New iridoids from the roots of Valeriana jatamansi Jones.

abstract：:Phorbol esters (PEs) are diterpenes present in Jatropha curcas L. seeds and have a myriad of biological activities. Since PEs are toxic, they are considered to be futile in Jatropha-based biodiesel production chain. In the present study, the extracted PEs from Jatropha oil were used as a starting material to synthesis...

journal_title：Natural product research

authors： Devappa RK,Malakar CC,Makkar HP,Becker K

更新日期：2013-01-01 00:00:00

abstract：:This study was focused on in vitro cytotoxicity screening of the raspberry seeds methanol extract towards a number of cancer cell lines of human origin. The tested extract at the preferred concentrations (IC50 <30 µg/mL) inhibited only the growth of the lung cancer A-549 cells (IC50 = 14.07 ± 0.96 µg/mL). At the same ...

journal_title：Natural product research

authors： Simonovic M,Kojic V,Jakimov D,Glumac M,Pejin B

更新日期：2019-09-17 00:00:00

abstract：:Three new flavonol glycosides (1-3), hippophins K-M, were isolated from the seed residue of Hippophae rhamnoides subsp. sinensis. The chemical structures of these three new compounds were identified by 1D, 2D NMR, mass spectroscopy and high resolution electrospray ionization mass spectrometry spectroscopic data and by...

journal_title：Natural product research

authors： Chen C,Gao W,Ou-Yang DW,Zhang J,Kong DY

更新日期：2014-01-01 00:00:00

abstract：:The purpose of this study is the determination of chemical composition and antioxidant activity of essential oils (EOs) from Saussurea costus (Falc.) Lipsch. Roots have been collected on December of the first plant year (IY) and in April, August and December of the third plant year (I, 6B, D7). A GC analysis was carri...

journal_title：Natural product research

authors： Benedetto C,D'Auria M,Mecca M,Prasad P,Singh P,Singh S,Sinisgalli C,Milella L

更新日期：2019-08-01 00:00:00

abstract：:The lipid peroxidation inhibitory activities of four hydroxyxanthones, isolated from the whole plant Swertia decussata, were evaluated for the first time. The most promising antioxidant among the xanthones, 1,7,8-trihydroxy-3-methoxyxanthone (swertianine, 4) was also tested for its scavenging potential against DPPH an...

journal_title：Natural product research

authors： Patro BS,Chintalwar GJ,Chattopadhyay S

更新日期：2005-06-01 00:00:00

abstract：:In this article, an ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry method was developed to detect the chemical structures of proanthocyanidins (PAs) from seed coats of Schisandra chinensis. The cleavage pathways of the compounds were revealed. The structures of S. chinensis PAs, in...

journal_title：Natural product research

authors： Yan T,Hu GS,Wang AH,Hong Y,Jia JM

更新日期：2014-01-01 00:00:00

abstract：:Two novel benzoquinones, uvarmicranones A (1) and B (2), along with 15 known compounds (3 - 17) were isolated from the stems of Uvaria micrantha (Annonaceae). Their structures were elucidated by analyses of NMR and high-resolution mass data. A plausible biosynthetic pathway of uvarmicranone A (1) via Diels-Alder cyclo...

journal_title：Natural product research

authors： Boonsombat J,Thongnest S,Kheawchaum S,Mahidol C,Ruchirawat S,Prawat H

更新日期：2020-09-22 00:00:00

abstract：:Two new sesquiterpenoid glycosides as dihydrophaseic acid 4'-O-[6″-O-(4″'-hydroxy-3″', 5″'-dimethoxy) benzoyl)]-β-D-glucopyranoside (1) and dihydrophaseic acid 4'-O-[6″-O-(3″'-methoxy- 4″'-hydroxy) benzoyl)]-β-D-glucopyranoside (2), were isolated from the stems of Zanthoxylum armatum in the study. The compound 1 and 2...

journal_title：Natural product research

authors： Liu YL,Gao LL,Song TT,Guo T,Chang J

更新日期：2020-11-01 00:00:00

abstract：:Three new neolignan derivatives (1-3), together with three known isolariciresinol derivatives (4-6) were isolated from Selaginella picta. Their structures were elucidated by spectroscopic methods (1D/2D NMR, HRESIMS and CD). All isolated compounds were assayed on the neuroprotective activity against the injury of HT-2...

journal_title：Natural product research

authors： Cheng F,Zou ZX,Xu PS,Zhang SH,Zhang Y,Yao CP,Xu KP,Tan GS

更新日期：2020-05-01 00:00:00

abstract：:Epicatechin (EC) is the most effective compound in Euonymus alatus (Thunb.)Sieb, and possesses a series of benefits, including anti-inflammatory, antioxidant, antiobesity and anticancer effects. In this study, we investigated the protective effects of EC in Acetaminophen(N-acetyl-p-aminophenol, APAP)-induced acute liv...

journal_title：Natural product research

authors： Wu H,Xie Y,Xu Y,Hu Z,Wan X,Huang H,Huang D

更新日期：2020-03-01 00:00:00

abstract：:A new 20-membered macrolide named as levantilide C was isolated from the Micromonospora strain FIM07-0019 recovered from shallow coastal waters near the island of Chiloe, Chile. The chemical structure of levantilide C was elucidated on the basis of one- and two-dimensional NMR analysis. Two known indole derivatives we...

journal_title：Natural product research

authors： Fei P,Chuan-Xi W,Yang X,Hong-Lei J,Lu-Jie C,Uribe P,Bull AT,Goodfellow M,Hong J,Yun-Yang L

更新日期：2013-08-01 00:00:00

abstract：:A new phenol glycoside, physanguloside A (1), was isolated from Physalis angulata together with four known compounds. We report herein, for the first time, the presence of compounds 2-5 in the genus Physalis. The structures of all the compounds were established by NMR, IR, UV and HRESIMS spectroscopic analyses, and co...

journal_title：Natural product research

authors： Sun CP,Nie XF,Kang N,Zhao F,Chen LX,Qiu F

更新日期：2017-05-01 00:00:00

abstract：:Here is reported the anti Leishmania infantum activity of 48 hexane, CH2Cl2 and MeOH extracts from 16 macroalgae collected on the Iberian Coast. Seven hexane and CH2Cl2Cystoseira baccata, Cystoseira barbata, Cystoseira tamariscifolia, Cystoseira usneoides, Dictyota spiralis and Plocamium cartilagineum extracts were ac...

journal_title：Natural product research

authors： Bruno de Sousa C,Lago JHG,Macridachis J,Oliveira M,Brito L,Vizetto-Duarte C,Florindo C,Hendrickx S,Maes L,Morais T,Uemi M,Neto L,Dionísio L,Cortes S,Barreira L,Custódio L,Alberício F,Campino L,Varela J

更新日期：2019-06-01 00:00:00

abstract：:Using a bioactivity-guided fractionation procedure, five cembranolides, 11-epi-sinulariolide acetate (1), 11-dehydrosinulariolide (2), sinulariolide (3), dihydrosinularin (4), and 3,4:8,11-bisepoxy-7-acetoxycembra-15(17)-en-1,12-olide (5), along with two nucleosides, 2'-deoxyadenosine and thymidine, were isolated from...

journal_title：Natural product research

authors： Hsieh PW,Chang FR,McPhail AT,Lee KH,Wu YC

更新日期：2003-12-01 00:00:00

abstract：:Two new flavans, named (2S)-2',4'-dihydroxy-7-methoxy-8-methylflavan (1) and (2S)-2'-hydroxy-4',7-dimethoxy-8-methylflavan (2) were isolated from the roots of Dianella ensifolia. Their structures were elucidated by extensive spectroscopic measurements and comparison with data reported in literatures. Compounds 1 and 2...

journal_title：Natural product research

authors： Tang BQ,Huang SS,Liang YE,Sun JB,Ma Y,Zeng B,Lee SM,Lu JL

更新日期：2017-07-01 00:00:00

abstract：:In this study, Box-Behnken Design was used to optimize the ultrasonic extraction of polysaccharides from quince peels (QPPs) by ascorbic acid and the effect of extraction temperature, extraction time and pH was evaluated. Under optimized conditions of temperature 90 °C, 60 min sonication time and pH = 3.26, the extrac...

journal_title：Natural product research

authors： Dammak MI,Mzoughi Z,Chakroun I,Mansour HB,Le Cerf D,Majdoub H

更新日期：2020-05-01 00:00:00

abstract：:Pressafonin A (1) and pressafonin B (2), two new Michelia monoterpenic esters, have been isolated from Michelia compressa (Maxim.) Sargent var. formosana Kanehira (Magnoliaceae), and their structures are determined on the basis of spectroscopic analysis. ...

journal_title：Natural product research

authors： Cheng MJ,Lo WL,Huang JC,Yeh YT,Hong ZL,Lu YC,Chang MS,Chen CY

更新日期：2010-04-01 00:00:00

abstract：:Salvia x jamensis J. Compton is a hybrid between Salvia greggii A. Gray and Salvia microphylla Kunt. In this study, we describe three hair types identified by Scanning Electron Microscopy. In the essential oil of the aerial parts of S. jamensis 56 different compounds were identified. The two main constituents were β-c...

journal_title：Natural product research

authors： Fraternale D,Albertini MC,Rudov A,Flamini G,Ricci D,Bisio A,Battistelli M,Accorsi A

更新日期：2013-01-01 00:00:00

abstract：:Eleven compounds were isolated from the rhizomes of Paris polyphylla Smith var. yunnanensis. Their structures were elucidated on the basis of rigorous 1D and 2D NMR experiments as well as comparison with the literature data. To the best of our knowledge, compound 1 was only predicted by UPLC/Q-TOF MSE and the NMR spec...

journal_title：Natural product research

authors： Jing S,Wang Y,Li X,Man S,Gao W

更新日期：2017-03-01 00:00:00

abstract：:This study was designed to investigate possible antidepressant-like effects of the extract prepared from the flowers of Hypericum montbretti Spach. (Guttiferae, Clusiaceae). Phytochemical constituents of the methanolic extract were analysed by HPLC method. The main flavonoid component was detected as rutin, and anothe...

journal_title：Natural product research

authors： Can OD,Ismail IB,Oztürk Y,Oztürk N,Potoğlu-Erkara I,Sagratini G,Ricciutelli M,Vittori S,Maggi F

更新日期：2011-09-01 00:00:00

abstract：:This article presents the very first phytochemical investigation on new species Tripleurospermum insularum Inceer & Hayırlıoglu-Ayaz. The volatile profile of odorous parts of the plant was analysed by GC/MS, and compounds were identified in headspace and essential oil obtained from aerial parts, representing 70.81% an...

journal_title：Natural product research

authors： Ćavar Zeljković S,Ayaz FA,Inceer H,Hayirlioglu-Ayaz S,Colak N

更新日期：2015-02-01 00:00:00

abstract：:Excessive accumulation of iron in the body can lead to organ injury. Some flavonoids which possess high affinity to iron can be used as iron chelators for curing iron overload diseases such as haemochromatosis. In this article, the effects of baicalin and quercetin on different mouse tissues (liver, kidney and heart) ...

journal_title：Natural product research

authors： Zhang Y,Gao Z,Liu J,Xu Z

更新日期：2011-07-01 00:00:00

abstract：:We report the first analysis in absolute, and in particular, concerning the phytochemical pattern, about an endemic Italian species, Ajuga tenorei C. Presl. The analysis, performed by means of techniques such as Column Chromatography and NMR spectroscopy and Mass spectrometry, led to the isolation and the identificati...

journal_title：Natural product research

authors： Frezza C,Venditti A,Di Cecco M,Ciaschetti G,Serafini M,Bianco A

更新日期：2017-01-01 00:00:00

abstract：:Commiphora wightii (Arn.) Bhandari, known as guggul, produces a medicinally important gum resin which is used extensively by Ayurvedic physicians to treat various ailments. However, most of the studies on C. wightii have been limited to its gum resin. Comprehensive metabolic profiling of leaves, stem and gum resin sam...

journal_title：Natural product research

authors： Bhatia A,Tripathi T,Singh S,Bisht H,Behl HM,Roy R,Sidhu OP

更新日期：2019-01-01 00:00:00

abstract：:A new highly oxygenated pseudoguaianolide, rudbeckolide (1), was isolated from Rudbeckia hirta L. flowers. The structure of this terpenoid lactone was established on the basis of extensive 1D and 2D NMR spectroscopic analyses. The compound exhibited strong 5-lipoxygenase inhibitory activity (84.9% inhibition at 10 μg/...

journal_title：Natural product research

authors： Michael BR,Gedara SR,Amer MM,Stevenson L,Ahmed AF

更新日期：2013-01-01 00:00:00

abstract：:Juniperus chinensis cv. Kaizuca has extensive pharmacological activities. The cone oils exhibited protein tyrosine phosphatase 1B inhibitory activity in vitro. The IC50 value was 4.49 ± 0.04 μg/mL. A total of 17 compounds were characterised from the cone oils by GC-MS. In order to explain the activity against protein ...

journal_title：Natural product research

authors： Fang C,Gu D,Yang J,Li M,Liu H,Yang Y

更新日期：2018-11-01 00:00:00

abstract：:Waste deriving from food and agro-industries is a growing problem in our modern society. In order to reduce food waste and its associated impacts over the environment and public health, innovative strategies for the conversion of food wastes in added value products are studied. Whey is one of the prominent waste deriv...

journal_title：Natural product research

authors： Gervasi T,Pellizzeri V,Benameur Q,Gervasi C,Santini A,Cicero N,Dugo G

更新日期：2018-07-01 00:00:00

abstract：:Oil content in sweet and bitter fennels was obtained 12.22% and 14.41%, respectively. The C(18:1 c6), C(18:2), C(18:1 c9) and C(16:0) acids corresponding to approximately 97% of total oil was recorded as principal fatty acids. The ratios of essential oil from sweet and bitter fennels were found similar (average 3.00%)...

journal_title：Natural product research

authors： Coşge B,Kiralan M,Gürbüz B

更新日期：2008-01-01 00:00:00

abstract：:This work reports the phytochemical profile and insecticidal properties of Perovskia artemisioides Boiss essential oil (PAEO) collected in Baluchestan, Iran. Totally, twenty-six substances were identified with 1,8-cineole (25.81%), geranyl acetate (13.00%) and linalool (10.21%) as dominant chemical metabolites by GC-M...

journal_title：Natural product research

authors： Sadeghi Z,Alizadeh Z,Khorrami F,Norouzi S,Moridi Farimani M

更新日期：2020-08-26 00:00:00

abstract：:Chronic administration of myricetin (100 and 300 mg kg⁻¹, p.o., for 4 weeks) isolated from Vitis vinifera (Vitaceae) ameliorated hypertension and oxidative stress induced by deoxycorticosterone acetate (DOCA)-salt in rats. Myricetin treatment reduced systolic blood pressure, vascular reactivity changes and reversed th...

journal_title：Natural product research

authors： Borde P,Mohan M,Kasture S

更新日期：2011-09-01 00:00:00