Abstract:
:The chemical composition of the methanol extract obtained from Araucaria cunninghamii Sweet. bark was determined by GC-MS analysis with its antioxidant and antibacterial potential, for the first time. A total of 73 compounds were identified and the extract was strongly characterised by Viridiflorene; Androstan-17-one, 3-ethyl-3-hydroxy-, (5α)-; 8-Isopropenyl-1,3,3,7-tetramethyl-bicyclo[5.1.0]oct-5-en-2-one; 3,6,9-Triethyl-3,6,9-trimethyl-tetracyclo[6.1.0.0 ∼ 2,4∼.0 ∼ 5,7∼]-nonane; Longifolenaldehyde; (-)-Caryophyllen-(I1); 2-hydroxymethyl-5-furfural; Methyl commate B; 3-Ethyl-3-hydroxyandrostan-17-one; 3-Hydroxybenzoic acid as the main components (55.39%). A. cunninghamii extract presents IC50, 53.52 µg/mL and 65.29 µg/mL using DPPH and H2O2 scavenging assay, respectively. The antibacterial activity of the extract was evaluated for eight microorganisms showed that the extract had a remarkable inhibitory potential with a mean zone diameter of inhibition ranging from 09 to 21 mm. The methanol extract of A. cunninghamii showed significant antibacterial activity against X. campestris (21 mm, ZOI) with MIC and MBC values 15.6 and 31.25 µg/mL, respectively.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Kumar P,Sati SC,Khulbe K,Pant P,Tripathi AN,Sarvendra Kdoi
10.1080/14786419.2020.1851217subject
Has Abstractpub_date
2020-11-29 00:00:00pages
1-5eissn
1478-6419issn
1478-6427pub_type
杂志文章abstract::Biotransformation of corosolic acid (1) by Cochliobolus lunatus and Streptomyces asparaginoviolaceus afforded four metabolites, which were identified by using (1)H NMR, (13)C NMR, DEPT, HSQC, HMBC and NOESY spectral data. Biotransformation of corosolic acid by C. lunatus R.R. Nelson & Haasis CGMCC 3.4381 produced thre...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.955485
更新日期:2014-01-01 00:00:00
abstract::A new C20-diterpenoid alkaloid carmichaedine (1) and six known alkaloids (2-7) were isolated from the lateral roots of Aconitum carmichaeli. Their structures were established on the basis of extensive spectroscopic analyses. Compound 1 exhibited potent antibacterial activity against Bacillus subtilis with minimum inhi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1219863
更新日期:2017-01-01 00:00:00
abstract::A new diterpenoid glycoside, 14,15-dinor-labdan-13-one-8-O-alpha-L-arabinopyranoside (1), was isolated from Conyza blinii. The structure of this new arabinoside was elucidated on the basis of extensive NMR and HRMS spectroscopy. In addition, the presence of 3R-hydroxyoctadecanoic acid in C. blinii was reported for the...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701592232
更新日期:2008-04-15 00:00:00
abstract::Ginsenoside Re (G-Re) is a major ingredient of the ginseng bud. A novel and rapid method to isolate and purify G-Re from ginseng buds was established. The procedure involves solvent extraction of ginseng bud powder, then pre-purification with an active carbon column and purification by preparative HPLC (prep-HPLC). Ac...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.540577
更新日期:2012-01-01 00:00:00
abstract::A new furan derivative named 3-(5-oxo-2,5-dihydrofuran-3-yl) propanoic acid (1) was isolated for the first time. Its structure was elucidated by UV, IR, NMR, HR-ESI-MS and the single-crystal X-ray diffraction spectroscopic data. Meanwhile, the antifungal and antibacterial activities of compound 1 was tested, it exhibi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1501687
更新日期:2019-10-01 00:00:00
abstract::A new phthalide derivative, xylarphthalide A (1), along with two known compounds (-)-5-carboxylmellein (2) and (-)-5-methylmellein (3), were isolated from the endophytic fungus Xylaria sp. GDG-102 cultured from the Chinese medicinal plant Sophora tonkinensis. Their structures were identified by MS and NMR experiments,...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1311892
更新日期:2018-04-01 00:00:00
abstract::Five flavonoids were isolated from the ethyl acetate fraction of leaves of Sophora secundiflora; formononetin (1), 5-hydroxy-4'-methoxyflavone (2), genistein (3), 5-hydroxy-8-(1-hydroxy-1-methyl-ethyl)-2-(4-hydroxyphenyl)-4H-furo-[2, 3-h]-chromen-4-one (4) and ononin (5). Additionally, LC-ESI-MS/MS analysis of the eth...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1795853
更新日期:2020-07-22 00:00:00
abstract::The microbial transformation of androst-4-ene-3,17-dione (4-AD; I) by three fungal species, involved Fusarium solani BH1031, Aspergillus awamori MH18 and Mucor circinelloides W12, has been studied. The latter two fungi were studied for the first time on biotransformation of 4-AD. The main product obtained by Fusarium ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1636238
更新日期:2021-02-01 00:00:00
abstract::In this study, the efficiency of nanoporous aluminium wires as fibres for headspace solid-phase microextraction (HS-SPME) of volatile compounds from Lippia citriodora was investigated and compared with two anodised methods. The prepared fibres are durable with very good chemical and thermal stability which can be coup...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1233407
更新日期:2017-02-01 00:00:00
abstract::Chemical investigation of the Red Sea sponge Dragmacidon coccinea led to the isolation of a new nucleoside, dragmacidoside (1), along with eight known compounds: adenosine (2), inosine (3), deoxycytidine (4), methyl-α-d-glucopyranoside (5), clionasterol (6), stigmasterol (7), campesterol (8) and brassicasterol (9). Th...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.915828
更新日期:2014-01-01 00:00:00
abstract::This study discusses the similarities and differences between the antioxidant activities of some essential oils: thyme (Thymus vulgaris), basil (Ocimum basilicum), peppermint (Mentha piperita), clove (Caryophyllus aromaticus), summer savory (Satureja hortensis), sage (Salvia hispanica) and lemon (Citrus limon (L.) Bur...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.918121
更新日期:2014-01-01 00:00:00
abstract::The antitumour activity of the hydroalcoholic extract of the leaf (PCL) and stem bark (PCB) of Prosopis cineraria (L.) in Swiss albino mice was evaluated against an Ehrlich ascites carcinoma (EAC) tumour model. The activity was assessed using survival time, peritoneal cells, haematological studies, lipid peroxidation,...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.536159
更新日期:2011-04-01 00:00:00
abstract::New ent-trachylobane-3β-hydroperoxide (5) together with four known compounds, ricinine (1), trimethoxy ellagic acid (2), dimethoxy ellagic acid (3) and aleurotolic acid (4) were isolated from the methylene chloride fraction of the root bark of Chrozophora oblongifolia. The structures of these secondary metabolites wer...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1687477
更新日期:2019-11-06 00:00:00
abstract::Phytochemical reinvestigation on the whole plants of Derris laxiflora Benth. afforded two new diprenylated flavanones, derriflavanones B and C (1-2), together with thirty-two known compounds, including sixteen flavonoids (3-18), eleven aromatic compounds (19-29), and five chlorophylls (30-34). All known compounds were...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1576039
更新日期:2020-08-01 00:00:00
abstract::The chemical composition of the volatile extract (yield ≈ 0.13%, v/w) from the bark of Quercus leucotrichophora (Fagaceae) was analysed for the first time by GC-MS. Twenty-three constituents, amounting to 93.0% of the total detected contents of the volatile extract, were identified. The volatile extract contained appr...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.564584
更新日期:2012-01-01 00:00:00
abstract::Oxygen radical absorbance capacity (ORAC) is a widely used hydrogen atom transfer-based method which measures the antioxidant capacity of natural products. ORAC values of oleaster (Elaeagnus angustifolia L.), which was extracted with ethanol/acetone (7:3, v/v), ethanol/water (1:1, v/v) and methanol/water (1:1, v/v) in...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.913243
更新日期:2014-01-01 00:00:00
abstract::Twenty-one phenolic compounds (1-21) including dihydrocinnamic acid, isoflavonoids, flavonoids, coumestans, pterocarpans, chalcones, isoflavan and isoflaven, were isolated from the roots of Glycyrrhiza pallidiflora Maxim. Phloretinic acid (1), chrysin (6), 9-methoxycoumestan (8), isoglycyrol (9), 6″-O-acetylanonin (19...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1188094
更新日期:2017-02-01 00:00:00
abstract::Alkaloids and phenolic compounds are among the most biologically active natural products from the Jacobaea/Senecio genera (Asteraceae). To isolate original natural products directly from Jacobaea gigantea crude polar extracts, centrifugal partition chromatography (CPC) was used. Previously, we reported the phytochemic...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1493584
更新日期:2019-08-01 00:00:00
abstract::Two new C13-norsesquiterpenes claulanterpene A (1) and B (2), together with two known sesquiterpenes (3-4), were isolated from methanol extract of the stem and leaf of Clausena lansium collected from Qingyuan county, Guangdong Province, China. Their structures were elucidated on the base of extensive spectroscopic ana...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1741577
更新日期:2020-03-25 00:00:00
abstract::This paper addresses the application of infrared spectroscopy in combination with chemometrics to identify wall painting's binding medium while employing pattern recognition techniques to process FTIR data-set of complex samples. In this regard, based on the historical documents and previous researches, firstly 56 sta...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1108974
更新日期:2019-04-01 00:00:00
abstract::Edible flowers consumption has increased in recent years due to their rich content of healthy phytochemicals. The aim of this study was to analyse the chemical profile of Cucurbita pepo L. flowers, and to explore their antioxidant and hypoglycaemic properties. Moreover, in order to assess in vivo effects, biochemical ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1672067
更新日期:2019-09-30 00:00:00
abstract::Polyphenol concentrations were quantified by rapid resolution liquid chromatography/mass spectrometry in white table grape. The experimental vineyard was subjected to different kinds of water supply and supply rates. Samples from the same vineyards were also analysed after 6 weeks of storage in a refrigerator and afte...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.606623
更新日期:2012-01-01 00:00:00
abstract::Three new sesquiterpenes: 4-acrylic-6-methyl-α-tetralone (1), ainsliaea acid A (2) and ainsliaea acid B (3), together with 8 known compounds (4-11) were isolated from the whole herb of Ainsliaea glabra and their structures were established by means of 1D and 2D NMR spectroscopy and HR-ESIMS. Compounds 1-6 were tested ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1446134
更新日期:2019-01-01 00:00:00
abstract::The aim of this study was to explore the extract/fractions and compounds of Diospyros lotus against various Gram-positive and Gram-negative bacteria strain. The results showed marked susceptibility of extract and its fractions against test pathogens. Among them, chloroform fraction was most dominant and effective agai...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1013957
更新日期:2016-01-01 00:00:00
abstract::The chemical composition of the volatile organic compounds (VOCs) released from the leaves and flowers of Artemisia fragrans Willd. (Asteraceae) was investigated using headspace solid-phase microextraction (HS-SPME) coupled to gas chromatography (GC) and/or GS/mass spectrometry (GC/MS). The efficiency and reliability ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410903108951
更新日期:2010-08-01 00:00:00
abstract::A new sesquiterpenoid, malayscaphiol (1), and three known compounds, lupeol (2), lupenone (3) and stigmasterol (4), were isolated from the methanolic extract of the stem bark of Scaphium macropodum. The structures of the isolated compounds were determined using several spectroscopic methods, including UV-vis, FT-IR, 1...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.886211
更新日期:2014-01-01 00:00:00
abstract::This study aimed at evaluating the impact of environmental factors on the accumulation of various components in Hedera helix L. folium collected from different European countries. The obtained results of studied samples showed that the antioxidant capacities were in the range of 0.027 to 0.688 mg/g. Contents of active...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1843029
更新日期:2020-11-04 00:00:00
abstract::The latex of Ficus carica Linn. (Moraceae) has been shown to possess antiviral properties against some human viruses. To determine the ability of F. carica latex (F-latex) to interfere with the infection of caprine herpesvirus-1 (CpHV-1) in vitro, F-latex was resuspended in culture media containing 1% ethanol and was ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.918120
更新日期:2014-01-01 00:00:00
abstract::A new 24-membered macrolide, 5'-epi-SPA-6952A (1), was isolated from the cultured broth of Streptomyces diastatochromogenes. The structure was elucidated by means of spectroscopic methods and comparing with literature data of the known 24-membered macrolide SPA-6952A. Compound 1 was found to show significant insectici...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1405401
更新日期:2019-03-01 00:00:00
abstract::Two new compounds, identified as 3-(2-hydroxybenzyl)-6,8-dimethoxy-4H-chromen-4-one (1), named oleracone J and 3-(2-hydroxybenzyl)-6,8-dimethoxychroman-4-one (2), named oleracone K, were isolated from Portulaca oleracea L., and the structures of them were determined by spectroscopy, including one-dimensional and two-d...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1815742
更新日期:2020-09-03 00:00:00