Abstract:
:A new denudatine-type C20-diterpenoid alkaloid, pubesine (1), along with seven known diterpenoid alkaloids, altaconitine (2), 14-benzoylaconine (3), spicatine A (4), 14-benzoylaconine-8-palmitate (5), 14-O-acetylsenbusine A (6), senbusine A (7) and 14-acetylneoline (8) were isolated from the whole plant of Aconitum soongaricum var. pubescens. Their structures were elucidated by means of extensive spectroscopic analyses (NMR and HR-ESI-MS) and comparison with data reported in the literature. All compounds were evaluated for their cytotoxicity against H460, MCF-7 and Hep G2 human cancer cell lines.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Chen L,Shan L,Xu W,Zhang J,Huang S,Zhou Xdoi
10.1080/14786419.2016.1198348subject
Has Abstractpub_date
2017-03-01 00:00:00pages
523-528issue
5eissn
1478-6419issn
1478-6427journal_volume
31pub_type
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