Abstract:
:A new phthalide derivative, xylarphthalide A (1), along with two known compounds (-)-5-carboxylmellein (2) and (-)-5-methylmellein (3), were isolated from the endophytic fungus Xylaria sp. GDG-102 cultured from the Chinese medicinal plant Sophora tonkinensis. Their structures were identified by MS and NMR experiments, and the absolute configuration of 1 was further confirmed by single-crystal X-ray diffraction analysis. Compound 1-3 showed antibacterial activities against Bacillus megaterium, Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Shigella dysenteriae with MIC values of 12.5-25 μg/mL.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Zheng N,Yao F,Liang X,Liu Q,Xu W,Liang Y,Liu X,Li J,Yang Rdoi
10.1080/14786419.2017.1311892subject
Has Abstractpub_date
2018-04-01 00:00:00pages
755-760issue
7eissn
1478-6419issn
1478-6427journal_volume
32pub_type
杂志文章abstract::A new triterpenoid saponin, silenoviscoside F (1), was isolated from the roots of Silene viscidula, together with three known saponins, dianchinenoside D (2), sinocrassuloside I (3) and sinocrassuloside II (4). The structure of compound 1 was elucidated by spectroscopic data, GC-MS and chemical methods. The structures...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.637216
更新日期:2012-11-01 00:00:00
abstract::Alkaloids and phenolic compounds are among the most biologically active natural products from the Jacobaea/Senecio genera (Asteraceae). To isolate original natural products directly from Jacobaea gigantea crude polar extracts, centrifugal partition chromatography (CPC) was used. Previously, we reported the phytochemic...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1493584
更新日期:2019-08-01 00:00:00
abstract::Phebaclavin I, a novel 3-prenylated coumarin, was isolated from the aerial parts of Phebalium aff. tuberculosum (Rutaceae) together with five known related compounds, Phebaclavin A, B, D, G, H. The structure of phebaclavin I was established by spectroscopic methods. Several other known coumarins were obtained, includi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410500087525
更新日期:2006-03-01 00:00:00
abstract::Sahandinone (1), 12-deoxysalvipisone (2), miltirone (3), 7α-acetoxyroyleanone (4), and labda-7,14-dien-13-ol (5) were isolated from the roots of Salvia rhytidea Benth. (Lamiaceae). Their structures were elucidated by a combination of spectroscopic analyses including EIMS and NMR. The 13C NMR spectroscopic data were re...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1188096
更新日期:2017-02-01 00:00:00
abstract::A new cholestane-type steroidal glycoside, solamyriaside A (1), was isolated from the fruits of Solanum myriacanthum Dunal (Solanaceae), along with two known steroidal glycosides, namely, solaviaside A (2) and aculeatiside A (3), and three known steroidal alkaloid glycosides, namely, solamargine (4), khasianine (5) an...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1781117
更新日期:2020-06-19 00:00:00
abstract::Known diketopiperazine WIN 64821 and its asymmetric stereoisomers (1-3) had been isolated from the culture broth of a marine gut fungus Aspergillus sp. DX4H. The planar and stereochemistry for new compounds were determined by a suite of techniques including mass, NMR and CD spectra together with Marfey's method. Their...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1363752
更新日期:2018-04-01 00:00:00
abstract::Comparison of an authentic sample of altertenuol with altenuisol obtained by total synthesis and analysis of nuclear magnetic resonance spectra unambiguously revealed that altertenuol and altenuisol are identical compounds. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.819509
更新日期:2013-01-01 00:00:00
abstract::The latex of Ficus carica Linn. (Moraceae) has been shown to possess antiviral properties against some human viruses. To determine the ability of F. carica latex (F-latex) to interfere with the infection of caprine herpesvirus-1 (CpHV-1) in vitro, F-latex was resuspended in culture media containing 1% ethanol and was ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.918120
更新日期:2014-01-01 00:00:00
abstract::A series of new thiazolyl chalcones, 1-[2-amino-4-methyl-1,3-thiazol-5-yl]-3-aryl-prop-2-en-1-one were prepared by piperidine mediated Claisen-Schmidt condensation of thiazolyl ketone with aromatic aldehyde. These chalcones on cyclisation gave 2-amino-6-(2-amino-4-methyl-1,3-thiazol-5-yl)-4-aryl-4H-pyridine-3-carbonit...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.536161
更新日期:2012-01-01 00:00:00
abstract::The lipid peroxidation inhibitory activities of four hydroxyxanthones, isolated from the whole plant Swertia decussata, were evaluated for the first time. The most promising antioxidant among the xanthones, 1,7,8-trihydroxy-3-methoxyxanthone (swertianine, 4) was also tested for its scavenging potential against DPPH an...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410412331280032
更新日期:2005-06-01 00:00:00
abstract::The chemical investigation of whole plants Piper terminaliflorum Tseng led to the isolation of one new furofuran lignan, 7-methoxyasarinin (1), along with three known amide alkaloids (2-4) as N-3,5-dimethoxy-4-hydroxycinnamoylpyrrole (2), dihydropipercide (3) and 1-[(2E,4E,9E)-10-(3,4-Methylenedioxyphenyl)-2,4,9-undec...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1350671
更新日期:2018-02-01 00:00:00
abstract::Alzheimer's disease (AD) is a multifactorial health problem widespread over the world. Regarding the historical importance of the alkaloids in the central nervous system pharmacology they remain as promising drug candidates against AD. Seven alkaloids from Amaryllidaceae and Fabaceae were evaluated in vivo, in vitro a...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1727471
更新日期:2020-02-18 00:00:00
abstract::A new resin glycoside, named calysolin XVIII (1), was isolated from the leaves, stems and roots of Calystegia soldanella Roem. et Schult. (Convolvulaceae). The structure of 1 was defined as 11S-jalapinolic acid 11-O-β-d-glucopyranosyl-(1 → 3)-O-(2-O-2S-methylbutyryl,4-O-3-hydroxy-2-methylenebutyryl)-α-l-rhamnopyranosy...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1280492
更新日期:2017-11-01 00:00:00
abstract::Artemisia annua L. is an annual Eurasian desert-steppe plant. The composition of essential oils found in Artemisia annua from Russian (Buryatian) flora was analyzed in this work using gas chromatography mass-spectrometry method. Artemisia ketone, β-selinene, caryophyllene, caryophyllene oxide, germacrene D were the ma...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1548461
更新日期:2020-09-01 00:00:00
abstract::Three alkaloids, (3-chloro-2-hydroxypropyl) trimethylammonium chloride (1), p-(acetylamino)-phenol (2) and 4,4'-diacetamidodiphenyl ether (3), were isolated from Reineckia carnea herba. Their structures were determined by detailed analysis of their 1D and 2D NMR spectra and MS. Compounds 1 and 3 were new natural produ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.900618
更新日期:2014-01-01 00:00:00
abstract::The phytochemical constituents in the aqueous methanolic leaf extract of Triclisia gilletii responsible for its nephroprotective potentials against ethane-1,2-diol induced nephrolithiasis as previously investigated in our laboratory were elucidated. The extract was prepared using 80% aqueous methanol in 72 h, Phytoche...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1845672
更新日期:2020-11-12 00:00:00
abstract::Formulations of traditional medicines are usually made up of a complex mixture of herbs. However, effective quality control methods in order to select materials of the right quality are lacking. 'Amukkara choornam' is a polyherbal Siddha formulation used for gastritis, spleen enlargement, leucorrhoea, hiccups, anaemia...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.497147
更新日期:2010-12-01 00:00:00
abstract::The ethanol extract of Stellera chamaejasme roots exhibited significant bioactivity against Peries rapae. In the course of a search for the active compounds, S-(+)-1,5-diphenyl-3-hydroxy-1-pentanone (1) was isolated and this compound has never been found before in S. chamaejasme as far as we known. The structure was e...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701782536
更新日期:2008-03-10 00:00:00
abstract::Cynomorium coccineum is a non-photosynthetic plant that grows in Mediterranean countries and that is amply used in the traditional medicine. The aim of this study was to extend previous studies on the chemical and biological properties of C. coccineum, evaluating the potential antiviral and antiproliferative activity ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1678613
更新日期:2019-10-17 00:00:00
abstract::Epicatechin (EC) is the most effective compound in Euonymus alatus (Thunb.)Sieb, and possesses a series of benefits, including anti-inflammatory, antioxidant, antiobesity and anticancer effects. In this study, we investigated the protective effects of EC in Acetaminophen(N-acetyl-p-aminophenol, APAP)-induced acute liv...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1503261
更新日期:2020-03-01 00:00:00
abstract::Phytochemical study on the 95% ethyl alcohol extract of stems of Chenopodium ambrosioides resulted in the isolation of two new polyol monoterpenes, 4-hydroxy-4(α or β)-isopropyl-2-methyl-2-cyclohexen-1-one (1) and 1-methyl-4β- isopropyl-1-cyclohexene-4α,5α,6α-triol (2), together with five known compounds, (1S,2S,3R,4S...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1314278
更新日期:2017-11-01 00:00:00
abstract::Dunaliine A (1), a new amino diketone, has been isolated from the leaves of Desmos dunalii together with four known dihydrochalcones: 2',4-dihydroxy-4',6'-dimethoxy-3',5'-dimethyldihydrochalcone (2), 2',4-dihydroxy-4',6'-dimethoxydihydrochalcone (3), 2',4-dihydroxy-4',5',6'-trimethoxydihydrochalcone (4) and 2',4-dihyd...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802323743
更新日期:2009-01-01 00:00:00
abstract::This study was designed to characterise the effects of evodiamine on intestinal contractility and reveal the correlated mechanisms. Evodiamine (2.5-80.0 μM) increased normal jejunal contractility and jejunal hypocontractility established under a variety of experimental conditions. Evodiamine-exerted stimulatory effect...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.947485
更新日期:2015-01-01 00:00:00
abstract::Leaves of Kalanchoe pinnata are used worldwide for healing skin wounds. This study aimed to develop and compare two creams containing a leaf aqueous extract of K. pinnata (KP; 6%) and its major flavonoid [quercetin 3-O-α-L-arabinopyranosyl-(1→2)-α-L-rhamnopyranoside] (0.15%). Both creams were topically evaluated in a ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1817012
更新日期:2020-09-14 00:00:00
abstract::In this study the antioxidant and cytotoxicity activity of the Adonidia merrillii fruits were investigated using different solvent polarities (methanol, ethyl acetate and water). The results showed that the total phenolic and flavonoid contents of the methanolic extract was higher compare with other extract with respe...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1448810
更新日期:2019-09-01 00:00:00
abstract::The present work describes the metabolites produced by a strain identified as Streptomyces youssoufiensis, whose secondary metabolites profile has not been studied so far. The crude ethyl acetate extract was analyzed by high performance liquid chromatography-electrospray ionization mass spectrometry, leading to the de...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1446014
更新日期:2019-01-01 00:00:00
abstract::Immuno-therapies are gaining more importance to treat certain forms of cancer. The goal of therapies is to enhance person's own IgG, IgA, IgM, IgD, IgE and macrophages to combat with neoplastic cells hence the effectiveness of the immune system. Since, early civilization mushrooms are considered as potent food as well...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1466129
更新日期:2019-09-01 00:00:00
abstract::A novel isoindole alkaloid named oleraisoindole (1), together with six known compounds, 7'-ethoxy-trans-feruloyltyramine (2), N-trans-feruloyltyramine (3), N-trans-feruloyl-3-methoxytyramine (4), N-trans-p-coumaroyltyramine (5) aurantiamide (6) and ferulic acid methyl ester (7) were isolated from Portulaca oleracea L....
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1419226
更新日期:2018-10-01 00:00:00
abstract::This study describes the seasonal composition and the antibacterial, antioxidant and anticholinesterase activity of the essential oil from Eugenia brasiliensis leaves. Analysis by using GC allowed the identification of 40 compounds. It was observed that the monoterpenes varied more (42%) than the sesquiterpenes (14%),...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.958736
更新日期:2015-02-01 00:00:00
abstract::Cultivation of the marine-derived Aspergillus versicolor MCCC 3A00080 with the addition of a histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), significantly enhanced the diversity of secondary metabolites. From the culture treated, a new biphenyl derivative, named versiperol A (1), along with two ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1465423
更新日期:2019-04-01 00:00:00