Wound healing cream formulated with Kalanchoe pinnata major flavonoid is as effective as the aqueous leaf extract cream in a rat model of excisional wound.

abstract：:The ability of the endophytic fungus Umbelopsis dimorpha SWUKD3.1410 to transform the triterpene nigranoic acid (3, 4-secocycloarta-4(28), 24-(Z)-diene-3, 26-dioic acid; 1) was investigated. Co-culture of nigranoic acid with U. dimorpha SWUKD3.1410 yielded six major products, including a new triterpene (2) and 5 known...

journal_title：Natural product research

authors： Wang L,Qin D,Zhang K,Huang Q,Liu S,Han MJ,Dong JY

更新日期：2017-06-01 00:00:00

abstract：:Two new triterpene saponins, namely notoginsenoside Ng5 (1) and notoginsenoside Ng6 (2) were isolated from the leaves of Panax notoginseng, along with five known ones. Their structures were determined by chemical methods, NMR and X-ray experiments. The absolute configuration of compound 3 with four sugar units was con...

journal_title：Natural product research

authors： Huang JW,Du YQ,Li CJ,Yang JZ,Ma J,Zang YD,Chen NH,Zhang DM

更新日期：2019-10-22 00:00:00

abstract：:The antitumour activity of the hydroalcoholic extract of the leaf (PCL) and stem bark (PCB) of Prosopis cineraria (L.) in Swiss albino mice was evaluated against an Ehrlich ascites carcinoma (EAC) tumour model. The activity was assessed using survival time, peritoneal cells, haematological studies, lipid peroxidation,...

journal_title：Natural product research

authors： Robertson S,Narayanan N,Raj Kapoor B

更新日期：2011-04-01 00:00:00

abstract：:Three alkaloids, (3-chloro-2-hydroxypropyl) trimethylammonium chloride (1), p-(acetylamino)-phenol (2) and 4,4'-diacetamidodiphenyl ether (3), were isolated from Reineckia carnea herba. Their structures were determined by detailed analysis of their 1D and 2D NMR spectra and MS. Compounds 1 and 3 were new natural produ...

journal_title：Natural product research

authors： Wang J,Han N,Wang Y,Wang Y,Liu Z,Wang Y,Yin J

更新日期：2014-01-01 00:00:00

abstract：:A new 1,4-napthoquinone derivative, namely (S)-(-)-3-(8-hydroxy-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)-3-(4-hydroxy-3-methoxyphenyl)-propionic acid methyl ester (1), was isolated from the roots of Juglans mandshurica Maxim. The structure was identified based on HR-ESI-MS, 1D and 2D NMR spectroscopic methods. ...

journal_title：Natural product research

authors： Jiang Z,Diao S,Li R,Zhou W,Sun J,Zhou Y,Jin Y,Jin M,Li G

更新日期：2018-05-01 00:00:00

abstract：:A new rare lumazine peptide, penilumamide E (1), together with 13 known compounds (2-14) were isolated from the fungus Aspergillus terreus. Their structures were identified by spectroscopic techniques. The relative configuration of 1 was confirmed by single-crystal X-ray diffraction analysis. Compound 10 exhibited ant...

journal_title：Natural product research

authors： Chaiyosang B,Kanokmedhakul K,Boonmak J,Youngme S,Kukongviriyapan V,Soytong K,Kanokmedhakul S

更新日期：2016-01-01 00:00:00

abstract：:The hexane and ethanol extracts from Himatanthus bracteatus (Apocynaceae) stems were evaluated for antiviral activity against Zika virus, yellow fever virus and dengue virus 2 and for cytotoxicity in Vero cells by MTT assay. The ethanol extract showed good antiviral activity against the three viruses with selective in...

journal_title：Natural product research

authors： da Silva ML,Stehmann JR,Serafim MSM,Vale VV,Gontijo DC,Brandão GC,Kroon EG,de Oliveira AB

更新日期：2019-11-20 00:00:00

abstract：:A continuous phytochemical study on the seeds of Senna obtusifolia (Syn.: Cassia obtusifolia) led to the isolation of a new anthraquinone analogue, obtusifolin-2-O-β-D-(6'-O-α,β-unsaturated butyryl)-glucopyranoside (1) and a new eurotinone analogue, epi-9-dehydroxyeurotinone-β-D-glucopyranoside (2). Their structures w...

journal_title：Natural product research

authors： Pang X,Wang LM,Zhang YC,Kang LP,Yu HS,Fan GW,Han LF

更新日期：2019-12-01 00:00:00

abstract：:Two new monoterpene glucosides: xanmonoter A (1) and xanmonoter B (2) were isolated from Xanthium strumarium. Their structures were elucidated on the basis of 1D and 2D NMR, MS and CD analysis. Compounds 1 and 2 were tested for their anti-inflammatory activity with IC50 values of 17.4, 22.1 μM, respectively. ...

journal_title：Natural product research

authors： Jiang H,Xing X,Yan M,Guo X,Yang L,Yang L

更新日期：2019-12-01 00:00:00

abstract：:The search for bioactive natural products from the rhizomes of Paris polyphylla (Trilliaceae) has resulted in the isolation of four known constituents, 1,5-dihydroxy-7-methoxy-3-methylanthraquinone (1), diosgenin-3-O-[alpha-L-rhamnopyranosyl-(1 --> 3)-beta-D-glucopyranoside] (2), diosgenin-3-O-[alpha-L-rhamnopyranosyl...

journal_title：Natural product research

authors： Devkota KP,Khan MT,Ranjit R,Lannang AM,Samreen,Choudhary MI

更新日期：2007-04-01 00:00:00

abstract：:Polyphyllin Ι is a steroidal saponin isolated from the rhizoma of Paris polyphylla. In the present study, we aimed to investigate the anticancer effects of polyphyllin Ι in colorectal cancer and to elucidate the potential underlying molecular mechanisms. Using, CCK8 assay, flow cytometry, laser confocal microscope ana...

journal_title：Natural product research

authors： Yu S,Wang L,Cao Z,Gong D,Liang Q,Chen H,Fu H,Wang W,Tang X,Xie Z,He Y,Peng C,Li Y

更新日期：2018-06-01 00:00:00

abstract：:The chemical composition of the methanol extract obtained from Araucaria cunninghamii Sweet. bark was determined by GC-MS analysis with its antioxidant and antibacterial potential, for the first time. A total of 73 compounds were identified and the extract was strongly characterised by Viridiflorene; Androstan-17-one,...

journal_title：Natural product research

authors： Kumar P,Sati SC,Khulbe K,Pant P,Tripathi AN,Sarvendra K

更新日期：2020-11-29 00:00:00

abstract：:A new denudatine-type C20-diterpenoid alkaloid, designated as sinchianine (1), together with eight known diterpenoid alkaloids, 12-acetyl-12-epi-napelline (2), 12-epi-napelline (3), neoline (4), talatisamine (5), 14-O-acetylsenbusine A (6) and benzoylaconine (7), songorine (8) and aconitine (9), were isolated from the...

journal_title：Natural product research

authors： Samanbay A,Zhao B,Aisa HA

更新日期：2018-10-01 00:00:00

abstract：:Protein kinase C (PKC) plays a key role in neurotransmission in the central nervous system, and targeting PKC domain is considered as a strategy to modulate the anaesthetic effects. In this study, we described a synthetic pipeline to perform high-throughput virtual screening against a large library of 3D structural na...

journal_title：Natural product research

authors： Zhao J,Zhou C

更新日期：2015-01-01 00:00:00

abstract：:The objective of this work was to produce and characterise nanoemulsions containing tucumã extract and to evaluate the performance of the nanostructure and the free compound regarding antitumor activity, cytotoxicity, and oxidative metabolism in NB4/APL cells. The nanoemulsions showed adequate physicochemical characte...

journal_title：Natural product research

authors： Copetti PM,Gündel SDS,de Oliveira PSB,Favarin FR,Ramos AP,Pintos FG,Pappis L,Gündel A,Machado AK,Ourique AF,Sagrillo MR

更新日期：2020-12-24 00:00:00

abstract：:A new highly oxygenated germacranolide, carcerlane A (1), together with four known highly oxygenated germacranolides (2-5), was isolated from an ethanol extract of the whole plant of Carpesium nepalense var. lanatum (C.B.Clarke) Kitam. The structures were determined by HRESIMS and extensive analysis of their spectrosc...

journal_title：Natural product research

authors： Yu YF,Li YQ,Wang RY,Liu X,Cui WB,Chen XH,Zhao CM,Qi FM,Zhang ZX,Fei DQ

更新日期：2020-10-22 00:00:00

abstract：:This manuscript describes the antioxidant activity of essential oil of Cinnamon (Cinnamomum zeylanicum) bark extracted by supercritical fluid extraction (SCFE), hydro distillation and steam distillation. The cinnamon bark essential oil exhibited a wide range of total phenolic contents, total flavonoid contents, reduci...

journal_title：Natural product research

authors： Saleem M,Bhatti HN,Jilani MI,Hanif MA

更新日期：2015-01-01 00:00:00

abstract：:The purpose of this study is the determination of chemical composition and antioxidant activity of essential oils (EOs) from Saussurea costus (Falc.) Lipsch. Roots have been collected on December of the first plant year (IY) and in April, August and December of the third plant year (I, 6B, D7). A GC analysis was carri...

journal_title：Natural product research

authors： Benedetto C,D'Auria M,Mecca M,Prasad P,Singh P,Singh S,Sinisgalli C,Milella L

更新日期：2019-08-01 00:00:00

abstract：:Cultivation of the marine-derived Aspergillus versicolor MCCC 3A00080 with the addition of a histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), significantly enhanced the diversity of secondary metabolites. From the culture treated, a new biphenyl derivative, named versiperol A (1), along with two ...

journal_title：Natural product research

authors： Zhu JX,Ding L,He S

更新日期：2019-04-01 00:00:00

abstract：:An activity-guided isolation and purification process was used to identify the l,l-diphenyl-2-picrylhydrazyl (DPPH) free radical-scavenging components of the food plant (Terminalia arjuna) of Antheraea mylitta. Dry leaves of T. arjuna were extracted with different solvents and tested for their antioxidant activity aga...

journal_title：Natural product research

authors： Singh PP,Chauhan SM

更新日期：2014-01-01 00:00:00

abstract：:A new C20-diterpenoid alkaloid carmichaedine (1) and six known alkaloids (2-7) were isolated from the lateral roots of Aconitum carmichaeli. Their structures were established on the basis of extensive spectroscopic analyses. Compound 1 exhibited potent antibacterial activity against Bacillus subtilis with minimum inhi...

journal_title：Natural product research

authors： Yu J,Yin TP,Wang JP,Mei RF,Cai L,Ding ZT

更新日期：2017-01-01 00:00:00

abstract：:A new sesquiterpenoid, malayscaphiol (1), and three known compounds, lupeol (2), lupenone (3) and stigmasterol (4), were isolated from the methanolic extract of the stem bark of Scaphium macropodum. The structures of the isolated compounds were determined using several spectroscopic methods, including UV-vis, FT-IR, 1...

journal_title：Natural product research

authors： Al Muqarrabun LM,Ahmat N,Aris SR,Shamsulrijal N,Baharum SN,Ahmad R,Rosandy AR,Suratman MN,Takayama H

更新日期：2014-01-01 00:00:00

abstract：:The chemical investigation of whole plants Euphorbia stracheyi Boiss from China led to the isolation of one new ent-kaurane diterpene, ent-Kaurane-16β,17,19-triol-3-one (1), along with three known ent-kaurane diterpenoids (2-4) as ent-Kaurane-3α,16β,17-triol (2)，ent-16S,17-dihydroxy-kaurane-3-one (3) and ent-3S,16S,17...

journal_title：Natural product research

authors： Liu T,Liang Q,Xiong NN,Dai LF,Wang JM,Ji XH,Xu WH

更新日期：2017-01-01 00:00:00

abstract：:A new thiodiketopiperzaine, tedanizaine A (1), together with six known ones, were isolated from the marine sponge Tedania sp. Their structures were determined by spectroscopic analyses. The absolute configuration of 1 was established by ECD calculation. Compound 1 was the second example of thiodiketopiperazine bearing...

journal_title：Natural product research

authors： Zhang H,Lai W,Guan ZB,Liao XJ,Zhao BX,Xu SH

更新日期：2020-04-01 00:00:00

abstract：:Analgesic and anti-inflammatory activities of the aqueous and ethanol extracts of Thespesia populnea Soland. ex. Correa (Malvaceae) leaves were evaluated in animal models. Orally-administered aqueous and ethanol extracts (100, 200 and 400 mg kg⁻¹ bw) showed significant analgesic activity in chemical-, mechanical- and ...

journal_title：Natural product research

authors： Ilavarasan R,Mohideen S,Venkataraman S

更新日期：2012-01-01 00:00:00

abstract：:The ethanolic extract of the fruits of Momordica dioica was studied for its protective and curative effect against gentamicin-induced acute renal injury in albino rats of both sexes. Gentamicin intoxicated group showed significant increase in blood urea (69.48 +/- 4.34) and serum creatinine (3.017 +/- 0.208) from norm...

journal_title：Natural product research

authors： Jain A,Singhai AK

更新日期：2010-09-01 00:00:00

abstract：:A new diterpenoid, 15-epi-(4E)-jatrogrossidentadione acetate, along with several known constituents has been isolated from the stem of Jatropha multifida. The structure of the new compound was settled by a detailed analysis of its 1D- and 2D-NMR spectra. ...

journal_title：Natural product research

authors： Das B,Satya Kumar A,Narayan Kumar J,Venugopal Raju T

更新日期：2010-10-01 00:00:00

abstract：:Oxygen radical absorbance capacity (ORAC) is a widely used hydrogen atom transfer-based method which measures the antioxidant capacity of natural products. ORAC values of oleaster (Elaeagnus angustifolia L.), which was extracted with ethanol/acetone (7:3, v/v), ethanol/water (1:1, v/v) and methanol/water (1:1, v/v) in...

journal_title：Natural product research

authors： Yalcin G,Sogut O

更新日期：2014-01-01 00:00:00

abstract：:Epicatechin (EC) is the most effective compound in Euonymus alatus (Thunb.)Sieb, and possesses a series of benefits, including anti-inflammatory, antioxidant, antiobesity and anticancer effects. In this study, we investigated the protective effects of EC in Acetaminophen(N-acetyl-p-aminophenol, APAP)-induced acute liv...

journal_title：Natural product research

authors： Wu H,Xie Y,Xu Y,Hu Z,Wan X,Huang H,Huang D

更新日期：2020-03-01 00:00:00

abstract：:Teucrium marum and T. subspinosum have been extracted with different polarity solvents, each crude extract was analysed with (1)H-NMR to compare the overall metabolic component. The polar extracts showed antioxidant activity in vitro. Verbascoside and arabinosyl-verbascoside were isolated and identified. Their concent...

journal_title：Natural product research

authors： Poli F,Serrilli AM,Scartezzini P,Muzzoli M,Maxia A,Ballero M,Serafini M,Bianco A

更新日期：2007-10-01 00:00:00