2,4,5-Tribromo-1H-imidazole in the egg masses of three muricid molluscs.

Abstract:

:From analysis by gas chromatography/mass spectrometry (GC/MS), the presence of either 2,4,5-tribromo-1H-imidazole (1) or 3,4,5-tribromo-1H-pyrazole (2) was tentatively identified in lipophilic extracts from the egg masses of three muricid molluscs. Synthesis of these compounds, followed by comparison of the GC retention times and fragmentation patterns from electron impact MS, with those of the natural products, indicated that it was 2,4,5-tribromo-1H-imidazole rather than the pyrazole. This imidazole is likely to be responsible for some of the antimicrobial activity observed in the egg extracts. This is the first report of this compound from a natural source.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Benkendorff K,Pillai R,Bremner JB

doi

10.1080/1478641031000620682

keywords:

subject

Has Abstract

pub_date

2004-10-01 00:00:00

pages

427-31

issue

5

eissn

1478-6419

issn

1478-6427

journal_volume

18

pub_type

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