Terpenoids and phenolics from Plectranthus strigosus, bioactivity screening.

abstract：:In the present study, the chemical composition of the essential oil from the aerial parts of Anthemis secundiramea Biv. subsp. secundiramea L. collected in Sicily was evaluated by GC and gas chromatography-mass spectrometry. The main components of A. secundiramea were (Z)-lyratyl acetate (14.6%), (Z)-chrysanthenyl ace...

journal_title：Natural product research

authors： Casiglia S,Bruno M,Senatore F,Rosselli S

更新日期：2019-04-01 00:00:00

abstract：:From the fruiting body of ectomycorrhizal fungi Cortinarius xiphidipus, sterols were identified from the crude extract and the cytotoxic effect of ergosta-4, 6, 8(14), 22-tetraen-3-one (ergone) was evaluated. Ten sterols including ergosta-3,5,7,9(11),22-pentaene, (22E)-ergosta-5,7,9(11),22-tetraen-3b-ol, (3β,22E)-ergo...

journal_title：Natural product research

authors： Torres S,Cajas D,Palfner G,Astuya A,Aballay A,Pérez C,Hernández V,Becerra J

更新日期：2017-02-01 00:00:00

abstract：:4-Methoxybenzene-1-ONN-azoxyformamide (1), 4-methoxybenzene-1-azoformamide (2), 4-hydroxyben-zene-1-azoformamide (3) and 4-hydroxybenzene-1-ONN-azoxyformamide (4) were isolated from the fruiting bodies of Calvatia craniiformis and Lycoperdon hiemale, respectively. Compounds 1 and 4 showed radicle growth inhibitory act...

journal_title：Natural product research

authors： Kamo T,Kashiwabara M,Tanaka K,Ando S,Shibata H,Hirota M

更新日期：2006-05-10 00:00:00

abstract：:This study describes the in vitro inhibition of protein denaturation of extract/fractions of Withania somnifera and isolated withanolides including 20β hydroxy-1-oxo(22R)-witha-2,5,24 trienolide (1), (20R,22R-14α,20α)-dihydroxy-1-oxowitha-2,5,16,24 tetraenolide (2). The results showed that the extract/fractions of the...

journal_title：Natural product research

authors： Khan MA,Khan H,Rauf A,Ben Hadda T

更新日期：2015-01-01 00:00:00

abstract：:Hechtia glomerata, a Mexican medicinal plant employed against bacterial infections and as food, is taxonomically related to the genus Tillandsia which has anticancer activity. Organic and aqueous extracts of H. glomerata leaves were prepared and tested for cytotoxic and antibacterial activity. UPLC-QTOF-MS analysis de...

journal_title：Natural product research

authors： Stefani T,Morales-San Claudio PDC,Rios MY,Aguilar-Guadarrama AB,González-Maya L,Sánchez-Carranza JN,González-Ferrara M,Camacho-Corona MDR

更新日期：2020-07-16 00:00:00

abstract：:A new chromone glycoside, 8-O-β-D-Glucopyranosyl-2-methylchromone (1), together with eight known compounds (2-9) were isolated from the Tibetan medicine plant of Swertia punicea. All compounds of this plant were reported for the first time. The structures of these metabolites were elucidated by analysis of their HR-ES...

journal_title：Natural product research

authors： Mou LY,Wei M,Wu HY,Hu LJ,Li JL,Li GP

更新日期：2020-06-11 00:00:00

abstract：:Two new fatty acid esters of triterpenoids (1-2) together with eleven known compounds (3-13) were obtained after investigation of the CH2Cl2-MeOH (1:1) crude extract from the leaves of Schefflera barteri Harms. All these compounds (1-13) were isolated for the first time from this plant among which compounds 3, 4, 6 an...

journal_title：Natural product research

authors： Mbougnia JFT,Bitchagno GTM,Wouamba SCN,Jouda JB,Awouafack MD,Tene M,Lenta BN,Kouam SF,Tane P,Sewald N

更新日期：2020-11-18 00:00:00

abstract：:Four C-13, C-14 side chain modified 9(R)-hydroxy-1-deoxy-taxane analogues 15, 16, 19 and 22 were semi-synthesized from 1-deoxybaccatin VI. The in vitro antitumor activity of these compounds was evaluated against A549 and A2780 cell lines. The preliminary SAR analysis showed that introduction of oxygen-containing group...

journal_title：Natural product research

authors： Tang P,Lin HX,Yuan TH,Cui YM

更新日期：2019-12-01 00:00:00

abstract：:Investigation on the leaves of Melicope bonwickii (F.Muell.) T.Hartley (Rutaceae) afforded a new 7-(2'-hydroxy-3'-chloroprenyloxy)-4-methoxyfuroquinoline (1) together with the known 7-(2',3'-epoxyprenyloxy)-4-methoxyfuroquinoline (2), evellerine (3) kokusaginine (4) and an amide aurantiamide acetate (5). Compounds 1 a...

journal_title：Natural product research

authors： Komala I,Rahmani M,Sukari MA,Mohd Ismail HB,Cheng Lian GE,Rahmat A

更新日期：2006-04-01 00:00:00

abstract：:A new alkaloid, namely laccarin A (1), along with four known alkaloids, laccarin (2), adenosine (3), indole-3-carboxaldehyde (4) and nicotinamide (5), was isolated from the fungus Lactarius subplinthogalus. The structure of laccarin A (1) was established mainly by spectroscopic methods. ...

journal_title：Natural product research

authors： Wang Y,Yang SP,Wu Y,Yue JM

更新日期：2004-04-01 00:00:00

abstract：:Benign prostatic hypertrophy (BPH) is a common condition in elderly men that impairs quality of life and leads to a number of medical complications. The use of phytotherapeutic compounds in patients with relatively moderate BPH symptoms has been growing steadily. In the present study, acute toxicity of lyophilised aqu...

journal_title：Natural product research

authors： Vitali F,Pennisi G,Attaguile G,Savoca F,Tita B

更新日期：2011-02-01 00:00:00

abstract：:Three biflavonoid glycosides, named carinoside B, C and D (1, 2 and 3, respectively), were isolated from the n-BuOH crude extract of the aerial part of Lomatogonium carinthiacum (Wulfen) Rchb (L. carinthiacum). The structures of 1, 2 and 3 were elucidated by spectroscopic methods, including UV, IR, HR-ESI-MS and exten...

journal_title：Natural product research

authors： Bao B,Wang Q,Wu X,Tai W

更新日期：2015-01-01 00:00:00

abstract：:As part of continuing our research on diverse C-7 derivatives of camptothecin (CPT), 16 CPT derivatives bearing piperazinyl-thiourea chemical scaffold and different substituent groups have been designed, synthesized and evaluated in vitro for cytotoxicity against five tumor cell lines (A-549, MDA-MB-231, MCF-7, KB and...

journal_title：Natural product research

authors： Song ZL,Yang GZ,Li JC,Liu YQ,Yang CJ,Goto M,Zhang ZJ,Morris-Natschke SL,Liu H,Lee KH

更新日期：2020-07-01 00:00:00

abstract：:A new dolabellane diterpenoid (1R*,3E,7E,9S*,11S*,12Z)-9-hydroxydolabella-3,7,12-triene (1), along with seven known compounds (2-8), has been isolated from the Hainan soft coral Spongodes sp. Their structures were elucidated on the basis of spectroscopic analysis and compared with those previously reported in literatu...

journal_title：Natural product research

authors： Yan XH,Jia R,Shen X,Guo YW

更新日期：2007-08-01 00:00:00

abstract：:A new germacrenolide (1) and fourteen known terpenoids (2-15) were isolated from the barks of Magnolia maudiae (Dunn) Figlar (Magnoliaceae). The structure of (7αH,11βH)-2α,8α-dihydroxy-4α,5β-epoxy-germacr-1(10)-en-6α,12-olide (1) was elucidated by physical and spectroscopic data analysis, including 1D, 2D NMR and HR-E...

journal_title：Natural product research

authors： Xianjin S,Sha S,Qi M,Zhang Z,Yang Y,Wu H,Li L,Wang W,Huang A

更新日期：2018-07-01 00:00:00

abstract：:Two novel secondary metabolites, including one thujopsene-type sesquiterpene designated thujasutchin N (1) and one norlignan named thujasutchin O (2) were obtained from the ethanolic extract of the stems and roots of Thuja sutchuenensis. Among them, thujasutchin O (2) represents the first example of lignan sharing a u...

journal_title：Natural product research

authors： Wang M,Huo L,Liu H,Zhao L,Xu Z,Tan H,Qiu SX

更新日期：2020-10-23 00:00:00

abstract：:The comet assay-guided fractionation of the twigs of Manglietia hookeri resulted in the isolation of three sesquiterpene-neolignans, including a new one 5-allyl-2-(4-allyl-phenoxy)-3-[7-(1-hydroxy-1-methyl-ethyl)-1, 4a-dimethyl-decahydro-naphthalen-1-yloxy]-phenol (1), and eudesobovatol A (2) and eudesobovatol B (3), ...

journal_title：Natural product research

authors： Hu X,Sui X,Wang Y,Wang W,Wu H,Zhang F,Tan Y,Zhang F

更新日期：2016-07-01 00:00:00

abstract：:One new xanthone, chryxanthone C (1), together with four known analogues (2-5), were isolated from the cultures of Paecilamyces sp. TE-540, an endophytic fungus obtained from the leaves of Nicotiana tabacum L. The structure of 1 was elucidated by comprehensive spectral analysis including HRESIMS and 1D/2D NMR, which w...

journal_title：Natural product research

authors： Li XQ,Dong QJ,Xu K,Yuan XL,Liu XM,Zhang P

更新日期：2020-10-04 00:00:00

abstract：:Stichopus hermanni and Stichopus vastus are sea cucumber species from the Stichopodidae family within the coastal waters of Malaysia. The integument of these invertebrates is hypothesised to contain abundant glycosaminoglycans (GAGs). GAGs are divided into non-sulphated and sulphated GAGs. Sulphated GAGs have various ...

journal_title：Natural product research

authors： Masre SF,Yip GW,Sirajudeen KN,Ghazali FC

更新日期：2012-01-01 00:00:00

abstract：:Illicium lanceolatum is a popular aromatic and medicinal plant in China. Essential oil from the roots of I. lanceolatum, obtained by hydrodistillation, was analysed by GC-MS. The essential oil was dominated by phenylpropenes. The major components were myristicin (17.63%), α-asarone (17.23%), methyl isoeugenol (11.19%)...

journal_title：Natural product research

authors： Liang J,Huang B,Wang G

更新日期：2012-01-01 00:00:00

abstract：:Physalins are seco-steroids with a variety of pharmacological activities already described. In this study the pharmacological properties of a standardized concentrated ethanolic extract from Physalis angulata (CEEPA), rich in physalins B, D, F and G, were studied in models of pain and inflammation in mice. Inflammator...

journal_title：Natural product research

authors： do Espírito Santo RF,Lima MDS,Juiz PJL,Opretzka LCF,Nogueira RC,Ribeiro IM,Tomassini TCB,Soares MBP,Villarreal CF

更新日期：2019-12-24 00:00:00

abstract：:Accumulating evidences have shown the beneficial effects of natural products for Alzheimer's disease (AD) treatment. The present study was designed to investigate the neuroprotective effects of secondary metabolites of Galactomyces geotrichum (SMGG) on D-galactose induced AD mice. SMGG was extracted and its toxicologi...

journal_title：Natural product research

authors： Wang F,Wang F,Chen T

更新日期：2020-04-15 00:00:00

abstract：:Three flavonoid compounds were isolated from the roots of medicinal plant Tadehagi triquetrum (L.) H.Ohashi, also known as Desmodium triquetrum (Fabaceae). On the basis of the chemical and spectral analysis, the compounds were identified as baicalein (Flavone), naringin and neohesperidin (Flavonone). To the best of ou...

journal_title：Natural product research

authors： Vedpal,Jayaram U,Wadhwani A,Dhanabal SP

更新日期：2020-07-01 00:00:00

abstract：:Two new norsesquiterpenes were isolated from the extracts of the roots and rhizomes of Ligularia lapathifolia (Franch.) Hand.-Mazz. Their structures were identified as 2-acetyl-3a-methyl-5-(2-methyl-but-2-enoyloxy)-3a,4,5,6,7,7a-hexahydro-H-indene-4-carboxylic acid (1) and 2-acetyl-8a-methyl-2-(2-methyl-but-2-enoyloxy...

journal_title：Natural product research

authors： Li YS,Wang ZT,Zhang M,Chen JJ,Luo SD

更新日期：2004-04-01 00:00:00

abstract：:The hexane fraction from the roots of Echinops ellenbeckii O. Hoffm. from Ethiopia yielded seven acetylenic thiophenes of which five compounds (1, 3, 4, 6, 7) are reported for the first time in this species: the monothiophenes 5-(penta-1,3-diynyl)-2-(but-3-en-1-ynyl)-thiophene (1), 5-(penta-1,3-diynyl)-2-(4-acetoxy-bu...

journal_title：Natural product research

authors： Hymete A,Rohloff J,Kjøsen H,Iversen TH

更新日期：2005-12-01 00:00:00

abstract：:A new polyoxygenated briarane-type diterpenoid, briarenol A (1), has been isolated from a gorgonian coral belonging to the genus Briareum. The structure, including the relative stereochemistry of briarane 1, was elucidated by the interpretation of spectral data. The configuration of 1 was further supported by molecula...

journal_title：Natural product research

authors： Sung PJ,Hu WP,Fang LS,Fan TY,Wang JJ

更新日期：2005-10-01 00:00:00

abstract：:Artemisia annua L. is an annual Eurasian desert-steppe plant. The composition of essential oils found in Artemisia annua from Russian (Buryatian) flora was analyzed in this work using gas chromatography mass-spectrometry method. Artemisia ketone, β-selinene, caryophyllene, caryophyllene oxide, germacrene D were the ma...

journal_title：Natural product research

authors： Zhigzhitzhapova SV,Dylenova EP,Gulyaev SM,Randalova TE,Taraskin VV,Tykheev ZA,Radnaeva LD

更新日期：2020-09-01 00:00:00

abstract：:Azadirachtin-A (Aza-A, figure 1) was subjected to a variety of synthetic transformations and the antifeedant activity and toxicity of the azadirachtin derivatives were assessed against second instar larvae Spodoptera litura on castor leaves in comparison with the crude material containing 9.14% Aza-A, as well as relat...

journal_title：Natural product research

authors： Deota PT,Upadhyay PR

更新日期：2005-07-01 00:00:00

abstract：:One new indole alkaloid (1) and one new indole alkaloidal glycoside (2), together with nine known alkaloids (3-11), were isolated from the leaves of Evodia rutaecarpa. Their structures were determined on the basis of spectroscopic and chemical methods. Compound 4 exhibited potent activity against Pseudomonas aeruginos...

journal_title：Natural product research

authors： Xia X,Luo JG,Liu RH,Yang MH,Kong LY

更新日期：2016-10-01 00:00:00

abstract：:Continued investigation of the marine alga Laurencia claviformis has led to the isolation of pacifenol, a halogenated sesquiterpene as the major metabolite. The microbial transformation of pacifenol is reported. It was cultivated with a marine strain of Penicillium brevicompactum yielding a new compound. The structure...

journal_title：Natural product research

authors： San-Martín A,Rovirosa J,Astudillo L,Sepúlveda B,Ruiz D,San-Martín C

更新日期：2008-12-01 00:00:00