Three new secoiridoid glycosides from the rhizomes and roots of Gentiana scabra and their anti-inflammatory activities.

abstract：:This work reports on the composition and bionutritional value of organic virgin olive oil from the Nocellara del Belice variety, one cultivated in the olive areas of the Sicily region, Italy. Destoned oils obtained by processing olives with a destoning-based procedure were compared with conventional oils. This innovat...

journal_title：Natural product research

authors： Ranalli F,Ranalli A,Contento S,Casanovas M,Antonucci M,Simone GD

更新日期：2013-01-01 00:00:00

abstract：:The crystal structure and unambiguous absolute configuration of meleagrin (1) isolated from fungus Emericella dentata Nq45 is reported herein to first time on the bases of single crystal X-ray diffraction. Together with 1, haenamindole (2), isorugulosuvine (3), secalonic acid D (4), ergosterol (5) and cerebroside A (6...

journal_title：Natural product research

authors： Hamed A,Abdel-Razek AS,Araby M,Abu-Elghait M,El-Hosari DG,Frese M,Soliman HSM,Stammler HG,Sewald N,Shaaban M

更新日期：2020-03-19 00:00:00

abstract：:Synsepalum dulcifificum is an evergreen shrub native of tropical West Africa. It is very effective against a variety of diseases. However, the phytochemical investigation on this plant is limited till now. In our current study, seventeen compounds were isolated and identified from the ethyl acetate extract of the leav...

journal_title：Natural product research

authors： Wang J,Shao S,Huang R,Wu S

更新日期：2020-10-09 00:00:00

abstract：:A new carotenoid glycoside, namely neo-rehmannioside (1), together with five known compounds, 6-O-seco-hydroxyaeginetoyl ajugol (2), oxyrehmaionoside B (3), ajugol (4), geniposidic acid (5) and geniposide (6) was isolated from the 95% ethanol extract of dry roots of Rehmannia glutinosa. The structure of the new compou...

journal_title：Natural product research

authors： Fu GM,Shi SP,Ip FC,Pang HH,Ip NY

更新日期：2011-08-01 00:00:00

abstract：:Microwave assisted Diels-Alder cycloaddition of 5-Br-N-benzylpyridinone (2) with methyl acrylate is described to gain an easy access to 7-bromo-2-benzyl-3-oxo-2-aza-5 or 6-carbomethoxy bicyclo[2.2.2]oct-7-enes (3)-(6). The preparation of the ibogaine analogue 20-desethyl-(20-endo)-hydroxymethyl-11-demethoxyibogaine (1...

journal_title：Natural product research

authors： Passarella D,Barilli A,Efange SM,Elisabetsky E,Leal MB,Lesma G,Linck VM,Mash DC,Martinelli M,Peretto I,Silvani A,Danieli B

更新日期：2006-07-10 00:00:00

abstract：:Two new norsesquiterpenes were isolated from the extracts of the roots and rhizomes of Ligularia lapathifolia (Franch.) Hand.-Mazz. Their structures were identified as 2-acetyl-3a-methyl-5-(2-methyl-but-2-enoyloxy)-3a,4,5,6,7,7a-hexahydro-H-indene-4-carboxylic acid (1) and 2-acetyl-8a-methyl-2-(2-methyl-but-2-enoyloxy...

journal_title：Natural product research

authors： Li YS,Wang ZT,Zhang M,Chen JJ,Luo SD

更新日期：2004-04-01 00:00:00

abstract：:A new bisabolane-type sesquiterpenoid, turmerone Q (1), along with six known compounds (2-7), were isolated from the rhizomes of Curcuma longa L. The structural elucidation of the new compound was conducted using 1H NMR, 13C NMR, HSQC, HMBC and NOESY spectroscopic analyses. The absolute configuration of 1 was elucidat...

journal_title：Natural product research

authors： Yuan T,Zhang C,Qiu C,Xia G,Wang F,Lin B,Li H,Chen L

更新日期：2018-08-01 00:00:00

abstract：:Momordica charantia (family, Cucurbitaceae), commonly known as karela or bitter melon (Japanese name 'Tsurureishi'), is used as a folk medicine in China, the Indian subcontinent and South America. In Chinese traditional medicine, the plant is usually used as a hypoglycaemic and anti-diabetic agent. The hypoglycaemic a...

journal_title：Natural product research

authors： Han C,Hui Q,Wang Y

更新日期：2008-01-01 00:00:00

abstract：:Evaluation of in vitro standard antioxidant assays, such as 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2'-azino-bis-3 ethylbenzothiozoline-6-sulphonic acid diammonium salt (ABTS+) radical scavenging, lipid peroxidation inhibitory (or thiobarbituric acid formation inhibitory activity) and ferrous ion (Fe+2) chelating acti...

journal_title：Natural product research

authors： Chakraborty K,Raola VK

更新日期：2018-11-01 00:00:00

abstract：:Glaucocalyxin A is a natural ent-Kaurane diterpenoid. It has been widely studied for some important biological activities like cytotoxicity and anti-tumour, anti-bacterial, anti-oxidative, anti-coagulative, anti-thrombotic, immune and anti-neuroinflammatory activities. The aim of the present article is to review the a...

journal_title：Natural product research

authors： Xiang Z,Wu X,Liu X,Jin Y

更新日期：2014-01-01 00:00:00

abstract：:Chemical diversity of the essential oils of twenty wild populations of Tanacetum polycephalum Sch. Bip., was investigated. The aerial parts of T. polycephalum were collected at full flowering stage from West Azerbaijan Province of Iran, air-dried; hydrodistilled to produce essential oils. The essential oils were analy...

journal_title：Natural product research

authors： Mojarrad M,Hosseini Sarghein S,Sonboli A

更新日期：2019-05-01 00:00:00

abstract：:The chemical composition of the methanol extract obtained from Araucaria cunninghamii Sweet. bark was determined by GC-MS analysis with its antioxidant and antibacterial potential, for the first time. A total of 73 compounds were identified and the extract was strongly characterised by Viridiflorene; Androstan-17-one,...

journal_title：Natural product research

authors： Kumar P,Sati SC,Khulbe K,Pant P,Tripathi AN,Sarvendra K

更新日期：2020-11-29 00:00:00

abstract：:Two new iridoids namely valerialloside A and valerianoside A (1 and 2) along with five known compounds (3-7) were isolated from the roots of Valeriana jatamansi Jones. The structure of new compounds were determined using 1D and 2D NMR including 1H-1H COSY, HSQC, HMBC and NOESY spectroscopic techniques. ...

journal_title：Natural product research

authors： Maurya AK,Kumar A,Agnihotri VK

更新日期：2020-12-09 00:00:00

abstract：:Two diketopiperazines were isolated from a culture of the marine-derived actinomycete Streptomyces sp. ZZ446. Their structures were elucidated as maculosin (1) and maculosin-O-α-L-rhamnopyranoside (2) based on their NMR and HRESIMS data, specific rotation, and chemical degradation. Maculosin-O-α-L-rhamnopyranoside (2)...

journal_title：Natural product research

authors： Chen S,Zhang D,Chen M,Zhang Z,Lian XY

更新日期：2020-04-01 00:00:00

abstract：:The chemical constituents identified in the essential oils hydrodistilled from the leaves of Amomum gagnepainii T.L.Wu, K.Larsen and Turland and Amomum repoense Pierre ex Gagnep (Zingiberaceae) of Vietnam origin are reported. The chemical analyses were performed by means of gas chromatography-flame ionisation detector...

journal_title：Natural product research

authors： Huong LT,Hung NV,Chung MV,Dai DN,Ogunwande IA

更新日期：2018-02-01 00:00:00

abstract：:Fermentation of (+)-androst-4-ene-3,17-dione (1) with Curvularia lunata for 10 days yielded five oxidative and reductive metabolites, androsta-1,4-diene-3,17-dione (2), 17beta-hydroxyandrosta-1,4-dien-3-one (3), 11alpha-hydroxyandrost-4-ene-3,17-dione (4), 11alpha,17beta-dihydroxyandrost-4-en-3-one (5) and 15alpha-hyd...

journal_title：Natural product research

authors： Choudhary MI,Sultan S,Khan MT,Yasin A,Shaheen F,Atta-ur-Rahman

更新日期：2004-12-01 00:00:00

abstract：:The biological properties of medicinal plants have been documented worldwide for many centuries. We aimed to evaluate interactions between crude extracts from Psidium guajava, Zingiber officinale, Cymbopogon citratus, Caryophyllus aromaticus, Mikania glomerata and Allium sativum samples and antimicrobial drugs against...

journal_title：Natural product research

authors： Ushimaru PI,Barbosa LN,Fernandes AA,Di Stasi LC,Fernandes A Jr

更新日期：2012-01-01 00:00:00

abstract：:Present research reports the molecular docking analysis of 2019-nCoV inhibition by antiviral compounds from marine natural resources. For this study, the structure of ligand (antiviral compound) and 2019-nCoV main protease (Mpro) was received from the databases of PubChem and Protein Data Bank (PDB), respectively. Mol...

journal_title：Natural product research

authors： Vijayaraj R,Altaff K,Rosita AS,Ramadevi S,Revathy J

更新日期：2020-07-09 00:00:00

abstract：:This study was designed to investigate possible antidepressant-like effects of the extract prepared from the flowers of Hypericum montbretti Spach. (Guttiferae, Clusiaceae). Phytochemical constituents of the methanolic extract were analysed by HPLC method. The main flavonoid component was detected as rutin, and anothe...

journal_title：Natural product research

authors： Can OD,Ismail IB,Oztürk Y,Oztürk N,Potoğlu-Erkara I,Sagratini G,Ricciutelli M,Vittori S,Maggi F

更新日期：2011-09-01 00:00:00

abstract：:The aim of the present study was to study the effect of seeds of Asteracantha longifolia on the sexual behaviour of male albino rats. The ethanolic extract of seeds of A. longifolia was administered to groups of rats in 100, 150 and 200 mg kg⁻¹ doses for a period of 28 days, and the action compared with control rats. ...

journal_title：Natural product research

authors： Chauhan NS,Sharma V,Dixit VK

更新日期：2011-09-01 00:00:00

abstract：:Two new benzoic acid derivatives, named methyl(S)-3-hydroxy-4-(2- hydroxy -6-methylheptan-2-yl)benzoate (1) and 2-hydroxy-3-(6- hydroxy-6-methylhept-1-en-2-yl)benzoic acid (2), were isolated from the ethanol extract of an endophytic fungus Aspergillus versicolor derived from the medicinal plant Euphorbia royleana. The...

journal_title：Natural product research

authors： Ye Y,Chen Y,Hou Y,Yu H,Zhu L,Sun Y,Zhou M,Chen Y,Dong M

更新日期：2020-06-11 00:00:00

abstract：:Oxygen radical absorbance capacity (ORAC) is a widely used hydrogen atom transfer-based method which measures the antioxidant capacity of natural products. ORAC values of oleaster (Elaeagnus angustifolia L.), which was extracted with ethanol/acetone (7:3, v/v), ethanol/water (1:1, v/v) and methanol/water (1:1, v/v) in...

journal_title：Natural product research

authors： Yalcin G,Sogut O

更新日期：2014-01-01 00:00:00

abstract：:Formulations of traditional medicines are usually made up of a complex mixture of herbs. However, effective quality control methods in order to select materials of the right quality are lacking. 'Amukkara choornam' is a polyherbal Siddha formulation used for gastritis, spleen enlargement, leucorrhoea, hiccups, anaemia...

journal_title：Natural product research

authors： Patra KC,Singh B,Pareta S,Kumar KJ

更新日期：2010-12-01 00:00:00

abstract：:Aim of the present study was to evaluate the potential beneficial and/or adverse effects of Capsicum annuum L. (cv. Fiesta) extracts at two stage of ripening (immature and mature), and at two dosages (low and high) by evaluation of biochemical profile and oxidative status in CD-1 mice. The extracts were daily administ...

journal_title：Natural product research

authors： Morittu VM,Pero ME,Musco N,Mastellone V,Tudisco R,Provenzano E,Britti D,Menichini F,Infascelli F,Lombardi P

更新日期：2020-06-01 00:00:00

abstract：:Triterpene saponins in medicinal plants attract scientific attentions for their structural diversity and significant bioactivities. In this work, a high-performance liquid chromatography coupled to electrospray ionisation and quadrupole time-of-flight mass spectrometry (HPLC-ESI-QTOF-MS/MS) method is used to rapidly s...

journal_title：Natural product research

authors： Zhang EF,Ling Y,Yin Z,Zhang Q

更新日期：2018-04-01 00:00:00

abstract：:Polyphyllin Ι is a steroidal saponin isolated from the rhizoma of Paris polyphylla. In the present study, we aimed to investigate the anticancer effects of polyphyllin Ι in colorectal cancer and to elucidate the potential underlying molecular mechanisms. Using, CCK8 assay, flow cytometry, laser confocal microscope ana...

journal_title：Natural product research

authors： Yu S,Wang L,Cao Z,Gong D,Liang Q,Chen H,Fu H,Wang W,Tang X,Xie Z,He Y,Peng C,Li Y

更新日期：2018-06-01 00:00:00

abstract：:Thirty semicarbazone and thiosemicarbazone derivatives (2a-w and 4a-g) from chalcones containing furan and thiophene ring were designed and synthesized. They were characterized by IR, 1H NMR, 13C NMR and HRMS. The crystal structure of compound 2r was characterized by single crystal X-ray diffraction. It crystallizes i...

journal_title：Natural product research

authors： Cheng W,Xiao T,Qian W,Lu T,Zhang T,Tang X

更新日期：2020-03-16 00:00:00

abstract：:A new xanthone, calothorexanthone, together with five known compounds, garbogiol, 1,4,8-trihydroxyxanthone, δ-tocotrienol, 1,7-dihydroxyxanthone and globuxanthone, was isolated from a petroleum ether extract of the bark of Calophyllum thorelii. Their structures were established on the basis of spectroscopic methods, m...

journal_title：Natural product research

authors： Nguyen LT,Nguyen DM,Nguyen LH

更新日期：2013-01-01 00:00:00

abstract：:In the present study, evaluation of the antiproliferative activity of Pachypodium lamerei Drake leaves (family Apocyaceae) against human breast cancer cell lines MDA-MB-231 was done for the total methanolic extract, crude alkaloidal mixture and ursolic acid using the MTT colorimetric assay. The methanolic extract show...

journal_title：Natural product research

authors： Mina SA,Mohamed SA,Melek FR,Abd El-Khalik SM

更新日期：2020-05-01 00:00:00

abstract：:Antioxidant, anticholinesterase and antidiabetic activities of three curcuminoids isolated from the Curcuma longa were simultaneously tested and compared in this study. The highest antioxidant power was detected for curcumin with the applied methods. The drug potentials of curcuminoids for Alzheimer's disease were con...

journal_title：Natural product research

authors： Kalaycıoğlu Z,Gazioğlu I,Erim FB

更新日期：2017-12-01 00:00:00