Furofuran lignans and alkaloids from Clinacanthus nutans.

Abstract:

:One new furofuran lignan 2-methoxy-9β-hydroxydiasesamin (1), and four analogues (2-5), together with eight alkaloids (6-13), were isolated from the ethanol extract of the aerial part of Clinacanthus nutans. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. All the compounds were isolated from the genus of Clinacanthus for the first time. In addition, lignans isolated from C. nutans was reported for the first time. Compound 1 exhibited modest activity against three human tumor cell lines Hela, MCF-7, and A549, with IC50 values of 68.55, 60.00, and 59.17 μM, respectively.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Diao HZ,Chen WH,Cao J,Shao TM,Song XP,Han CR

doi

10.1080/14786419.2018.1475375

subject

Has Abstract

pub_date

2019-05-01 00:00:00

pages

1317-1321

issue

9

eissn

1478-6419

issn

1478-6427

journal_volume

33

pub_type

杂志文章
  • Bioactive compounds of inhibiting xanthine oxidase from Selaginella labordei.

    abstract::Four flavone compounds were isolated from the effective fractions inhibiting xanthine oxidase (XOD) of the medicinal plant Selaginella labordei with anti-virus activity, and the structures were elucidated as 4'-methylether robustaflavone (1), robustaflavone (2), eriodictyol (3) and amentoflavone (4). The 50% inhibitor...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410802228736

    authors: Tan WJ,Xu JC,Li L,Chen KL

    更新日期:2009-01-01 00:00:00

  • Determination of the derivative from ginkgolide B.

    abstract::A new compound decomposed from ginkgolide B(GB) is discovered and identified by MS and UV spectrum. It is the dehydrate of GB, which was named as ginkgolide K before. Differently, it cannot exist independently, but only in equilibrium with GB. It is found first time that 3-hydroxy is active in some solvent. ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410601130547

    authors: Yuan C,Pan J,Hu X

    更新日期:2008-01-01 00:00:00

  • Survey of 2,11-cyclized cembranoids from Caribbean sources.

    abstract::This review covers the literature published since the report of the first compound to December 2006, for marine natural 2,11-cyclized cembranoids isolated from Caribbean sources, with 30 citations, most of them from 2000 to 2006, referring to compounds isolated from the Caribbean gorgonian octocorals Briareum asbestin...

    journal_title:Natural product research

    pub_type: 杂志文章,评审

    doi:10.1080/14786410701760797

    authors: Cóbar OM

    更新日期:2009-01-01 00:00:00

  • Unexpected formation of hydroxybiphenylmethane derivatives and some new observations on Labat test.

    abstract::An unexpected synthesis of symmetrical hydroxybiphenylmethanes involving the reaction of 2-hydroxyphenyl benzyl ketones with ethoxymethyl chloride has been observed. Some new interesting observations of Labat test on colorimetric detection of bichalconyloxy, bichalconyl and biflavonylmethanes having oxygenated ortho p...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410600917902

    authors: Kukreja G,Campiani G,Khurana JM,Joshi BP,Grover SK

    更新日期:2006-10-01 00:00:00

  • Antiproliferative activity and chemical constituents of Lonchocarpus cultratus (Fabaceae).

    abstract::The aerial parts of L. cultratus were submitted to a phytopharmacological investigation in order to isolate and identify the major secondary metabolites and evaluate its crude extract, fractions and isolated compounds for antiproliferative activity. Seven compounds were isolated and identified as the chalcones 2',4'-d...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1647427

    authors: da Silva Landim EMBM,Ruiz ALTG,de Carvalho JE,Pomini AM,Pastorini LH,Oliveira Santin SM

    更新日期:2019-08-12 00:00:00

  • Chemical constituents and antitumor activity from Paris polyphylla Smith var. yunnanensis.

    abstract::Eleven compounds were isolated from the rhizomes of Paris polyphylla Smith var. yunnanensis. Their structures were elucidated on the basis of rigorous 1D and 2D NMR experiments as well as comparison with the literature data. To the best of our knowledge, compound 1 was only predicted by UPLC/Q-TOF MSE and the NMR spec...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2016.1219861

    authors: Jing S,Wang Y,Li X,Man S,Gao W

    更新日期:2017-03-01 00:00:00

  • Effect of Momordica dioica Roxb on gentamicin model of acute renal failure.

    abstract::The ethanolic extract of the fruits of Momordica dioica was studied for its protective and curative effect against gentamicin-induced acute renal injury in albino rats of both sexes. Gentamicin intoxicated group showed significant increase in blood urea (69.48 +/- 4.34) and serum creatinine (3.017 +/- 0.208) from norm...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410802267569

    authors: Jain A,Singhai AK

    更新日期:2010-09-01 00:00:00

  • Estimation of the influence of the environmental factors on the accumulation of phytochemicals and antioxidant capacity in the ivy leaves (Hedera helix L.).

    abstract::This study aimed at evaluating the impact of environmental factors on the accumulation of various components in Hedera helix L. folium collected from different European countries. The obtained results of studied samples showed that the antioxidant capacities were in the range of 0.027 to 0.688 mg/g. Contents of active...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1843029

    authors: Bezruk I,Materiienko A,Gubar S,Proskurina K,Budanova L,Ivanauskas L,Georgiyants V

    更新日期:2020-11-04 00:00:00

  • Matrix solid-phase dispersion as a tool for phytochemical and bioactivities characterisation: Crataegus oxyacantha L._A case study.

    abstract::The use of a matrix solid-phase dispersion (MSPD) process to extract polyphenols from hawthorn (Crataegus oxyacantha L.) a deciduous shrub with an expected rich phytochemical profile, has been evaluated. MSPD extracts of fruits and leaves have an outstanding content of polyphenols, although the particular phenolic pro...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1326040

    authors: Benabderrahmane W,Lores M,Lamas JP,Benayache S

    更新日期:2018-05-01 00:00:00

  • A novel and efficient synthesis of 3,4-dihydroxyphenylacetic ester and amide derivatives/conjugates and assessment of their antioxidant activity.

    abstract::Phenolic acids, a sub-class of polyphenols, are widely studied. By contrary, 3,4-dihydroxyphenylacetic acid is scarcely studied. For this purpose, a series of 3,4-dihydroxyphenylacetic acid ester and amide derivatives/conjugates were synthesised for the first time. A systematic study has been performed to quantitative...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1342090

    authors: Pagoni A,Vassiliou S

    更新日期:2018-06-01 00:00:00

  • Isolation and structural characterization of a non-diketopiperazine phytotoxin from a potato pathogenic Streptomyces strain.

    abstract::Two Streptomyces spp. strains responsible for potato common scab infections in Uruguay which do not produce diketopiperazines were identified through whole-genome sequencing, and the virulence factor produced by one of them was isolated and characterized. Phylogenetic analysis showed that both pathogenic strains can b...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1511554

    authors: Lapaz MI,López A,Huguet-Tapia JC,Pérez-Baldassari MF,Iglesias C,Loria R,Moyna G,Pianzzola MJ

    更新日期:2019-10-01 00:00:00

  • A new lanostane-type triterpene and sesquiterpene lactones from Vernonia leopoldii and their in vitro cytotoxicity.

    abstract::Investigation of the aerial parts of Vernonia leopoldii (Sch. Bip.) Vatke afforded a new lanostane-type triterpene along with known hirsutinolide-type sesquiterpene lactones and flavonoid glycosides, all are identified for the first time in this species. The new compound was identified as lanost-3β, 23S-dihydroxy-22(3...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2015.1062004

    authors: Marzouk AM,Abd Elhalim OB

    更新日期:2016-01-01 00:00:00

  • Effect of Andrographis paniculata leaf extract on wound healing in rats.

    abstract::This work was carried out to study the effect of topical application of Andrographis paniculata on the rate of wound enclosure and its histological features. A wound was created in four groups of rat in posterior neck region. Blank placebo was applied topically to the wounds of Group 1. Groups 2 and 3 were dressed wit...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2010.496114

    authors: Al-Bayaty FH,Abdulla MA,Abu Hassan MI,Ali HM

    更新日期:2012-01-01 00:00:00

  • Antiproliferative and antiviral activity of methanolic extracts from Sardinian Maltese Mushroom (Cynomorium coccineum L.).

    abstract::Cynomorium coccineum is a non-photosynthetic plant that grows in Mediterranean countries and that is amply used in the traditional medicine. The aim of this study was to extend previous studies on the chemical and biological properties of C. coccineum, evaluating the potential antiviral and antiproliferative activity ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1678613

    authors: Vascellari S,Zucca P,Perra D,Serra A,Piras A,Rescigno A

    更新日期:2019-10-17 00:00:00

  • Antibacterial activity of prenylated benzopyrans from Peperomia obtusifolia (Piperaceae).

    abstract::Peperomia obtusifolia is a herbaceous perennial plant native to the Americas reported as a traditional medicine to treat snake bites and as a skin cleanser. The bioassay-guided fractionation of crude extracts from aerial parts of P. obtusifolia against a panel of clinically important fungi and bacteria, showed that he...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1628751

    authors: Ruiz Mostacero N,Castelli MV,Cutró AC,Hollmann A,Batista JM Jr,Furlan M,Valles J,Fulgueira CL,López SN

    更新日期:2019-06-14 00:00:00

  • Antiliperoxidant activity of pomegranate peel extracts on lard.

    abstract::Phenolics were extracted from powdered pomegranate peel using water, methanol, acetone and ethyl acetate (EtOAc), respectively. The antiliperoxidant activity of the extracts on lard was studied by peroxide value method. All the extracts showed enhanced inhibitory effect on lard peroxidation with the increase of phenol...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410601130422

    authors: Zhang Q,Jia D,Yao K

    更新日期:2007-03-01 00:00:00

  • In vitro anti-enteroviral activity of stilbenoids isolated from the leaves of Macaranga barteri.

    abstract::The anti-enteroviral activity of three stilbenoids isolated from the leaves of Macaranga barteri was investigated using the cytopathic effect reduction assay. The stilbenes were inactive against echovirus E13 but showed activity against echoviruses E7 and E19. In particular, vedelianin (2), schweinfurthin G (3) and ma...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1644505

    authors: Segun PA,Ogbole OO,Akinleye TE,Faleye TOC,Adeniji AJ

    更新日期:2019-07-25 00:00:00

  • Polyprenyl-hydroquinones and -furans from three marine sponges inhibit the cell cycle regulating phosphatase CDC25A.

    abstract::The CDC25 phosphatases regulate the cell division cycle by controlling the activity of cyclin-dependent kinases. While screening for inhibitors of phosphatases among natural products we repeatedly found that some polyprenyl-hydroquinones and polyprenyl-furans (furanoterpenoids) (furospongins, furospinosulins) were pot...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/1478641031000111534

    authors: Erdogan-Orhan I,Sener B,de Rosa S,Perez-Baz J,Lozach O,Leost M,Rakhilin S,Meijer L

    更新日期:2004-02-01 00:00:00

  • Phytochemical, cytotoxic and chemotaxonomic study on Ajuga forrestii Diels (Labiatae).

    abstract::A phytochemical investigation of Ajuga forrestii Diels led to the isolation of 14 compounds, including eight neo-clerodane diterpenes (1-8), two phytoecdysteroids (9, 11), one stigmastane sterol (10) and three iridoid glycosides (12-14). The structures of these compounds were identified by spectroscopic methods and a ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1371161

    authors: Chen T,Diao QY,Yu HZ,Jiao CL,Ruan J

    更新日期:2018-04-01 00:00:00

  • Isolation of a new compound, 2-butanone 4-glucopyranoside 6'-O-gallate and other 8 compounds from the anti-inflammatory leave extracts of Memecylon edule Roxb.

    abstract::This present study was designed to isolate the compounds of Memecylon edule. The chemical compounds were purified by chromatographic methods and their structures were established on the basis of spectroscopic analyses (UV, MS and NMR). The major isolated compounds were tested for anti-inflammatory activity. The methan...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2016.1253074

    authors: Nualkaew S,Thongpraditchote S,Wongkrajang Y,Umehara K,Noguchi H

    更新日期:2017-06-01 00:00:00

  • Isolation of 2,5-diketopiperazines from Lysobacter capsici AZ78 with activity against Rhodococcus fascians.

    abstract::Inhibitory activity of the biocontrol bacterial strain Lysobacter capsici AZ78 is related to the production of cyclo(l-Pro-l-Tyr), a 2,5-diketopiperazine with in vitro and in vivo toxic activity against Phytophthora infestans and Plasmopara viticola. Further investigation of culture filtrate organic extracts showed it...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1756803

    authors: Cimmino A,Bejarano A,Masi M,Puopolo G,Evidente A

    更新日期:2020-04-30 00:00:00

  • Xanthones from Garcinia mangostana (Guttiferae).

    abstract::Studies on the stem of Garcinia mangostana have led to the isolation of one new xanthone mangosharin (1) (2,6-dihydroxy-8-methoxy-5-(3-methylbut-2-enyl)-xanthone) and six other prenylated xanthones, alpha-mangostin (2), beta-mangostin (3), garcinone D (4), 1,6-dihydroxy-3,7-dimethoxy-2-(3-methylbut-2-enyl)-xanthone (5...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410500463114

    authors: Ee GC,Daud S,Taufiq-Yap YH,Ismail NH,Rahmani M

    更新日期:2006-10-01 00:00:00

  • Comparative analysis of chemical constituents and bioactivities of the extracts from leaves, seed coats and embryoids of Ginkgo biloba L.

    abstract::A total of 25 compounds including terpenoids, flavonoids, biflavonoids and ginkgolic acids were identified and quantified with a reliable, simple, and simultaneous method from Ginkgo leaves, seed coats and embryoids with different tree ages (approximately identified as 25, 500, 1000 and 2000 years). Leaves had the hig...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1788020

    authors: Chen X,Zhong W,Shu C,Yang H,Li E

    更新日期:2020-07-01 00:00:00

  • New iridoids from the roots of Valeriana jatamansi Jones.

    abstract::Two new iridoids namely valerialloside A and valerianoside A (1 and 2) along with five known compounds (3-7) were isolated from the roots of Valeriana jatamansi Jones. The structure of new compounds were determined using 1D and 2D NMR including 1H-1H COSY, HSQC, HMBC and NOESY spectroscopic techniques. ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1858412

    authors: Maurya AK,Kumar A,Agnihotri VK

    更新日期:2020-12-09 00:00:00

  • A new flavonoid and sulphur-containing amides from Glycosmis chlorosperma.

    abstract::A new flavonoid, dihydroglychalcone-A, was isolated from the leaves extract of Glycosmis chlorosperma in addition to two known sulphur-containing amides, dambullin and gerambullin. The structure of the new compound was assigned as 2'-hydroxy-4,6'-dimethoxy-3',4'-(2",2"-dimethylpyrano)dihydrochalcone. The extract of th...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/1057563031000122121

    authors: Rahmani M,Leng KW,Ismail HB,Hin TY,Sukari MA,Ali AM,Kulip J

    更新日期:2004-02-01 00:00:00

  • Dunaliine A, a new amino diketone from Desmos dunalii (Annonaceae).

    abstract::Dunaliine A (1), a new amino diketone, has been isolated from the leaves of Desmos dunalii together with four known dihydrochalcones: 2',4-dihydroxy-4',6'-dimethoxy-3',5'-dimethyldihydrochalcone (2), 2',4-dihydroxy-4',6'-dimethoxydihydrochalcone (3), 2',4-dihydroxy-4',5',6'-trimethoxydihydrochalcone (4) and 2',4-dihyd...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410802323743

    authors: Awang K,Abdullah Z,Mukhtar MR,Litaudon M,Jaafar FM,Hadi AH,Thomas NF

    更新日期:2009-01-01 00:00:00

  • Isolation of antibacterial diterpenoids from Cryptomeria japonica bark.

    abstract::The aims of the present study were to determine the antibacterial activity of bark extract of Cryptomeria japonica D. Don and to isolate potential antibacterial constituents. The results showed that the ethanolic extract of C. japonica bark possessed a good antibacterial activity. Nine compounds including seven diterp...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410802267510

    authors: Li WH,Chang ST,Chang SC,Chang HT

    更新日期:2008-01-01 00:00:00

  • Microwave assisted henna organic dyeing of polyester fabric: a green, economical and energy proficient substitute.

    abstract::The proposed work, aims to provide a "green" and cutting-edge technique for the mordanting and dyeing of polyester fabric with natural henna dye using the advanced technology of micro waves. For providing a complete "green" and ecofriendly dyeing process, lemon was used as a natural bio mordant with micro waves and re...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1619721

    authors: Arain RA,Ahmad F,Khatri Z,Peerzada MH

    更新日期:2021-01-01 00:00:00

  • Two new monoterpene glucosides from Xanthium strumarium subsp. sibiricum with their anti-inflammatory activity.

    abstract::Two new monoterpene glucosides: xanmonoter A (1) and xanmonoter B (2) were isolated from Xanthium strumarium. Their structures were elucidated on the basis of 1D and 2D NMR, MS and CD analysis. Compounds 1 and 2 were tested for their anti-inflammatory activity with IC50 values of 17.4, 22.1 μM, respectively. ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1479701

    authors: Jiang H,Xing X,Yan M,Guo X,Yang L,Yang L

    更新日期:2019-12-01 00:00:00

  • Phytotoxic metabolites from Stilbocrea macrostoma, a fungal pathogen of Quercus brantii in Iran.

    abstract::Two phytotoxic furan derivatives were isolated, together with the well-known fungal and plant phytotoxin tyrosol, from the culture filtrates of Stilbocrea macrostoma. This fungal pathogen isolated from Quercus brantii trees induced wood necrosis and decline symptoms on the host plant in Iran. The two furan derivatives...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1797731

    authors: Di Lecce R,Bashiri S,Masi M,Alioto D,Tuzi A,Abdollahzadeh J,Evidente A

    更新日期:2020-10-05 00:00:00