Abstract:
:A new furostanol saponin, (25R)-26-O-(α-d-glucopyranosyl)-(1→2)-α-l-rhamnopyranosyl-furost-5-ene-3β, 22α, 26-triol-3-O-α-d-glucopyranoside (1), together with four known compounds 2-5 were isolated from the ethanolic extract of the stems of Dendrobium chrysanthum Lindl. The structures of these new compounds were identified by extensive spectroscopic analysis including 1D and 2D NMR and HR-ESI-MS, as well as chemical methods. Compounds 1-3 were isolated from D. chrysanthum for the first time. Furthermore, the inhibitory effects of the compounds on tumor cells were evaluated, and compounds 1-2 exhibited significant cytotoxic activities potentially against SPC-A1, MCF-7 and HeLa human cancer cell lines. Compounds 3-5 showed inhibitory activity against the SPC-A1 and MCF-7.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Yang C,Lin W,Zhao L,Cai Jdoi
10.1080/14786419.2018.1452007subject
Has Abstractpub_date
2019-09-01 00:00:00pages
2461-2465issue
17eissn
1478-6419issn
1478-6427journal_volume
33pub_type
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