Three new phenanthrenes, a new stilbenoid isolated from the roots of Stemona tuberosa Lour. and their cytotoxicity.

Abstract:

:Three new phenanthrenes, stemophenanthrenes A-C (1-3), along with one new stilbenoid, isopinosylvin A (4) and a known compound methyl ferulate (5), were isolated and identified from the roots of Stemona tuberosa Lour. plants, collected in Attapu province (Laos). Their structures were elucidated by spectroscopic analysis (FT-ICR-MS, IR, UV, 1D and 2D NMR). These compounds show moderate cytotoxic activity against four cancer cell lines, KB (a human epidermal carcinoma), MCF7 (human breast carcinoma), SK-LU-1 (human lung carcinoma) and HepG2 (hepatocellular carcinoma).

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Khamko VA,Quang DN,Dien PH

doi

10.1080/14786419.2013.832677

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

2328-32

issue

24

eissn

1478-6419

issn

1478-6427

journal_volume

27

pub_type

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