Two new triterpenoid fatty acid esters from Schefflera barteri Harms (Araliaceae)§.

Abstract:

:Two new fatty acid esters of triterpenoids (1-2) together with eleven known compounds (3-13) were obtained after investigation of the CH2Cl2-MeOH (1:1) crude extract from the leaves of Schefflera barteri Harms. All these compounds (1-13) were isolated for the first time from this plant among which compounds 3, 4, 6 and 9-13 were also isolated from the genus Schefflera for the first time. The structures of the isolated compounds were elucidated by analyses of their spectroscopic data (1D and 2D NMR, and MS). The antibacterial and cytotoxic activities of crude extracts, fractions and compounds (1, 2, 5, 6, 8 and 9) were investigated against both Gram-negative and Gram-positive bacteria strains as well as on human cervix carcinoma and colon adenocarcinoma cancer cell lines, respectively. They showed weak to significant activity towards the strains and malignant cells used.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Mbougnia JFT,Bitchagno GTM,Wouamba SCN,Jouda JB,Awouafack MD,Tene M,Lenta BN,Kouam SF,Tane P,Sewald N

doi

10.1080/14786419.2020.1849199

subject

Has Abstract

pub_date

2020-11-18 00:00:00

pages

1-12

eissn

1478-6419

issn

1478-6427

pub_type

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