Abstract:
:A new monoterpenoid indole alkaloid, 10-methoxyakuammidine (1), together with four known alkaloids (2-5), were isolated from the stems and leaves of Ochrosia elliptica. The structure of 1 was elucidated by extensive spectroscopic methods and the known compounds were identified by comparisons with data reported in the literature. New compound 1 was evaluated for its cytotoxicities against five human cancer cell lines: HL-60, SMMC-7721, A-549, MCF-7 and SW480 in vitro. 1 exhibited inhibitory effects with IC50 values comparable to those of cisplatin.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Chen AH,Liu QL,Ma YL,Jiang ZH,Tang JY,Liu YP,Chen GY,Fu YH,Xu Wdoi
10.1080/14786419.2016.1277349subject
Has Abstractpub_date
2017-07-01 00:00:00pages
1490-1494issue
13eissn
1478-6419issn
1478-6427journal_volume
31pub_type
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