A new cyclopeptide alkaloid from Clematis Florida.

abstract：:This study was designed to characterise the effects of evodiamine on intestinal contractility and reveal the correlated mechanisms. Evodiamine (2.5-80.0 μM) increased normal jejunal contractility and jejunal hypocontractility established under a variety of experimental conditions. Evodiamine-exerted stimulatory effect...

journal_title：Natural product research

authors： Xiong YJ,Chen DP,Peng JY,Wang JY,Lv BC,Liu FF,Lin Y

更新日期：2015-01-01 00:00:00

abstract：:The natural product lupeol 1 was isolated from aerial parts of Vernonia scorpioides with satisfactory yield, which made it viable to be used as starting material in semisynthetic approach. Ten lupeol derivatives 2-11 were prepared by classical procedures. Including, five new esters derivatives 7-11, which were obtaine...

journal_title：Natural product research

authors： Machado VR,Sandjo LP,Pinheiro GL,Moraes MH,Steindel M,Pizzolatti MG,Biavatti MW

更新日期：2018-02-01 00:00:00

abstract：:A new polycyclic polyprenylated acylphloroglucinol (1), nujiangefolin D, together with five known analogues (2-6), were isolated from the fruits of Garcinia nujiangensis. Compound 1 was screened by the LC-MS and LC-PDA. The structure of 1 was elucidated on the basis of extensive spectroscopic techniques including 1 D ...

journal_title：Natural product research

authors： Tang Z,Lu L,Zhou X,Shen J,Song W,Tang Y,Xia Z

更新日期：2020-09-01 00:00:00

abstract：:A new cytisine-type alkaloid, along with five known alkaloids was obtained from the seeds of Sophora alopecuroides. Their structures were determined to be (-)-N-(2'-hydroxy-3',5'-di-tert-butyl-toluene)-cytisine (1), (-)-lupanine (2), (+)-matrine (3), (+)-sophoramine (4), (+)-lehmannine (5) and (-)-sophocarpine (6). Th...

journal_title：Natural product research

authors： Rong ZJ,Gao XX,Hu GS,Yan T,Jia JM,Wang AH

更新日期：2020-09-23 00:00:00

abstract：:Phytochemical investigation of the methylenechloride/methanol extract of the aerial parts of Stachys aegyptiaca afforded a new neoclerodane-type diterpene with a new side chain 1, in addition to two known diterpenes 2 and 3 and a known flavonoid glycoside 4. The structures of the compounds were determined by comprehen...

journal_title：Natural product research

authors： Mohamed Ael-H,Mohamed NS

更新日期：2014-01-01 00:00:00

abstract：:Two new monoterpene esters illigerates F and G (1 and 2) together with 5 know compounds illigerate A (3), illigerate C (4), actinodaphnine (5), N-methylactinodaphnine(6) and N-methyllaurotetanine(7) were isolated from Illigera aromatica S. Z. Huang et S. L. Mo. Their structures were identified by extensive NMR data an...

journal_title：Natural product research

authors： Pu XY,Tian K,Sun JX,Wang W,Liu HC,Yang J,Jiang MY,Huang XZ

更新日期：2019-05-28 00:00:00

abstract：:Two new lanostane triterpnenoids named endertiins A and B (1 and 2) together with two known compounds as ganodecalone A (3) and ergosterol (4) have been successfully isolated from the cultivated fruit bodies of the mushroom Humphreya endertii Stey (Ganodermataceae). Their structures were elucidated by a combination of...

journal_title：Natural product research

authors： Quang DN,Long LD,Tung NQ,Thanh NN,Tham LX

更新日期：2020-08-03 00:00:00

abstract：:Two new benzoic acid derivatives, named methyl(S)-3-hydroxy-4-(2- hydroxy -6-methylheptan-2-yl)benzoate (1) and 2-hydroxy-3-(6- hydroxy-6-methylhept-1-en-2-yl)benzoic acid (2), were isolated from the ethanol extract of an endophytic fungus Aspergillus versicolor derived from the medicinal plant Euphorbia royleana. The...

journal_title：Natural product research

authors： Ye Y,Chen Y,Hou Y,Yu H,Zhu L,Sun Y,Zhou M,Chen Y,Dong M

更新日期：2020-06-11 00:00:00

abstract：:The CDC25 phosphatases regulate the cell division cycle by controlling the activity of cyclin-dependent kinases. While screening for inhibitors of phosphatases among natural products we repeatedly found that some polyprenyl-hydroquinones and polyprenyl-furans (furanoterpenoids) (furospongins, furospinosulins) were pot...

journal_title：Natural product research

authors： Erdogan-Orhan I,Sener B,de Rosa S,Perez-Baz J,Lozach O,Leost M,Rakhilin S,Meijer L

更新日期：2004-02-01 00:00:00

abstract：:To search for anti-diabetic and insulin-sensitising natural products, the effect on adipocyte differentiation was investigated by assessing fat accumulation in 3T3-L1 preadipocytes using Oil Red O staining. Fractionation and separation of n-hexane and CHCl₃ fractions of Morinda officinalis (Rubiaceae) using several ch...

journal_title：Natural product research

authors： Liu Q,Kim SB,Ahn JH,Hwang BY,Kim SY,Lee MK

更新日期：2012-01-01 00:00:00

abstract：:The present work describes the metabolites produced by a strain identified as Streptomyces youssoufiensis, whose secondary metabolites profile has not been studied so far. The crude ethyl acetate extract was analyzed by high performance liquid chromatography-electrospray ionization mass spectrometry, leading to the de...

journal_title：Natural product research

authors： Leulmi N,Sighel D,Defant A,Khenaka K,Boulahrouf A,Mancini I

更新日期：2019-01-01 00:00:00

abstract：:This study describes the seasonal composition and the antibacterial, antioxidant and anticholinesterase activity of the essential oil from Eugenia brasiliensis leaves. Analysis by using GC allowed the identification of 40 compounds. It was observed that the monoterpenes varied more (42%) than the sesquiterpenes (14%),...

journal_title：Natural product research

authors： Siebert DA,Tenfen A,Yamanaka CN,de Cordova CM,Scharf DR,Simionatto EL,Alberton MD

更新日期：2015-02-01 00:00:00

abstract：:Two new compounds, one sesquiterpene lactone (1) and one phenylethanoid tautomer (2), together with eleven known compounds (3-13) were isolated from the leaves of Ixeridium dentatum. Their structures were determined by extensive spectroscopic methods, including 1D-, 2D-NMR, and mass spectrometry. All compounds were ev...

journal_title：Natural product research

authors： Park S,Nhiem NX,Park JH,Bhattarai KR,Chae HJ,Kim HR,Kim SH

更新日期：2019-04-10 00:00:00

abstract：:Twenty-one phenolic compounds (1-21) including dihydrocinnamic acid, isoflavonoids, flavonoids, coumestans, pterocarpans, chalcones, isoflavan and isoflaven, were isolated from the roots of Glycyrrhiza pallidiflora Maxim. Phloretinic acid (1), chrysin (6), 9-methoxycoumestan (8), isoglycyrol (9), 6″-O-acetylanonin (19...

journal_title：Natural product research

authors： Shults EE,Shakirov MM,Pokrovsky MA,Petrova TN,Pokrovsky AG,Gorovoy PG

更新日期：2017-02-01 00:00:00

abstract：:As part of continuing our research on diverse C-7 derivatives of camptothecin (CPT), 16 CPT derivatives bearing piperazinyl-thiourea chemical scaffold and different substituent groups have been designed, synthesized and evaluated in vitro for cytotoxicity against five tumor cell lines (A-549, MDA-MB-231, MCF-7, KB and...

journal_title：Natural product research

authors： Song ZL,Yang GZ,Li JC,Liu YQ,Yang CJ,Goto M,Zhang ZJ,Morris-Natschke SL,Liu H,Lee KH

更新日期：2020-07-01 00:00:00

abstract：:Cinobufagin (CBF) is an active ingredient isolated from Venenum Bufonis extracted and dried from the secretory glands of Bufo gargarizans Cantor. The purpose of the study was to investigate the effects and underlying mechanisms of CBF on human breast cancer MCF-7 cells in vitro. Our results showed that CBF exhibited o...

journal_title：Natural product research

authors： Zhu L,Chen Y,Wei C,Yang X,Cheng J,Yang Z,Chen C,Ji Z

更新日期：2018-02-01 00:00:00

abstract：:A phytochemical study of Asplenium ruta-muraria L. (Aspleniaceae) led to the isolation of a new caffeic acid glycoside, 2-O-caffeoyl-β-D-fructofuranosyl-(2 → 1)-α-D-glucopyranoside and an (α, β)-isomeric pair of 2E-caffeoyl-D-glucopyranoside, together with kaempferol-3-O-β-D-[6-E-caffeoyl-β-D-glucopyranosyl-(1 → 2)glu...

journal_title：Natural product research

authors： Fan P,Zhao L,Hostettmann K,Lou H

更新日期：2012-01-01 00:00:00

abstract：:Moringa oleifera Lam. family Moringaceae is well known for a wide range of biological activities and a complex phytochemical composition. The current study investigates tissue culture protocols for Moringa oleifera leaves and seeds. For static culture initiation, Murashige and skooge (MS) as a basal medium with hormon...

journal_title：Natural product research

authors： Mustafa R,El-Naggar EMB,Svajdlenka E,Omran G,ELFiky F,El-Hawiet A

更新日期：2020-03-25 00:00:00

abstract：:New ent-trachylobane-3β-hydroperoxide (5) together with four known compounds, ricinine (1), trimethoxy ellagic acid (2), dimethoxy ellagic acid (3) and aleurotolic acid (4) were isolated from the methylene chloride fraction of the root bark of Chrozophora oblongifolia. The structures of these secondary metabolites wer...

journal_title：Natural product research

authors： Kamel MR,Nafady AM,Hassanein AMM,Hassan AR,Shimizu K,Ibrahim RR,Haggag EG

更新日期：2019-11-06 00:00:00

abstract：:This paper aims to investigate, for the first time, physicochemical characteristics and antioxidant capacity of Psidium myrtoides ripe and unripe fruit. In addition, essential oil was extracted from fresh leaves (PM-EO) collected in dry and rainy seasons to investigate the influence of seasonality and, after that, to ...

journal_title：Natural product research

authors： Dias ALB,Batista HRF,Sousa WC,Bailão EFLC,Rocha JD,Sperandio EM,Fernandes CC,Souchie EL,Miranda MLD

更新日期：2020-11-09 00:00:00

abstract：:Eurya acuminata DC and Croton caudatus Gieseler are two ethno-medicinal plants used by Kuki community of North East India. From these plants, we have characterized fifteen phytochemicals (1-15) by extensive use of chromatographic and spectroscopic methods. They were also tested for in vitro cytotoxic effects against A...

journal_title：Natural product research

authors： Neipihoi,Narzary B,Saikia S,Saikia S,Tamuli KJ,Sahoo RK,Dutta D,Bordoloi M

更新日期：2020-09-16 00:00:00

abstract：:A new compound decomposed from ginkgolide B(GB) is discovered and identified by MS and UV spectrum. It is the dehydrate of GB, which was named as ginkgolide K before. Differently, it cannot exist independently, but only in equilibrium with GB. It is found first time that 3-hydroxy is active in some solvent. ...

journal_title：Natural product research

authors： Yuan C,Pan J,Hu X

更新日期：2008-01-01 00:00:00

abstract：:Four new and seven known diterpenes have been isolated from the dichloromethane extract of the aerial parts of Calceolaria polifolia. The structures of the new compounds were established by spectroscopic evidence. ...

journal_title：Natural product research

authors： Garbarino JA,Piovano M,Chamy MC,Espinoza L

更新日期：2007-02-01 00:00:00

abstract：:This research work involves the dyeing of acrylic fabric with natural dye extracted from date pits powders using Soxhlet extraction process. The effect of dye bath pH, salt concentration, dyeing time and temperature were studied. The optimal dyeing conditions where pH 4, 0 g/L salt, 60 min, and 80 °C. The COD and the ...

journal_title：Natural product research

authors： Dhahri H,Guesmi A,Ben Hamadi N

更新日期：2019-05-01 00:00:00

abstract：:Two new C13-norsesquiterpenes claulanterpene A (1) and B (2), together with two known sesquiterpenes (3-4), were isolated from methanol extract of the stem and leaf of Clausena lansium collected from Qingyuan county, Guangdong Province, China. Their structures were elucidated on the base of extensive spectroscopic ana...

journal_title：Natural product research

authors： Liu XY,Fu XX,Li YY,Xiong ZH,Li BT,Peng WW

更新日期：2020-03-25 00:00:00

abstract：:Phytochemical investigation of the methanol extract of Euchresta formosana resulted in the isolation of thirty-four compounds. Compounds 1, 3-12, 15, 27, 29 and 32-24 were isolated from this species for the first time. These compounds were identified by spectral analyses and tested for antiplatelet aggregation and ant...

journal_title：Natural product research

authors： Lo WL,Wu CC,Chang FR,Wang WY,Khalil AT,Lee KH,Wu YC

更新日期：2003-04-01 00:00:00

abstract：:Santolina insularis is a Sardinian endemism that is widely used in traditional medicine. The essential oil was obtained with a yield of 2.7% and is mainly characterized by β-phellandrene (22.6%), myrcene (11.4%) and artemisia ketone (7.6%). The oil significantly reduced NO production without affecting macrophages viab...

journal_title：Natural product research

authors： Alves-Silva JM,Piras A,Porcedda S,Falconieri D,Maxia A,Gonçalves MJ,Cruz MT,Salgueiro L

更新日期：2020-06-04 00:00:00

abstract：:Chemical investigation of the stems of Epigunum griffithianum led to the isolation and identification of a new triterpenoid saponin (1) and two known compounds (epigynosides A (2) and B (3)). These structures were elucidated by means of spectroscopic analysis (1D and 2D NMR, MS, UV, IR) as well as comparison with the ...

journal_title：Natural product research

authors： Wang Q,Li WY,Wang YD

更新日期：2020-05-01 00:00:00

abstract：:Our laboratories have been investigating biological effects of a sesquiterpenoid polygodial and its natural and synthetic analogues. Herein, we report the evaluation of these compounds against the three forms of Trypanosoma cruzi, amastigotes, trypomastigotes and epimastigotes. Although polygodial was found to be poor...

journal_title：Natural product research

authors： Turner DN,Just J,Dasari R,Smith JA,Bissember AC,Kornienko A,Rogelj S

更新日期：2019-04-28 00:00:00

abstract：:Lappaconitine is an important alkaloid of the aconite family and its biological activity is closely related to its structure. Through an X-ray structure analysis of hydrated lappaconitine hydrobromide, which was synthesised by us through a new method, the absolute configuration of lappaconitine was determined: monocli...

journal_title：Natural product research

authors： Sun W,Wang Y,Zhang J,Yu K

更新日期：2009-01-01 00:00:00