Chemical and biological evaluation of essential oil from Saussurea costus (Falc.) Lipsch. from Garhwal Himalaya collected at different harvesting periods.

abstract：:Three new (1-3) and 17 known (4-20) iridoid and secoiridoid glycosides were isolated from a methanol extract of the rhizomes and roots of Gentiana scabra. Their chemical structures were elucidated from 1D and 2D NMR, IR absorption, and HR-ESI-MS spectra, as well as comparisons of these data with reported values. The e...

journal_title：Natural product research

authors： Li W,Zhou W,Kim S,Koo JE,Kim Y,Koh YS,Shim SH,Ma JY,Kim YH

更新日期：2015-01-01 00:00:00

abstract：:The monoterpenoid fractions of three endemic Galium ssp. (Rubiaceae) from Sardinia Island were examined and compared with the iridoidic pattern yet known in Galium species. This comparison evidenced theirs endemic characters. In particular, in G.corsicum and in G. glaucophyllum loganic acid was isolated and identified...

journal_title：Natural product research

authors： Serrilli AM,Ramunno A,Amicucci F,Chicarella V,Santoni S,Ballero M,Serafini M,Bianco A

更新日期：2008-05-10 00:00:00

abstract：:Plumieride (PLU), an iridoid isolated from Allamanda cathartica flowers, has been studied by our research group due to its anti-inflammatory potential, antidepressant-like and anxiolytic-like effects. This research investigated the involvement of GABAergic and monoaminergic systems in the anxiolytic-like effect elicit...

journal_title：Natural product research

authors： Dalmagro AP,Camargo A,Zimath PL,Bonomini TJ,Zeni ALB,Malheiros A,de Souza MM

更新日期：2020-03-11 00:00:00

abstract：:The anti-enteroviral activity of three stilbenoids isolated from the leaves of Macaranga barteri was investigated using the cytopathic effect reduction assay. The stilbenes were inactive against echovirus E13 but showed activity against echoviruses E7 and E19. In particular, vedelianin (2), schweinfurthin G (3) and ma...

journal_title：Natural product research

authors： Segun PA,Ogbole OO,Akinleye TE,Faleye TOC,Adeniji AJ

更新日期：2019-07-25 00:00:00

abstract：:A new polycyclic polyprenylated acylphloroglucinol (1), nujiangefolin D, together with five known analogues (2-6), were isolated from the fruits of Garcinia nujiangensis. Compound 1 was screened by the LC-MS and LC-PDA. The structure of 1 was elucidated on the basis of extensive spectroscopic techniques including 1 D ...

journal_title：Natural product research

authors： Tang Z,Lu L,Zhou X,Shen J,Song W,Tang Y,Xia Z

更新日期：2020-09-01 00:00:00

abstract：:Chronic neuroinflammation is a key component of many neurodegenerative disorders. Chronic activation of this process produces pro-inflammatory cytokines, prostaglandins and reactive oxygen species that induce brain injury and neuronal dysfunction. Agave species contain saponins, compounds with anti-inflammatory activi...

journal_title：Natural product research

authors： Herrera-Ruiz M,Jiménez-Ferrer E,Tortoriello J,Zamilpa A,Alegría-Herrera E,Jiménez-Aparicio AR,Arenas-Ocampo ML,Martínez-Duncker I,Monterrosas-Brisson N

更新日期：2019-05-14 00:00:00

abstract：:Two new eremophilenolides, ligushicins A (1) and B (2), and two known compounds including β-sitosterol and ursolic acid were isolated from Ligulariopsis shichuana. The structures of new compounds were established on the basis of 1D and 2D NMR data and HRESIMS data interpretation. The absolute configuration of new comp...

journal_title：Natural product research

authors： Wu H,Liu T,Lian Y,Wang W

更新日期：2019-05-01 00:00:00

abstract：:The content of total polyphenols, chlorogenic, caffeic (CaA) and ferulic acids, and rutin, was investigated in plant organs of three introgression lines (IL7-3, IL10-1 and IL12-4) of Solanum pennellii in Solanum lycopersicum cv M82 and compared with that of cropped parental. Such study aims to evidence factors associa...

journal_title：Natural product research

authors： Minutolo M,Amalfitano C,Evidente A,Frusciante L,Errico A

更新日期：2013-01-01 00:00:00

abstract：:This work reports the results and the comparison concerning the chemical and biomolecular analyses and the antifungal activity of three wild Pistacia species (Anacardiaceae) from Sardinia. Volatile oils from leaves and twigs of Pistacia x saportae, Pistacia lentiscus and Pistacia terebinthus were characterised using G...

journal_title：Natural product research

authors： Marengo A,Piras A,Falconieri D,Porcedda S,Caboni P,Cortis P,Foddis C,Loi C,Gonçalves MJ,Salgueiro L,Maxia A

更新日期：2018-12-01 00:00:00

abstract：:In order to identify genes related to Taxol biosynthesis, the mRNA differential display method was employed to compare mRNA populations from suspension cultured Taxus chinensis cells before and after beginning to produce Taxol. From a total display of about 4000 PCR products, 104 were derived from cells during the Tax...

journal_title：Natural product research

authors： Hu G,Fan T,Mei X

更新日期：2004-08-01 00:00:00

abstract：:This study aimed at evaluating the impact of environmental factors on the accumulation of various components in Hedera helix L. folium collected from different European countries. The obtained results of studied samples showed that the antioxidant capacities were in the range of 0.027 to 0.688 mg/g. Contents of active...

journal_title：Natural product research

authors： Bezruk I,Materiienko A,Gubar S,Proskurina K,Budanova L,Ivanauskas L,Georgiyants V

更新日期：2020-11-04 00:00:00

abstract：:Oldenlandia umbellata L., commonly known as 'chay root', belongs to the family Rubiaceae and is one of the unexplored dye-yielding plants. The roots from this plant are the sources of red dye. Extraction protocol and dye characterisation have not been completely studied so far in this plant. Hence, in this article we ...

journal_title：Natural product research

authors： Ramamoorthy S,Mudgal G,Rajesh D,Nawaz Khan F,Vijayakumar V,Rajasekaran C

更新日期：2009-01-01 00:00:00

abstract：:To date, despite extensive investigations, full understanding of the endocannabinoid system remains elusive; in particular, anandamide cellular uptake is a current controversial topic. An iodo-arylazido probe was synthesized from commercially available azelaic acid monomethyl ester, in order to shed light on the anand...

journal_title：Natural product research

authors： Balas L,Hellal M,Rossi JC,Durand T

更新日期：2005-06-01 00:00:00

abstract：:Neuroprotection under conditions of oxygen stress of two C21 steroidal glycosides, cynsaccatol Q (1) and saccatol K (2), isolated from Cynanchum auriculatum Royle ex Wight, and their potential mechanisms were studied using the model of H2O2-induced damage on PC12 cells in this paper. Experiments showed that compounds ...

journal_title：Natural product research

authors： Zhang M,Wang D,Li B

更新日期：2019-07-02 00:00:00

abstract：:The first chemotaxonomic study based on volatile components of Porella viridissima (Mitt.) Grolle is reported. The GC-MS analysis of ether extract was performed; ten santalane and five pinguisane-type sesquiterpenes were identified together with perrottetianal A as major diterpene. Most of detected santalane-type sesq...

journal_title：Natural product research

authors： Métoyer B,Lebouvier N,Hnawia E,Thouvenot L,Wang F,Harinantenaina Rakotondraibe L,Raharivelomanana P,Asakawa Y,Nour M

更新日期：2019-08-23 00:00:00

abstract：:Two new lupene-type triterpenoids, 3β,6β-dihydroxylup-20(29)-en-28-oic acid β-glucopyranosyl ester (1) and 2α-acetoxyl-3β,6β-dihydroxylup-20(29)-en-28-oic acid β-glucopyranosyl ester (2), along with 18 known compounds, were isolated from Liquidambar formosana. The structures were elucidated on the basis of spectroscop...

journal_title：Natural product research

authors： Yu J,Liu S,Xuan L

更新日期：2012-01-01 00:00:00

abstract：:Two Streptomyces spp. strains responsible for potato common scab infections in Uruguay which do not produce diketopiperazines were identified through whole-genome sequencing, and the virulence factor produced by one of them was isolated and characterized. Phylogenetic analysis showed that both pathogenic strains can b...

journal_title：Natural product research

authors： Lapaz MI,López A,Huguet-Tapia JC,Pérez-Baldassari MF,Iglesias C,Loria R,Moyna G,Pianzzola MJ

更新日期：2019-10-01 00:00:00

abstract：:One new tirucallane-type nortriterpenoid Nortirucallane A (1), together with Chrysoeriol (2) and Isorhamnetin (3), was isolated from the methylene chloride part of Lonicerae japonicae flos. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. Compound 3 was isolated from the g...

journal_title：Natural product research

authors： Wang X,Zhang J,Li YQ,Du BX,Sun QH,Cao YJ,Jiang HQ,Liu YH,Zhou HL,Rong R

更新日期：2017-10-01 00:00:00

abstract：:Oil content in sweet and bitter fennels was obtained 12.22% and 14.41%, respectively. The C(18:1 c6), C(18:2), C(18:1 c9) and C(16:0) acids corresponding to approximately 97% of total oil was recorded as principal fatty acids. The ratios of essential oil from sweet and bitter fennels were found similar (average 3.00%)...

journal_title：Natural product research

authors： Coşge B,Kiralan M,Gürbüz B

更新日期：2008-01-01 00:00:00

abstract：:The chemical composition of the essential oil of Kurzamra pulchella (Lamiaceae) was determined. Twelve compounds were identified, with isomenthone (60.6%) and pulegone (37.1%) predominating. Chemotaxonomical considerations were discussed. ...

journal_title：Natural product research

authors： Echeverría J,Niemeyer HM

更新日期：2017-01-01 00:00:00

abstract：:The cytotoxicity of six ent-kaurene diterpenoids isolated from the leaves of Isodon japonica (Burm.f.) Hara var. galaucocalyx (maxin) Hara was evaluated against three human tumour HepG2, GLC-82 and HL-60 cell lines through SRB assay, and their DNA damage potential (against HepG2 cell line) was assessed by comet assay....

journal_title：Natural product research

authors： Ding L,Zhou Q,Wang L,Wang W,Zhang S,Liu B

更新日期：2011-09-01 00:00:00

abstract：:A new pterocarpan, named velucarpin D (1), along with nine known pterocarpans (2-10) were isolated from the stems of Dalbergia velutina. Their structures were determined by spectroscopic analysis. All isolated compounds were evaluated for their cytotoxicity against five human cancer cell lines (KB, HeLa S-3, MCF-7, He...

journal_title：Natural product research

authors： Kaennakam S,Sukandar ER,Hongnak S,Rassamee K,Siripong P,Tip-Pyang S

更新日期：2020-04-05 00:00:00

abstract：:Six new compounds, including three terpenoids (1-3) and three lignans (4-6), were isolated from the 95% EtOH extract of the twigs of Tripterygium hypoglaucum. Their structures were determined on the basis of extensive spectroscopic analysis. 9'-O-benzoyl-lariciresinol (4) showed weak cytotoxicity against HepG2/Adr cel...

journal_title：Natural product research

authors： Zheng H,Wang L,Yang T,Liu D,Li HM,Chen XQ,Li RT

更新日期：2020-07-01 00:00:00

abstract：:The aerial portions of Cynara scolymus commonly have been eaten as vegetables or functional foods by the people lived in Mediterranean region. In preliminary antioxidant screening, the rhizome portions (CSR) of this species showed better potential than leaves ones. However, neither phytochemical nor pharmacology studi...

journal_title：Natural product research

authors： Lee CL,Liao KC,Chen CC,Lin YA,Wu TY,Jhan YL,Chen CJ,Yang JC,Wu YC

更新日期：2019-07-30 00:00:00

abstract：:In this study, the ethanol extract of Momordica dioica fruit extract (200 mg kg(-1)) was studied for nephroprotective and curative activities. Chloroform, ethyl acetate, ethanol and aqueous extracts were prepared. In vitro antioxidant activity was made the basis for the selection of the ethanol extract for further stu...

journal_title：Natural product research

authors： Jain A,Singhai AK

更新日期：2010-05-01 00:00:00

abstract：:The comet assay-guided fractionation of the twigs of Manglietia hookeri resulted in the isolation of three sesquiterpene-neolignans, including a new one 5-allyl-2-(4-allyl-phenoxy)-3-[7-(1-hydroxy-1-methyl-ethyl)-1, 4a-dimethyl-decahydro-naphthalen-1-yloxy]-phenol (1), and eudesobovatol A (2) and eudesobovatol B (3), ...

journal_title：Natural product research

authors： Hu X,Sui X,Wang Y,Wang W,Wu H,Zhang F,Tan Y,Zhang F

更新日期：2016-07-01 00:00:00

abstract：:A phytochemical reinvestigation of the whole plant of Euphorbia segetalis yielded five tetracyclic triterpenes: 3beta-hydroxy-cycloart-25-en-24-one (1), cycloart-25-ene-3beta,24-diol (2), cycloart-23-ene-3beta,25-diol (3), lanosta-7,9(11),24-trien-3beta-ol (4) and lanosta-7,9(11),24(31)-trien-3beta-ol (5). beta-acetox...

journal_title：Natural product research

authors： Madureira AM,Ascenso JR,Valdeira L,Duarte A,Frade JP,Freitas G,Ferreira MJ

更新日期：2003-10-01 00:00:00

abstract：:The study examined the radioprotective activity of an aqueous extract from Pleurotus ostreatus mycelium administered to Balb/c mice. Male mice were whole-body irradiated on day 0 ((60)Co, at 0.43 Gy/min) and divided into two groups. The extract was administered intraperitoneally to one group (100 mg/kg) on days - 10 t...

journal_title：Natural product research

authors： Llauradó G,Morris HJ,Tamayo V,Lebeque Y,Beltrán Y,Marcos J,Moukha S,Creppy EE,Bermúdez RC

更新日期：2015-01-01 00:00:00

abstract：:A new triterpenoid saponin, silenoviscoside F (1), was isolated from the roots of Silene viscidula, together with three known saponins, dianchinenoside D (2), sinocrassuloside I (3) and sinocrassuloside II (4). The structure of compound 1 was elucidated by spectroscopic data, GC-MS and chemical methods. The structures...

journal_title：Natural product research

authors： Xu W,Fang J,Zhu Z,Wu J,Li Y

更新日期：2012-11-01 00:00:00

abstract：:Two new glycerol esters, (S)-2-hydroxy-3-(octanoyloxy)propyl tetracosanoate (1) and (S)-3-(((S)-11-acetoxy octadecanoyl)oxy)propane-1,2-diyl diacetate (2), and eight known compounds, docosanedioic acid (3), 2,5-dimethylnonadecane (4), lupeol (5), stigmasterol (6), β-sitosterol (7), heptadecanoic acid (8), hexanedioic ...

journal_title：Natural product research

authors： Forestrania RC,Anaya-Eugenio GD,Acuña UM,Ren Y,Elya B,de Blanco EC

更新日期：2020-06-12 00:00:00