Abstract:
:A new phenolic glycoside, 6-O-(4'-hydroxy-3',5'-dimethoxybenzoyl)-d-glucopyranose (4), and nine known compounds (1-3 and 5-10) were isolated from Juglans mandshurica Maxim. Compound structures were elucidated by NMR, HR-ESI-MS and acid hydrolysis. Compounds 5 and 6 are reported from this genus for the first time. Among compounds 1-10, only 1 exhibited cytotoxicity against MGC-803, A549, K562, JAR, HeLa, CaSKi and SiHa cell lines (IC50: 2.0, 5.3, 2.3, 6.9, 4.0, 6.6 and 2.7 μM, respectively).
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Yao D,Jin M,Zhang C,Luo J,Li R,Zheng M,Cui J,Li Gdoi
10.1080/14786419.2014.902946subject
Has Abstractpub_date
2014-01-01 00:00:00pages
998-1002issue
13eissn
1478-6419issn
1478-6427journal_volume
28pub_type
杂志文章abstract::A new germacrenolide (1) and fourteen known terpenoids (2-15) were isolated from the barks of Magnolia maudiae (Dunn) Figlar (Magnoliaceae). The structure of (7αH,11βH)-2α,8α-dihydroxy-4α,5β-epoxy-germacr-1(10)-en-6α,12-olide (1) was elucidated by physical and spectroscopic data analysis, including 1D, 2D NMR and HR-E...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1385012
更新日期:2018-07-01 00:00:00
abstract::The aim of this study is to estimate the nutritive values, metabolites of Hass and Reed Avocado cultivars and evaluate their antimicrobial and anticancer activities. Hass was rich in water soluble vitamins, iron and calcium while, Reed contains more fat soluble vitamins. Benzaldehyde and butyl phenol derivatives were ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1817013
更新日期:2020-09-11 00:00:00
abstract::Thirteen phenones were obtained from the 70% ethanol extract of Paeonia suffruticosa Andrews. Their structures were determined on the basis of chemical methods and spectral data. Among them, compound 1 was identified as a new compound, and compounds 5 and 13 were obtained from genus Paeonia for the first time. The inh...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1230114
更新日期:2017-02-01 00:00:00
abstract::Chromatographic fractionation of the chloroform extracts from the stem bark and stems of Guettarda grazielae resulted in the isolation of a new iridoid (guettardodiol, 1) and the secoiridoid sarracenin (2), described for the first time in this genus. The structural elucidation of these compounds was based on spectrosc...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.507547
更新日期:2011-10-01 00:00:00
abstract::The essential oil of Lippia microphylla (LM-OE) presents several pharmacological activities. This work evaluates the tocolytic effect of LM-OE on rats. LM-OE inhibited phasic contractions and relaxed tonic contractions on rat uterus. Considering that nitric oxide (NO) pathway regulates uterine contraction, LM-OE poten...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1614578
更新日期:2019-06-05 00:00:00
abstract::In this study, the anti-tumour-promoting and thermal-induced protein denaturation inhibitory activities of β-sitosterol (1) and lupeol (2), isolated from Diospyros lotus L., were explored. Compound 1 showed a marked concentration-dependent inhibition against 12-O-tetradecanoylphorbol-13-acetate (20 ng/32 pmol)-induced...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1046381
更新日期:2016-01-01 00:00:00
abstract::Pigments synthesised by Chryseobacterium sp. kr6 growing on feather waste were extracted and characterised. The pigment extract was characterised by KOH test, UV-vis, CIELAB colour system, HPLC-DAD-MS, FTIR and its antioxidant capacity was evaluated. A positive bathochromic shift was observed when kr6 colonies or pigm...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1423304
更新日期:2019-06-01 00:00:00
abstract::The search for bioactive compounds against diseases is imperative and the richness of the Amazon provides a large source to be explored. Current therapies for the treatment of parasitic infections have severe side effects and low efficacy, which makes the development of an effective chemotherapy extremely important. I...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1715395
更新日期:2020-01-25 00:00:00
abstract::The chemical composition of the essential oil (EO) obtained from the aerial parts of Rydingia michauxii (Briq.) Scheen & V.A. Albert was analysed by gas chromatography and gas chromatography/mass spectrometry (GC/MS). Eighty components were identified in the oil with caryophyllene oxide (20.1%), trans-verbenol (10.2%)...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1343321
更新日期:2018-01-01 00:00:00
abstract::Peperomia obtusifolia is a herbaceous perennial plant native to the Americas reported as a traditional medicine to treat snake bites and as a skin cleanser. The bioassay-guided fractionation of crude extracts from aerial parts of P. obtusifolia against a panel of clinically important fungi and bacteria, showed that he...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1628751
更新日期:2019-06-14 00:00:00
abstract::ABTRACT This study aims to design and synthesize a series of N-Acyl-N-(m-fluoro- benzyl)-6- amino-coumarins through the principle of active substructure stitching, which are based on the core structure of N-(m-fluoro-benzyl)-6-amino-coumarin. The structures of target compounds e1-e25 have been characterized by 1H NMR,...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1806268
更新日期:2020-08-13 00:00:00
abstract::Three flavonoid compounds were isolated from the roots of medicinal plant Tadehagi triquetrum (L.) H.Ohashi, also known as Desmodium triquetrum (Fabaceae). On the basis of the chemical and spectral analysis, the compounds were identified as baicalein (Flavone), naringin and neohesperidin (Flavonone). To the best of ou...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1561679
更新日期:2020-07-01 00:00:00
abstract::A new denudatine-type C20-diterpenoid alkaloid, designated as sinchianine (1), together with eight known diterpenoid alkaloids, 12-acetyl-12-epi-napelline (2), 12-epi-napelline (3), neoline (4), talatisamine (5), 14-O-acetylsenbusine A (6) and benzoylaconine (7), songorine (8) and aconitine (9), were isolated from the...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1410814
更新日期:2018-10-01 00:00:00
abstract::Platelet aggregation is fundamental to a wide range of physiological and pathological processes, including the induction of thrombosis and arteriosclerosis. Anti-platelet activity of a crude methanol extract and solvent fractions of Ashitaba roots (Angelica keiskei Koidz.) was evaluated using a turbidimetric method us...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.931389
更新日期:2014-01-01 00:00:00
abstract::A series of (E)-1-(4-alkyloxyphenyl)-3-(hydroxyphenyl)-prop-2-en-1-one have been successfully synthesised via Claisen-Schmidt condensation. The synthesised chalcone derivatives consisted of hydroxyl groups at either ortho, meta or para position and differed in the length of the alkyl groups, C (n) H(2) (n) (+1,) whe...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.502896
更新日期:2012-01-01 00:00:00
abstract::This study is designed to examine the chemical composition of the essential oil obtained from Buddleja thyrsoides Lam leaves from south Brazil. Gas chromatography/mass spectrometry analysis resulted in the detection of 12 components, representing 91.4% of the total oil composition. Germacrene D (27.16%), 1,10-di-epi-C...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.740035
更新日期:2013-01-01 00:00:00
abstract::A novel monoterpenoid indole alkaloid, melognine (1) possessing an unprecedented skeleton with a 6/6/5/5/6/6 hexatomic rearranged ring system was isolated from the stems of Melodinus fusiformis. The structure with absolute configuration of 1 was established by extensive spectroscopic analyses and quantum ECD calculati...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1682579
更新日期:2019-11-01 00:00:00
abstract::A new flavonoid, dihydroglychalcone-A, was isolated from the leaves extract of Glycosmis chlorosperma in addition to two known sulphur-containing amides, dambullin and gerambullin. The structure of the new compound was assigned as 2'-hydroxy-4,6'-dimethoxy-3',4'-(2",2"-dimethylpyrano)dihydrochalcone. The extract of th...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/1057563031000122121
更新日期:2004-02-01 00:00:00
abstract::A 70% ethanol extract from the leaves of Rosa davurica showed significant antioxidant activity in both superoxide anion and 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical-scavenging assays. Phytochemical study of this extract resulted in the isolation of eight compounds, including a new flavonoid glycoside. The che...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.811408
更新日期:2013-01-01 00:00:00
abstract::As part of our continuing efforts to explore bioactive compounds from natural resources, a new iridoid glycoside, adoxosidic acid-6'-oleuroperic ester (1), together with one known phenylethanoid glycoside (2) and two known flavonoid glycosides (3-4) were isolated from the fruit of Forsythia suspensa. The structure of ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1560288
更新日期:2020-05-01 00:00:00
abstract::Jatropha mutabilis (Pohl) Baill is an endemic species of the Caatinga biome, little studied in terms of chemical composition. The objective of this work was to develop an analytical methodology to quantify vitexin in the ethanolic extract of J. mutabilis and to evaluate the expectorant and antitussive activities in mi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1837807
更新日期:2020-10-30 00:00:00
abstract::The subfamily Asclepiadoideae (Apocynaceae) and the closely-related Periplocoideae are sources of many indigenous Indian medicinal plants. We surveyed antioxidant properties and total phenolic and flavonoid contents of 15 samples, representing 12 Indian medicinal plant species from these subfamilies. Total antioxidant...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802228827
更新日期:2010-02-01 00:00:00
abstract::In the course of our efforts to search new secondary metabolites from marine-derived fungi, one new hexylitaconic acid derivative, 3-(5-methoxycarbonylpentyl)-4-methylfuran-2,5-dione (1), and two dimeric analogues asperwelwinates A and B (2 and 3), together with ten known compounds, asperitaconic acid C (4), kotanin (...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1793152
更新日期:2020-07-15 00:00:00
abstract::The mechanism of inhibition of jack bean and Bacillus pasteurii ureases was investigated by triacontanyl palmitate (1) which is a long-chain fatty ester and has been isolated from Symplocos racemosa Roxb. Lineweaver-Burk, Dixon plots, and their secondary replots showed that 1 is a non-competitive inhibitor of these en...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410600906913
更新日期:2007-07-10 00:00:00
abstract::Acetylcholinesterase (AChE) inhibitors have been used for the symptomatic treatment of Alzheimer's disease. Eleven whole plants from Panama belonging to the Lycopodiaceae family have been screened for their anticholinesterase inhibitory and antioxidant activities by a thin-layer chromatography (TLC) bioautography meth...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.701217
更新日期:2013-03-01 00:00:00
abstract::Two new alkaloids 6-hydroxyethyldihydrochelerythrine (1) and 6-hydroxymethyl-7,8-demethylenedihydrochelerythrine (2) together with two analogues named maclekarpine E (3) and 6-hydroxymethyldihydrosanguinarine (4) were detected primarily from the leaves of Macleaya cordata by their characteristic mass spectrometry (MS)...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1285300
更新日期:2017-07-01 00:00:00
abstract::The search for bioactive natural products from the rhizomes of Paris polyphylla (Trilliaceae) has resulted in the isolation of four known constituents, 1,5-dihydroxy-7-methoxy-3-methylanthraquinone (1), diosgenin-3-O-[alpha-L-rhamnopyranosyl-(1 --> 3)-beta-D-glucopyranoside] (2), diosgenin-3-O-[alpha-L-rhamnopyranosyl...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701192777
更新日期:2007-04-01 00:00:00
abstract::Santolina insularis is a Sardinian endemism that is widely used in traditional medicine. The essential oil was obtained with a yield of 2.7% and is mainly characterized by β-phellandrene (22.6%), myrcene (11.4%) and artemisia ketone (7.6%). The oil significantly reduced NO production without affecting macrophages viab...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1774764
更新日期:2020-06-04 00:00:00
abstract::A new oleanane triterpenoid (2) was isolated from the roots of Rubia philippinensis. The structure of 2 was determined by analysis of HRMS and NMR data and identified as a rubiprasin analogue, 16β-hydroxyrubiprasin B. Four related known compounds were also encountered which include rubiprasin B (1), maslinic acid (3),...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1645656
更新日期:2019-07-25 00:00:00
abstract::Chemical investigation of the stems of Epigunum griffithianum led to the isolation and identification of a new triterpenoid saponin (1) and two known compounds (epigynosides A (2) and B (3)). These structures were elucidated by means of spectroscopic analysis (1D and 2D NMR, MS, UV, IR) as well as comparison with the ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1512989
更新日期:2020-05-01 00:00:00