Abstract:
:From analysis by gas chromatography/mass spectrometry (GC/MS), the presence of either 2,4,5-tribromo-1H-imidazole (1) or 3,4,5-tribromo-1H-pyrazole (2) was tentatively identified in lipophilic extracts from the egg masses of three muricid molluscs. Synthesis of these compounds, followed by comparison of the GC retention times and fragmentation patterns from electron impact MS, with those of the natural products, indicated that it was 2,4,5-tribromo-1H-imidazole rather than the pyrazole. This imidazole is likely to be responsible for some of the antimicrobial activity observed in the egg extracts. This is the first report of this compound from a natural source.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Benkendorff K,Pillai R,Bremner JBdoi
10.1080/1478641031000620682keywords:
subject
Has Abstractpub_date
2004-10-01 00:00:00pages
427-31issue
5eissn
1478-6419issn
1478-6427journal_volume
18pub_type
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