Chemical composition, antinociceptive and anti-inflammatory properties of essential oil from the roots of Illicium lanceolatum.

Abstract:

:Illicium lanceolatum is a popular aromatic and medicinal plant in China. Essential oil from the roots of I. lanceolatum, obtained by hydrodistillation, was analysed by GC-MS. The essential oil was dominated by phenylpropenes. The major components were myristicin (17.63%), α-asarone (17.23%), methyl isoeugenol (11.19%), apiol (8.82%) and isolongifolol (5.94%). When investigated using acetic acid-induced abdominal writhe models and the xylene-induced ear oedema model, the essential oil showed significantly antinociceptive and anti-inflammatory effects. The results indicate that the essential oil may contain the bioactive components of I. lanceolatum. This is the first report on the chemistry, antinociceptive and anti-inflammatory activities of I. lanceolatum.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Liang J,Huang B,Wang G

doi

10.1080/14786419.2011.603318

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

1712-4

issue

18

eissn

1478-6419

issn

1478-6427

journal_volume

26

pub_type

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