Abstract:
:A new bisabolane-type sesquiterpenoid, turmerone Q (1), along with six known compounds (2-7), were isolated from the rhizomes of Curcuma longa L. The structural elucidation of the new compound was conducted using 1H NMR, 13C NMR, HSQC, HMBC and NOESY spectroscopic analyses. The absolute configuration of 1 was elucidated by comparison of the experimental and calculated ECD spectra. The anti-inflammatory effects of 1-7 were evaluated through lipopolysaccharide-induced nitric oxide (NO) production in RAW 264.7 macrophages assays, and compounds 6 and 7 showed potent inhibitory activity against NO production.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Yuan T,Zhang C,Qiu C,Xia G,Wang F,Lin B,Li H,Chen Ldoi
10.1080/14786419.2017.1354185subject
Has Abstractpub_date
2018-08-01 00:00:00pages
1887-1892issue
16eissn
1478-6419issn
1478-6427journal_volume
32pub_type
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