8-O-β-D-Glucopyranosyl-2-methylchromone, a new chromone glycoside from the Tibetan medicine plant of Swertia punicea Hemsl.

Abstract:

:A new chromone glycoside, 8-O-β-D-Glucopyranosyl-2-methylchromone (1), together with eight known compounds (2-9) were isolated from the Tibetan medicine plant of Swertia punicea. All compounds of this plant were reported for the first time. The structures of these metabolites were elucidated by analysis of their HR-ESI-MS, 1D and 2D NMR spectroscopic data and comparison with data reported in the literature. In vitro test, all compounds were evaluated for their anti-inflammatory activity through the determination of nitric oxide production. Compounds 1-2 were evaluated for cytotoxic activities against three human cancer cell lines (HeLa, MDA-MB-231 and A375) by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) method. Furthermore, the chemotaxonomic significance of these compounds has also been described.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Mou LY,Wei M,Wu HY,Hu LJ,Li JL,Li GP

doi

10.1080/14786419.2020.1777123

subject

Has Abstract

pub_date

2020-06-11 00:00:00

pages

1-9

eissn

1478-6419

issn

1478-6427

pub_type

杂志文章
  • Insecticidal activity of the essential oil of Perovskia artemisioides Boiss.

    abstract::This work reports the phytochemical profile and insecticidal properties of Perovskia artemisioides Boiss essential oil (PAEO) collected in Baluchestan, Iran. Totally, twenty-six substances were identified with 1,8-cineole (25.81%), geranyl acetate (13.00%) and linalool (10.21%) as dominant chemical metabolites by GC-M...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1803311

    authors: Sadeghi Z,Alizadeh Z,Khorrami F,Norouzi S,Moridi Farimani M

    更新日期:2020-08-26 00:00:00

  • Insecticidal and α-glucosidase inhibitory activities of chemical constituents from Viburnum fordiae Hance.

    abstract::The ethanolic extract of the stems of Viburnum fordiae Hance showed insecticidal and α-glucosidase inhibitory activities and then was fractionated by bioactivity-guided fractionation to obtain a rare C13-norisoprenoid (1), together with a new phenolic glycoside (2), and seven known compounds, alangionoside C (3), pisu...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1466130

    authors: Shao JH,Chen J,Zhao CC,Shen J,Liu WY,Gu WY,Li KH

    更新日期:2019-09-01 00:00:00

  • A new lignan glycoside from the aerial parts and cytotoxic investigation of Uvaria rufa.

    abstract::Chemical investigation of the aerial parts of Uvaria rufa (Dunal) Blume collected from Vietnam yielded one new lignan glycoside, ufaside (1), along with six known compounds, oxoanolobine (2), ergosta-4,6,8(14),22-tetraen-3-one (3), catechin (4), epicatechin (5), daucosterol (6) and glutin-5-en-3-one (7). Their chemica...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.971790

    authors: Nguyen TH,Ho VD,Do TT,Bui HT,Phan VK,Sak K,Raal A

    更新日期:2015-02-01 00:00:00

  • Two new ent-atisane diterpenoids from the whole plants of Euphorbia wallichii.

    abstract::Two new ent-atisanediterpenoids, ent-atisane-16β, 17-isopropylidenedioxy-19-ol-3-one (1) and ent-atisane-16β, 17-isopropylidenedioxy-11β, 18-dihydroxyl-3-one (2) were isolated from the whole plants of Euphorbia wallichii. Their structures were elucidated on the basis of extensive spectroscopic analyses. ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2016.1250088

    authors: Kuang Y,Fu SY,Wang F,Ren FC,Yang DF,Yang SX,Gao Y

    更新日期:2017-04-01 00:00:00

  • Bacterial production of tetrodotoxin in the pufferfish Arothron hispidus.

    abstract::This study evaluates the presence, location and production source of tetrodotoxin (TTX) in two species of pufferfish, Diodon histrix and Arothron hispidus, common to Hawaiian waters. Organs from each fish were analysed for TTX and used to isolate bacteria for evaluation of possible TTX production. Comparative analyses...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410903003780

    authors: Campbell S,Harada RM,DeFelice SV,Bienfang PK,Li QX

    更新日期:2009-01-01 00:00:00

  • A new xanthone derivative from twigs of Garcinia nobilis.

    abstract::Phytochemical investigation of the twigs of Garcinia nobilis led to the isolation of a new xanthone, named l-hydroxy-2,5-dimethoxyxanthone (1), together with 15 known compounds (2-16). The structures of the new and known compounds were established by means of spectroscopic methods and by comparison with previously rep...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.903398

    authors: Fouotsa H,Tatsimo SJ,Neumann B,Michalek C,Mbazoa CD,Nkengfack AE,Sewald N,Lannang AM

    更新日期:2014-01-01 00:00:00

  • Three alkaloids from Reineckia carnea herba and their antitussive and expectorant activities.

    abstract::Three alkaloids, (3-chloro-2-hydroxypropyl) trimethylammonium chloride (1), p-(acetylamino)-phenol (2) and 4,4'-diacetamidodiphenyl ether (3), were isolated from Reineckia carnea herba. Their structures were determined by detailed analysis of their 1D and 2D NMR spectra and MS. Compounds 1 and 3 were new natural produ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.900618

    authors: Wang J,Han N,Wang Y,Wang Y,Liu Z,Wang Y,Yin J

    更新日期:2014-01-01 00:00:00

  • Phytochemical constituents and in vitro anticancer screening of isolated compounds from Eriocephalus africanus‡.

    abstract::This study investigated the in vitro anticancer potential of phytochemical constituents isolated from the methanolic extract of Eriocephalus africanus. One flavanone (hesperidin) and two flavones (luteolin and apigenin) were isolated for the first time from the plant using column chromatography. Standard MTT assay was...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1744138

    authors: Magura J,Moodley R,Maduray K,Mackraj I

    更新日期:2020-03-25 00:00:00

  • Antibacterial activity of prenylated benzopyrans from Peperomia obtusifolia (Piperaceae).

    abstract::Peperomia obtusifolia is a herbaceous perennial plant native to the Americas reported as a traditional medicine to treat snake bites and as a skin cleanser. The bioassay-guided fractionation of crude extracts from aerial parts of P. obtusifolia against a panel of clinically important fungi and bacteria, showed that he...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1628751

    authors: Ruiz Mostacero N,Castelli MV,Cutró AC,Hollmann A,Batista JM Jr,Furlan M,Valles J,Fulgueira CL,López SN

    更新日期:2019-06-14 00:00:00

  • A new natural nucleotide and other antibacterial metabolites from an endophytic Nocardia sp.

    abstract::Nine compounds were isolated from Nocardia sp. YIM 64630, and their structures were elucidated as 5'-O-acetyl-2'-deoxyuridine (1), 22E,24R-5α,6α-epoxyergosta-8(14),22-diene-3β,7α-diol (2), 22E,24R-5α,6α-epoxyergosta-8,22-diene-3β,7α-diol (3), 22E,24R-ergosta-7,22-diene-3β,5α,6β-triol (4), 5α,8α-epidioxyergosta-6,22-di...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.964713

    authors: Li W,Yang X,Yang Y,Qin S,Li Q,Zhao L,Ding Z

    更新日期:2015-01-01 00:00:00

  • Effects of ethanol extract from Saururus chinensis (Bour.) Baill on lipid and antioxidant metabolisms in rats fed a high-fat diet.

    abstract::This study was performed to investigate the effect of ethanol extract from Saururus chinensis (Lour.) Baill on liver function, plasma lipid composition and antioxidant system with high-fat diet for 4 weeks. Rats were divided into the following five groups; untreated control group (normal), treated with 0.5% SE (normal...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410701590657

    authors: Yu MH,Im HG,Lee JW,Bo MH,Kim HJ,Kim SK,Chung SK,Lee IS

    更新日期:2008-02-15 00:00:00

  • Evaluation of the volatile profile of Tuber liyuanum by HS-SPME with GC-MS.

    abstract::The volatile components of Tuber liyuanum were determined by HS-SPME with GC-MS for the first time. The effects of different fibre coating, extraction time, extraction temperature and sample amount were studied to get optimal extraction conditions. The optimal conditions were SPME fibre of Carboxen/PDMS, extraction ti...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2016.1253082

    authors: Liu C,Li Y

    更新日期:2017-04-01 00:00:00

  • Alkaloids from the fungus Lactarius subplinthogalus.

    abstract::A new alkaloid, namely laccarin A (1), along with four known alkaloids, laccarin (2), adenosine (3), indole-3-carboxaldehyde (4) and nicotinamide (5), was isolated from the fungus Lactarius subplinthogalus. The structure of laccarin A (1) was established mainly by spectroscopic methods. ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410310001608073

    authors: Wang Y,Yang SP,Wu Y,Yue JM

    更新日期:2004-04-01 00:00:00

  • New alkaloids from the leaves of Evodia rutaecarpa.

    abstract::One new indole alkaloid (1) and one new indole alkaloidal glycoside (2), together with nine known alkaloids (3-11), were isolated from the leaves of Evodia rutaecarpa. Their structures were determined on the basis of spectroscopic and chemical methods. Compound 4 exhibited potent activity against Pseudomonas aeruginos...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2016.1146888

    authors: Xia X,Luo JG,Liu RH,Yang MH,Kong LY

    更新日期:2016-10-01 00:00:00

  • A new flavonoid glycoside and other chemical constituents from leaves of Rosa davurica and their antioxidant activity.

    abstract::A 70% ethanol extract from the leaves of Rosa davurica showed significant antioxidant activity in both superoxide anion and 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical-scavenging assays. Phytochemical study of this extract resulted in the isolation of eight compounds, including a new flavonoid glycoside. The che...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2013.811408

    authors: Ma F,Onoda T,Li W,Sasaki T,Ma L,Zhang Q,Koike K

    更新日期:2013-01-01 00:00:00

  • The absolute configuration of anti-Vibrio citrinin dimeric derivative by VCD, ECD and NMR methods.

    abstract::Citrinin dimeric derivatives are bioactive polyketides previously reported from Penicillium, Aspergillus and Monascus fungi species. Due to the large distance between the stereogenic centers of the two monomer units, it was difficult to determine the absolute configuration of the whole molecule (1). In previous work, ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1493590

    authors: Cao F,Sun TT,Yang JK,Zhao GZ,Liu QA,Hu LD,Ma ZY,Zhu HJ

    更新日期:2019-08-01 00:00:00

  • Biological studies of azadirachtin and its derivatives against polyphagous pest, Spodoptera litura.

    abstract::Azadirachtin-A (Aza-A, figure 1) was subjected to a variety of synthetic transformations and the antifeedant activity and toxicity of the azadirachtin derivatives were assessed against second instar larvae Spodoptera litura on castor leaves in comparison with the crude material containing 9.14% Aza-A, as well as relat...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410512331330558

    authors: Deota PT,Upadhyay PR

    更新日期:2005-07-01 00:00:00

  • Antimicrobial activities of essential oil and methanol extract of Coriaria nepalensis.

    abstract::Plant extracts and products have been used for centuries in traditional medicine; for most of them, in addition to the scant scientific credibility, the chemical composition and spectrum of activity are yet to be explored. To put forward this effort and to identify novel antimicrobial agents, the inhibitory activities...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2010.529545

    authors: Kumar P,Bhatt RP,Singh L,Sati OP,Khan A,Ahmad A

    更新日期:2011-07-01 00:00:00

  • The essential oils of the aerial parts of two Hypericum taxa (Hypericum triquetrifolium and Hypericum aviculariifolium subsp. depilatum var. depilatum (Clusiaceae)) from Turkey.

    abstract::In this study, essential oil compositions of two Hypericum L. taxa (Hypericum triquetrifolium Turra. and Hypericum aviculariifolium Jaub. et Spach subsp. depilatum var. depilatum (Freyn et Bornm.) Robson) naturally grown in Turkey were determined using gas chromatography and gas chromatography-mass spectrometry system...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2011.636743

    authors: Yuce E,Bagci E

    更新日期:2012-11-01 00:00:00

  • Cytotoxic cardiac glycosides from the fruit (pods) of Adenium obesum (Forssk.) Roem. & Schult.

    abstract::Phytochemical investigation of methanolic extract of Adenium obesum led to the isolation of 42 (1-42) compounds belongs to cardiac glycosides, triterpenoids and steroids. The chemical structures of isolated compounds were elucidated by spectral techniques UV, IR, NMR and FAB MS. The cardiac glycosides were tested agai...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2016.1226826

    authors: Ahmed SK,Versiani MA,Ikram A,Sattar SA,Faizi S

    更新日期:2017-05-01 00:00:00

  • Comprehensive metabolite profiling in distinct chemotypes of Commiphora wightii.

    abstract::Commiphora wightii (Arn.) Bhandari, known as guggul, produces a medicinally important gum resin which is used extensively by Ayurvedic physicians to treat various ailments. However, most of the studies on C. wightii have been limited to its gum resin. Comprehensive metabolic profiling of leaves, stem and gum resin sam...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1431629

    authors: Bhatia A,Tripathi T,Singh S,Bisht H,Behl HM,Roy R,Sidhu OP

    更新日期:2019-01-01 00:00:00

  • Phenanthrene and dihydrophenanthrene derivatives from Dioscorea communis with anticholinesterase, and antioxidant activities.

    abstract::Five phenanthrene and two dihydrophenanthrene derivatives were isolated from the diethyl ether extract of fresh rhizomes of Dioscorea communis (L.), among them a phenanthrentriol 1 reported for the first time from Dioscoreaceae family and two dihydrophenanthrene derivatives 6 and 7 reported also for the first time fro...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1468328

    authors: Boudjada A,Touil A,Bensouici C,Bendif H,Rhouati S

    更新日期:2019-11-01 00:00:00

  • New asymmetrical bispyrrolidinoindoline diketopiperazines from the marine fungus Aspergillus sp. DX4H.

    abstract::Known diketopiperazine WIN 64821 and its asymmetric stereoisomers (1-3) had been isolated from the culture broth of a marine gut fungus Aspergillus sp. DX4H. The planar and stereochemistry for new compounds were determined by a suite of techniques including mass, NMR and CD spectra together with Marfey's method. Their...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1363752

    authors: Xu J,Hu Q,Ding W,Wang P,Di Y

    更新日期:2018-04-01 00:00:00

  • Phenolic profile of hazelnut (Corylus avellana L.) leaves cultivars grown in Portugal.

    abstract::In this study, phenolic compounds of hazelnut leaves of 10 different cultivars with the same cultural, geographical, geological and climatic conditions were analyzed by HPLC/DAD and HPLC/DAD/MS/MS - ESI. Eight phenolic compounds (3-caffeoylquinic acid, 5-caffeoylquinic acid, caffeoyltartaric acid, p-coumaroyltartaric ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410410001704778

    authors: Amaral JS,Ferreres F,Andrade PB,Valentão P,Pinheiro C,Santos A,Seabra R

    更新日期:2005-02-01 00:00:00

  • A new compound against Peries rapae from Stellera chamaejasme.

    abstract::The ethanol extract of Stellera chamaejasme roots exhibited significant bioactivity against Peries rapae. In the course of a search for the active compounds, S-(+)-1,5-diphenyl-3-hydroxy-1-pentanone (1) was isolated and this compound has never been found before in S. chamaejasme as far as we known. The structure was e...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410701782536

    authors: Liu Q,Jia H,Xiao B,Chen L,Zhou B,Hou TP

    更新日期:2008-03-10 00:00:00

  • A new flavone from Malaysia Borneo Marsdenia tinctoria.

    abstract::Marsdenia tinctoria is an indigo producing plant commonly found in Borneo, Malaysia. In this present study, one new flavone kapitone (1) and three known compounds, that is 3,2'-dihydroxyflavone (2), 1-methylcyclobutene (3) and dimethyl isatoate (4) were isolated from the Malaysia Borneo M. tinctoria R. Br. (Apocynacea...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2015.1118629

    authors: Mohd Nasuha NA,Choo YM

    更新日期:2016-07-01 00:00:00

  • Cytotoxic p-terphenyls from the deep-sea-derived Aspergillus candidus.

    abstract::From the deep-sea-derived fungus Aspergillus candidus, one novel (1) and three known (2-4) p-terphenyl derivates were isolated. The structure of the new compound was established mainly on the basis of extensive analysis of 1D and 2D NMR data. All four isolates were tested for in vitro anti-food allergic and antitumor ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1633651

    authors: Lin YK,Xie CL,Xing CP,Wang BQ,Tian XX,Xia JM,Jia LY,Pan YN,Yang XW

    更新日期:2019-06-24 00:00:00

  • Neolignan and phenylpropanoid compounds from the fruits of Illicium simonsii Maxim.

    abstract::One new sesqui-neolignan compound, namely, sesqui-illisimonan A (1), one new neolignan, illisimonan A (2), and one new phenylpropanoid compound, illisimoid A (3) were isolated from the fruits of Illicium simonsii Maxim. The structures and absolute configurations of these compounds were determined by extensive spectros...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1422179

    authors: Zhuang PY,Chen MH,Wang YN,Wang XX,Feng YJ,Zhang DY

    更新日期:2018-10-01 00:00:00

  • Simultaneous determination of six constituents in Mahuang Fuzi Xixin by UPLC-PDA-MS/MS.

    abstract::Mahuang Fuzi Xixin (MFX), a classic recipe in traditional Chinese medicine, belongs to an exterior-relieving formula. For quality control of the MFX products, qualitative analysis using ultra-high performance liquid chromatography with diode-array detector-tandem mass spectrometry (UPLC-PDA-MS/MS) was undertaken. Six ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.983104

    authors: Zhang L,Wang C,Miao D,Yuan D,Bi K,Yang J,Zhan L

    更新日期:2015-01-01 00:00:00

  • A new furan derivative from an endophytic Aspergillus tubingensis of Decaisnea insignis (Griff.) Hook.f. & Thomson.

    abstract::A new furan derivative named 3-(5-oxo-2,5-dihydrofuran-3-yl) propanoic acid (1) was isolated for the first time. Its structure was elucidated by UV, IR, NMR, HR-ESI-MS and the single-crystal X-ray diffraction spectroscopic data. Meanwhile, the antifungal and antibacterial activities of compound 1 was tested, it exhibi...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1501687

    authors: Yang XF,Wang NN,Kang YF,Ma YM

    更新日期:2019-10-01 00:00:00