Abstract:
:Chromatographic fractionation of the chloroform extracts from the stem bark and stems of Guettarda grazielae resulted in the isolation of a new iridoid (guettardodiol, 1) and the secoiridoid sarracenin (2), described for the first time in this genus. The structural elucidation of these compounds was based on spectroscopic analyses (IR, MS as well as 1-D and 2-D NMR experiments).
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Moura FS,Lima GS,Meneghetti MR,Lyra Lemos RP,Conserva LMdoi
10.1080/14786419.2010.507547subject
Has Abstractpub_date
2011-10-01 00:00:00pages
1614-20issue
17eissn
1478-6419issn
1478-6427journal_volume
25pub_type
杂志文章abstract::The aims of the present study were to determine the antibacterial activity of bark extract of Cryptomeria japonica D. Don and to isolate potential antibacterial constituents. The results showed that the ethanolic extract of C. japonica bark possessed a good antibacterial activity. Nine compounds including seven diterp...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802267510
更新日期:2008-01-01 00:00:00
abstract::Besides the chemotaxonomic value, nowadays determination of biodiversity and chemical variability has a commercial impact. The exact identity of raw material and constituents of botanical products, such as food supplements or herbal remedies, is a very important argument, being the real prerequisite for quality contro...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.852546
更新日期:2014-01-01 00:00:00
abstract::The present study was aimed to isolate active constituents from Blumea axillaris (Lam.) DC (Asteraceae) against phytopathogenic fungi. Bioactivity guided fractionation of the successive n-hexane, chloroform and methanol extract led to the isolation of the monoterpene ester (4 R,5S)-4-hydroxy-7-tigloyloxycarvotanaceton...
journal_title:Natural product research
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doi:10.1080/14786419.2020.1833197
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abstract::This study showed for the first time the antioxidant and hypoglycaemic properties of the methanol, n-hexane and ethyl acetate extracts from Senecio stabianus Lacaita, a plant that belongs to the Asteraceae family. The antioxidant activities were carried out using two different in vitro assays, namely 2,2-diphenyl-1-pi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.488233
更新日期:2012-01-01 00:00:00
abstract::This study was focused on in vitro cytotoxicity screening of the raspberry seeds methanol extract towards a number of cancer cell lines of human origin. The tested extract at the preferred concentrations (IC50 <30 µg/mL) inhibited only the growth of the lung cancer A-549 cells (IC50 = 14.07 ± 0.96 µg/mL). At the same ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1666391
更新日期:2019-09-17 00:00:00
abstract::The main purpose of this study was the characterisation of 'Serra da Lousã' heather honey by using novel statistical methodology, relevant principal component analysis, in order to assess the correlations between production year, locality and composition. Herein, we also report its chemical composition in terms of sug...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701825004
更新日期:2008-01-01 00:00:00
abstract::Six new compounds, colletobredins A-D (1-4) and colletomelleins A and B (5 and 6), along with 12 previously identified compounds, were isolated from the culture broth of Colletotrichum aotearoa BCRC 09F0161, a fungal endophyte residing in the leaves of an endemic Formosan plant Bredia oldhamii Hook. f. (Melastomatacea...
journal_title:Natural product research
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doi:10.1080/14786419.2015.1054285
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abstract::The study examined the radioprotective activity of an aqueous extract from Pleurotus ostreatus mycelium administered to Balb/c mice. Male mice were whole-body irradiated on day 0 ((60)Co, at 0.43 Gy/min) and divided into two groups. The extract was administered intraperitoneally to one group (100 mg/kg) on days - 10 t...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.983918
更新日期:2015-01-01 00:00:00
abstract::The actinomycete strain FIM06-0036 was isolated from marine sponge sample collected from the East China Sea and identified as Verrucosispora sp. based upon the results of 16S rRNA sequence analysis. One new alkaloid, 2-ethylhexyl 1H-imidazole-4-carboxylate (1), together with a known alkaloid butyl 1H-imidazole-4-carbo...
journal_title:Natural product research
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doi:10.1080/14786419.2019.1689498
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abstract::A new protein detector of 2,4,6-trinitrophenol (TNP, picric acid) is concisely reported herein for the first time. In brief, the gene of a specific scFv fragment, namely 3.5, was fused separately with the gene of β-lactamase and, subsequently, expressed in the periplasmic space of Escherichia coli, affording in such a...
journal_title:Natural product research
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doi:10.1080/14786419.2020.1860977
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abstract::EU and Italian laws dealing for the presence of antibiotics or, more in general, drags in food established limits for different kinds of food. Suitable rules exist about the medical treatment of cattle in relation to the production of milk and meat. The adoption of a procedure to check the respect of the law limits is...
journal_title:Natural product research
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doi:10.1080/14786419.2017.1392951
更新日期:2018-07-01 00:00:00
abstract::Bothrops jararacussu venom's (Bj2015) batch was biomonitored quarterly for one year to assess phospholipase A2 (PLA2) activity, immunogenicity, neurotoxicity, and myotoxicity. In silico models were applied to evaluate losses using decay model and recoveries by predictive trend analysis. Mice were immunized with Bj2015...
journal_title:Natural product research
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doi:10.1080/14786419.2018.1446010
更新日期:2019-08-01 00:00:00
abstract::A new HPLC-DAD method was developed and validated for simultaneous determination of six main phenylethanoid glycosides (calceolarioside D, neocalceolarioside D, verbascoside, isoverbascoside, leucoseptoside A and martynoside) in the aerial parts of four Scutellaria L. taxa from flora of Turkey. All standard compounds ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1486309
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abstract::Investigation of the aerial parts of Vernonia leopoldii (Sch. Bip.) Vatke afforded a new lanostane-type triterpene along with known hirsutinolide-type sesquiterpene lactones and flavonoid glycosides, all are identified for the first time in this species. The new compound was identified as lanost-3β, 23S-dihydroxy-22(3...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1062004
更新日期:2016-01-01 00:00:00
abstract::Using a bioactivity-guided fractionation procedure, five cembranolides, 11-epi-sinulariolide acetate (1), 11-dehydrosinulariolide (2), sinulariolide (3), dihydrosinularin (4), and 3,4:8,11-bisepoxy-7-acetoxycembra-15(17)-en-1,12-olide (5), along with two nucleosides, 2'-deoxyadenosine and thymidine, were isolated from...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786910310001617677
更新日期:2003-12-01 00:00:00
abstract::The present study was designed to evaluate the herbicidal activity of Datura metel against the noxious weed parthenium (Parthenium hysterophorus L.). In a laboratory bioassay, the effect of aqueous, methanol and n-hexane shoot and root extracts of 5, 10, 15 and 20% w/v (on a fresh weight basis) concentration of D. met...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410903075440
更新日期:2010-09-01 00:00:00
abstract::The chemical analyses of ethyl acetate-methanol (EtOAc-MeOH) extract of muricid gastropod mollusk, Chicoreus ramosus from the southeastern coast of Indian peninsular led to the identification of unprecedented cembrane-type diterpenoid, which was characterized as (3E, 6E, 10E)-8a-butoxy-17(15→14), 20(12→11)-bis-abeo-ce...
journal_title:Natural product research
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doi:10.1080/14786419.2018.1527833
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abstract::Analgesic and anti-inflammatory activities of the aqueous and ethanol extracts of Thespesia populnea Soland. ex. Correa (Malvaceae) leaves were evaluated in animal models. Orally-administered aqueous and ethanol extracts (100, 200 and 400 mg kg⁻¹ bw) showed significant analgesic activity in chemical-, mechanical- and ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.574134
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abstract::A novel macrolide with dioxa and double ring pentadecanone, named as phoxalone, isolated from the culture broth of a myxobacterium Sorangium cellulosum WXNXJ-C, was well investigated. The chemical structure of Phoxalone was elucidated by spectroscopic analysis including UV, IR, (1)H NMR, MALDI-TOF-MS, and LC/MS spectr...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701766190
更新日期:2007-12-01 00:00:00
abstract::Nine lupeol derivatives were synthesised and assayed in vitro for their antitumour activities against three human tumour cells lines, A549, LAC and HepG2. Of lupeol derivaties, six were new compounds, and five compounds against A549 cells, four compounds against HepG2 cells and three compounds against LAC cells were e...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1329729
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abstract::Trichosanthes dioica Roxb. (Cucurbitaceae), named 'pointed gourd' in English, is a dioecious climber grown in India. This study was aimed at evaluating the laxative activity of the aqueous extract of T. dioica root (TDA) in Swiss albino mice. The laxative activity of TDA (100 and 200 mg kg(-1) body weight per os) was ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.535161
更新日期:2012-01-01 00:00:00
abstract::Eurya acuminata DC and Croton caudatus Gieseler are two ethno-medicinal plants used by Kuki community of North East India. From these plants, we have characterized fifteen phytochemicals (1-15) by extensive use of chromatographic and spectroscopic methods. They were also tested for in vitro cytotoxic effects against A...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1815737
更新日期:2020-09-16 00:00:00
abstract::Thirteen phenones were obtained from the 70% ethanol extract of Paeonia suffruticosa Andrews. Their structures were determined on the basis of chemical methods and spectral data. Among them, compound 1 was identified as a new compound, and compounds 5 and 13 were obtained from genus Paeonia for the first time. The inh...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1230114
更新日期:2017-02-01 00:00:00
abstract::The ethanolic extract of the stems of Viburnum fordiae Hance showed insecticidal and α-glucosidase inhibitory activities and then was fractionated by bioactivity-guided fractionation to obtain a rare C13-norisoprenoid (1), together with a new phenolic glycoside (2), and seven known compounds, alangionoside C (3), pisu...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1466130
更新日期:2019-09-01 00:00:00
abstract::A high performance liquid chromatography-time-of-flight-mass spectrometry (HPLC-TOF-MS) method was developed for analysing the chemical constituents in Hedyotis diffusa, which is widely used as a traditional Chinese medicine (TCM) in the field of cancer treatment. The compounds were identified either by comparing the ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.537275
更新日期:2012-01-01 00:00:00
abstract::The essential oil of the 'resurrection plant' Myrothamnus moschatus (Baillon) Niedenzu endemic to Madagascar, where it is used in traditional medicine, was investigated for the first time for some biological activities. GC-FID and GC-MS analyses revealed trans-pinocarveol (35.6%), pinocarvone (20.0%), β-selinene (8.5%...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.665916
更新日期:2012-01-01 00:00:00
abstract::Essential oils hydrodistilled from the leaves and stem barks of Goniothalamus macrocalyx Ban., Goniothalamus albiflorus Ban. and Goniothalamus tamirensis Pierre ex Fin. & Gagnep. growing in Vietnam were analysed by gas chromatography (GC) and GC-coupled with mass spectrometry. α-Pinene (1.7-50.0%), β-pinene (tr-6.8%),...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.814051
更新日期:2013-01-01 00:00:00
abstract::The aim of this work was to provide information about kinetin effects on chemical volatile profile of Curcuma zedoaria (Christm.) Roscoe after several days of plant dormancy release. Rhizomes of C. zedoaria were immersed in four kinetin concentrations (0, 50, 100, 150 mg ml-1, n = 12 by each concentration) for 30 min....
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1729152
更新日期:2020-02-21 00:00:00
abstract::A total of 25 compounds including terpenoids, flavonoids, biflavonoids and ginkgolic acids were identified and quantified with a reliable, simple, and simultaneous method from Ginkgo leaves, seed coats and embryoids with different tree ages (approximately identified as 25, 500, 1000 and 2000 years). Leaves had the hig...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1788020
更新日期:2020-07-01 00:00:00
abstract::Chemical investigation of the mycelial extract of a mixed culture of two marine alga-derived fungal strains of the genus Aspergillus has yielded one new cyclotripeptide, psychrophilin E (1), the recently reported oxepin-containing alkaloids, protuboxepin A (2) and oxepinamide E (3), together with three other polyketid...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.880911
更新日期:2014-01-01 00:00:00