Modulation of the 5-HT3A receptor current by desacylbaldrinal.

abstract：:One new neolignan glycoside, dolomiside A (1), together with 11 known phenylpropanoid glycosides were isolated from Dolomiaea souliei (Franch.) Shih. The structures of these isolates were determined by UV, CD, HR-ESI-TOFMS, 1D and 2D NMR analysis. ...

journal_title：Natural product research

authors： Yi M,Meng FC,Qu SY,Tao YY,Liao ZH,Chen M

更新日期：2020-04-01 00:00:00

abstract：:One new iridoid glycoside, 6',10-di-O-(4-hydroxybenzoyl) aucubin (1), together with ten known compounds, including five diterpenoids (2-6), two triterpene glucosides (7-8) and three methoxylated flavonoids (9-11) were isolated from the fruits of Vitex rotundifolia. Compounds (3, 4, 7, and 8) were reported for the firs...

journal_title：Natural product research

authors： Zhao YY,Guo L,Cao LJ,Zhang J,Yin ZQ

更新日期：2017-11-01 00:00:00

abstract：:In this study, the anti-tumour-promoting and thermal-induced protein denaturation inhibitory activities of β-sitosterol (1) and lupeol (2), isolated from Diospyros lotus L., were explored. Compound 1 showed a marked concentration-dependent inhibition against 12-O-tetradecanoylphorbol-13-acetate (20 ng/32 pmol)-induced...

journal_title：Natural product research

authors： Rauf A,Uddin G,Khan H,Raza M,Zafar M,Tokuda H

更新日期：2016-01-01 00:00:00

abstract：:A new furan derivative named 3-(5-oxo-2,5-dihydrofuran-3-yl) propanoic acid (1) was isolated for the first time. Its structure was elucidated by UV, IR, NMR, HR-ESI-MS and the single-crystal X-ray diffraction spectroscopic data. Meanwhile, the antifungal and antibacterial activities of compound 1 was tested, it exhibi...

journal_title：Natural product research

authors： Yang XF,Wang NN,Kang YF,Ma YM

更新日期：2019-10-01 00:00:00

abstract：:A new bisabolane-type sesquiterpenoid, turmerone Q (1), along with six known compounds (2-7), were isolated from the rhizomes of Curcuma longa L. The structural elucidation of the new compound was conducted using 1H NMR, 13C NMR, HSQC, HMBC and NOESY spectroscopic analyses. The absolute configuration of 1 was elucidat...

journal_title：Natural product research

authors： Yuan T,Zhang C,Qiu C,Xia G,Wang F,Lin B,Li H,Chen L

更新日期：2018-08-01 00:00:00

abstract：:The hexane and ethanol extracts from Himatanthus bracteatus (Apocynaceae) stems were evaluated for antiviral activity against Zika virus, yellow fever virus and dengue virus 2 and for cytotoxicity in Vero cells by MTT assay. The ethanol extract showed good antiviral activity against the three viruses with selective in...

journal_title：Natural product research

authors： da Silva ML,Stehmann JR,Serafim MSM,Vale VV,Gontijo DC,Brandão GC,Kroon EG,de Oliveira AB

更新日期：2019-11-20 00:00:00

abstract：:Essential oils from aerial parts of Senecio nutans, Senecio viridis, Tagetes terniflora and Aloysia gratissima were analysed by GC-MS and their antifungal activities were assayed on toxigenic Fusarium and Aspergillus species. Sabinene (27.6 ± 0.1%), α-phellandrene (15.7 ± 0.3%), o-cymene (9.6 ± 0.2%) and β-pinene (6.1...

journal_title：Natural product research

authors： Galvez CE,Jimenez CM,Gomez ALA,Lizarraga EF,Sampietro DA

更新日期：2020-05-01 00:00:00

abstract：:The content of total polyphenols, chlorogenic, caffeic (CaA) and ferulic acids, and rutin, was investigated in plant organs of three introgression lines (IL7-3, IL10-1 and IL12-4) of Solanum pennellii in Solanum lycopersicum cv M82 and compared with that of cropped parental. Such study aims to evidence factors associa...

journal_title：Natural product research

authors： Minutolo M,Amalfitano C,Evidente A,Frusciante L,Errico A

更新日期：2013-01-01 00:00:00

abstract：:One new havanensin-type limonoid (1) named trisinlin A with two known compounds (4E,8E)-2-[2'-hydroxyhexadecanoyl amino]-4,8-octadecadiene-1,3-diol (2), 9-octadecenoic acid-2',3'-dihydroxypropyl ester (3) were isolated from the roots of Trichilia sinensis. The structure of the new compound was unambiguously determined...

journal_title：Natural product research

authors： Liu SB,Chen HQ,Feng G,Guo ZK,Cai CH,Wang J,Mei WL,Dai HF

更新日期：2018-12-01 00:00:00

abstract：:From analysis by gas chromatography/mass spectrometry (GC/MS), the presence of either 2,4,5-tribromo-1H-imidazole (1) or 3,4,5-tribromo-1H-pyrazole (2) was tentatively identified in lipophilic extracts from the egg masses of three muricid molluscs. Synthesis of these compounds, followed by comparison of the GC retenti...

journal_title：Natural product research

authors： Benkendorff K,Pillai R,Bremner JB

更新日期：2004-10-01 00:00:00

abstract：:Peperomia obtusifolia is a herbaceous perennial plant native to the Americas reported as a traditional medicine to treat snake bites and as a skin cleanser. The bioassay-guided fractionation of crude extracts from aerial parts of P. obtusifolia against a panel of clinically important fungi and bacteria, showed that he...

journal_title：Natural product research

authors： Ruiz Mostacero N,Castelli MV,Cutró AC,Hollmann A,Batista JM Jr,Furlan M,Valles J,Fulgueira CL,López SN

更新日期：2019-06-14 00:00:00

abstract：:To search for possible cancer chemopreventive agents from natural sources, we performed primary screening of metabolites of Alternaria porri by examining their possible inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells. The et...

journal_title：Natural product research

authors： Horiuchi M,Tokuda H,Ohnishi K,Yamashita M,Nishino H,Maoka T

更新日期：2006-02-01 00:00:00

abstract：:A new polyoxygenated briarane-type diterpenoid, briarenol A (1), has been isolated from a gorgonian coral belonging to the genus Briareum. The structure, including the relative stereochemistry of briarane 1, was elucidated by the interpretation of spectral data. The configuration of 1 was further supported by molecula...

journal_title：Natural product research

authors： Sung PJ,Hu WP,Fang LS,Fan TY,Wang JJ

更新日期：2005-10-01 00:00:00

abstract：:Studies were made to increase the yield of piperine extraction using Naviglio Extractor® solid-liquid dynamic extractor (SLDE) from fruits of Piper longum. The effects of ratio w/v were investigated and optimised for the best method. The maximum yield of piperine (317.7 mg/g) from P. longum fruits was obtained in SLDE...

journal_title：Natural product research

authors： Gigliarelli G,Pagiotti R,Persia D,Marcotullio MC

更新日期：2017-01-01 00:00:00

abstract：:The phytochemical constituents in the aqueous methanolic leaf extract of Triclisia gilletii responsible for its nephroprotective potentials against ethane-1,2-diol induced nephrolithiasis as previously investigated in our laboratory were elucidated. The extract was prepared using 80% aqueous methanol in 72 h, Phytoche...

journal_title：Natural product research

authors： Olayeriju OS,Papetti A,Colombo R,Mannucci B,Olaleye MT,Akindahunsi AA

更新日期：2020-11-12 00:00:00

abstract：:As part of our search for compounds with cytotoxicity from endophytes of traditional Chinese medicines, two novel nor-sesquiterpenoids (1-2) with a new skeleton containing a tetrahydrofuran moiety were isolated form a rice medium of Fusarium tricinctum, an endophytic fungus isolated from the root of Ligusticum chuanxi...

journal_title：Natural product research

authors： Cao YM,Guo DL,Jin MY,Tan L,Yang TL,Deng F,Gu YC,Li XH,Cao ZX,Deng Y

更新日期：2020-01-24 00:00:00

abstract：:Platelet aggregation is fundamental to a wide range of physiological and pathological processes, including the induction of thrombosis and arteriosclerosis. Anti-platelet activity of a crude methanol extract and solvent fractions of Ashitaba roots (Angelica keiskei Koidz.) was evaluated using a turbidimetric method us...

journal_title：Natural product research

authors： Son DJ,Park YO,Yu C,Lee SE,Park YH

更新日期：2014-01-01 00:00:00

abstract：:Plants, in their life cycle, are usually exposed to various kinds of non-biological stresses including heavy metals. One of these heavy metals is nickel which affects many physiological processes of plants. Studies have shown that the changes in planting conditions can affect the qualitative and quantitative features ...

journal_title：Natural product research

authors： Arefifard M,Mahdieh M,Amirjani M

更新日期：2014-01-01 00:00:00

abstract：:Here is reported the anti Leishmania infantum activity of 48 hexane, CH2Cl2 and MeOH extracts from 16 macroalgae collected on the Iberian Coast. Seven hexane and CH2Cl2Cystoseira baccata, Cystoseira barbata, Cystoseira tamariscifolia, Cystoseira usneoides, Dictyota spiralis and Plocamium cartilagineum extracts were ac...

journal_title：Natural product research

authors： Bruno de Sousa C,Lago JHG,Macridachis J,Oliveira M,Brito L,Vizetto-Duarte C,Florindo C,Hendrickx S,Maes L,Morais T,Uemi M,Neto L,Dionísio L,Cortes S,Barreira L,Custódio L,Alberício F,Campino L,Varela J

更新日期：2019-06-01 00:00:00

abstract：:Pigeon Pea is a well-received traditional nutritious and medicinal plant in India since ancient times. The plant is identified for its impressive pharmacological activities like antimicrobial, anti-inflammatory, antitubercular, antioxidant, neuroprotective, antihypertensive, antihyperglycemic and anticancer properties...

journal_title：Natural product research

authors： Dinore JM,Farooqui M

更新日期：2020-11-23 00:00:00

abstract：:A new phenolic glycoside, 6-O-(4'-hydroxy-3',5'-dimethoxybenzoyl)-d-glucopyranose (4), and nine known compounds (1-3 and 5-10) were isolated from Juglans mandshurica Maxim. Compound structures were elucidated by NMR, HR-ESI-MS and acid hydrolysis. Compounds 5 and 6 are reported from this genus for the first time. Amon...

journal_title：Natural product research

authors： Yao D,Jin M,Zhang C,Luo J,Li R,Zheng M,Cui J,Li G

更新日期：2014-01-01 00:00:00

abstract：:Eleven compounds were isolated from the rhizomes of Paris polyphylla Smith var. yunnanensis. Their structures were elucidated on the basis of rigorous 1D and 2D NMR experiments as well as comparison with the literature data. To the best of our knowledge, compound 1 was only predicted by UPLC/Q-TOF MSE and the NMR spec...

journal_title：Natural product research

authors： Jing S,Wang Y,Li X,Man S,Gao W

更新日期：2017-03-01 00:00:00

abstract：:The present study has been focused on the extraction of natural pigments from tomato industry waste. At first, different solvents and solvents mixture were compared to determine which one is the best for extracting carotenoids compounds from tomato by-products. A mixture of hexane and acetone gave the highest caroteno...

journal_title：Natural product research

authors： Baaka N,El Ksibi I,Mhenni MF

更新日期：2017-01-01 00:00:00

abstract：:Three new flavonol glycosides (1-3), hippophins K-M, were isolated from the seed residue of Hippophae rhamnoides subsp. sinensis. The chemical structures of these three new compounds were identified by 1D, 2D NMR, mass spectroscopy and high resolution electrospray ionization mass spectrometry spectroscopic data and by...

journal_title：Natural product research

authors： Chen C,Gao W,Ou-Yang DW,Zhang J,Kong DY

更新日期：2014-01-01 00:00:00

abstract：:The chloroformic extract of the aerial parts of Ferula behboudiana (Umbelliferae) afforded four new polysulphane derivatives: 1-sec-butyl-2-[(E)-3-(methylthio)prop-1-enyl]disulphane (1), 1-sec-butyl-2-[(Z)-3-(methylthio)prop-1-enyl]disulphane (2), 1-[(E)-3-(methylthio)prop-1-enyl)-2-(1-(methylthio)propyl]disulphane (3...

journal_title：Natural product research

authors： Yousefi M,Mohammadi M,Habibi Z,Shafiee A

更新日期：2010-09-01 00:00:00

abstract：:Fruits of different Sorbus L. species have been traditionally used in food production and in the treatment of various ailments. Besides common antioxidant active phytochemicals such as ascorbic acid, tocopherols and carotenoids, fruits are rich in phenolic compounds that are of particular interest. In this study, prof...

journal_title：Natural product research

authors： Raudonis R,Raudonė L,Gaivelytė K,Viškelis P,Janulis V

更新日期：2014-01-01 00:00:00

abstract：:Penicillium polonicum MCCC3A00951 is a fungus with influenza neuraminidase (NA) inhibition activity derived from a sediment of the mangrove forest of Zhangjiangkou in Fujian province, China. Chemical investigation on an ethyl acetate extract of its fermentation led to the isolation of a new compound, 7-hydroxy-3,10-de...

journal_title：Natural product research

authors： Liu SZ,He FM,Bin YL,Li CF,Xie BY,Tang XX,Qiu YK

更新日期：2020-09-14 00:00:00

abstract：:Meliquercifolins A (1), and B (2), two new coumarins are bearing an acetophenone derivative were isolated from the leaves of Melicope quercifolia along with three known compounds, melicodenines E (3), F (4) and I (5). Structures of two new compounds were identified based on spectroscopic analyses (UV, HR-ESI-MS, 1 D a...

journal_title：Natural product research

authors： Saputri RD,Tjahjandarie TS,Tanjung M

更新日期：2019-07-22 00:00:00

abstract：:Chemical investigation of the mycelial extract of a mixed culture of two marine alga-derived fungal strains of the genus Aspergillus has yielded one new cyclotripeptide, psychrophilin E (1), the recently reported oxepin-containing alkaloids, protuboxepin A (2) and oxepinamide E (3), together with three other polyketid...

journal_title：Natural product research

authors： Ebada SS,Fischer T,Hamacher A,Du FY,Roth YO,Kassack MU,Wang BG,Roth EH

更新日期：2014-01-01 00:00:00

abstract：:Plant extracts and products have been used for centuries in traditional medicine; for most of them, in addition to the scant scientific credibility, the chemical composition and spectrum of activity are yet to be explored. To put forward this effort and to identify novel antimicrobial agents, the inhibitory activities...

journal_title：Natural product research

authors： Kumar P,Bhatt RP,Singh L,Sati OP,Khan A,Ahmad A

更新日期：2011-07-01 00:00:00