Xanthones from roots of Calophyllum thwaitesii and their bioactivity.

abstract：:The current study introduces a new idea of utilising several bio/chemoinformatics tools in comparing two bio-similar natural molecules viz. curcumin and bisdemethoxycurcumin (BDMC) in order to select a potential nose-to-brain remedy for Alzheimer disease. The comparison comprised several bio/chemo informatics tools. I...

journal_title：Natural product research

authors： Hathout RM,El-Ahmady SH,Metwally AA

更新日期：2018-12-01 00:00:00

abstract：:Comparison of an authentic sample of altertenuol with altenuisol obtained by total synthesis and analysis of nuclear magnetic resonance spectra unambiguously revealed that altertenuol and altenuisol are identical compounds. ...

journal_title：Natural product research

authors： Thomas R,Nemecek G,Podlech J

更新日期：2013-01-01 00:00:00

abstract：:The ethanolic extract of the stems of Viburnum fordiae Hance showed insecticidal and α-glucosidase inhibitory activities and then was fractionated by bioactivity-guided fractionation to obtain a rare C13-norisoprenoid (1), together with a new phenolic glycoside (2), and seven known compounds, alangionoside C (3), pisu...

journal_title：Natural product research

authors： Shao JH,Chen J,Zhao CC,Shen J,Liu WY,Gu WY,Li KH

更新日期：2019-09-01 00:00:00

abstract：:Six new compounds, including three terpenoids (1-3) and three lignans (4-6), were isolated from the 95% EtOH extract of the twigs of Tripterygium hypoglaucum. Their structures were determined on the basis of extensive spectroscopic analysis. 9'-O-benzoyl-lariciresinol (4) showed weak cytotoxicity against HepG2/Adr cel...

journal_title：Natural product research

authors： Zheng H,Wang L,Yang T,Liu D,Li HM,Chen XQ,Li RT

更新日期：2020-07-01 00:00:00

abstract：:The search for bioactive compounds against diseases is imperative and the richness of the Amazon provides a large source to be explored. Current therapies for the treatment of parasitic infections have severe side effects and low efficacy, which makes the development of an effective chemotherapy extremely important. I...

journal_title：Natural product research

authors： Fernandes NS,Desoti VC,Dias A,da Silva YC,de Azevedo Dos Santos AP,Passarini GM,Nakamura CV,da Veiga Junior VF

更新日期：2020-01-25 00:00:00

abstract：:The aim of study was to compare the content of phenolic acids and flavonoids in two cultivars of Lavandula angustifolia: 'Blue River' and 'Ellagance Purple', including flowers and leafy stalks. Total phenolics and total flavonoids contents were determined by UV-Vis spectroscopy. The contents of total phenolics in leaf...

journal_title：Natural product research

authors： Adaszyńska-Skwirzyńska M,Dzięcioł M

更新日期：2017-11-01 00:00:00

abstract：:Two new glycerol esters, (S)-2-hydroxy-3-(octanoyloxy)propyl tetracosanoate (1) and (S)-3-(((S)-11-acetoxy octadecanoyl)oxy)propane-1,2-diyl diacetate (2), and eight known compounds, docosanedioic acid (3), 2,5-dimethylnonadecane (4), lupeol (5), stigmasterol (6), β-sitosterol (7), heptadecanoic acid (8), hexanedioic ...

journal_title：Natural product research

authors： Forestrania RC,Anaya-Eugenio GD,Acuña UM,Ren Y,Elya B,de Blanco EC

更新日期：2020-06-12 00:00:00

abstract：:Three new sesquiterpenes: 4-acrylic-6-methyl-α-tetralone (1), ainsliaea acid A (2) and ainsliaea acid B (3), together with 8 known compounds (4-11) were isolated from the whole herb of Ainsliaea glabra and their structures were established by means of 1D and 2D NMR spectroscopy and HR-ESIMS. Compounds 1-6 were tested ...

journal_title：Natural product research

authors： Chen YP,Tong C,Lu WQ,Shen YH,Wu ZJ,Chen WS

更新日期：2019-01-01 00:00:00

abstract：:Chemical investigation of the stems of Epigunum griffithianum led to the isolation and identification of a new triterpenoid saponin (1) and two known compounds (epigynosides A (2) and B (3)). These structures were elucidated by means of spectroscopic analysis (1D and 2D NMR, MS, UV, IR) as well as comparison with the ...

journal_title：Natural product research

authors： Wang Q,Li WY,Wang YD

更新日期：2020-05-01 00:00:00

abstract：:A new C20-diterpenoid alkaloid carmichaedine (1) and six known alkaloids (2-7) were isolated from the lateral roots of Aconitum carmichaeli. Their structures were established on the basis of extensive spectroscopic analyses. Compound 1 exhibited potent antibacterial activity against Bacillus subtilis with minimum inhi...

journal_title：Natural product research

authors： Yu J,Yin TP,Wang JP,Mei RF,Cai L,Ding ZT

更新日期：2017-01-01 00:00:00

abstract：:A series of 4-hydroxy-3,4-dialkyl-2,6-diaryl-piperidine (7-12) have been synthesised by reduction of 3-alkyl-2,6-diarylpiperidin-4-one using the Grignard reagent. Structural assignments and conformational analysis of the compounds were established based on the spectral studies. All the piperdin-4-ol derivatives (7-12)...

journal_title：Natural product research

authors： Maruthavanan T,Venkatesan P

更新日期：2013-01-01 00:00:00

abstract：:A new triterpene saponin (1) was isolated from a methanol extract of Swartzia apetala Raddi var. glabra, together with the flavonoids mauritianin (2), kaempferol (3) and the triterpene saponin β-D-glucopyranosyl 3β-hydroxy-olean-12-en-28-oate (4). These compounds were characterised on the basis of their spectral data,...

journal_title：Natural product research

authors： de Araújo MF,Curcino Vieira IJ,Sant'Anna CM,da Silva DR,Vitorino Maia AI,Braz-Filho R,Vieira-da-Motta O,Mathias L

更新日期：2013-10-01 00:00:00

abstract：:In this study the crude ethyl acetate extracts and fractions from red algae Gracilaria edulis were studied against fish pathogens. G. edulis was extracted with ethyl acetate, fractionated in silica gel coloum chromatography and gradient hexane-ethyl acetate. The extract and fractions were subjected for bioassay guided...

journal_title：Natural product research

authors： Kasanah N,Amelia W,Mukminin A,Triyanto,Isnansetyo A

更新日期：2019-11-01 00:00:00

abstract：:Two new chromones, spororrminone A (1, (S)-5-hydroxy-2-methyl-4-oxo-2-((S)-5-oxotetrahydrofuran-2-yl)chroman-7-carboxylic acid) and 2-epi-spororrminone A (2, (R)-5-hydroxy-2-methyl-4-oxo-2-((S)-5-oxotetrahydrofuran-2-yl)chroman-7-carboxylic acid), were isolated from an EtOAc extract of an endolichenic fungal strain Sp...

journal_title：Natural product research

authors： Huang MJ,Li YJ,Tang J,Chen GD,Hu D,Xu W,Guo LD,Yao XS,Gao H

更新日期：2020-11-01 00:00:00

abstract：:A new cinnamolyglycoflavonoid 3-cinnamoyltribuloside (1), its precursor tribuloside and two known flavonoid glycosides afzelin and astilbin were isolated from Heritiera littoralis Dryand (Sterculiaceae) ethanolic leaf extract. The dichloromethane leaf extract afforded two known pentacyclic triterpenoids, 3β-taraxerol ...

journal_title：Natural product research

authors： Christopher R,Nyandoro SS,Chacha M,de Koning CB

更新日期：2014-01-01 00:00:00

abstract：:Phytochemical investigation of chloroform extract from the leaves of the marine plant Posidonia oceanica (L.) Delile (Posidoniaceae), yielded posidozinol, a new methylated sesquiterpene along with β-sitosterol and four known fatty acids: palmitic, palmitoleic, oleic and linoleic acids. The structure elucidation has be...

journal_title：Natural product research

authors： Hammami S,Salem AB,Ashour ML,Cheriaa J,Graziano G,Mighri Z

更新日期：2013-01-01 00:00:00

abstract：:Phenolics were extracted from powdered pomegranate peel using water, methanol, acetone and ethyl acetate (EtOAc), respectively. The antiliperoxidant activity of the extracts on lard was studied by peroxide value method. All the extracts showed enhanced inhibitory effect on lard peroxidation with the increase of phenol...

journal_title：Natural product research

authors： Zhang Q,Jia D,Yao K

更新日期：2007-03-01 00:00:00

abstract：:Investigation on the leaves of Melicope bonwickii (F.Muell.) T.Hartley (Rutaceae) afforded a new 7-(2'-hydroxy-3'-chloroprenyloxy)-4-methoxyfuroquinoline (1) together with the known 7-(2',3'-epoxyprenyloxy)-4-methoxyfuroquinoline (2), evellerine (3) kokusaginine (4) and an amide aurantiamide acetate (5). Compounds 1 a...

journal_title：Natural product research

authors： Komala I,Rahmani M,Sukari MA,Mohd Ismail HB,Cheng Lian GE,Rahmat A

更新日期：2006-04-01 00:00:00

abstract：:Momordica charantia (family, Cucurbitaceae), commonly known as karela or bitter melon (Japanese name 'Tsurureishi'), is used as a folk medicine in China, the Indian subcontinent and South America. In Chinese traditional medicine, the plant is usually used as a hypoglycaemic and anti-diabetic agent. The hypoglycaemic a...

journal_title：Natural product research

authors： Han C,Hui Q,Wang Y

更新日期：2008-01-01 00:00:00

abstract：:In this study, the ethanol extract of Momordica dioica fruit extract (200 mg kg(-1)) was studied for nephroprotective and curative activities. Chloroform, ethyl acetate, ethanol and aqueous extracts were prepared. In vitro antioxidant activity was made the basis for the selection of the ethanol extract for further stu...

journal_title：Natural product research

authors： Jain A,Singhai AK

更新日期：2010-05-01 00:00:00

abstract：:Alternanthera brasiliana is popularly known as 'penicillin' and used as an anti-inflammatory and for wound healing. The objective of this work was the phytochemical study of the species by analytical techniques such as LC-MS/MS and GC-MS. Twenty-seven compounds were identified, five by LC-MS and 22 by GC-MS analysis. ...

journal_title：Natural product research

authors： Alencar Filho JMT,Teixeira HAP,Sampaio PA,Pereira ECV,Amariz IAE,Rolim Neto PJ,Rolim LA,Araújo ECDC

更新日期：2020-02-01 00:00:00

abstract：:To obtain more accessible oxidative stress inhibitors, a series of novel spin-labelled derivatives of 3-hydroxybutanolide (2a-d, 3a-d) with the natural active compound (kinsenoside) as the lead compound were designed, synthesised from the nitroxide free radical piperidine (pyrroline) and the main structural unit of ki...

journal_title：Natural product research

authors： Liu Q,Liu ZL,Tian J,Shi W,Liu YQ

更新日期：2014-01-01 00:00:00

abstract：:The aim of this study was to explore the extract/fractions and compounds of Diospyros lotus against various Gram-positive and Gram-negative bacteria strain. The results showed marked susceptibility of extract and its fractions against test pathogens. Among them, chloroform fraction was most dominant and effective agai...

journal_title：Natural product research

authors： Rauf A,Uddin G,Khan H,Arfan M,Siddiqui BS

更新日期：2016-01-01 00:00:00

abstract：:Sasa coreana Nakai (SCN) is a medicinal plant commonly used against inflammation. However, the underlined mechanisms against skin inflammation is poorly understood. The present study investigated the effects of SCN leave extract on ear inflammation. To this aim, six-week-old male ICR mice was subjected to 12-O-tetrade...

journal_title：Natural product research

authors： Khan I,Dey DK,Lee JH,Kang SC

更新日期：2020-04-14 00:00:00

abstract：:An alternative method for the synthesis of the 8-methyl-1-tetralone from the commercially available 5-methoxy-1-tetralone has been developed. The transformation involves eight steps and affords an overall yield 25%. ...

journal_title：Natural product research

authors： Poon PS,Bedoya L,Churio GJ,Banerjee AK

更新日期：2014-01-01 00:00:00

abstract：:This study is designed to examine the chemical composition of the essential oil obtained from Buddleja thyrsoides Lam leaves from south Brazil. Gas chromatography/mass spectrometry analysis resulted in the detection of 12 components, representing 91.4% of the total oil composition. Germacrene D (27.16%), 1,10-di-epi-C...

journal_title：Natural product research

authors： Mahlke JD,Boligon AA,Machado MM,Athayde ML

更新日期：2013-01-01 00:00:00

abstract：:First total synthesis of carpatamide-A 7a, cytotoxic arylamine derivative isolated from marine derived Streptomyces sp., was achieved in twelve steps with overall yield of 24% with seven longest linear steps. In the penultimate step, dienoic acid 13 and an amino-phenylpropionic acid methyl ester core 21 were coupled t...

journal_title：Natural product research

authors： Burman RP,Gupta S,Bhatti J,Verma K,Rajak D,Gill MS

更新日期：2019-04-01 00:00:00

abstract：:A megastigmane sulphoglycoside together with three phenolic compounds were isolated from the water-soluble fraction of the pericarps of Garcinia mangostana. The structure of the new compound was determined as 4-O-sulpho-β-d-glucopyranosyl abscisate (1) by spectroscopic data. Proanthocyanidin A2 (2) showed potent α-glu...

journal_title：Natural product research

authors： Tran TH,Le Huyen T,Tran TM,Nguyen TA,Pham TB,Nguyen Tien D

更新日期：2016-07-01 00:00:00

abstract：:A new flavonol glycoside named Sabiapside A (1), along with four known compounds, quercetin-3-O-gentiobioside (2), camellianoside (3), isobariclisin-3-O- rutinoside (4), tsubakioside A (5), was isolated from Sabia parviflora. Their structures were elucidated by extensive spectroscopic analysis including MS, UV, IR and...

journal_title：Natural product research

authors： Sun Q,Pan G,Xu W,Lu X,Bai C,Liu M,Chen Y

更新日期：2019-10-29 00:00:00

abstract：:The aerial portions of Cynara scolymus commonly have been eaten as vegetables or functional foods by the people lived in Mediterranean region. In preliminary antioxidant screening, the rhizome portions (CSR) of this species showed better potential than leaves ones. However, neither phytochemical nor pharmacology studi...

journal_title：Natural product research

authors： Lee CL,Liao KC,Chen CC,Lin YA,Wu TY,Jhan YL,Chen CJ,Yang JC,Wu YC

更新日期：2019-07-30 00:00:00