Three alkaloids from Reineckia carnea herba and their antitussive and expectorant activities.

Abstract:

:Three alkaloids, (3-chloro-2-hydroxypropyl) trimethylammonium chloride (1), p-(acetylamino)-phenol (2) and 4,4'-diacetamidodiphenyl ether (3), were isolated from Reineckia carnea herba. Their structures were determined by detailed analysis of their 1D and 2D NMR spectra and MS. Compounds 1 and 3 were new natural products. Compound 2 was isolated for the first time from the Reineckia genus. Compound 1 displayed significant in vivo antitussive and expectorant activities.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Wang J,Han N,Wang Y,Wang Y,Liu Z,Wang Y,Yin J

doi

10.1080/14786419.2014.900618

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

1306-9

issue

16

eissn

1478-6419

issn

1478-6427

journal_volume

28

pub_type

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