Abstract:
:A new chromone glycoside, 8-O-β-D-Glucopyranosyl-2-methylchromone (1), together with eight known compounds (2-9) were isolated from the Tibetan medicine plant of Swertia punicea. All compounds of this plant were reported for the first time. The structures of these metabolites were elucidated by analysis of their HR-ESI-MS, 1D and 2D NMR spectroscopic data and comparison with data reported in the literature. In vitro test, all compounds were evaluated for their anti-inflammatory activity through the determination of nitric oxide production. Compounds 1-2 were evaluated for cytotoxic activities against three human cancer cell lines (HeLa, MDA-MB-231 and A375) by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) method. Furthermore, the chemotaxonomic significance of these compounds has also been described.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Mou LY,Wei M,Wu HY,Hu LJ,Li JL,Li GPdoi
10.1080/14786419.2020.1777123subject
Has Abstractpub_date
2020-06-11 00:00:00pages
1-9eissn
1478-6419issn
1478-6427pub_type
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