A new oleanolic-type triterpene glycoside from Anchusa italica.

Abstract:

:A new oleanolic-type triterpene glycoside, (3β,21β)-21-[(β-d-glucopyranosyl-(1→2)-β-d-glucopyranosyl)oxy]-3-hydroxyolean-12-en-28-oic acid (1), together with five analogues, oleanazuroside 1 (2), oleanazuroside 2 (3), 24-hydroxytormentic acid ester glucoside (4), 24-epi-pinfaensin (5), and oleanolic acid 3-O-α-l-arabinoside (6) were isolated from the n-butyl alcohol extract of Anchusa italica. Their structures were determined spectroscopically and compared with previously reported spectral data. Compounds 3-4 and 6 were evaluated for their cytotoxic activities against five human cancer cell lines, but only compound 6 showed moderate cytotoxicity.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Chen KK,Xie ZJ,Dai W,Wang Q

doi

10.1080/14786419.2016.1258557

subject

Has Abstract

pub_date

2017-04-01 00:00:00

pages

959-965

issue

8

eissn

1478-6419

issn

1478-6427

journal_volume

31

pub_type

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