Abstract:
:Artemisia herba-alba is widely used in traditional medicines for the treatment of several diseases. From the aerial parts organic extract of A. herba-alba, two new compounds, 1,3,8-trihydroxyeudesm-4-en-7α,11βH-12,6α-olide (1) and 5-β-D-glucopyranosyloxy-7-methoxy-6H-benzopyran-2-one (2), respectively, together with five known metabolites: 3α,8β-dihydroxygermacr-4(15),9(10)-dien-7β,11αH,12,6α-olide (3), 1β,8α-dihydroxy-11α,13-dihydrobalchanin (4), 11-epiartapshin (5), tomenin (6) and benzoic acid, p-(β-D-glucopyranosyloxy)-methyl ester (7), were isolated and identified. The chemical structures were proven depending upon spectroscopic analysis, including 1 D/2D NMR as and ESI-MS. Compound 1 inhibited Gram-positive bacteria Bacillus subtilis and Staphylococcus aureus. Compounds 2 and 3 exhibited antibacterial activity against both gram-positive and gram-negative bacteria.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Mohamed TA,Abd El Aty AA,Shahat AA,Abdel-Azim NS,Shams KA,Elshamy AA,Ahmed MM,Youns SHH,El-Wassimy TM,El-Toumy SA,Hegazy MFdoi
10.1080/14786419.2019.1647430subject
Has Abstractpub_date
2019-07-31 00:00:00pages
1-9eissn
1478-6419issn
1478-6427pub_type
杂志文章abstract::Six new compounds, including three terpenoids (1-3) and three lignans (4-6), were isolated from the 95% EtOH extract of the twigs of Tripterygium hypoglaucum. Their structures were determined on the basis of extensive spectroscopic analysis. 9'-O-benzoyl-lariciresinol (4) showed weak cytotoxicity against HepG2/Adr cel...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1564297
更新日期:2020-07-01 00:00:00
abstract::Two new C-15 enolic acyl phragmalin-type limonoid orthoesters, chukvelutilide G (1) and chukrasine F (2), were isolated from the stem barks of Chukrasia tabularis var. velutina. Their structures were elucidated by their extensive high resolution-electrospray ionization mass spectrometry (HR-ESI-MS), one- and two-dimen...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.682995
更新日期:2013-04-01 00:00:00
abstract::Since the last decades, socio-economic changes have a key role on eating habits affecting the nutritional status and health of people, in particular children and adolescents. The aim of this study was to compare the diet of student population both normal weight and overweight and obese in order to understand their eat...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1402317
更新日期:2018-08-01 00:00:00
abstract::Coumarin (2H-1-benzopyran-2-one) is a phenolic compound derived from the shikimate pathway and synthesized by various medicinal and aromatic plants as parent molecule of a large group of secondary metabolites, namely coumarins. Its main utilization is as fixative in perfumes and flavour enhancer. Given its role as phy...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1660334
更新日期:2019-09-11 00:00:00
abstract::Bothrops jararacussu venom's (Bj2015) batch was biomonitored quarterly for one year to assess phospholipase A2 (PLA2) activity, immunogenicity, neurotoxicity, and myotoxicity. In silico models were applied to evaluate losses using decay model and recoveries by predictive trend analysis. Mice were immunized with Bj2015...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1446010
更新日期:2019-08-01 00:00:00
abstract::One new iridoid glycoside, 6',10-di-O-(4-hydroxybenzoyl) aucubin (1), together with ten known compounds, including five diterpenoids (2-6), two triterpene glucosides (7-8) and three methoxylated flavonoids (9-11) were isolated from the fruits of Vitex rotundifolia. Compounds (3, 4, 7, and 8) were reported for the firs...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1314284
更新日期:2017-11-01 00:00:00
abstract::Sahandinone (1), 12-deoxysalvipisone (2), miltirone (3), 7α-acetoxyroyleanone (4), and labda-7,14-dien-13-ol (5) were isolated from the roots of Salvia rhytidea Benth. (Lamiaceae). Their structures were elucidated by a combination of spectroscopic analyses including EIMS and NMR. The 13C NMR spectroscopic data were re...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1188096
更新日期:2017-02-01 00:00:00
abstract::Two new fatty acid esters of triterpenoids (1-2) together with eleven known compounds (3-13) were obtained after investigation of the CH2Cl2-MeOH (1:1) crude extract from the leaves of Schefflera barteri Harms. All these compounds (1-13) were isolated for the first time from this plant among which compounds 3, 4, 6 an...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1849199
更新日期:2020-11-18 00:00:00
abstract::The compositions of phenolic compounds in 10 cultivars of two mulberry species (Morus atropurpurea Roxb. and Morus alba Linn.) grown in four regions of China were analysed using HPLC-TOF-MS. Results showed that a total of 27 phenolic compounds were identified in these mulberry cultivars. The Taiwan cultivar from the J...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1274895
更新日期:2017-05-01 00:00:00
abstract::Comparison of an authentic sample of altertenuol with altenuisol obtained by total synthesis and analysis of nuclear magnetic resonance spectra unambiguously revealed that altertenuol and altenuisol are identical compounds. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.819509
更新日期:2013-01-01 00:00:00
abstract::Phytochemical investigation of Strychnos nitida has led to the isolation of three new racemic pyridocarbazole alkaloids, (±)-stritidas A-C (1-3) and three known monoterpenoid indole alkaloids (4-6). Compounds 2 and 3 represent the first examples of pyridocarbazole alkaloids featuring an N-2-hydroxyethyl moiety. Their ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1385016
更新日期:2018-07-01 00:00:00
abstract::The main purpose of this study was the characterisation of 'Serra da Lousã' heather honey by using novel statistical methodology, relevant principal component analysis, in order to assess the correlations between production year, locality and composition. Herein, we also report its chemical composition in terms of sug...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701825004
更新日期:2008-01-01 00:00:00
abstract::One new anthraquinone, 1,8-dihydroxy-2-ethyl-3-methylanthraquinone (1), together with two known compounds octadecanoic acid (2) and cholest-4-en-3-one (3) was isolated from marine actinomycete Streptomyces sp. FX-58. The structure of 1 was elucidated on the basis of spectroscopic methods, especially, the 2D-NMR spectr...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410600899142
更新日期:2006-11-01 00:00:00
abstract::Two new anthraquinone malonylglucosides polygonins A and B were isolated from Polygonum cuspidatum along with seven known compounds. The structures of 1 and 2 were elucidated based on their spectroscopic data. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.578072
更新日期:2012-01-01 00:00:00
abstract::A new butenolide derivative (1) featuring octyl substitution at γ-position, together with four known analogues (2-5) were isolated from marine-derived Streptomyces koyangensis SCSIO 5802. The structure of 1 was elucidated by HR-MS and NMR spectroscopic data analyses. The absolute configuration of the stereo centre in ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1686368
更新日期:2019-11-06 00:00:00
abstract::The anti-atherogenic potentials of total ginger (Zingiber officinale) extract (TGE) or curcuminoids extracted from turmeric (Curcuma longa), members of family Zingiberaceae, were compared in hypercholesterolaemia. Rabbits were fed either normal or atherogenic diet. The rabbits on atherogenic diet received treatments w...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.957699
更新日期:2015-01-01 00:00:00
abstract::One known bis-indole alkaloid-voacamine was isolated from Voacanga africana Stapf and Surface Plasmon Resonance imaging (SPRi) exprement showed that this alkaloid could be combine with Protein Tyrosine Phosphatase1B (PTP1B). Then the PTP1B activity inhibition experiment display that the compound showed an outstanding ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1480623
更新日期:2019-12-01 00:00:00
abstract::Ocimum is a genus of aromatic herbs, undershurbs or shrubs distributed in the tropical and warm temperate regions of the world. Larvicidal activity of essential oils and different extracts of O. sanctum, O. basilicum and O. gratissimum were compared on laboratory reared and field collected larvae of Culex quinquefasci...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.551755
更新日期:2011-12-01 00:00:00
abstract::Investigation on the leaves of Melicope bonwickii (F.Muell.) T.Hartley (Rutaceae) afforded a new 7-(2'-hydroxy-3'-chloroprenyloxy)-4-methoxyfuroquinoline (1) together with the known 7-(2',3'-epoxyprenyloxy)-4-methoxyfuroquinoline (2), evellerine (3) kokusaginine (4) and an amide aurantiamide acetate (5). Compounds 1 a...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410500462983
更新日期:2006-04-01 00:00:00
abstract::To date, despite extensive investigations, full understanding of the endocannabinoid system remains elusive; in particular, anandamide cellular uptake is a current controversial topic. An iodo-arylazido probe was synthesized from commercially available azelaic acid monomethyl ester, in order to shed light on the anand...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410500057015
更新日期:2005-06-01 00:00:00
abstract::Sasa coreana Nakai (SCN) is a medicinal plant commonly used against inflammation. However, the underlined mechanisms against skin inflammation is poorly understood. The present study investigated the effects of SCN leave extract on ear inflammation. To this aim, six-week-old male ICR mice was subjected to 12-O-tetrade...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1753053
更新日期:2020-04-14 00:00:00
abstract::Fermentation of (+)-androst-4-ene-3,17-dione (1) with Curvularia lunata for 10 days yielded five oxidative and reductive metabolites, androsta-1,4-diene-3,17-dione (2), 17beta-hydroxyandrosta-1,4-dien-3-one (3), 11alpha-hydroxyandrost-4-ene-3,17-dione (4), 11alpha,17beta-dihydroxyandrost-4-en-3-one (5) and 15alpha-hyd...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410310001620628
更新日期:2004-12-01 00:00:00
abstract::A novel monoterpenoid indole alkaloid, melognine (1) possessing an unprecedented skeleton with a 6/6/5/5/6/6 hexatomic rearranged ring system was isolated from the stems of Melodinus fusiformis. The structure with absolute configuration of 1 was established by extensive spectroscopic analyses and quantum ECD calculati...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1682579
更新日期:2019-11-01 00:00:00
abstract::Cyanamide (NH(2)CN) has recently been isolated as a plant growth inhibitor from Vicia villosa, which is the first discovery of cyanamide from natural sources. To reveal the presence of the biosynthesized cyanamide in plants, 3.4 mM potassium ((15)N)nitrate was administered to 15- to 35-day-old plants of V. villosa, fr...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410500143583
更新日期:2006-05-10 00:00:00
abstract::Designing propolis products for external use involves determining the optimal form of propolis for the introduction into dermatological pharmaceuticals and cosmetic preparations. As a potent ingredient, propolis oil extract from raw material harvested in Lithuania was analysed. The rheological characteristics, content...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.529440
更新日期:2011-09-01 00:00:00
abstract::A new C20-diterpenoid alkaloid carmichaedine (1) and six known alkaloids (2-7) were isolated from the lateral roots of Aconitum carmichaeli. Their structures were established on the basis of extensive spectroscopic analyses. Compound 1 exhibited potent antibacterial activity against Bacillus subtilis with minimum inhi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1219863
更新日期:2017-01-01 00:00:00
abstract::The aim of study was to compare the content of phenolic acids and flavonoids in two cultivars of Lavandula angustifolia: 'Blue River' and 'Ellagance Purple', including flowers and leafy stalks. Total phenolics and total flavonoids contents were determined by UV-Vis spectroscopy. The contents of total phenolics in leaf...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1320792
更新日期:2017-11-01 00:00:00
abstract::A new dehydrodigallic acid derivative (1), along with 19 known compounds, including 6 phenolic derivatives, 2 steroids and 11 triterpenoids were isolated from the ethanol extract of the root of Geum urbanum. Herein, there is the first report of steroid and triterpene in Geum urbanum. The purified metabolites were char...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1425844
更新日期:2018-11-01 00:00:00
abstract::A new triterpenoid glucoside, leuctriterpencoside (1), along with two known compounds (2-3) were isolated from Leucas zeylanica. The structure of the new compound was elucidated using comprehensive spectroscopic methods. Compound 1 showed significant inhibitory activity against α-glucosidase (IC50 value of 0.85 ± 0.12...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1566820
更新日期:2020-07-01 00:00:00
abstract::Two saponins: scrokoelziside A (1), scrokoelziside B (2), one iridoid glycoside, eurostoside (3), and two flavonoids: nepitrin (4) and homoplantaginin (5), were isolated from the leaves of Scrophularia ningpoensis for the first time. Moreover, eight known compounds: cane sugar (6), harpagide (7), aucubin (8), 6-O-meth...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802696247
更新日期:2009-01-01 00:00:00