Abstract:
:One new furofuran lignan 2-methoxy-9β-hydroxydiasesamin (1), and four analogues (2-5), together with eight alkaloids (6-13), were isolated from the ethanol extract of the aerial part of Clinacanthus nutans. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. All the compounds were isolated from the genus of Clinacanthus for the first time. In addition, lignans isolated from C. nutans was reported for the first time. Compound 1 exhibited modest activity against three human tumor cell lines Hela, MCF-7, and A549, with IC50 values of 68.55, 60.00, and 59.17 μM, respectively.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Diao HZ,Chen WH,Cao J,Shao TM,Song XP,Han CRdoi
10.1080/14786419.2018.1475375subject
Has Abstractpub_date
2019-05-01 00:00:00pages
1317-1321issue
9eissn
1478-6419issn
1478-6427journal_volume
33pub_type
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