Two new nor-sesquiterpenoids from Fusarium tricinctum, an endophytic fungus isolated from Ligusticum chuanxiong.

abstract：:A new monoterpenoid indole alkaloid compound (1) and six known monoterpenoid indole alkaloids compounds (2-7) were isolated from the barks of Voacanga africana Staph. The structures were established by spectral analysis as ibogamine-16-carboxylic acid,17,20-didehydro-5,6-dioxo-10-methoxy-methyl ester (1), voacamine (2...

journal_title：Natural product research

authors： Chen HM,Yang YT,Li HX,Cao ZX,Dan XM,Mei L,Guo DL,Song CX,Dai Y,Hu J,Deng Y

更新日期：2016-01-01 00:00:00

abstract：:Triterpene saponins are throught to be potential anti-tumour agents in many cell types. This study aims to evaluate the cytotoxic activity and mechanism of a triterpene saponin, macranthoside B (MB), isolated from Lonicera macranthoides Hand.-Mazz. (Caprifoliaceae). A cell viability assay showed that MB inhibited cell...

journal_title：Natural product research

authors： Guan F,Shan Y,Zhao X,Zhang D,Wang M,Peng F,Xia B,Feng X

更新日期：2011-02-01 00:00:00

abstract：:Chemical investigation of the stems of Epigunum griffithianum led to the isolation and identification of a new triterpenoid saponin (1) and two known compounds (epigynosides A (2) and B (3)). These structures were elucidated by means of spectroscopic analysis (1D and 2D NMR, MS, UV, IR) as well as comparison with the ...

journal_title：Natural product research

authors： Wang Q,Li WY,Wang YD

更新日期：2020-05-01 00:00:00

abstract：:Pectins were isolated from bark, wood and pith of kenaf (Hibiscus cannabinus L.) variety Cuba108. Imidazole was used as extractant. The isolated pectins were studied by 13C nuclear magnetic resonance (13C-NMR) spectroscopy and diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS). From the spectroscopic...

journal_title：Natural product research

authors： Pappas CS,Tarantilis PA,Polissiou MG

更新日期：2003-06-01 00:00:00

abstract：:Lycopus europaeus L. leaves water extract (LEL) was subjected to phytochemical analysis, and evaluated for its antibacterial and antioxidant effects. Antibacterial activity testing was performed on Staphylococcus aureus clinical strains from catheter-related and skin infections by broth microdilution test. LEL showed ...

journal_title：Natural product research

authors： Fialová S,Slobodníková L,Veizerová L,Grančai D

更新日期：2015-01-01 00:00:00

abstract：:In the course of our efforts to search new secondary metabolites from marine-derived fungi, one new hexylitaconic acid derivative, 3-(5-methoxycarbonylpentyl)-4-methylfuran-2,5-dione (1), and two dimeric analogues asperwelwinates A and B (2 and 3), together with ten known compounds, asperitaconic acid C (4), kotanin (...

journal_title：Natural product research

authors： Han J,Yang N,Wei S,Jia J,Lin R,Li J,Bi H,Song F,Xu X

更新日期：2020-07-15 00:00:00

abstract：:The phytochemical constituents in the aqueous methanolic leaf extract of Triclisia gilletii responsible for its nephroprotective potentials against ethane-1,2-diol induced nephrolithiasis as previously investigated in our laboratory were elucidated. The extract was prepared using 80% aqueous methanol in 72 h, Phytoche...

journal_title：Natural product research

authors： Olayeriju OS,Papetti A,Colombo R,Mannucci B,Olaleye MT,Akindahunsi AA

更新日期：2020-11-12 00:00:00

abstract：:Two new eremophilenolides, ligushicins A (1) and B (2), and two known compounds including β-sitosterol and ursolic acid were isolated from Ligulariopsis shichuana. The structures of new compounds were established on the basis of 1D and 2D NMR data and HRESIMS data interpretation. The absolute configuration of new comp...

journal_title：Natural product research

authors： Wu H,Liu T,Lian Y,Wang W

更新日期：2019-05-01 00:00:00

abstract：:Three allylbenzenes from Asiasarum heterotropoides, methyleugenol (1), elemicin (2) and gamma-asaron (3) showed suppressive effects on umu gene expression of the SOS response in the Salmonella typhimurium OY1001/1A2 umu test against the mutagen 2-amino-3,4-dimethylimidazo[4,5-f ]quinoline (MeIQ). Gene expression was s...

journal_title：Natural product research

authors： Miyazawa M,Kohno G,Okuno Y,Oda Y

更新日期：2006-06-01 00:00:00

abstract：:The serotonin (5-hydroxytryptamine) type 3 receptor is an important target in the control of digestive dysfunction such as anorexia and bulimia, and 5-HT3 receptor antagonists are effective against eating disorder and the early-phase chemotherapy and radiotherapy evoked vomiting. Our previous research of Valeriana jat...

journal_title：Natural product research

authors： Wang LX,Chen HL,Yan HL,Tang F,Zhang H,Li HX,Ye Q,Peng C,Tan YZ

更新日期：2019-09-10 00:00:00

abstract：:Phytochemical investigation of the aerial parts of Eriope blanchetii and E. latifolia (Lamiaceae) yielded podophyllotoxin, as well as the aryltetralin lignans α- and β-peltatin and yatein. Oleanolic, ursolic and epikatonic acids were also isolated. This is the first occurrence of podophyllotoxin in the family. ...

journal_title：Natural product research

authors： Santos EO,Lima LS,David JM,Martins LC,Guedes ML,David JP

更新日期：2011-09-01 00:00:00

abstract：:The chemical composition of the essential oils isolated from the aerial parts of Anthemis arvensis L. subsp. arvensis, Anthemis cretica subsp. messanensis (Brullo) Giardina & Raimondo and from flowers and leaves of Anthemis cretica subsp. columnae (Ten.) Frezén were determinated by GC-FID and GC-MS analyses. Torreyol ...

journal_title：Natural product research

authors： Riccobono L,Maggio A,Bruno M,Spadaro V,Raimondo FM

更新日期：2017-12-01 00:00:00

abstract：:Four C-13, C-14 side chain modified 9(R)-hydroxy-1-deoxy-taxane analogues 15, 16, 19 and 22 were semi-synthesized from 1-deoxybaccatin VI. The in vitro antitumor activity of these compounds was evaluated against A549 and A2780 cell lines. The preliminary SAR analysis showed that introduction of oxygen-containing group...

journal_title：Natural product research

authors： Tang P,Lin HX,Yuan TH,Cui YM

更新日期：2019-12-01 00:00:00

abstract：:The aim of the present study was to study the effect of seeds of Asteracantha longifolia on the sexual behaviour of male albino rats. The ethanolic extract of seeds of A. longifolia was administered to groups of rats in 100, 150 and 200 mg kg⁻¹ doses for a period of 28 days, and the action compared with control rats. ...

journal_title：Natural product research

authors： Chauhan NS,Sharma V,Dixit VK

更新日期：2011-09-01 00:00:00

abstract：:A screening of Chinese medicinal herbs and wild plants for agrochemicals was carried out; the essential oil of Glycosmis lucida leaves was found to possess significant repellent activity against Tribolium castaneum and Liposcelis bostrychophila. It was found that the main components included elixene (19.81%), spathule...

journal_title：Natural product research

authors： Guo SS,Zhang WJ,Yang K,Liang JY,You CX,Wang CF,Li YP,Geng ZF,Deng ZW,Du SS

更新日期：2017-05-01 00:00:00

abstract：:A high performance liquid chromatography-time-of-flight-mass spectrometry (HPLC-TOF-MS) method was developed for analysing the chemical constituents in Hedyotis diffusa, which is widely used as a traditional Chinese medicine (TCM) in the field of cancer treatment. The compounds were identified either by comparing the ...

journal_title：Natural product research

authors： Wang X,Cheng W,Yao X,Guo X

更新日期：2012-01-01 00:00:00

abstract：:Two new flavans, named (2S)-2',4'-dihydroxy-7-methoxy-8-methylflavan (1) and (2S)-2'-hydroxy-4',7-dimethoxy-8-methylflavan (2) were isolated from the roots of Dianella ensifolia. Their structures were elucidated by extensive spectroscopic measurements and comparison with data reported in literatures. Compounds 1 and 2...

journal_title：Natural product research

authors： Tang BQ,Huang SS,Liang YE,Sun JB,Ma Y,Zeng B,Lee SM,Lu JL

更新日期：2017-07-01 00:00:00

abstract：:A new androstanoid metabolite, 4α-methyl-9α-methoxyandrosta-8,15-diene-3,17-dione (1), was isolated from a soil fungus Curvularia borreriae (Pleosporaceae) strain HS-FG-237. Its structure was determined by extensive spectroscopic and X-ray diffraction analyses. Compound 1 exhibited poor cytotoxicity toward HCT-116 cel...

journal_title：Natural product research

authors： Liu LF,Zhang H,Qi H,Wang XM,Wang JD,Tan GS

更新日期：2017-05-01 00:00:00

abstract：:A new propanamide analogue (1), along with one known alkaloid (2) and four known diketopiperazines (3-6), was isolated from a cultured broth of the actinomycete Streptomyces sp. Q24 that was obtained from a sample of mangrove soil. The structures of these isolates were characterised as 3-acetylamino-N-2-thienyl-propan...

journal_title：Natural product research

authors： Ye X,Chai W,Lian XY,Zhang Z

更新日期：2017-06-01 00:00:00

abstract：:Juniperus chinensis cv. Kaizuca has extensive pharmacological activities. The cone oils exhibited protein tyrosine phosphatase 1B inhibitory activity in vitro. The IC50 value was 4.49 ± 0.04 μg/mL. A total of 17 compounds were characterised from the cone oils by GC-MS. In order to explain the activity against protein ...

journal_title：Natural product research

authors： Fang C,Gu D,Yang J,Li M,Liu H,Yang Y

更新日期：2018-11-01 00:00:00

abstract：:Machaerium, in the family Fabaceae, predominantly is a genus of a Neotropical distribution of trees, shrubs, and lianas occurring from southern Mexico to Brazil and northern Argentina and as far as South America. Several Machaerium species are widely used in traditional medicine and are considered to have multiple med...

journal_title：Natural product research

authors： Amen YM,Marzouk AM,Zaghloul MG,Afifi MS

更新日期：2015-01-01 00:00:00

abstract：:One new anthraquinone, 1,8-dihydroxy-2-ethyl-3-methylanthraquinone (1), together with two known compounds octadecanoic acid (2) and cholest-4-en-3-one (3) was isolated from marine actinomycete Streptomyces sp. FX-58. The structure of 1 was elucidated on the basis of spectroscopic methods, especially, the 2D-NMR spectr...

journal_title：Natural product research

authors： Huang YF,Tian L,Fu HW,Hua HM,Pei YH

更新日期：2006-11-01 00:00:00

abstract：:Extracts from three Calophyllum species endemic to Sri Lanka were tested for antifungal and antioxidant activities. Of them, only the root methanol extract of Calophyllum thwaitesii showed activity, and the active extract on activity guided fractionation yielded four antifungal active and three inactive xanthones. Ant...

journal_title：Natural product research

authors： Dharmaratne HR,Napagoda MT,Tennakoon SB

更新日期：2009-01-01 00:00:00

abstract：:The ethanolic extract of the stems of Viburnum fordiae Hance showed insecticidal and α-glucosidase inhibitory activities and then was fractionated by bioactivity-guided fractionation to obtain a rare C13-norisoprenoid (1), together with a new phenolic glycoside (2), and seven known compounds, alangionoside C (3), pisu...

journal_title：Natural product research

authors： Shao JH,Chen J,Zhao CC,Shen J,Liu WY,Gu WY,Li KH

更新日期：2019-09-01 00:00:00

abstract：:From the fruit of Pandanus tectorius Parkinson ex Du Roi, one new dihydrofurocoumarin, named pandanusin A (1) and 15 known compounds, including one furanocoumarin (2), two coumarins (3, 4), four lignans (5-8), one neolignan (9), two flavonoids (10, 11), three phenolics (12-14), one monoglyceride (15) and one monosacch...

journal_title：Natural product research

authors： Nguyen TP,Le TD,Minh PN,Dat BT,Pham NK,Do TM,Nguyen DT,Mai TD

更新日期：2016-11-01 00:00:00

abstract：:Two new C13-norsesquiterpenes claulanterpene A (1) and B (2), together with two known sesquiterpenes (3-4), were isolated from methanol extract of the stem and leaf of Clausena lansium collected from Qingyuan county, Guangdong Province, China. Their structures were elucidated on the base of extensive spectroscopic ana...

journal_title：Natural product research

authors： Liu XY,Fu XX,Li YY,Xiong ZH,Li BT,Peng WW

更新日期：2020-03-25 00:00:00

abstract：:The composition and antibacterial activity of the essential oil of the aerial flowering parts of Nepeta hormozganica Jamzad have been studied. Analysis of the oil was conducted by GC-FID and GC-MS. Thirty-two components were characterized accounting for 99.4% of the total oil. Oxygenated monoterpenes (87.5%) were foun...

journal_title：Natural product research

authors： Sonboli A,Saadat MH,Arman M,Kanani MR

更新日期：2017-12-01 00:00:00

abstract：:Two new sesquiterpenoid glycosides as dihydrophaseic acid 4'-O-[6″-O-(4″'-hydroxy-3″', 5″'-dimethoxy) benzoyl)]-β-D-glucopyranoside (1) and dihydrophaseic acid 4'-O-[6″-O-(3″'-methoxy- 4″'-hydroxy) benzoyl)]-β-D-glucopyranoside (2), were isolated from the stems of Zanthoxylum armatum in the study. The compound 1 and 2...

journal_title：Natural product research

authors： Liu YL,Gao LL,Song TT,Guo T,Chang J

更新日期：2020-11-01 00:00:00

abstract：:A new resin glycoside, named calysolin XVIII (1), was isolated from the leaves, stems and roots of Calystegia soldanella Roem. et Schult. (Convolvulaceae). The structure of 1 was defined as 11S-jalapinolic acid 11-O-β-d-glucopyranosyl-(1 → 3)-O-(2-O-2S-methylbutyryl,4-O-3-hydroxy-2-methylenebutyryl)-α-l-rhamnopyranosy...

journal_title：Natural product research

authors： Ono M,Kanemaru Y,Yasuda S,Okawa M,Kinjo J,Miyashita H,Yokomizo K,Yoshimitsu H,Nohara T

更新日期：2017-11-01 00:00:00

abstract：:The aim of this study was to explore the extract/fractions and compounds of Diospyros lotus against various Gram-positive and Gram-negative bacteria strain. The results showed marked susceptibility of extract and its fractions against test pathogens. Among them, chloroform fraction was most dominant and effective agai...

journal_title：Natural product research

authors： Rauf A,Uddin G,Khan H,Arfan M,Siddiqui BS

更新日期：2016-01-01 00:00:00