A new triterpenoid saponin from the roots of Silene viscidula.

abstract：:These are the days when one would go online first seeking home remedies before seeing a doctor. Apple cider vinegar (ACV) is one such popular yet scientifically under-validated remedy. Our results prove the unequivocal antimicrobial activity of ACV to be true at full strength concentrations. However, the activity cann...

journal_title：Natural product research

authors： Gopal J,Anthonydhason V,Muthu M,Gansukh E,Jung S,Chul S,Iyyakkannu S

更新日期：2019-03-01 00:00:00

abstract：:Alternanthera brasiliana is popularly known as 'penicillin' and used as an anti-inflammatory and for wound healing. The objective of this work was the phytochemical study of the species by analytical techniques such as LC-MS/MS and GC-MS. Twenty-seven compounds were identified, five by LC-MS and 22 by GC-MS analysis. ...

journal_title：Natural product research

authors： Alencar Filho JMT,Teixeira HAP,Sampaio PA,Pereira ECV,Amariz IAE,Rolim Neto PJ,Rolim LA,Araújo ECDC

更新日期：2020-02-01 00:00:00

abstract：:Camptothecin (CPT), the derivatives of which are used clinically for the treatment of metastatic colon cancer, is isolated from intact plants that can be subjected to environmental fluctuations. In vitro cultures may be an alternate and continuous source for year-round production of CPT. Since CPT production by undiff...

journal_title：Natural product research

authors： Kamble S,Gopalakrishnan R,Eapen S

更新日期：2011-10-01 00:00:00

abstract：:In this study, a methanolic extract of Betula pendula leaves (BLE) was investigated for its gastroprotective effects against 90% ethanol-induced ulcer in rats. Oral pretreatment of rats with BLE (100, 200 and 400 mg kg(- 1)) significantly reduced the incidence of gastric lesions induced by ethanol administration as co...

journal_title：Natural product research

authors： Germanò MP,Cacciola F,Donato P,Dugo P,Certo G,D'Angelo V,Mondello L,Rapisarda A

更新日期：2013-01-01 00:00:00

abstract：:In this study, Moringa oleifera flower extract and a trypsin inhibitor (MoFTI) isolated from it were evaluated for anti-protozoal activity against Trypanosoma cruzi and cytotoxicity to mammalian cells. The presence of flavonoids was remarkable in the HPLC fingerprints of the extract at 254 and 360 nm. Amino acid seque...

journal_title：Natural product research

authors： Pontual EV,Pires-Neto DF,Fraige K,Higino TMM,Carvalho BEA,Alves NMP,Lima TA,Zingali RB,Coelho LCBB,Bolzani VS,Figueiredo RCBQ,Napoleão TH,Paiva PMG

更新日期：2018-12-01 00:00:00

abstract：:This study aimed at evaluating the impact of environmental factors on the accumulation of various components in Hedera helix L. folium collected from different European countries. The obtained results of studied samples showed that the antioxidant capacities were in the range of 0.027 to 0.688 mg/g. Contents of active...

journal_title：Natural product research

authors： Bezruk I,Materiienko A,Gubar S,Proskurina K,Budanova L,Ivanauskas L,Georgiyants V

更新日期：2020-11-04 00:00:00

abstract：:Neuroprotection under conditions of oxygen stress of two C21 steroidal glycosides, cynsaccatol Q (1) and saccatol K (2), isolated from Cynanchum auriculatum Royle ex Wight, and their potential mechanisms were studied using the model of H2O2-induced damage on PC12 cells in this paper. Experiments showed that compounds ...

journal_title：Natural product research

authors： Zhang M,Wang D,Li B

更新日期：2019-07-02 00:00:00

abstract：:The chemical investigation of the leaves and stem bark of Acacia polyacantha (Fabaceae) led to the isolation of a new oleanane-type triterpenoid saponin named polyacanthoside A 1 together with fifteen known compounds. Their structures were established from spectral , mainly HRESIMS, 1D NMR and 2D NMR and by comparison...

journal_title：Natural product research

authors： Fotso W G,Na-Iya J,Mbaveng T A,Ango Yves P,Demirtas I,Kuete V,Samuel Y,Ngameni B,Efferth T,Ngadjui T B

更新日期：2019-12-01 00:00:00

abstract：:The use of natural products as a diet supplement is increasing worldwide but sometimes is not followed by adequate sanitary controls and analyses. Twenty samples of pills and capsules of lyophilised cyanobacteria (blue-green algae), commercialised in Italy as dietary supplements, were found positive at the Vibrio fisc...

journal_title：Natural product research

authors： Bruno M,Fiori M,Mattei D,Melchiorre S,Messineo V,Volpi F,Bogialli S,Nazzari M

更新日期：2006-07-20 00:00:00

abstract：:The aim of study was to compare the content of phenolic acids and flavonoids in two cultivars of Lavandula angustifolia: 'Blue River' and 'Ellagance Purple', including flowers and leafy stalks. Total phenolics and total flavonoids contents were determined by UV-Vis spectroscopy. The contents of total phenolics in leaf...

journal_title：Natural product research

authors： Adaszyńska-Skwirzyńska M,Dzięcioł M

更新日期：2017-11-01 00:00:00

abstract：:Two new compounds, myrubol (1) and 3-oxo-11α-hydroxyfriedelane (2), were isolated from the roots of Myrica rubra along with eight known compounds (3-10). Their structures were determined through (1)H-NMR and (13)C-NMR spectral data, including 2-D experiments (HMBC, HMQC, (1)H-(1)H COSY and NOESY) and high-resolution m...

journal_title：Natural product research

authors： Li G,Wang D,Xu S

更新日期：2011-01-01 00:00:00

abstract：:Excessive accumulation of iron in the body can lead to organ injury. Some flavonoids which possess high affinity to iron can be used as iron chelators for curing iron overload diseases such as haemochromatosis. In this article, the effects of baicalin and quercetin on different mouse tissues (liver, kidney and heart) ...

journal_title：Natural product research

authors： Zhang Y,Gao Z,Liu J,Xu Z

更新日期：2011-07-01 00:00:00

abstract：:Phytochemical investigation of the twigs of Garcinia nobilis led to the isolation of a new xanthone, named l-hydroxy-2,5-dimethoxyxanthone (1), together with 15 known compounds (2-16). The structures of the new and known compounds were established by means of spectroscopic methods and by comparison with previously rep...

journal_title：Natural product research

authors： Fouotsa H,Tatsimo SJ,Neumann B,Michalek C,Mbazoa CD,Nkengfack AE,Sewald N,Lannang AM

更新日期：2014-01-01 00:00:00

abstract：:This study was designed to investigate possible antidepressant-like effects of the extract prepared from the flowers of Hypericum montbretti Spach. (Guttiferae, Clusiaceae). Phytochemical constituents of the methanolic extract were analysed by HPLC method. The main flavonoid component was detected as rutin, and anothe...

journal_title：Natural product research

authors： Can OD,Ismail IB,Oztürk Y,Oztürk N,Potoğlu-Erkara I,Sagratini G,Ricciutelli M,Vittori S,Maggi F

更新日期：2011-09-01 00:00:00

abstract：:Two new triterpene saponins, albidosides H (1) and I (2), along with the three known saponins were isolated from the barks of Acacia albida. Their structures were elucidated on the basis of extensive 1D- and 2D-NMR studies and mass spectrometry. Albidosides H (1) and I (2) were assayed for their cytotoxicity against H...

journal_title：Natural product research

authors： Tchoukoua A,Kuiate Tabopda T,Konga Simo I,Uesugi S,Ohno M,Kimura KI,Kwon E,Momma H,Shiono Y,Ngadjui BT

更新日期：2018-04-01 00:00:00

abstract：:A new 24-membered macrolide, 5'-epi-SPA-6952A (1), was isolated from the cultured broth of Streptomyces diastatochromogenes. The structure was elucidated by means of spectroscopic methods and comparing with literature data of the known 24-membered macrolide SPA-6952A. Compound 1 was found to show significant insectici...

journal_title：Natural product research

authors： Cao H,Liu W,Chang Y,Chen H,Zhang Y,Xu W,Tao L

更新日期：2019-03-01 00:00:00

abstract：:A new dimeric secoiridoids derivative, named japonicaside E, together with six known compounds were isolated from the flower buds of Lonicera japonica. The structures of these compounds were elucidated by the analyses of mass spectrometry and NMR spectroscopy. All compounds were evaluated for anti-inflammatory activit...

journal_title：Natural product research

authors： Ge W,Li HB,Fang H,Yang B,Huang WZ,Xiao W,Wang ZZ

更新日期：2019-01-01 00:00:00

abstract：:Three alkaloids, (3-chloro-2-hydroxypropyl) trimethylammonium chloride (1), p-(acetylamino)-phenol (2) and 4,4'-diacetamidodiphenyl ether (3), were isolated from Reineckia carnea herba. Their structures were determined by detailed analysis of their 1D and 2D NMR spectra and MS. Compounds 1 and 3 were new natural produ...

journal_title：Natural product research

authors： Wang J,Han N,Wang Y,Wang Y,Liu Z,Wang Y,Yin J

更新日期：2014-01-01 00:00:00

abstract：:In the present study, profiles of fatty acid, sn-2 fatty acid, triglyceride, phytochemical (including tocopherol/tocotrienol, phytosterol, flavonoid, carotenoid and polyphenol) and antioxidant capacity of extracts from the whole berry, pulp and seed of Hippophae¨ rhamnoides ssp. yunnanensis were investigated and compa...

journal_title：Natural product research

authors： Shi L,Zheng L,Zhao C,Jin Q,Wang X

更新日期：2019-12-01 00:00:00

abstract：:Edible flowers consumption has increased in recent years due to their rich content of healthy phytochemicals. The aim of this study was to analyse the chemical profile of Cucurbita pepo L. flowers, and to explore their antioxidant and hypoglycaemic properties. Moreover, in order to assess in vivo effects, biochemical ...

journal_title：Natural product research

authors： Morittu VM,Musco N,Mastellone V,Bonesi M,Britti D,Infascelli F,Loizzo MR,Tundis R,Sicari V,Tudisco R,Lombardi P

更新日期：2019-09-30 00:00:00

abstract：:A series of 4-hydroxy-3,4-dialkyl-2,6-diaryl-piperidine (7-12) have been synthesised by reduction of 3-alkyl-2,6-diarylpiperidin-4-one using the Grignard reagent. Structural assignments and conformational analysis of the compounds were established based on the spectral studies. All the piperdin-4-ol derivatives (7-12)...

journal_title：Natural product research

authors： Maruthavanan T,Venkatesan P

更新日期：2013-01-01 00:00:00

abstract：:Using a bioactivity-guided fractionation procedure, five cembranolides, 11-epi-sinulariolide acetate (1), 11-dehydrosinulariolide (2), sinulariolide (3), dihydrosinularin (4), and 3,4:8,11-bisepoxy-7-acetoxycembra-15(17)-en-1,12-olide (5), along with two nucleosides, 2'-deoxyadenosine and thymidine, were isolated from...

journal_title：Natural product research

authors： Hsieh PW,Chang FR,McPhail AT,Lee KH,Wu YC

更新日期：2003-12-01 00:00:00

abstract：:(+)-7-O-Methylisomiroestrol (MeI), a novel chromene, was discovered as a phytoestrogen in the Pueraria candollei var. mirifica (Airy Shaw & Suvat.) Niyomdham (PM) root having been used as an active agent against oestrogen depletion disorders. The identification of PM phytochemicals is crucial for the development of st...

journal_title：Natural product research

authors： Yusakul G,Juengsanguanpornsuk W,Sritularak B,Phaisan S,Juengwatanatrakul T,Putalun W

更新日期：2020-02-20 00:00:00

abstract：:Alkaloids and phenolic compounds are among the most biologically active natural products from the Jacobaea/Senecio genera (Asteraceae). To isolate original natural products directly from Jacobaea gigantea crude polar extracts, centrifugal partition chromatography (CPC) was used. Previously, we reported the phytochemic...

journal_title：Natural product research

authors： Mezache N,Derbré S,Laouer H,Richomme P,Séraphin D,Akkal S

更新日期：2019-08-01 00:00:00

abstract：:The phytochemical constituents in the aqueous methanolic leaf extract of Triclisia gilletii responsible for its nephroprotective potentials against ethane-1,2-diol induced nephrolithiasis as previously investigated in our laboratory were elucidated. The extract was prepared using 80% aqueous methanol in 72 h, Phytoche...

journal_title：Natural product research

authors： Olayeriju OS,Papetti A,Colombo R,Mannucci B,Olaleye MT,Akindahunsi AA

更新日期：2020-11-12 00:00:00

abstract：:Essential oils from aerial parts of Senecio nutans, Senecio viridis, Tagetes terniflora and Aloysia gratissima were analysed by GC-MS and their antifungal activities were assayed on toxigenic Fusarium and Aspergillus species. Sabinene (27.6 ± 0.1%), α-phellandrene (15.7 ± 0.3%), o-cymene (9.6 ± 0.2%) and β-pinene (6.1...

journal_title：Natural product research

authors： Galvez CE,Jimenez CM,Gomez ALA,Lizarraga EF,Sampietro DA

更新日期：2020-05-01 00:00:00

abstract：:A new androstanoid metabolite, 4α-methyl-9α-methoxyandrosta-8,15-diene-3,17-dione (1), was isolated from a soil fungus Curvularia borreriae (Pleosporaceae) strain HS-FG-237. Its structure was determined by extensive spectroscopic and X-ray diffraction analyses. Compound 1 exhibited poor cytotoxicity toward HCT-116 cel...

journal_title：Natural product research

authors： Liu LF,Zhang H,Qi H,Wang XM,Wang JD,Tan GS

更新日期：2017-05-01 00:00:00

abstract：:A new HPLC-DAD method was developed and validated for simultaneous determination of six main phenylethanoid glycosides (calceolarioside D, neocalceolarioside D, verbascoside, isoverbascoside, leucoseptoside A and martynoside) in the aerial parts of four Scutellaria L. taxa from flora of Turkey. All standard compounds ...

journal_title：Natural product research

authors： Bardakci H,Türköz Acar E,Kırmızıbekmez H

更新日期：2019-07-01 00:00:00

abstract：:A 70% ethanol extract from the leaves of Rosa davurica showed significant antioxidant activity in both superoxide anion and 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical-scavenging assays. Phytochemical study of this extract resulted in the isolation of eight compounds, including a new flavonoid glycoside. The che...

journal_title：Natural product research

authors： Ma F,Onoda T,Li W,Sasaki T,Ma L,Zhang Q,Koike K

更新日期：2013-01-01 00:00:00

abstract：:The chemical investigation of whole plants Euphorbia stracheyi Boiss from China led to the isolation of one new ent-kaurane diterpene, ent-Kaurane-16β,17,19-triol-3-one (1), along with three known ent-kaurane diterpenoids (2-4) as ent-Kaurane-3α,16β,17-triol (2)，ent-16S,17-dihydroxy-kaurane-3-one (3) and ent-3S,16S,17...

journal_title：Natural product research

authors： Liu T,Liang Q,Xiong NN,Dai LF,Wang JM,Ji XH,Xu WH

更新日期：2017-01-01 00:00:00