Abstract:
:In Brazilian folk medicine, Protium heptaphyllum is used to treat inflammatory conditions and to hasten wound repair. This paper aims to investigate the chemical composition and the in vitro antibacterial effects of the essential oils (EOs) obtained from P. heptaphyllum leaves and ripe and unripe fruits against a representative panel of oral pathogens. The GC-FID and GC-MS analysis revealed that the major components determined in P. heptaphyllum essential oils were myrcene (59.0%), β-elemene (17.2%), limonene (12.9%), spathulenol (12.6%), α-cubebene (11.6%), germacrene D (10.6%), trans-nerolidol (9.8%), and α-cadinol (8.8%). The essential oils of the ripe and unripe fruits showed the strongest antibacterial activity against the anaerobic bacteria Prevotella nigrescens (MIC = 50 µg/mL). The leaf essential oil displayed very promising activity against Streptococcus mutans (MIC = 50 µg/mL) and Streptococcus mitis (MIC = 62.5 µg/mL). The antibacterial activity of EOs against oral pathogens is also described for the first time. [Formula: see text].
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Cabral RSC,Alves CCF,Batista HRF,Sousa WC,Abrahão IS,Crotti AEM,Santiago MB,Martins CHG,Miranda MLDdoi
10.1080/14786419.2018.1536659subject
Has Abstractpub_date
2020-08-01 00:00:00pages
2378-2383issue
16eissn
1478-6419issn
1478-6427journal_volume
34pub_type
杂志文章abstract::A new furan derivative named 3-(5-oxo-2,5-dihydrofuran-3-yl) propanoic acid (1) was isolated for the first time. Its structure was elucidated by UV, IR, NMR, HR-ESI-MS and the single-crystal X-ray diffraction spectroscopic data. Meanwhile, the antifungal and antibacterial activities of compound 1 was tested, it exhibi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1501687
更新日期:2019-10-01 00:00:00
abstract::Two new flavonoid glycosides, kaempferol 3-O-α-L-rhamnopyranosyl (1→6) (3''-acetyl)-β-D-galactopyranoside 1 and kaempferol 3-O-α-L-arabinopyranosyl-5-O-α-L-rhamnopyranoside 2, along with six known ones 3-8 were isolated from the flowers of Vicia faba L. (Fabaceae). Methanol extract and the isolated compounds were test...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1359169
更新日期:2018-08-01 00:00:00
abstract::The anticancer activity of ethanol extract isolated from Goji berry (EEGB) on T47D human breast cancer cell line has been reported. Cell viability and cell proliferation were examined with the use of BrdU, MTT and NR methods. Induction of apoptosis was assessed by propidium iodide and Hoechst 33342 staining. Expressio...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1101691
更新日期:2016-09-01 00:00:00
abstract::Two new glycerol esters, (S)-2-hydroxy-3-(octanoyloxy)propyl tetracosanoate (1) and (S)-3-(((S)-11-acetoxy octadecanoyl)oxy)propane-1,2-diyl diacetate (2), and eight known compounds, docosanedioic acid (3), 2,5-dimethylnonadecane (4), lupeol (5), stigmasterol (6), β-sitosterol (7), heptadecanoic acid (8), hexanedioic ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1777117
更新日期:2020-06-12 00:00:00
abstract::Phytochemical investigation of the aerial parts of Eriope blanchetii and E. latifolia (Lamiaceae) yielded podophyllotoxin, as well as the aryltetralin lignans α- and β-peltatin and yatein. Oleanolic, ursolic and epikatonic acids were also isolated. This is the first occurrence of podophyllotoxin in the family. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410902809500
更新日期:2011-09-01 00:00:00
abstract::Chemical investigation of Trogopterus faeces has led to the isolation of seven flavonoids. Their structures were elucidated by chemical and spectral analyses. In an anticoagulative assay, three kaempferol coumaroyl rhamnosides had significant antithrombin activity. This is the first report on the occurrence of flavono...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.482057
更新日期:2010-11-01 00:00:00
abstract::Two new C-15 enolic acyl phragmalin-type limonoid orthoesters, chukvelutilide G (1) and chukrasine F (2), were isolated from the stem barks of Chukrasia tabularis var. velutina. Their structures were elucidated by their extensive high resolution-electrospray ionization mass spectrometry (HR-ESI-MS), one- and two-dimen...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.682995
更新日期:2013-04-01 00:00:00
abstract::The use of natural products as a diet supplement is increasing worldwide but sometimes is not followed by adequate sanitary controls and analyses. Twenty samples of pills and capsules of lyophilised cyanobacteria (blue-green algae), commercialised in Italy as dietary supplements, were found positive at the Vibrio fisc...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410500410859
更新日期:2006-07-20 00:00:00
abstract::Leaves of Kalanchoe pinnata are used worldwide for healing skin wounds. This study aimed to develop and compare two creams containing a leaf aqueous extract of K. pinnata (KP; 6%) and its major flavonoid [quercetin 3-O-α-L-arabinopyranosyl-(1→2)-α-L-rhamnopyranoside] (0.15%). Both creams were topically evaluated in a ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1817012
更新日期:2020-09-14 00:00:00
abstract::This article investigates the effect of microwaves on the amount of volatile compounds Achillea tenuifolia Lam with two methods, headspace single-drop microextraction and microwave-assisted headspace single-drop microextraction (MA-SDME), for the analysis of essential oil. Solvent selection, solvent volume, microwave ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1079911
更新日期:2016-01-01 00:00:00
abstract::Chronic administration of myricetin (100 and 300 mg kg⁻¹, p.o., for 4 weeks) isolated from Vitis vinifera (Vitaceae) ameliorated hypertension and oxidative stress induced by deoxycorticosterone acetate (DOCA)-salt in rats. Myricetin treatment reduced systolic blood pressure, vascular reactivity changes and reversed th...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410903335190
更新日期:2011-09-01 00:00:00
abstract::One new 14-membered ring cyclopeptide alkaloid, plenane A (1), along with six known compounds (2-7), was isolated from the roots of Clematis florida. Their structures were elucidated by means of NMR spectroscopic analysis and mass spectrometry. In addition, their anti- inflammatory effects on lipopolysaccharide-induce...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1809399
更新日期:2020-08-18 00:00:00
abstract::The phytochemical investigation of the stem bark of Tinospora cordifolia Miers (Menispermaceae) has afforded four new compounds, named tinosporafuranol, tinosporafurandiol, tinosporaclerodanol, and tinosporaclerodanoid, along with beta-sitosterol, and their stereostructures have been elucidated correspondingly as 4-se...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802435679
更新日期:2010-06-01 00:00:00
abstract::Antimicrobial potential of medicinal plants have been explored extensively these days. This study was carried out to evaluate the antibacterial potential from aerial parts of plant, called 'Annona senegalensis' and its constituents. Bioassay guided fractionation led to the isolation of four metabolites, (+)-catechin (...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1263847
更新日期:2017-08-01 00:00:00
abstract::Phytochemical investigation of the stem and root barks of Friesodielsia obovata Benth (Annonaceae) afforded new 3',5'-diformyl-2',4',6'-trihydroxychalcone and N-formyl-7-hydroxyglaucine together with five known compounds, 3',5'-dimethyl-2',4',6'-trihydroxychalcone, (-)-crotepoxide, demethoxymatteucinol, lawinal, and b...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701194310
更新日期:2007-09-01 00:00:00
abstract::The aim of this study was to investigate mercury accumulation in some species, caught in Mediterranean Sea, in the period between May and December 2015, and to compare it to the presence of Anisakis parasites. The samples were examined by direct mercury analyzer (DMA-80) for their Hg levels. The metal concentration wa...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1230119
更新日期:2017-05-01 00:00:00
abstract::Oldenlandia umbellata L., commonly known as 'chay root', belongs to the family Rubiaceae and is one of the unexplored dye-yielding plants. The roots from this plant are the sources of red dye. Extraction protocol and dye characterisation have not been completely studied so far in this plant. Hence, in this article we ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802696635
更新日期:2009-01-01 00:00:00
abstract::GC/FID and GC-MS analysis revealed germacrene D, bicyclogermacrene, α-cadinol and cubenol as major compounds from aril. Germacrene D, bicyclogermacrene, trans-caryophyllene and δ-elemene are major compounds in fruits. Germacrene D, spathulenol, trans-caryophyllene and caryophyllene oxide are major compounds in leaves....
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.987145
更新日期:2015-01-01 00:00:00
abstract::Cinobufagin (CBF) is an active ingredient isolated from Venenum Bufonis extracted and dried from the secretory glands of Bufo gargarizans Cantor. The purpose of the study was to investigate the effects and underlying mechanisms of CBF on human breast cancer MCF-7 cells in vitro. Our results showed that CBF exhibited o...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1315575
更新日期:2018-02-01 00:00:00
abstract::A new triterpenic glucoside, lup-1,5,20(29)-trien-3-O-beta-D-glucopyranoside (4), along with three known phytoconstituents: n-octacosane, friedelin and beta-amyrin, has been isolated from the leaves of Clerodendrum inerme (L.) Gaertn. (Verbenaceae). Structure elucidation was carried out on the basis of chemical and ph...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410902975566
更新日期:2010-01-01 00:00:00
abstract::32 medicinal plants that are unique to the Russian Pharmacopeia have 693 isolated natural products associated with them (an average of 21.66 compounds per plant). This is in contrast to the US Pharmacopeia plants that have delivered 2366 known natural products (an average of 42.25 compounds per plant). ...
journal_title:Natural product research
pub_type: 信件
doi:10.1080/14786419.2020.1727474
更新日期:2020-02-21 00:00:00
abstract::The first chemotaxonomic study based on volatile components of Porella viridissima (Mitt.) Grolle is reported. The GC-MS analysis of ether extract was performed; ten santalane and five pinguisane-type sesquiterpenes were identified together with perrottetianal A as major diterpene. Most of detected santalane-type sesq...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1655022
更新日期:2019-08-23 00:00:00
abstract::Phytochemical investigation of the methanolic extract of Vangueria agrestis aerial parts led to the isolation and characterization of four monoterpene rhamnosides, two ursane saponins, and six flavonoid glycosides. Of these constituents, are three undescribed monoterpene glycosides, vangagrestosides A-C. The reported ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1731744
更新日期:2020-02-24 00:00:00
abstract::The cholesteryl ester transfer protein (CETP), inhibition of which assists in maintaining a high level of high-density lipoprotein cholesterol in the blood, is a target for anti-atherosclerosis treatments. Orange monascus pigment was produced by a Monascus species in a 5 L jar fermenter and various derivative compound...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.905561
更新日期:2014-01-01 00:00:00
abstract::The actinomycete strain FIM06-0036 was isolated from marine sponge sample collected from the East China Sea and identified as Verrucosispora sp. based upon the results of 16S rRNA sequence analysis. One new alkaloid, 2-ethylhexyl 1H-imidazole-4-carboxylate (1), together with a known alkaloid butyl 1H-imidazole-4-carbo...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1689498
更新日期:2019-11-15 00:00:00
abstract::One new neolignan glycoside, dolomiside A (1), together with 11 known phenylpropanoid glycosides were isolated from Dolomiaea souliei (Franch.) Shih. The structures of these isolates were determined by UV, CD, HR-ESI-TOFMS, 1D and 2D NMR analysis. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1552695
更新日期:2020-04-01 00:00:00
abstract::Evaluation of in vitro standard antioxidant assays, such as 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2'-azino-bis-3 ethylbenzothiozoline-6-sulphonic acid diammonium salt (ABTS+) radical scavenging, lipid peroxidation inhibitory (or thiobarbituric acid formation inhibitory activity) and ferrous ion (Fe+2) chelating acti...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1375923
更新日期:2018-11-01 00:00:00
abstract::Two new fatty acid esters of triterpenoids (1-2) together with eleven known compounds (3-13) were obtained after investigation of the CH2Cl2-MeOH (1:1) crude extract from the leaves of Schefflera barteri Harms. All these compounds (1-13) were isolated for the first time from this plant among which compounds 3, 4, 6 an...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1849199
更新日期:2020-11-18 00:00:00
abstract::Two new iridoids namely valerialloside A and valerianoside A (1 and 2) along with five known compounds (3-7) were isolated from the roots of Valeriana jatamansi Jones. The structure of new compounds were determined using 1D and 2D NMR including 1H-1H COSY, HSQC, HMBC and NOESY spectroscopic techniques. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1858412
更新日期:2020-12-09 00:00:00
abstract::The mechanism of inhibition of jack bean and Bacillus pasteurii ureases was investigated by triacontanyl palmitate (1) which is a long-chain fatty ester and has been isolated from Symplocos racemosa Roxb. Lineweaver-Burk, Dixon plots, and their secondary replots showed that 1 is a non-competitive inhibitor of these en...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410600906913
更新日期:2007-07-10 00:00:00