Abstract:
:Pigeon Pea is a well-received traditional nutritious and medicinal plant in India since ancient times. The plant is identified for its impressive pharmacological activities like antimicrobial, anti-inflammatory, antitubercular, antioxidant, neuroprotective, antihypertensive, antihyperglycemic and anticancer properties. The metabolites from Pigeon Pea leaves methanolic extract were identified using hyphenated instruments namely Gas Chromatography-Mass Spectroscopy (GC-MS) and Liquid Chromatography-Mass Spectroscopic (LC-MS) method. GC and LC chromatogram showed proper separation and presence of several bioactive compounds such as flavonoids, terpenoids, essential oils, alkaloids, and coumarins. LC-MS investigation reported the presence of Selidin (coumarin) and Tamarixetin (monomethoxyflavone) in the Pigeon Pea Leaves. The present investigations have demonstrated that methanolic extract of Pigeon Pea leaves exhibited impressive antibacterial activity against E. coli and antifungal activity against C. albicans with MIC values 50 μg/ml 250 μg/ml respectively. The extracts studied here have demonstrated to be a new remedial source used against diseases caused by these microorganisms.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Dinore JM,Farooqui Mdoi
10.1080/14786419.2020.1849197subject
Has Abstractpub_date
2020-11-23 00:00:00pages
1-5eissn
1478-6419issn
1478-6427pub_type
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