Phytochemical constituents, antimicrobial and antioxidant activities of Kumaun Himalayan Hoop Pine bark extract.

Abstract:

:The chemical composition of the methanol extract obtained from Araucaria cunninghamii Sweet. bark was determined by GC-MS analysis with its antioxidant and antibacterial potential, for the first time. A total of 73 compounds were identified and the extract was strongly characterised by Viridiflorene; Androstan-17-one, 3-ethyl-3-hydroxy-, (5α)-; 8-Isopropenyl-1,3,3,7-tetramethyl-bicyclo[5.1.0]oct-5-en-2-one; 3,6,9-Triethyl-3,6,9-trimethyl-tetracyclo[6.1.0.0 ∼ 2,4∼.0 ∼ 5,7∼]-nonane; Longifolenaldehyde; (-)-Caryophyllen-(I1); 2-hydroxymethyl-5-furfural; Methyl commate B; 3-Ethyl-3-hydroxyandrostan-17-one; 3-Hydroxybenzoic acid as the main components (55.39%). A. cunninghamii extract presents IC50, 53.52 µg/mL and 65.29 µg/mL using DPPH and H2O2 scavenging assay, respectively. The antibacterial activity of the extract was evaluated for eight microorganisms showed that the extract had a remarkable inhibitory potential with a mean zone diameter of inhibition ranging from 09 to 21 mm. The methanol extract of A. cunninghamii showed significant antibacterial activity against X. campestris (21 mm, ZOI) with MIC and MBC values 15.6 and 31.25 µg/mL, respectively.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Kumar P,Sati SC,Khulbe K,Pant P,Tripathi AN,Sarvendra K

doi

10.1080/14786419.2020.1851217

subject

Has Abstract

pub_date

2020-11-29 00:00:00

pages

1-5

eissn

1478-6419

issn

1478-6427

pub_type

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