Isoiridomyrmecin rich essential oil from Nepeta erecta Benth. and its antioxidant activity.

Abstract:

:The essential oil composition of the aerial parts of Nepeta erecta Benth. (Family: Lamiaceae) from Uttarakhand, India was analysed by capillary gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). A total of 34 constituents were identified representing 94.6% of the oil composition. Oxygenated monoterpenes (74.0%) constituted the major proportion of the oil, dominated by isoiridomyrmecin (70.6%) as a single major constituent. Other significant constituents were caryophyllene oxide (9.6%), β-Bourbonene (2.0%), humulene epoxide II (1.7%) and linalool (1.0%). The in vitro antioxidant activity (AOA) was assessed using β-Carotene bleaching assay, reducing power, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and inhibition of lipid peroxidation methods. The oil was found to exhibit AOA by inhibiting β-Carotene bleaching (54.6 ± 2.52%) and by scavenging DPPH free radical (IC(50) = 0.74 ± 0.12 mg mL(-1)). The AOA of the essential oil of N. erecta and its major compound isoiridomyrmecin has not been reported so far.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Bisht DS,Joshi SC,Padalia RC,Mathela CS

doi

10.1080/14786419.2010.531393

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

29-35

issue

1

eissn

1478-6419

issn

1478-6427

journal_volume

26

pub_type

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