Abstract:
:A new pterocarpan, named velucarpin D (1), along with nine known pterocarpans (2-10) were isolated from the stems of Dalbergia velutina. Their structures were determined by spectroscopic analysis. All isolated compounds were evaluated for their cytotoxicity against five human cancer cell lines (KB, HeLa S-3, MCF-7, Hep G2, and HT-29). Compound 2 showed potent cytotoxicity against all the five human cancer cell lines with IC50 values in the range of 4.74-8.46 µM. In addition, compounds 1, 3, 4, 5 and 9 showed moderate cytotoxicity against both KB and HeLa S-3 cells with IC50 values in the range of 14.23-29.35 µM.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Kaennakam S,Sukandar ER,Hongnak S,Rassamee K,Siripong P,Tip-Pyang Sdoi
10.1080/14786419.2020.1749613subject
Has Abstractpub_date
2020-04-05 00:00:00pages
1-6eissn
1478-6419issn
1478-6427pub_type
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