One new anthraquinone from marine Streptomyces sp. FX-58.

abstract：:A new isopimarane-type diterpenoid, crolaevinoid A, along with four known analogues was isolated from the twigs and leaves of Croton laevigatus. The structures of the isolated compounds were established on the basis of NMR and MS spectroscopic analyses. The isolated compounds were examined the antibacterial activities...

journal_title：Natural product research

authors： Li MY,Han ZZ,Liu LF,Wu XZ,Huang WJ,Wang K,Yang F,Yuan CS

更新日期：2020-10-01 00:00:00

abstract：:A new protopine alkaloid, protomexicine and a new isoflavonoid, mexitin, together with 8-methoxydihydrosanguinarine, 13-oxoprotopine, rutin and quercetrin have been isolated from the aerial part of the methanolic extract of Argemone mexicana. The structures of these compounds have been established by various spectral ...

journal_title：Natural product research

authors： Singh S,Pandey VB,Singh TD

更新日期：2012-01-01 00:00:00

abstract：:The ethanolic extract of the leaves of Eriobotrya japonica exhibited inhibitory activity against phosphodiesterase-4D (PDE4D), which is a therapeutic target of inflammatory disease. Subsequent bioassay-guided fractionation led to the isolation of a new triterpene (1), together with seven known triterpenoids, methyl co...

journal_title：Natural product research

authors： Tan BX,Yang L,Huang YY,Chen YY,Peng GT,Yu S,Wu YN,Luo HB,He XX

更新日期：2017-12-01 00:00:00

abstract：:Epicatechin (EC) is the most effective compound in Euonymus alatus (Thunb.)Sieb, and possesses a series of benefits, including anti-inflammatory, antioxidant, antiobesity and anticancer effects. In this study, we investigated the protective effects of EC in Acetaminophen(N-acetyl-p-aminophenol, APAP)-induced acute liv...

journal_title：Natural product research

authors： Wu H,Xie Y,Xu Y,Hu Z,Wan X,Huang H,Huang D

更新日期：2020-03-01 00:00:00

abstract：:A new flavonol glycoside named Sabiapside A (1), along with four known compounds, quercetin-3-O-gentiobioside (2), camellianoside (3), isobariclisin-3-O- rutinoside (4), tsubakioside A (5), was isolated from Sabia parviflora. Their structures were elucidated by extensive spectroscopic analysis including MS, UV, IR and...

journal_title：Natural product research

authors： Sun Q,Pan G,Xu W,Lu X,Bai C,Liu M,Chen Y

更新日期：2019-10-29 00:00:00

abstract：:Lycopus europaeus L. leaves water extract (LEL) was subjected to phytochemical analysis, and evaluated for its antibacterial and antioxidant effects. Antibacterial activity testing was performed on Staphylococcus aureus clinical strains from catheter-related and skin infections by broth microdilution test. LEL showed ...

journal_title：Natural product research

authors： Fialová S,Slobodníková L,Veizerová L,Grančai D

更新日期：2015-01-01 00:00:00

abstract：:The aryltetralin lignans 6-methoxypodophyllotoxin, 5'-demethoxy-6-methoxypodophyllotoxin as well as the corresponding 8'-epimers 6-methoxypicropodophyllin, and 5'-demethoxy-6-methoxypicropodophyllin were isolated from suspension cultures of Linum cariense, and 4'-demethyl-6-methoxypodophyllotoxin together with 6-metho...

journal_title：Natural product research

authors： Konuklugil B,Ionkova I,Vasilev N,Schmidt TJ,Windhövel J,Fuss E,Alfermann AW

更新日期：2007-01-01 00:00:00

abstract：:Phytochemical investigation of Gymnocarpos decandrus roots lead to the isolation, characterization and evaluation of four compounds: the bis-coumarin daphnoretin, two biflavonoids: wikstrol A and wikstol B in addition to β-sitosterol glucoside. Their structures were established via spectroscopic data. The crude root e...

journal_title：Natural product research

authors： Fathy H

更新日期：2019-05-13 00:00:00

abstract：:In this article, an ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry method was developed to detect the chemical structures of proanthocyanidins (PAs) from seed coats of Schisandra chinensis. The cleavage pathways of the compounds were revealed. The structures of S. chinensis PAs, in...

journal_title：Natural product research

authors： Yan T,Hu GS,Wang AH,Hong Y,Jia JM

更新日期：2014-01-01 00:00:00

abstract：:The antioxidant, nitric oxide (NO) scavenging and malondialdehyde (MDA) scavenging activities of different Zataria multiflora (ZM) chemotype essential oils (EOs) were investigated. The main components are: ZM1 (carvacrol, p-cymene), ZM2 (carvacrol, p-cymene), ZM3 (carvacrol, p-cymene), ZM4 (linalool), ZM5 (carvacrol, ...

journal_title：Natural product research

authors： Karimian P,Kavoosi G,Saharkhiz MJ

更新日期：2012-01-01 00:00:00

abstract：:A new denudatine-type C20-diterpenoid alkaloid, pubesine (1), along with seven known diterpenoid alkaloids, altaconitine (2), 14-benzoylaconine (3), spicatine A (4), 14-benzoylaconine-8-palmitate (5), 14-O-acetylsenbusine A (6), senbusine A (7) and 14-acetylneoline (8) were isolated from the whole plant of Aconitum so...

journal_title：Natural product research

authors： Chen L,Shan L,Xu W,Zhang J,Huang S,Zhou X

更新日期：2017-03-01 00:00:00

abstract：:Salvia x jamensis J. Compton is a hybrid between Salvia greggii A. Gray and Salvia microphylla Kunt. In this study, we describe three hair types identified by Scanning Electron Microscopy. In the essential oil of the aerial parts of S. jamensis 56 different compounds were identified. The two main constituents were β-c...

journal_title：Natural product research

authors： Fraternale D,Albertini MC,Rudov A,Flamini G,Ricci D,Bisio A,Battistelli M,Accorsi A

更新日期：2013-01-01 00:00:00

abstract：:The chemical composition of the volatile concentrate prepared by supercritical CO(2) extraction of the needles of Pinus nigra Arnold ssp. laricio Poiret from Corsica was investigated using GC (RI), GC-MS and (13)C NMR spectroscopy. The major component was by far manoyl oxide (63%), a compound of potential interest for...

journal_title：Natural product research

authors： Duquesnoy E,Marongiu B,Castola V,Piras A,Porcedda S,Casanova J

更新日期：2007-07-20 00:00:00

abstract：:To obtain more accessible oxidative stress inhibitors, a series of novel spin-labelled derivatives of 3-hydroxybutanolide (2a-d, 3a-d) with the natural active compound (kinsenoside) as the lead compound were designed, synthesised from the nitroxide free radical piperidine (pyrroline) and the main structural unit of ki...

journal_title：Natural product research

authors： Liu Q,Liu ZL,Tian J,Shi W,Liu YQ

更新日期：2014-01-01 00:00:00

abstract：:Salvia apiana (white sage, Lamiaceae family) plant is native to southern California and parts of Mexico. Some Native American tribes local to this region consider S. apiana to be sacred and burn the leaves as incense for purification ceremonies. The plant has been used to treat sore throats, coughs, chest colds, upper...

journal_title：Natural product research

authors： Srivedavyasasri R,Hayes T,Ross SA

更新日期：2017-09-01 00:00:00

abstract：:Plants endue a key role against illnesses caused by oxidative stress. These attributes are frequently associated with polyphenolic compounds. However, presence and concentration of secondary metabolites are affected by abiotic factors. The in vitro culture techniques can solve these drawbacks. Peppers can be a suitabl...

journal_title：Natural product research

authors： Fidemann T,de Araujo Pereira GA,Bossard Nascimento L,Moraes MC,Bertão MR,da Silva RMG,Fernández Núñez EG

更新日期：2018-05-01 00:00:00

abstract：:The natural product lupeol 1 was isolated from aerial parts of Vernonia scorpioides with satisfactory yield, which made it viable to be used as starting material in semisynthetic approach. Ten lupeol derivatives 2-11 were prepared by classical procedures. Including, five new esters derivatives 7-11, which were obtaine...

journal_title：Natural product research

authors： Machado VR,Sandjo LP,Pinheiro GL,Moraes MH,Steindel M,Pizzolatti MG,Biavatti MW

更新日期：2018-02-01 00:00:00

abstract：:Physalins are seco-steroids with a variety of pharmacological activities already described. In this study the pharmacological properties of a standardized concentrated ethanolic extract from Physalis angulata (CEEPA), rich in physalins B, D, F and G, were studied in models of pain and inflammation in mice. Inflammator...

journal_title：Natural product research

authors： do Espírito Santo RF,Lima MDS,Juiz PJL,Opretzka LCF,Nogueira RC,Ribeiro IM,Tomassini TCB,Soares MBP,Villarreal CF

更新日期：2019-12-24 00:00:00

abstract：:Two new iridoids namely valerialloside A and valerianoside A (1 and 2) along with five known compounds (3-7) were isolated from the roots of Valeriana jatamansi Jones. The structure of new compounds were determined using 1D and 2D NMR including 1H-1H COSY, HSQC, HMBC and NOESY spectroscopic techniques. ...

journal_title：Natural product research

authors： Maurya AK,Kumar A,Agnihotri VK

更新日期：2020-12-09 00:00:00

abstract：:Accumulating evidences have shown the beneficial effects of natural products for Alzheimer's disease (AD) treatment. The present study was designed to investigate the neuroprotective effects of secondary metabolites of Galactomyces geotrichum (SMGG) on D-galactose induced AD mice. SMGG was extracted and its toxicologi...

journal_title：Natural product research

authors： Wang F,Wang F,Chen T

更新日期：2020-04-15 00:00:00

abstract：:In this study the antioxidant and cytotoxicity activity of the Adonidia merrillii fruits were investigated using different solvent polarities (methanol, ethyl acetate and water). The results showed that the total phenolic and flavonoid contents of the methanolic extract was higher compare with other extract with respe...

journal_title：Natural product research

authors： Vafaei A,Bin Mohamad J,Karimi E

更新日期：2019-09-01 00:00:00

abstract：:A study on essential oil fractions of the Western Balkan endemic Sideritis romana L. subsp. purpurea (Tal. ex Benth.) Heywood collected in Montenegro is reported. The 24-h systematic steam distillation extraction procedure was performed. The gas chromatographic/mass spectrometric (GC/MS) analysis of the fractions show...

journal_title：Natural product research

authors： Garzoli S,Božović M,Baldisserotto A,Andreotti E,Pepi F,Tadić V,Manfredini S,Ragno R

更新日期：2018-05-01 00:00:00

abstract：:32 medicinal plants that are unique to the Russian Pharmacopeia have 693 isolated natural products associated with them (an average of 21.66 compounds per plant). This is in contrast to the US Pharmacopeia plants that have delivered 2366 known natural products (an average of 42.25 compounds per plant). ...

journal_title：Natural product research

authors： Chupakhin E,Babich O,Prosekov A,Asyakina L,Gureev M,Krasavin M

更新日期：2020-02-21 00:00:00

abstract：:The aim of the present study was to evaluate the phenolic contents in capsule and root methanolic extracts of Euphorbia retusa followed by identification of phenolic on capsule extracts through high-performance liquid chromatography (HPLC- DAD) for the first time. Likewise, the antioxidant activity of both extracts wa...

journal_title：Natural product research

authors： Lahmadi S,Belhamra M,Karoune S,Imad K,Bensouici C,Kechebar MSA,Halis Y,Ksouri R

更新日期：2020-12-01 00:00:00

abstract：:A new highly oxygenated germacranolide, carcerlane A (1), together with four known highly oxygenated germacranolides (2-5), was isolated from an ethanol extract of the whole plant of Carpesium nepalense var. lanatum (C.B.Clarke) Kitam. The structures were determined by HRESIMS and extensive analysis of their spectrosc...

journal_title：Natural product research

authors： Yu YF,Li YQ,Wang RY,Liu X,Cui WB,Chen XH,Zhao CM,Qi FM,Zhang ZX,Fei DQ

更新日期：2020-10-22 00:00:00

abstract：:The present study was undertaken to investigate the antiproliferative action of isolated M1 (6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid) from Mucuna pruriens seeds using human hepatic carcinoma cell line (Huh-7 cells). Initially, docking studies was performed to find out the binding affinities of M...

journal_title：Natural product research

authors： Kumar P,Rawat A,Keshari AK,Singh AK,Maity S,De A,Samanta A,Saha S

更新日期：2016-01-01 00:00:00

abstract：:Jatropha mutabilis (Pohl) Baill is an endemic species of the Caatinga biome, little studied in terms of chemical composition. The objective of this work was to develop an analytical methodology to quantify vitexin in the ethanolic extract of J. mutabilis and to evaluate the expectorant and antitussive activities in mi...

journal_title：Natural product research

authors： Costa EC,Menezes PMN,Silva FS,Ribeiro LAA,Rolim LA,Araújo ECDC,Nunes XP

更新日期：2020-10-30 00:00:00

abstract：:The objective of this work was to produce and characterise nanoemulsions containing tucumã extract and to evaluate the performance of the nanostructure and the free compound regarding antitumor activity, cytotoxicity, and oxidative metabolism in NB4/APL cells. The nanoemulsions showed adequate physicochemical characte...

journal_title：Natural product research

authors： Copetti PM,Gündel SDS,de Oliveira PSB,Favarin FR,Ramos AP,Pintos FG,Pappis L,Gündel A,Machado AK,Ourique AF,Sagrillo MR

更新日期：2020-12-24 00:00:00

abstract：:Artemisia herba-alba is widely used in traditional medicines for the treatment of several diseases. From the aerial parts organic extract of A. herba-alba, two new compounds, 1,3,8-trihydroxyeudesm-4-en-7α,11βH-12,6α-olide (1) and 5-β-​D-​glucopyranosyloxy​-​7-methoxy-​6H-​benzopyran-​2-​one (2), respectively, togethe...

journal_title：Natural product research

authors： Mohamed TA,Abd El Aty AA,Shahat AA,Abdel-Azim NS,Shams KA,Elshamy AA,Ahmed MM,Youns SHH,El-Wassimy TM,El-Toumy SA,Hegazy MF

更新日期：2019-07-31 00:00:00

abstract：:Artemisia annua L. is an annual Eurasian desert-steppe plant. The composition of essential oils found in Artemisia annua from Russian (Buryatian) flora was analyzed in this work using gas chromatography mass-spectrometry method. Artemisia ketone, β-selinene, caryophyllene, caryophyllene oxide, germacrene D were the ma...

journal_title：Natural product research

authors： Zhigzhitzhapova SV,Dylenova EP,Gulyaev SM,Randalova TE,Taraskin VV,Tykheev ZA,Radnaeva LD

更新日期：2020-09-01 00:00:00