A new C20-diterpenoid alkaloid from Aconitum soongaricum var. pubescens.

Abstract:

:A new denudatine-type C20-diterpenoid alkaloid, pubesine (1), along with seven known diterpenoid alkaloids, altaconitine (2), 14-benzoylaconine (3), spicatine A (4), 14-benzoylaconine-8-palmitate (5), 14-O-acetylsenbusine A (6), senbusine A (7) and 14-acetylneoline (8) were isolated from the whole plant of Aconitum soongaricum var. pubescens. Their structures were elucidated by means of extensive spectroscopic analyses (NMR and HR-ESI-MS) and comparison with data reported in the literature. All compounds were evaluated for their cytotoxicity against H460, MCF-7 and Hep G2 human cancer cell lines.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Chen L,Shan L,Xu W,Zhang J,Huang S,Zhou X

doi

10.1080/14786419.2016.1198348

subject

Has Abstract

pub_date

2017-03-01 00:00:00

pages

523-528

issue

5

eissn

1478-6419

issn

1478-6427

journal_volume

31

pub_type

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