Phenolic compounds from Glycyrrhiza pallidiflora Maxim. and their cytotoxic activity.

abstract：:A new cycloartane triterpene bisdesmoside, soulieoside T (1), and one known compound, oleanolic acid (2), were isolated from the ethanolic extract of the rhizomes of Actaea vaginata. Their structures were elucidated by spectroscopic methods and by comparison with data reported in the literature. Compound 1 was evaluat...

journal_title：Natural product research

authors： Zhang M,Yang Q,Zhang X,Wu H

更新日期：2019-12-10 00:00:00

abstract：:Artemisia herba-alba is widely used in traditional medicines for the treatment of several diseases. From the aerial parts organic extract of A. herba-alba, two new compounds, 1,3,8-trihydroxyeudesm-4-en-7α,11βH-12,6α-olide (1) and 5-β-​D-​glucopyranosyloxy​-​7-methoxy-​6H-​benzopyran-​2-​one (2), respectively, togethe...

journal_title：Natural product research

authors： Mohamed TA,Abd El Aty AA,Shahat AA,Abdel-Azim NS,Shams KA,Elshamy AA,Ahmed MM,Youns SHH,El-Wassimy TM,El-Toumy SA,Hegazy MF

更新日期：2019-07-31 00:00:00

abstract：:To search for possible cancer chemopreventive agents from natural sources, we performed primary screening of metabolites of Alternaria porri by examining their possible inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells. The et...

journal_title：Natural product research

authors： Horiuchi M,Tokuda H,Ohnishi K,Yamashita M,Nishino H,Maoka T

更新日期：2006-02-01 00:00:00

abstract：:The cholesteryl ester transfer protein (CETP), inhibition of which assists in maintaining a high level of high-density lipoprotein cholesterol in the blood, is a target for anti-atherosclerosis treatments. Orange monascus pigment was produced by a Monascus species in a 5 L jar fermenter and various derivative compound...

journal_title：Natural product research

authors： Jang H,Choe D,Shin CS

更新日期：2014-01-01 00:00:00

abstract：:An alternative method for the synthesis of the 8-methyl-1-tetralone from the commercially available 5-methoxy-1-tetralone has been developed. The transformation involves eight steps and affords an overall yield 25%. ...

journal_title：Natural product research

authors： Poon PS,Bedoya L,Churio GJ,Banerjee AK

更新日期：2014-01-01 00:00:00

abstract：:A series of 4-hydroxy-3,4-dialkyl-2,6-diaryl-piperidine (7-12) have been synthesised by reduction of 3-alkyl-2,6-diarylpiperidin-4-one using the Grignard reagent. Structural assignments and conformational analysis of the compounds were established based on the spectral studies. All the piperdin-4-ol derivatives (7-12)...

journal_title：Natural product research

authors： Maruthavanan T,Venkatesan P

更新日期：2013-01-01 00:00:00

abstract：:A new 1,4-napthoquinone derivative, namely (S)-(-)-3-(8-hydroxy-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)-3-(4-hydroxy-3-methoxyphenyl)-propionic acid methyl ester (1), was isolated from the roots of Juglans mandshurica Maxim. The structure was identified based on HR-ESI-MS, 1D and 2D NMR spectroscopic methods. ...

journal_title：Natural product research

authors： Jiang Z,Diao S,Li R,Zhou W,Sun J,Zhou Y,Jin Y,Jin M,Li G

更新日期：2018-05-01 00:00:00

abstract：:N-hexane and methanol extracts of Asystasia buettneri Lindau aerial parts exhibited antiproliferative activity on leukaemia blood carcinoma, K-562. Hexadecane (1), 1,3-propan-2-ol (9Z,12'Z,15″Z)-bis(doeicos-9,12,15-trienoate) (2), hydrocarbon, 2,3,3,10,23-pentamethyl tetraeicos-10,13,16-trien-1-ol (3), hexadecanoic ac...

journal_title：Natural product research

authors： Hamid AA,Aiyelaagbe OO,Negi AS,Luqman S,Kaneez F

更新日期：2018-09-01 00:00:00

abstract：:In this article, an ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry method was developed to detect the chemical structures of proanthocyanidins (PAs) from seed coats of Schisandra chinensis. The cleavage pathways of the compounds were revealed. The structures of S. chinensis PAs, in...

journal_title：Natural product research

authors： Yan T,Hu GS,Wang AH,Hong Y,Jia JM

更新日期：2014-01-01 00:00:00

abstract：:Phorbol esters (PEs) are diterpenes present in Jatropha curcas L. seeds and have a myriad of biological activities. Since PEs are toxic, they are considered to be futile in Jatropha-based biodiesel production chain. In the present study, the extracted PEs from Jatropha oil were used as a starting material to synthesis...

journal_title：Natural product research

authors： Devappa RK,Malakar CC,Makkar HP,Becker K

更新日期：2013-01-01 00:00:00

abstract：:Leaves of Kalanchoe pinnata are used worldwide for healing skin wounds. This study aimed to develop and compare two creams containing a leaf aqueous extract of K. pinnata (KP; 6%) and its major flavonoid [quercetin 3-O-α-L-arabinopyranosyl-(1→2)-α-L-rhamnopyranoside] (0.15%). Both creams were topically evaluated in a ...

journal_title：Natural product research

authors： Coutinho MAS,Casanova LM,Nascimento LBDS,Leal D,Palmero C,Toma HK,Dos Santos EP,Nasciutti LE,Costa SS

更新日期：2020-09-14 00:00:00

abstract：:A new malyngamide (1) was isolated along with seven known compounds (2-8) from the marine cyanobacterium Moorea producens collected in Hawaii. Compound 1 represented the first reported malyngamide with a hydroxy moiety at C-7 of the characteristic fatty acid portion of the compound. Compound 1 showed cytotoxicity agai...

journal_title：Natural product research

authors： Jiang W,Zhou W,Othman R,Uchida H,Watanabe R,Suzuki T,Sakamoto B,Nagai H

更新日期：2018-01-01 00:00:00

abstract：:Three new aconitine-type C19-diterpenoid alkaloids, taipeinines A-C (1-3), were isolated from the roots of Aconitum taipaicum. The chemical structures of these three compounds were established as (1α,6α,8α,14α,16α)-20-ethyl-8,14-dihydroxy-1,6,16-trimethoxy-4-(methoxymethyl)-aconitane (1), (1α,6α,8α,14α,16β)-20-ethyl-8...

journal_title：Natural product research

authors： Guo ZJ,Xu Y,Zhang H,Li MY,Xi K

更新日期：2014-01-01 00:00:00

abstract：:A new 24-membered macrolide, 5'-epi-SPA-6952A (1), was isolated from the cultured broth of Streptomyces diastatochromogenes. The structure was elucidated by means of spectroscopic methods and comparing with literature data of the known 24-membered macrolide SPA-6952A. Compound 1 was found to show significant insectici...

journal_title：Natural product research

authors： Cao H,Liu W,Chang Y,Chen H,Zhang Y,Xu W,Tao L

更新日期：2019-03-01 00:00:00

abstract：:Two Streptomyces spp. strains responsible for potato common scab infections in Uruguay which do not produce diketopiperazines were identified through whole-genome sequencing, and the virulence factor produced by one of them was isolated and characterized. Phylogenetic analysis showed that both pathogenic strains can b...

journal_title：Natural product research

authors： Lapaz MI,López A,Huguet-Tapia JC,Pérez-Baldassari MF,Iglesias C,Loria R,Moyna G,Pianzzola MJ

更新日期：2019-10-01 00:00:00

abstract：:The serotonin (5-hydroxytryptamine) type 3 receptor is an important target in the control of digestive dysfunction such as anorexia and bulimia, and 5-HT3 receptor antagonists are effective against eating disorder and the early-phase chemotherapy and radiotherapy evoked vomiting. Our previous research of Valeriana jat...

journal_title：Natural product research

authors： Wang LX,Chen HL,Yan HL,Tang F,Zhang H,Li HX,Ye Q,Peng C,Tan YZ

更新日期：2019-09-10 00:00:00

abstract：:In our continuous search for cytotoxic compounds from the genus Zanthoxylum, chromatographic separation of the MeOH/CH2Cl2 (1:1) extract of Z. chalybeum yielded one new alkamide; 4-(isoprenyloxy)-3-methoxy-3,4-deoxymethylenedioxyfagaramide (1) and a known one; fagaramide (2). Similarly, from the MeOH/CH2Cl2 (1:1) extr...

journal_title：Natural product research

authors： Omosa LK,Mbogo GM,Korir E,Omole R,Seo EJ,Yenesew A,Heydenreich M,Midiwo JO,Efferth T

更新日期：2019-03-21 00:00:00

abstract：:Fructose feeding induces a rise in blood pressure in normal rats that is associated with insulin resistance, hyperinsulinemia, hyperglycaemia, hypercholesterolaemia and hypertriglyceridaemia. We have examined the effect of chronic administration of A-HRS (100 and 300 mg kg⁻¹; p.o.) isolated from Hibiscus rosa sinensis...

journal_title：Natural product research

authors： Mohan M,Khade B,Shinde A

更新日期：2012-01-01 00:00:00

abstract：:Two new xanthone derivatives, penixanthones A (1) and B (2), together with three known compounds, aspenicillide (3), 1,5-dihydroxy-3-methoxy-7-methyl-anthracene-9,10-dione (4) and 1,2-indandiol (5), were isolated from the ethyl acetate extract of a culture of the fungus Penicillium sp. SYFz-1, which was separated from...

journal_title：Natural product research

authors： Tao H,Wei X,Lin X,Zhou X,Dong J,Yang B

更新日期：2017-10-01 00:00:00

abstract：:The anti-enteroviral activity of three stilbenoids isolated from the leaves of Macaranga barteri was investigated using the cytopathic effect reduction assay. The stilbenes were inactive against echovirus E13 but showed activity against echoviruses E7 and E19. In particular, vedelianin (2), schweinfurthin G (3) and ma...

journal_title：Natural product research

authors： Segun PA,Ogbole OO,Akinleye TE,Faleye TOC,Adeniji AJ

更新日期：2019-07-25 00:00:00

abstract：:A new rare lumazine peptide, penilumamide E (1), together with 13 known compounds (2-14) were isolated from the fungus Aspergillus terreus. Their structures were identified by spectroscopic techniques. The relative configuration of 1 was confirmed by single-crystal X-ray diffraction analysis. Compound 10 exhibited ant...

journal_title：Natural product research

authors： Chaiyosang B,Kanokmedhakul K,Boonmak J,Youngme S,Kukongviriyapan V,Soytong K,Kanokmedhakul S

更新日期：2016-01-01 00:00:00

abstract：:A new ent-kaurane diterpenoid, lophanthodin G (1) and one known abietanoid, 6alpha-hydroxyferruginol (2), were isolated from the leaves of Isodon lophanthoides var. geradianus. The structure of the new compound 1 was established using spectroscopic methods including extensive 1D and 2D NMR analysis. ...

journal_title：Natural product research

authors： Liu YH,Huang SX,Zhao QS,Ding JK,Goh NK,Sun HD,Chia TF,Tan SN,Chia LS

更新日期：2008-01-01 00:00:00

abstract：:The present study has been focused on the extraction of natural pigments from tomato industry waste. At first, different solvents and solvents mixture were compared to determine which one is the best for extracting carotenoids compounds from tomato by-products. A mixture of hexane and acetone gave the highest caroteno...

journal_title：Natural product research

authors： Baaka N,El Ksibi I,Mhenni MF

更新日期：2017-01-01 00:00:00

abstract：:The aim of the study was comparing the chemical composition of the essential oils from five varieties of lavender (Lavandula angustifolia L.), and its biological activity against two pathogenic bacteria, Staphylococcus aureus and Pseudomonas aeruginosa. In the comparison we included the following varieties: 'Munstead'...

journal_title：Natural product research

authors： Adaszyńska M,Swarcewicz M,Dzięcioł M,Dobrowolska A

更新日期：2013-01-01 00:00:00

abstract：:A new γ-pyrone derivative, acrepyrone A (1), and three known sorbicillinoids, trichodimerol (2), dihydrotrichodimerol (3) and tetrahydrotrichodimerol (4) were isolated from an endophytic fungus, Acremonium citrinum SS-g13, harboured in the roots of the Chinese medicinal plant Fructus mori. Their structures were determ...

journal_title：Natural product research

authors： Peng XP,Li G,Ji LX,Li YX,Lou HX

更新日期：2020-04-01 00:00:00

abstract：:Two new glycerol esters, (S)-2-hydroxy-3-(octanoyloxy)propyl tetracosanoate (1) and (S)-3-(((S)-11-acetoxy octadecanoyl)oxy)propane-1,2-diyl diacetate (2), and eight known compounds, docosanedioic acid (3), 2,5-dimethylnonadecane (4), lupeol (5), stigmasterol (6), β-sitosterol (7), heptadecanoic acid (8), hexanedioic ...

journal_title：Natural product research

authors： Forestrania RC,Anaya-Eugenio GD,Acuña UM,Ren Y,Elya B,de Blanco EC

更新日期：2020-06-12 00:00:00

abstract：:This study evaluates the presence, location and production source of tetrodotoxin (TTX) in two species of pufferfish, Diodon histrix and Arothron hispidus, common to Hawaiian waters. Organs from each fish were analysed for TTX and used to isolate bacteria for evaluation of possible TTX production. Comparative analyses...

journal_title：Natural product research

authors： Campbell S,Harada RM,DeFelice SV,Bienfang PK,Li QX

更新日期：2009-01-01 00:00:00

abstract：:Immuno-therapies are gaining more importance to treat certain forms of cancer. The goal of therapies is to enhance person's own IgG, IgA, IgM, IgD, IgE and macrophages to combat with neoplastic cells hence the effectiveness of the immune system. Since, early civilization mushrooms are considered as potent food as well...

journal_title：Natural product research

authors： Pandya U,Dhuldhaj U,Sahay NS

更新日期：2019-09-01 00:00:00

abstract：:Plant extracts and products have been used for centuries in traditional medicine; for most of them, in addition to the scant scientific credibility, the chemical composition and spectrum of activity are yet to be explored. To put forward this effort and to identify novel antimicrobial agents, the inhibitory activities...

journal_title：Natural product research

authors： Kumar P,Bhatt RP,Singh L,Sati OP,Khan A,Ahmad A

更新日期：2011-07-01 00:00:00

abstract：:Eight phenolic compounds, including two mixtures of two compounds, were isolated from the ethyl acetate extract of leaves and stems of Homalium brachybotrys. They were identified on the basis of spectroscopic data as quercetin-3-O-beta-glucopyranoside, luteolin-7-O-beta-glucopyranoside, 5,6-dihydro-6-beta-glucopyranos...

journal_title：Natural product research

authors： Mosaddik A,Forster PI,Waterman PG

更新日期：2007-11-01 00:00:00