300

issue

24

eissn

1478-6419

issn

1478-6427

journal_volume

26

pub_type

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