Synthesis and in vitro antitumour activities of lupeol derivatives.

abstract：:The antioxidant, nitric oxide (NO) scavenging and malondialdehyde (MDA) scavenging activities of different Zataria multiflora (ZM) chemotype essential oils (EOs) were investigated. The main components are: ZM1 (carvacrol, p-cymene), ZM2 (carvacrol, p-cymene), ZM3 (carvacrol, p-cymene), ZM4 (linalool), ZM5 (carvacrol, ...

journal_title：Natural product research

authors： Karimian P,Kavoosi G,Saharkhiz MJ

更新日期：2012-01-01 00:00:00

abstract：:Chemical investigation of the aerial parts of Uvaria rufa (Dunal) Blume collected from Vietnam yielded one new lignan glycoside, ufaside (1), along with six known compounds, oxoanolobine (2), ergosta-4,6,8(14),22-tetraen-3-one (3), catechin (4), epicatechin (5), daucosterol (6) and glutin-5-en-3-one (7). Their chemica...

journal_title：Natural product research

authors： Nguyen TH,Ho VD,Do TT,Bui HT,Phan VK,Sak K,Raal A

更新日期：2015-02-01 00:00:00

abstract：:Two new oleanane triterpenoid saponins, bodiniosides Q (1) and R (2), along with five known saponins, niga-ichigoside F1 (3), 3-O-[β-D-glucopyranosyl]-28-O-[α-L-rhamnopyranosyl -(1→2)-β-D-glucopyranosyl] arjunolic acid (4), asiaticoside E (5), sericoside (6), and bodinioside E (7), were isolated from the aerial parts ...

journal_title：Natural product research

authors： Yang L,Zhang L,Du J,Shao L,Yu F,Li R,Zhong J

更新日期：2020-02-06 00:00:00

abstract：:Machaerium, in the family Fabaceae, predominantly is a genus of a Neotropical distribution of trees, shrubs, and lianas occurring from southern Mexico to Brazil and northern Argentina and as far as South America. Several Machaerium species are widely used in traditional medicine and are considered to have multiple med...

journal_title：Natural product research

authors： Amen YM,Marzouk AM,Zaghloul MG,Afifi MS

更新日期：2015-01-01 00:00:00

abstract：:Two new, aramatosides A and B (1 and 2), together with seven known oleanane-type triterpene saponins (3-9) were isolated from the leaves of Aralia armata. Their structures were determined by combination of HR-ESI-MS, 1 D and 2 D NMR spectral data as well as comparison with the previous literature. Compounds 6-9 exhibi...

journal_title：Natural product research

authors： Yen PH,Chuong NTH,Lien GTK,Cuc NT,Nhiem NX,Thanh NTV,Tai BH,Seo Y,Namkung W,Park S,Kim SH,Minh CV,Kiem PV

更新日期：2020-05-22 00:00:00

abstract：:The chemical composition of the essential oils isolated from the aerial parts of Anthemis arvensis L. subsp. arvensis, Anthemis cretica subsp. messanensis (Brullo) Giardina & Raimondo and from flowers and leaves of Anthemis cretica subsp. columnae (Ten.) Frezén were determinated by GC-FID and GC-MS analyses. Torreyol ...

journal_title：Natural product research

authors： Riccobono L,Maggio A,Bruno M,Spadaro V,Raimondo FM

更新日期：2017-12-01 00:00:00

abstract：:The stem-derived essential oil of Aglaia odorata Lour. was obtained by hydrodistillation using a Clevenger-type system. Gas chromatography-mass spectrometry analysis of the oil revealed the identification of 39 compounds, representing 76.4% of the oil; germacrene D (20.3%), α-humulene (17.1%), α-himachalene (12.7%) an...

journal_title：Natural product research

authors： Joycharat N,Thammavong S,Voravuthikunchai SP,Plodpai P,Mitsuwan W,Limsuwan S,Subhadhirasakul S

更新日期：2014-01-01 00:00:00

abstract：:Alternanthera brasiliana is popularly known as 'penicillin' and used as an anti-inflammatory and for wound healing. The objective of this work was the phytochemical study of the species by analytical techniques such as LC-MS/MS and GC-MS. Twenty-seven compounds were identified, five by LC-MS and 22 by GC-MS analysis. ...

journal_title：Natural product research

authors： Alencar Filho JMT,Teixeira HAP,Sampaio PA,Pereira ECV,Amariz IAE,Rolim Neto PJ,Rolim LA,Araújo ECDC

更新日期：2020-02-01 00:00:00

abstract：:Members of the family Zygophyllaceae are distributed in arid areas of the world and are traditionally used against various health insults ranging from skin lesions to lethal cancer. Fagonia cretica Linn. is a plant having novel compounds responsive in diseases that are still considered as incurable or are curable with...

journal_title：Natural product research

authors： Qureshi H,Asif S,Ahmed H,Al-Kahtani HA,Hayat K

更新日期：2016-01-01 00:00:00

abstract：:The importance of the present study is to find out the phytochemical profile of essential oil (EO) of Artemisia tournefortiana Reichb. and its biological evaluation. Nineteen volatile constituents were identified from EO representing 93.47% of total oil composition. Oxygenated monoterpenes (54.46%) were found to be do...

journal_title：Natural product research

authors： Qadir M,Maurya AK,Agnihotri VK,Shah WA

更新日期：2021-01-01 00:00:00

abstract：:A sesquiterpenoid quinone, epi-ilimaquinone (1), and two sesquiterpene amino quinones, smenospongine (2) and glycinylilimaquinone (3), were isolated from the Fijian marine sponge Hippospongia sp. The structures of these compounds were determined by spectroscopic analysis. Compounds 1 and 3 were reported for the first ...

journal_title：Natural product research

authors： Kumar R,Subramani R,Aalbersberg W

更新日期：2013-01-01 00:00:00

abstract：:The aim of the study was comparing the chemical composition of the essential oils from five varieties of lavender (Lavandula angustifolia L.), and its biological activity against two pathogenic bacteria, Staphylococcus aureus and Pseudomonas aeruginosa. In the comparison we included the following varieties: 'Munstead'...

journal_title：Natural product research

authors： Adaszyńska M,Swarcewicz M,Dzięcioł M,Dobrowolska A

更新日期：2013-01-01 00:00:00

abstract：:The subfamily Asclepiadoideae (Apocynaceae) and the closely-related Periplocoideae are sources of many indigenous Indian medicinal plants. We surveyed antioxidant properties and total phenolic and flavonoid contents of 15 samples, representing 12 Indian medicinal plant species from these subfamilies. Total antioxidant...

journal_title：Natural product research

authors： Surveswaran S,Cai YZ,Xing J,Corke H,Sun M

更新日期：2010-02-01 00:00:00

abstract：:Chemical diversity is vital to antitubercular drug discovery as it ensures a novel bioactivity profile. Marine sponges have so far provided more than 1000 new bioactive molecules. Ethyl acetate extract of the marine sponge Dendrilla nigra on bioactivity-guided screening yielded three new compounds denigrins A-C, with ...

journal_title：Natural product research

authors： Murali Krishna Kumar M,Devilal Naik J,Satyavathi K,Ramana H,Raghuveer Varma P,Purna Nagasree K,Smitha D,Venkata Rao D

更新日期：2014-01-01 00:00:00

abstract：:The chemical investigation of the extract of the dried leaves of Rauvolfia caffra (Sond) (synonym Rauvolfia macrophylla) (Apocynaceae) led to isolation of a new glycoside derivative, rauvolfianine (1) as well as six known compounds: oleanolic acid (2), sitosterol-3-O-β-D-glucopyranoside (3), betulinic acid (4), vellos...

journal_title：Natural product research

authors： Ebeh Messanga R,Dominique Serge NB,Abouem A Zintchem A,Norbert MNI,Esther Del Florence MN,Patrick Hervé BD,Maximilienne Ascension N,Alex De Théodore A,Dieudonné Emmanuel P,Christian G B,Koert U

更新日期：2018-08-01 00:00:00

abstract：:Six compounds were isolated from the stems and leaves of Arachis hypogaea, including a new norsesquiterpene, arahyside A (1), and five known compounds, 4-(2-methoxyethyl)benzene-1,2-diol (2), (1(R,S),2(R,S))-1-phenylpropane-1,2-diol (3), tachioside (4), 1,3-benzenediol (5), demethylmedicarpin (6). Extensive spectrosco...

journal_title：Natural product research

authors： Jin WF,Luo ZH,Sun YP,Liu JS,Yu Y,Wang G,Wang GK

更新日期：2020-11-01 00:00:00

abstract：:Known diketopiperazine WIN 64821 and its asymmetric stereoisomers (1-3) had been isolated from the culture broth of a marine gut fungus Aspergillus sp. DX4H. The planar and stereochemistry for new compounds were determined by a suite of techniques including mass, NMR and CD spectra together with Marfey's method. Their...

journal_title：Natural product research

authors： Xu J,Hu Q,Ding W,Wang P,Di Y

更新日期：2018-04-01 00:00:00

abstract：:This study was carried out to investigate the biomedicinal potential of aqueous extract (1.25 and 2.5%) of three henna ecotypes (Shahdad, Roodbar and Bam) against Two types of Gram positive and negative bacteria, Staphylococcus aureus (ATCC 25923), Streptococcus agalactiae (ATCC 29933), Bacillus cereus (ATCC 14579), C...

journal_title：Natural product research

authors： Pasandi Pour A,Farahbakhsh H

更新日期：2020-12-01 00:00:00

abstract：:Three new neolignan derivatives (1-3), together with three known isolariciresinol derivatives (4-6) were isolated from Selaginella picta. Their structures were elucidated by spectroscopic methods (1D/2D NMR, HRESIMS and CD). All isolated compounds were assayed on the neuroprotective activity against the injury of HT-2...

journal_title：Natural product research

authors： Cheng F,Zou ZX,Xu PS,Zhang SH,Zhang Y,Yao CP,Xu KP,Tan GS

更新日期：2020-05-01 00:00:00

abstract：:A new chalcone named as balanochalcone (1) together with eight known compounds, methyl caffeate (2), β-hydroxydihydrochalcone (3), methyl gallate (4), dimethyl-6,9,10-trihydroxybenzo[kl]xanthene-1,2-dicarboxylate (5), p-coumaric acid (6), quercetin (7), scopoletin (8) and pinoresinol (9) have been isolated from the et...

journal_title：Natural product research

authors： Quang DN,So TC,Thanh NTP,Hoa LTP,Dien PH,Luong TM,Tung NQ,Long LD,Dai TD,Tien NQ

更新日期：2018-04-01 00:00:00

abstract：:One new iridoid glycoside, 6',10-di-O-(4-hydroxybenzoyl) aucubin (1), together with ten known compounds, including five diterpenoids (2-6), two triterpene glucosides (7-8) and three methoxylated flavonoids (9-11) were isolated from the fruits of Vitex rotundifolia. Compounds (3, 4, 7, and 8) were reported for the firs...

journal_title：Natural product research

authors： Zhao YY,Guo L,Cao LJ,Zhang J,Yin ZQ

更新日期：2017-11-01 00:00:00

abstract：:Aedes aegypti is a primary vector of dengue, a mosquito-borne viral disease infecting 50-100 million people every year. Here, we biosynthesised mosquitocidal silver nanoparticles (AgNP) using the aqueous leaf extract of Crotalaria verrucosa. The green synthesis of AgNP was studied by UV-vis spectroscopy, SEM, EDX and ...

journal_title：Natural product research

authors： Murugan K,Sanoopa CP,Madhiyazhagan P,Dinesh D,Subramaniam J,Panneerselvam C,Roni M,Suresh U,Nicoletti M,Alarfaj AA,Munusamy MA,Higuchi A,Kumar S,Perumalsamy H,Ahn YJ,Benelli G

更新日期：2016-01-01 00:00:00

abstract：:Four fractions were prepared from the crude extract of Caesalpinia minax Hance and the inhibitory activity of nitric oxide (NO) production release of RAW 264.7 cells stimulated by lipopolysaccharide (LPS) was evaluated. The ethyl acetate (EtOAc) fraction showed obvious inhibitory effect. Bioassay-guided fractionation ...

journal_title：Natural product research

authors： Liu Q,Bai B,Yang DP,Peng SY,Zhu LP,Luo MH,Zhao ZM

更新日期：2018-04-01 00:00:00

abstract：:Phytochemical investigation of the twigs of Garcinia nobilis led to the isolation of a new xanthone, named l-hydroxy-2,5-dimethoxyxanthone (1), together with 15 known compounds (2-16). The structures of the new and known compounds were established by means of spectroscopic methods and by comparison with previously rep...

journal_title：Natural product research

authors： Fouotsa H,Tatsimo SJ,Neumann B,Michalek C,Mbazoa CD,Nkengfack AE,Sewald N,Lannang AM

更新日期：2014-01-01 00:00:00

abstract：:A study on essential oil fractions of the Western Balkan endemic Sideritis romana L. subsp. purpurea (Tal. ex Benth.) Heywood collected in Montenegro is reported. The 24-h systematic steam distillation extraction procedure was performed. The gas chromatographic/mass spectrometric (GC/MS) analysis of the fractions show...

journal_title：Natural product research

authors： Garzoli S,Božović M,Baldisserotto A,Andreotti E,Pepi F,Tadić V,Manfredini S,Ragno R

更新日期：2018-05-01 00:00:00

abstract：:Since the last decades, socio-economic changes have a key role on eating habits affecting the nutritional status and health of people, in particular children and adolescents. The aim of this study was to compare the diet of student population both normal weight and overweight and obese in order to understand their eat...

journal_title：Natural product research

authors： Metro D,Tardugno R,Papa M,Bisignano C,Manasseri L,Calabrese G,Gervasi T,Dugo G,Cicero N

更新日期：2018-08-01 00:00:00

abstract：:Two Streptomyces spp. strains responsible for potato common scab infections in Uruguay which do not produce diketopiperazines were identified through whole-genome sequencing, and the virulence factor produced by one of them was isolated and characterized. Phylogenetic analysis showed that both pathogenic strains can b...

journal_title：Natural product research

authors： Lapaz MI,López A,Huguet-Tapia JC,Pérez-Baldassari MF,Iglesias C,Loria R,Moyna G,Pianzzola MJ

更新日期：2019-10-01 00:00:00

abstract：:The natural product lupeol 1 was isolated from aerial parts of Vernonia scorpioides with satisfactory yield, which made it viable to be used as starting material in semisynthetic approach. Ten lupeol derivatives 2-11 were prepared by classical procedures. Including, five new esters derivatives 7-11, which were obtaine...

journal_title：Natural product research

authors： Machado VR,Sandjo LP,Pinheiro GL,Moraes MH,Steindel M,Pizzolatti MG,Biavatti MW

更新日期：2018-02-01 00:00:00

abstract：:The present study explored the schizonticidal potential of traditionally used Magnolia champaca (L.) Baill. ex. Pierre flowers, identifying constituents of interest. The extraction of phytoconstituents was carried out by microwave-assisted technique, isolated via column chromatography, and characterised by various phy...

journal_title：Natural product research

authors： Mehrotra E,Vishwakarma J,Tripathi AC,Sonar PK,Saraf SK

更新日期：2019-02-01 00:00:00

abstract：:N-hexane and methanol extracts of Asystasia buettneri Lindau aerial parts exhibited antiproliferative activity on leukaemia blood carcinoma, K-562. Hexadecane (1), 1,3-propan-2-ol (9Z,12'Z,15″Z)-bis(doeicos-9,12,15-trienoate) (2), hydrocarbon, 2,3,3,10,23-pentamethyl tetraeicos-10,13,16-trien-1-ol (3), hexadecanoic ac...

journal_title：Natural product research

authors： Hamid AA,Aiyelaagbe OO,Negi AS,Luqman S,Kaneez F

更新日期：2018-09-01 00:00:00