Enhancement of phenolic and flavonoids compounds, antioxidant and cytotoxic effects in regenerated red cabbage by application of Zeatin.

Abstract:

:This study evaluated the roles of zeatin (2 mg/L) on direct organogenesis, phytochemical compounds, antioxidant activity, and cytotoxic activity in regenerated shoots of red cabbage. The results revealed that the extract of explant treated by 2 mg/L zeatin gives the highest content of total phenolics (5.18 mg gallic acid equivalent/g dry weight) and flavonoids (1.52 mg rutin equivalent/g dry weight). Moreover, HPLC and GC-MS analyses indicated that various bioactive compounds in red cabbage are significantly enhanced with increasing zeatin concentration. Besides that, antioxidant activity test showed that in vitro shooting culture using 2 mg/L zeatin displayed higher antioxidant activity in all assays (DPPH, FRAP and ABTS) compared to control with respective values of 68.12%, 73.28%, and 54.1%, respectively. Finally, the cytotoxic properties illustrated that the extracts of red cabbage explant treated by 2 mg/L zeatin exhibited the strongest cytotoxic effect towards cancer cells compared to control.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Ravanfar SA,Karimi E,Mehrabanjoubani P,Ebrahimi M

doi

10.1080/14786419.2018.1508145

subject

Has Abstract

pub_date

2020-03-01 00:00:00

pages

898-902

issue

6

eissn

1478-6419

issn

1478-6427

journal_volume

34

pub_type

杂志文章
  • A new highly oxygenated pseudoguaianolide with 5-LOX inhibitory activity from Rudbeckia hirta L. flowers.

    abstract::A new highly oxygenated pseudoguaianolide, rudbeckolide (1), was isolated from Rudbeckia hirta L. flowers. The structure of this terpenoid lactone was established on the basis of extensive 1D and 2D NMR spectroscopic analyses. The compound exhibited strong 5-lipoxygenase inhibitory activity (84.9% inhibition at 10 μg/...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2013.825916

    authors: Michael BR,Gedara SR,Amer MM,Stevenson L,Ahmed AF

    更新日期:2013-01-01 00:00:00

  • Polyphenol content in white table grape (Vitis Vinifera) berries of cultivar Italia: interactive effect of irrigation, delayed harvest and storage.

    abstract::Polyphenol concentrations were quantified by rapid resolution liquid chromatography/mass spectrometry in white table grape. The experimental vineyard was subjected to different kinds of water supply and supply rates. Samples from the same vineyards were also analysed after 6 weeks of storage in a refrigerator and afte...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2011.606623

    authors: Capriotti AL,Caruso G,Cavaliere C,Foglia P,Laganà A,Samperi R

    更新日期:2012-01-01 00:00:00

  • Design, synthesis and insecticidal activity of novel semicarbazones and thiosemicarbazones derived from chalcone.

    abstract::Thirty semicarbazone and thiosemicarbazone derivatives (2a-w and 4a-g) from chalcones containing furan and thiophene ring were designed and synthesized. They were characterized by IR, 1H NMR, 13C NMR and HRMS. The crystal structure of compound 2r was characterized by single crystal X-ray diffraction. It crystallizes i...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1739679

    authors: Cheng W,Xiao T,Qian W,Lu T,Zhang T,Tang X

    更新日期:2020-03-16 00:00:00

  • Furylhydroquinones and miscellaneous compounds from the roots of Lithospermum erythrorhizon and their anti-inflammatory effect in HaCaT cells.

    abstract::One new furylhydroquinone derivative (1) and seven known compounds (2-8) were isolated from the roots of Lithospermum erythrorhizon Sieb. et Zucc (Boraginaceae). The structure of 1 was elucidated by extensive spectroscopic methods using NMR and MS. The absolute configuration of shikonofuran J (1) was unambiguously det...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1431632

    authors: Ahn J,Chae HS,Chin YW,Kim J

    更新日期:2019-06-01 00:00:00

  • Chemical and biomolecular analyses to discriminate three taxa of Pistacia genus from Sardinia Island (Italy) and their antifungal activity.

    abstract::This work reports the results and the comparison concerning the chemical and biomolecular analyses and the antifungal activity of three wild Pistacia species (Anacardiaceae) from Sardinia. Volatile oils from leaves and twigs of Pistacia x saportae, Pistacia lentiscus and Pistacia terebinthus were characterised using G...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1378211

    authors: Marengo A,Piras A,Falconieri D,Porcedda S,Caboni P,Cortis P,Foddis C,Loi C,Gonçalves MJ,Salgueiro L,Maxia A

    更新日期:2018-12-01 00:00:00

  • A new flavonoid glycoside and other chemical constituents from leaves of Rosa davurica and their antioxidant activity.

    abstract::A 70% ethanol extract from the leaves of Rosa davurica showed significant antioxidant activity in both superoxide anion and 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical-scavenging assays. Phytochemical study of this extract resulted in the isolation of eight compounds, including a new flavonoid glycoside. The che...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2013.811408

    authors: Ma F,Onoda T,Li W,Sasaki T,Ma L,Zhang Q,Koike K

    更新日期:2013-01-01 00:00:00

  • Identification and antimicrobial properties of a new alkaloid produced by marine-derived Verrucosispora sp. FIM06-0036.

    abstract::The actinomycete strain FIM06-0036 was isolated from marine sponge sample collected from the East China Sea and identified as Verrucosispora sp. based upon the results of 16S rRNA sequence analysis. One new alkaloid, 2-ethylhexyl 1H-imidazole-4-carboxylate (1), together with a known alkaloid butyl 1H-imidazole-4-carbo...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1689498

    authors: Chen MH,Lian YY,Fang DS,Chen L,Jia J,Zhang WL,Lin R,Xie Y,Bi HK,Jiang H

    更新日期:2019-11-15 00:00:00

  • Urinary metabolites of cinobufagin in rats and their antiproliferative activities.

    abstract::Cinobufagin was one of the important cardenolidal steroids and a major component of Chan'Su, a famous traditional Chinese medicine. The urinary metabolites of cinobufagin after single oral doses of 25 mg kg⁻¹ in rats were investigated. Eleven metabolites were isolated and purified by liquid-liquid extraction, open-col...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2010.510798

    authors: He X,Hu H,Wu Y,Zeng X

    更新日期:2012-01-01 00:00:00

  • Computational studies of Fe(III) binding to bryostatins, bryostatin analogs, siderophores and marine natural products: arguments for ferric complexes in medicinal applications.

    abstract::In this computational study, geometric factors are calculated by applying semi-empirical methods (PM3) that support experimental evidence from this lab where bryostatins can bind trivalent iron with six Fe-O bonds forming an octahedral geometry. The geometric factors are calculated for all 20 structures (Fe3+ bound to...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410701590087

    authors: Manning TJ,Thomas J,Osiro S,Smith J,Abadi G,Noble L,Phillips D

    更新日期:2008-03-20 00:00:00

  • A new iridoid glycoside from the fruits of Vitex rotundifolia.

    abstract::One new iridoid glycoside, 6',10-di-O-(4-hydroxybenzoyl) aucubin (1), together with ten known compounds, including five diterpenoids (2-6), two triterpene glucosides (7-8) and three methoxylated flavonoids (9-11) were isolated from the fruits of Vitex rotundifolia. Compounds (3, 4, 7, and 8) were reported for the firs...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1314284

    authors: Zhao YY,Guo L,Cao LJ,Zhang J,Yin ZQ

    更新日期:2017-11-01 00:00:00

  • X-ray structure analysis of lappaconitine.

    abstract::Lappaconitine is an important alkaloid of the aconite family and its biological activity is closely related to its structure. Through an X-ray structure analysis of hydrated lappaconitine hydrobromide, which was synthesised by us through a new method, the absolute configuration of lappaconitine was determined: monocli...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410902975616

    authors: Sun W,Wang Y,Zhang J,Yu K

    更新日期:2009-01-01 00:00:00

  • Unexpected formation of hydroxybiphenylmethane derivatives and some new observations on Labat test.

    abstract::An unexpected synthesis of symmetrical hydroxybiphenylmethanes involving the reaction of 2-hydroxyphenyl benzyl ketones with ethoxymethyl chloride has been observed. Some new interesting observations of Labat test on colorimetric detection of bichalconyloxy, bichalconyl and biflavonylmethanes having oxygenated ortho p...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410600917902

    authors: Kukreja G,Campiani G,Khurana JM,Joshi BP,Grover SK

    更新日期:2006-10-01 00:00:00

  • 8-O-β-D-Glucopyranosyl-2-methylchromone, a new chromone glycoside from the Tibetan medicine plant of Swertia punicea Hemsl.

    abstract::A new chromone glycoside, 8-O-β-D-Glucopyranosyl-2-methylchromone (1), together with eight known compounds (2-9) were isolated from the Tibetan medicine plant of Swertia punicea. All compounds of this plant were reported for the first time. The structures of these metabolites were elucidated by analysis of their HR-ES...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1777123

    authors: Mou LY,Wei M,Wu HY,Hu LJ,Li JL,Li GP

    更新日期:2020-06-11 00:00:00

  • A novel acridone akaloid from Atalantia buxifolia.

    abstract::Study of the chemical constituents of ethanol extract from the aerial parts of Atalantia buxifolia led to the identification of a new acridone alkaloid named as buxifoliadine (1), along with known compounds citrusinine--I (2), N-methylatalaphylline (3), Severinolid (4) and cycloseverinolide (5). Structural elucidation...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2013.796470

    authors: Shan F,Yin YQ,Huang F,Huang YC,Guo LB,Wu YF

    更新日期:2013-01-01 00:00:00

  • Phenolic profile of hazelnut (Corylus avellana L.) leaves cultivars grown in Portugal.

    abstract::In this study, phenolic compounds of hazelnut leaves of 10 different cultivars with the same cultural, geographical, geological and climatic conditions were analyzed by HPLC/DAD and HPLC/DAD/MS/MS - ESI. Eight phenolic compounds (3-caffeoylquinic acid, 5-caffeoylquinic acid, caffeoyltartaric acid, p-coumaroyltartaric ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410410001704778

    authors: Amaral JS,Ferreres F,Andrade PB,Valentão P,Pinheiro C,Santos A,Seabra R

    更新日期:2005-02-01 00:00:00

  • Evaluation of topical Matricaria chamomilla extract activity on linear incisional wound healing in albino rats.

    abstract::In this investigation, the effect of Matricaria chamomilla extract on linear incisional wound healing was studied. Thirty male Wistar rats were subjected to a linear 3 cm incision made over the skin of the back. The animals were randomly divided into three experimental groups, as control, olive oil, and treatment. Con...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410701654875

    authors: Jarrahi M,Vafaei AA,Taherian AA,Miladi H,Rashidi Pour A

    更新日期:2010-05-01 00:00:00

  • Isoiridomyrmecin rich essential oil from Nepeta erecta Benth. and its antioxidant activity.

    abstract::The essential oil composition of the aerial parts of Nepeta erecta Benth. (Family: Lamiaceae) from Uttarakhand, India was analysed by capillary gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). A total of 34 constituents were identified representing 94.6% of the oil composition. Oxygenated mono...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2010.531393

    authors: Bisht DS,Joshi SC,Padalia RC,Mathela CS

    更新日期:2012-01-01 00:00:00

  • Microwave assisted henna organic dyeing of polyester fabric: a green, economical and energy proficient substitute.

    abstract::The proposed work, aims to provide a "green" and cutting-edge technique for the mordanting and dyeing of polyester fabric with natural henna dye using the advanced technology of micro waves. For providing a complete "green" and ecofriendly dyeing process, lemon was used as a natural bio mordant with micro waves and re...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1619721

    authors: Arain RA,Ahmad F,Khatri Z,Peerzada MH

    更新日期:2021-01-01 00:00:00

  • Polyphenol distribution in plant organs of tomato introgression lines.

    abstract::The content of total polyphenols, chlorogenic, caffeic (CaA) and ferulic acids, and rutin, was investigated in plant organs of three introgression lines (IL7-3, IL10-1 and IL12-4) of Solanum pennellii in Solanum lycopersicum cv M82 and compared with that of cropped parental. Such study aims to evidence factors associa...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2012.704371

    authors: Minutolo M,Amalfitano C,Evidente A,Frusciante L,Errico A

    更新日期:2013-01-01 00:00:00

  • Antioxidant activity and cytotoxicity on tumour cells of the essential oil from Cedronella canariensis var. canariensis (L.) Webb & Berthel. (Lamiaceae).

    abstract::Cedronella canariensis is a lemon-scented species of the family Lamiaceae endemic to the Canary Islands where it is used in the traditional medicine to prepare infusions or inhalations for anti-catarrhal, tonic, diuretic, hypoglycaemiant, hypotensive, anti-inflammatory and decongestant of the respiratory tract. In thi...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.994213

    authors: Zorzetto C,Sánchez-Mateo CC,Rabanal RM,Lupidi G,Bramucci M,Quassinti L,Iannarelli R,Papa F,Maggi F

    更新日期:2015-01-01 00:00:00

  • Two new ent-atisane diterpenoids from the whole plants of Euphorbia wallichii.

    abstract::Two new ent-atisanediterpenoids, ent-atisane-16β, 17-isopropylidenedioxy-19-ol-3-one (1) and ent-atisane-16β, 17-isopropylidenedioxy-11β, 18-dihydroxyl-3-one (2) were isolated from the whole plants of Euphorbia wallichii. Their structures were elucidated on the basis of extensive spectroscopic analyses. ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2016.1250088

    authors: Kuang Y,Fu SY,Wang F,Ren FC,Yang DF,Yang SX,Gao Y

    更新日期:2017-04-01 00:00:00

  • Two new diterpene polyesters from Euphorbia decipiens.

    abstract::Two new myrsinol-type diterpene polyesters 3,5,13,17-tetra-O-acetyl-7-O-benzoyl-15-hydroxymyrsinol (1) and 3,5,13,17-tetra-O-acetyl-7-O-butanoyl-13-hydroxymyrsinol (2), with a tricyclic carbon skeleton have been isolated from Euphorbia decipiens Boiss. & Buhse. The structure elucidation of the isolated compounds was b...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410410001714687

    authors: Ahmad VU,Hussain J,Hussain H,Farooq U,Farmanullah,Lodhi MA,Choudhary MI

    更新日期:2005-04-01 00:00:00

  • Aroma chemical emitted from Gerris paludum insularis.

    abstract::An aroma chemical emitted from Gerris paludum insularis was analyzed by means of GC and GC-MS. The main constituent was identified as iso amyl alcohol (3-methyl-1-butanol). The chemical showed a characteristic aroma of Gerris paludum insularis. ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410310001620655

    authors: Ono T,Miyazawa M

    更新日期:2004-06-01 00:00:00

  • (22E)-Ergosta-6,22-diene-3beta,5alpha,8alpha-triol: a new polyhydroxysterol isolated from Lentinus edodes (Shiitake).

    abstract::From the ethanolic extract of Lentinus edodes (Shiitake) eight known sterols were isolated and identified: ergosterol, ergosterol peroxide, (22E)-ergosta-5,7,9(11), 22-tetraen-3beta-ol, (22E)-ergosta-7,9(11),22-trien-3beta-ol, (22E)-ergosta-6,8,22-trien-3beta-ol, (22E)-norergosta-5,7,9,22-tetraen-3beta-ol, 3beta,5alph...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410802038671

    authors: Rivera A,Benavides OL,Rios-Motta J

    更新日期:2009-01-01 00:00:00

  • Insecticidal and α-glucosidase inhibitory activities of chemical constituents from Viburnum fordiae Hance.

    abstract::The ethanolic extract of the stems of Viburnum fordiae Hance showed insecticidal and α-glucosidase inhibitory activities and then was fractionated by bioactivity-guided fractionation to obtain a rare C13-norisoprenoid (1), together with a new phenolic glycoside (2), and seven known compounds, alangionoside C (3), pisu...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1466130

    authors: Shao JH,Chen J,Zhao CC,Shen J,Liu WY,Gu WY,Li KH

    更新日期:2019-09-01 00:00:00

  • A new 20-membered macrolide produced by a marine-derived Micromonospora strain.

    abstract::A new 20-membered macrolide named as levantilide C was isolated from the Micromonospora strain FIM07-0019 recovered from shallow coastal waters near the island of Chiloe, Chile. The chemical structure of levantilide C was elucidated on the basis of one- and two-dimensional NMR analysis. Two known indole derivatives we...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2012.740038

    authors: Fei P,Chuan-Xi W,Yang X,Hong-Lei J,Lu-Jie C,Uribe P,Bull AT,Goodfellow M,Hong J,Yun-Yang L

    更新日期:2013-08-01 00:00:00

  • One new flavonoid from Solanum rostratum.

    abstract::One new flavonoid, 5,7,8,4'-tetrahydroxy-3-methoxyflavone-8-O-β-d-xylopyranoside (2), along with other four known flavones (1, 3-5) were isolated from the aerial parts of Solanum rostratum. 8-hydroxyflavonoid was isolated from series Androceras for the first time. The structure of the new compound 2 was determined on ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1290621

    authors: Huang HJ,Ling TJ,Wang HM,Cao AC,Zhang CX,Wei SH

    更新日期:2017-08-01 00:00:00

  • A new triterpenoid and other constituents with cytotoxic activity from the roots of Sanguisorba officinalis L.

    abstract::Sanguisorba officinalis L. is a traditional herbal plant that belongs to the genus Sanguisorba and the family Rosaceae. A new ursane-type triterpenoid, 3-oxo-urs-11, 13(18)-dien-19, 28-olide (1), two known ursane-type triterpenoids (3 - 4) and three known oleanane-type triterpenoids (2, 5 - 6) were isolated from the r...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1693569

    authors: Wang R,Sun J,Jin M,Jin L,Qi Y,Cao L,Zhou W,Li G

    更新日期:2019-12-04 00:00:00

  • Semi-synthesis of a novel hybrid isoxazolidino withaferin via chemoselective and diastereoselective 1,3-dipolar nitrone cycloaddition reaction.

    abstract::A facile, atom-economic synthesis of isoxazilidino withaferin, a novel hybrid of withaferin A, has been accomplished via two-step reaction of nitrone synthesis followed by nitrone 1,3-dipolar cycloaddition. The reaction is highly chemoselective (preferential reaction only on one of the two double bonds present on with...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1582045

    authors: Mandal R,Singh M,Krishnan AAV,Dahat YH,Bharitkar YP,Ravichandiran V,Hazra A

    更新日期:2020-08-01 00:00:00

  • A new flavanone glycoside isolated from Tournefortia sibirica.

    abstract::A new flavanone glycoside, (2S)-dihydrooroxylin A 7-O-[β-D-apiosyl(1 → 2)]-β-D-glucoside (1), and four known compounds (2-5) were isolated from Tournefortia sibirica L. The chemical structures of these compounds were determined by 1 D and 2 D NMR and HR-ESI-MS spectra, and r...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1512995

    authors: Diao S,Jin M,Jin CS,Wei CX,Sun J,Zhou W,Li G

    更新日期:2019-10-01 00:00:00