Evaluation of the antiviral and antimicrobial activities of triterpenes isolated from Euphorbia segetalis.

abstract：:A new prenylated indole alkaloid, named paraherquamide J (1), together with four known compounds (2-5), were isolated from the mangrove rhizosphere soil-derived fungus Penicillium janthinellum HK1-6. The planar structure and relative configuration of 1 were determined by detailed analysis of the spectroscopic data esp...

journal_title：Natural product research

authors： Zheng YY,Shen NX,Liang ZY,Shen L,Chen M,Wang CY

更新日期：2020-02-01 00:00:00

abstract：:The hexane and ethanol extracts from Himatanthus bracteatus (Apocynaceae) stems were evaluated for antiviral activity against Zika virus, yellow fever virus and dengue virus 2 and for cytotoxicity in Vero cells by MTT assay. The ethanol extract showed good antiviral activity against the three viruses with selective in...

journal_title：Natural product research

authors： da Silva ML,Stehmann JR,Serafim MSM,Vale VV,Gontijo DC,Brandão GC,Kroon EG,de Oliveira AB

更新日期：2019-11-20 00:00:00

abstract：:Several factors affect the vegetative growth of fungi, such as temperature, pH, and culture medium. In addition to mycelial growth, these factors affect metabolite production. There are limited studies that have identified the metabolites produced by the fungus Bjerkandera adusta, which have potential biotechnological...

journal_title：Natural product research

authors： Rech KS,de Oliveira CF,Moura PF,de Oliveira CDSP,Hirota BCK,de Oliveira M,Rüdiger AL,de Sá EL,Miguel OG,Auer CG,Miguel MD

更新日期：2020-05-06 00:00:00

abstract：:Sahandinone (1), 12-deoxysalvipisone (2), miltirone (3), 7α-acetoxyroyleanone (4), and labda-7,14-dien-13-ol (5) were isolated from the roots of Salvia rhytidea Benth. (Lamiaceae). Their structures were elucidated by a combination of spectroscopic analyses including EIMS and NMR. The 13C NMR spectroscopic data were re...

journal_title：Natural product research

authors： Jassbi AR,Eghtesadi F,Hazeri N,Ma'sumi H,Valizadeh J,Chandran JN,Schneider B,Baldwin IT

更新日期：2017-02-01 00:00:00

abstract：:Using a bioactivity-guided fractionation procedure, five cembranolides, 11-epi-sinulariolide acetate (1), 11-dehydrosinulariolide (2), sinulariolide (3), dihydrosinularin (4), and 3,4:8,11-bisepoxy-7-acetoxycembra-15(17)-en-1,12-olide (5), along with two nucleosides, 2'-deoxyadenosine and thymidine, were isolated from...

journal_title：Natural product research

authors： Hsieh PW,Chang FR,McPhail AT,Lee KH,Wu YC

更新日期：2003-12-01 00:00:00

abstract：:Fermentation of (+)-androst-4-ene-3,17-dione (1) with Curvularia lunata for 10 days yielded five oxidative and reductive metabolites, androsta-1,4-diene-3,17-dione (2), 17beta-hydroxyandrosta-1,4-dien-3-one (3), 11alpha-hydroxyandrost-4-ene-3,17-dione (4), 11alpha,17beta-dihydroxyandrost-4-en-3-one (5) and 15alpha-hyd...

journal_title：Natural product research

authors： Choudhary MI,Sultan S,Khan MT,Yasin A,Shaheen F,Atta-ur-Rahman

更新日期：2004-12-01 00:00:00

abstract：:Three compounds, toosendanin (1), kulactone (2) and scopoletin (3), were isolated from either the root bark and/or the stem bark of Melia volkensii. Their structures were determined on the basis of spectroscopic data generated and by comparison with data from the literature. 1 and 2, isolated for the first time from M...

journal_title：Natural product research

authors： Kamau RW,Juma BF,Baraza LD

更新日期：2016-09-01 00:00:00

abstract：:A new phenol glycoside, physanguloside A (1), was isolated from Physalis angulata together with four known compounds. We report herein, for the first time, the presence of compounds 2-5 in the genus Physalis. The structures of all the compounds were established by NMR, IR, UV and HRESIMS spectroscopic analyses, and co...

journal_title：Natural product research

authors： Sun CP,Nie XF,Kang N,Zhao F,Chen LX,Qiu F

更新日期：2017-05-01 00:00:00

abstract：:A new isoflavonoid, excelsanone (2), was isolated from the ethyl acetate extract of Erythrina excelsa stem bark, together with three known compounds namely 6,8-diprenylgenistein (3), β-sitosterol (1) and sitosteryl-β-D-glucopyranoside (4). Their structures were elucidated using spectroscopic methods (HR-ESI-MS, NMR an...

journal_title：Natural product research

authors： Gbaweng AJY,Daïrou H,Zingué S,Emmanuel T,Tchinda AT,Frédérich M,Mbafor JT

更新日期：2020-03-01 00:00:00

abstract：:Comparison of an authentic sample of altertenuol with altenuisol obtained by total synthesis and analysis of nuclear magnetic resonance spectra unambiguously revealed that altertenuol and altenuisol are identical compounds. ...

journal_title：Natural product research

authors： Thomas R,Nemecek G,Podlech J

更新日期：2013-01-01 00:00:00

abstract：:The ethanol extract of Stellera chamaejasme roots exhibited significant bioactivity against Peries rapae. In the course of a search for the active compounds, S-(+)-1,5-diphenyl-3-hydroxy-1-pentanone (1) was isolated and this compound has never been found before in S. chamaejasme as far as we known. The structure was e...

journal_title：Natural product research

authors： Liu Q,Jia H,Xiao B,Chen L,Zhou B,Hou TP

更新日期：2008-03-10 00:00:00

abstract：:In situ generation of hydrogen iodide from cesium iodide/methanesulfonic acid was found to be an attractive reagent combination for the conversion of alkyl, allyl, and benzyl alcohols to their corresponding iodides under mild conditions. The method is compared with that using cesium iodide/p-toluenesulfonic acid or ce...

journal_title：Natural product research

authors： Khan KM,Zia-Ullah,Perveen S,Hayat S,Ali M,Voelter W

更新日期：2008-01-01 00:00:00

abstract：:A total of 25 compounds including terpenoids, flavonoids, biflavonoids and ginkgolic acids were identified and quantified with a reliable, simple, and simultaneous method from Ginkgo leaves, seed coats and embryoids with different tree ages (approximately identified as 25, 500, 1000 and 2000 years). Leaves had the hig...

journal_title：Natural product research

authors： Chen X,Zhong W,Shu C,Yang H,Li E

更新日期：2020-07-01 00:00:00

abstract：:As part of our continuing efforts to explore bioactive compounds from natural resources, a new iridoid glycoside, adoxosidic acid-6'-oleuroperic ester (1), together with one known phenylethanoid glycoside (2) and two known flavonoid glycosides (3-4) were isolated from the fruit of Forsythia suspensa. The structure of ...

journal_title：Natural product research

authors： Wei Q,Zhang R,Wang Q,Yan XJ,Yu QW,Yan FX,Li C,Pei YH

更新日期：2020-05-01 00:00:00

abstract：:Phebaclavin I, a novel 3-prenylated coumarin, was isolated from the aerial parts of Phebalium aff. tuberculosum (Rutaceae) together with five known related compounds, Phebaclavin A, B, D, G, H. The structure of phebaclavin I was established by spectroscopic methods. Several other known coumarins were obtained, includi...

journal_title：Natural product research

authors： Roux D,Muyard F,Girard C,Colombain M,Tillequin F,Waterman PG,Bévalot F

更新日期：2006-03-01 00:00:00

abstract：:A new 5-O-beta-D-glucopyranosyl-4-(4-hydroxyphenyl)-7-methoxy-2H-chromen-2-one (1), together with four known compounds, one coumarin, 5-O-beta-D-galactopyranosyl-4-(4-hydroxyphenyl)-7-methoxy-2H-chromen-2-one (2) and three cucurbitacins, 23,24-dihydrocucurbitacin F (3), 23,24-dihydro-25-acetylcucurbitacin F (4) and 2-...

journal_title：Natural product research

authors： Olmedo D,Rodríguez N,Vásquez Y,Solís PN,López-Pérez JL,Feliciano AS,Gupta MP

更新日期：2007-06-01 00:00:00

abstract：:A new protostane-type triterpenoid bearing an oxetane ring in the side-chain, named alisol W (1), has been obtained from the dried rhizome of Alisma plantago-aquatica subsp. orientale. The structure and absolute configuration of compound 1 was determined from extensive spectroscopic analysis. In addition, the vasorela...

journal_title：Natural product research

authors： Li HM,Liu D,Dai WF,Chen XQ,Li RT

更新日期：2019-11-01 00:00:00

abstract：:Two new flavonoids, 8-hydroxyisoscoparin (1) and luteolin 7-O-glucoside 4''-sulfate (2), along with eight known flavonoids, including luteolin 7-O-glucoside 2''-sulfate, were isolated and identified from Washingtonia filifera. All compounds were characterized by (1)H-NMR, (13)C-NMR, CI-MS, FABMS and UV. The antioxidan...

journal_title：Natural product research

authors： El-Sayed NH,Ammar NM,Al-Okbi SY,El-Kassem LT,Mabry TJ

更新日期：2006-01-01 00:00:00

abstract：:Phytochemical investigation of methanolic extract of Adenium obesum led to the isolation of 42 (1-42) compounds belongs to cardiac glycosides, triterpenoids and steroids. The chemical structures of isolated compounds were elucidated by spectral techniques UV, IR, NMR and FAB MS. The cardiac glycosides were tested agai...

journal_title：Natural product research

authors： Ahmed SK,Versiani MA,Ikram A,Sattar SA,Faizi S

更新日期：2017-05-01 00:00:00

abstract：:The methanolic extract of the Tanacetum gracile afforded the isolation of new sesquiterpene lactone, named gracilone (1) along with four known compounds as 14α-taraxeran-3-one (2), 14α-taraxeran-3-ol (3), apigenin (4) and β-sitosterol (5). The structure of compound 1 was elucidated on the basis of 1D, 2D NMR and MS sp...

journal_title：Natural product research

authors： Bhat G,Masood A,Ganai BA,Hamza B,Ganie S,Shafi T,Idris A,Shawl AS,Tantry MA

更新日期：2016-10-01 00:00:00

abstract：:Peperomia obtusifolia is a herbaceous perennial plant native to the Americas reported as a traditional medicine to treat snake bites and as a skin cleanser. The bioassay-guided fractionation of crude extracts from aerial parts of P. obtusifolia against a panel of clinically important fungi and bacteria, showed that he...

journal_title：Natural product research

authors： Ruiz Mostacero N,Castelli MV,Cutró AC,Hollmann A,Batista JM Jr,Furlan M,Valles J,Fulgueira CL,López SN

更新日期：2019-06-14 00:00:00

abstract：:Chemical investigation of the lichen Parmotrema dilatatum led to the isolation of a new chlorinated compound, named dilatatone (1), along with a known compound, sernanderin (2). Their chemical structures were determined by analysis of their 1 D and 2 D NMR spectra, HRESIMS, and ECD data. Both compounds showed weak α-g...

journal_title：Natural product research

authors： Phan HV,Devi AP,Le HD,Nguyen TT,Nguyen HH,Le TT,Nguyen TH,Sichaem J,Duong TH

更新日期：2020-01-27 00:00:00

abstract：:In this study the antioxidant and cytotoxicity activity of the Adonidia merrillii fruits were investigated using different solvent polarities (methanol, ethyl acetate and water). The results showed that the total phenolic and flavonoid contents of the methanolic extract was higher compare with other extract with respe...

journal_title：Natural product research

authors： Vafaei A,Bin Mohamad J,Karimi E

更新日期：2019-09-01 00:00:00

abstract：:Phytochemical investigation of Strychnos nitida has led to the isolation of three new racemic pyridocarbazole alkaloids, (±)-stritidas A-C (1-3) and three known monoterpenoid indole alkaloids (4-6). Compounds 2 and 3 represent the first examples of pyridocarbazole alkaloids featuring an N-2-hydroxyethyl moiety. Their ...

journal_title：Natural product research

authors： Li W,Tang GH,Chen L,Tang YQ,Xu YK,Liu B,Yin S

更新日期：2018-07-01 00:00:00

abstract：:Bioactivity guided fractionation of Echiochilon fruticosum Desf. (Boraginaceae) butanolic extract biautography assay against fungi led to the isolation of a new bioactive alkaloid, named saoussanabiloïde (1). Its structure was established on the basis of spectroscopic measurements, IR, MS and 2D NMR using COSY, HMQC a...

journal_title：Natural product research

authors： Hammami S,Mighri N,Ben Jannet H,Boughalleb N,Zardi-Bergaoui A,Nefzi A,Abreu P,Mighri Z

更新日期：2009-01-01 00:00:00

abstract：:The brown seaweed, Sargassum linearifolium (Turner) C. Agardh, 1820 is commonly available along the south-east coast of India. Its compound fucosterol was isolated and confirmed through spectral characterisation and chemical transformation methods. The antiplasmodial effect of the isolated fucosterol was investigated ...

journal_title：Natural product research

authors： Perumal P,Sowmiya R,Prasanna Kumar S,Ravikumar S,Deepak P,Balasubramani G

更新日期：2018-06-01 00:00:00

abstract：:Chemical investigation of the root bark of Morus alba led to the isolation of a new flavone, dioxycudraflavone A (1) and a new 2-arylbenzofuran, 5-hydroxyethyl moracin M (2), together with seven known compounds namely sanggenon V (3), morusin (4), morusignin L (5), licoflavone C (6), moracin C (7), alfafuran (8) and m...

journal_title：Natural product research

authors： Li M,Wu X,Wang X,Shen T,Ren D

更新日期：2018-01-01 00:00:00

abstract：:A screening of Chinese medicinal herbs and wild plants for agrochemicals was carried out; the essential oil of Glycosmis lucida leaves was found to possess significant repellent activity against Tribolium castaneum and Liposcelis bostrychophila. It was found that the main components included elixene (19.81%), spathule...

journal_title：Natural product research

authors： Guo SS,Zhang WJ,Yang K,Liang JY,You CX,Wang CF,Li YP,Geng ZF,Deng ZW,Du SS

更新日期：2017-05-01 00:00:00

abstract：:This study investigated the flavonoid constituents of a traditional Chinese medical plant Ziziphora clinopodioides Lam. by using ultra-performance liquid chromatography coupled with quadruple time-of-flight mass spectrometry and screened the active components in regulating autophagy.Normal rat kidney (NRK) cells trans...

journal_title：Natural product research

authors： Zhang XM,An DQ,Guo LL,Yang NH,Zhang H

更新日期：2019-09-01 00:00:00

abstract：:(+)-7-O-Methylisomiroestrol (MeI), a novel chromene, was discovered as a phytoestrogen in the Pueraria candollei var. mirifica (Airy Shaw & Suvat.) Niyomdham (PM) root having been used as an active agent against oestrogen depletion disorders. The identification of PM phytochemicals is crucial for the development of st...

journal_title：Natural product research

authors： Yusakul G,Juengsanguanpornsuk W,Sritularak B,Phaisan S,Juengwatanatrakul T,Putalun W

更新日期：2020-02-20 00:00:00