A new cinnamoylglycoflavonoid, antimycobacterial and antioxidant constituents from Heritiera littoralis leaf extracts.

Abstract:

:A new cinnamolyglycoflavonoid 3-cinnamoyltribuloside (1), its precursor tribuloside and two known flavonoid glycosides afzelin and astilbin were isolated from Heritiera littoralis Dryand (Sterculiaceae) ethanolic leaf extract. The dichloromethane leaf extract afforded two known pentacyclic triterpenoids, 3β-taraxerol and friedelin. Extracts and compounds isolated therefrom, with the exception of 3β-taraxerol, exhibited antimycobacterial activity against the non-pathogenic Mycobacterium species Mycobacterium madagascariense and Mycobacterium indicus pranii, with a minimum inhibitory concentration (MIC) 5.0 mg/mL for the crude extracts and MICs in the range of 1.6-0.8 mg/mL for the pure compounds. The extracts together with 3-cinnamoyltribuloside (1), tribuloside and astilbin exhibited 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity. The compounds that showed dual activities could be further evaluated under clinical settings for co-administration with standard anti-tuberculosis drugs.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Christopher R,Nyandoro SS,Chacha M,de Koning CB

doi

10.1080/14786419.2013.863202

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

351-8

issue

6

eissn

1478-6419

issn

1478-6427

journal_volume

28

pub_type

杂志文章
  • Isolation of chemical constituents from Enicosanthum cupulare (King) Airy-Shaw.

    abstract::Six chemical constituents were isolated from Enicosanthum cupulare (King) Airy-Shaw. The structures of the isolated compounds were determined using 1D, 2D-NMR and were found to be identical to those previously reported for these compounds. Three aporphine alkaloids, O-methylmoschatoline, liriodenine and oxostephanine ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786411003774338

    authors: Fujita S,Ninomiya M,Efdi M,Ohguchi K,Nozawa Y,Koketsu M

    更新日期:2010-10-01 00:00:00

  • A novel antiplasmodial 3',5'-diformylchalcone and other constituents of Friesodielsia obovata.

    abstract::Phytochemical investigation of the stem and root barks of Friesodielsia obovata Benth (Annonaceae) afforded new 3',5'-diformyl-2',4',6'-trihydroxychalcone and N-formyl-7-hydroxyglaucine together with five known compounds, 3',5'-dimethyl-2',4',6'-trihydroxychalcone, (-)-crotepoxide, demethoxymatteucinol, lawinal, and b...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410701194310

    authors: Joseph CC,Magadula JJ,Nkunya MH

    更新日期:2007-09-01 00:00:00

  • A novel alkaloid from the seeds of Sophora alopecuroides L.

    abstract::A new cytisine-type alkaloid, along with five known alkaloids was obtained from the seeds of Sophora alopecuroides. Their structures were determined to be (-)-N-(2'-hydroxy-3',5'-di-tert-butyl-toluene)-cytisine (1), (-)-lupanine (2), (+)-matrine (3), (+)-sophoramine (4), (+)-lehmannine (5) and (-)-sophocarpine (6). Th...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1824226

    authors: Rong ZJ,Gao XX,Hu GS,Yan T,Jia JM,Wang AH

    更新日期:2020-09-23 00:00:00

  • Comparative larvicidal activity of different species of Ocimum against Culex quinquefasciatus.

    abstract::Ocimum is a genus of aromatic herbs, undershurbs or shrubs distributed in the tropical and warm temperate regions of the world. Larvicidal activity of essential oils and different extracts of O. sanctum, O. basilicum and O. gratissimum were compared on laboratory reared and field collected larvae of Culex quinquefasci...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2010.551755

    authors: Rajamma AJ,Dubey S,Sateesha SB,Tiwari SN,Ghosh SK

    更新日期:2011-12-01 00:00:00

  • Chemical characterization and bioactivity of the essential oil from Santolina insularis, a Sardinian endemism.

    abstract::Santolina insularis is a Sardinian endemism that is widely used in traditional medicine. The essential oil was obtained with a yield of 2.7% and is mainly characterized by β-phellandrene (22.6%), myrcene (11.4%) and artemisia ketone (7.6%). The oil significantly reduced NO production without affecting macrophages viab...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1774764

    authors: Alves-Silva JM,Piras A,Porcedda S,Falconieri D,Maxia A,Gonçalves MJ,Cruz MT,Salgueiro L

    更新日期:2020-06-04 00:00:00

  • Essential oil composition of Rydingia michauxii (Briq.) Scheen & V.A. Albert endemic of Iran.

    abstract::The chemical composition of the essential oil (EO) obtained from the aerial parts of Rydingia michauxii (Briq.) Scheen & V.A. Albert was analysed by gas chromatography and gas chromatography/mass spectrometry (GC/MS). Eighty components were identified in the oil with caryophyllene oxide (20.1%), trans-verbenol (10.2%)...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1343321

    authors: Karami A,Esmaeili H,Shahbazian D

    更新日期:2018-01-01 00:00:00

  • Microwave assisted henna organic dyeing of polyester fabric: a green, economical and energy proficient substitute.

    abstract::The proposed work, aims to provide a "green" and cutting-edge technique for the mordanting and dyeing of polyester fabric with natural henna dye using the advanced technology of micro waves. For providing a complete "green" and ecofriendly dyeing process, lemon was used as a natural bio mordant with micro waves and re...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1619721

    authors: Arain RA,Ahmad F,Khatri Z,Peerzada MH

    更新日期:2021-01-01 00:00:00

  • Bioactive mushroom polysaccharides as antitumor: an overview.

    abstract::Immuno-therapies are gaining more importance to treat certain forms of cancer. The goal of therapies is to enhance person's own IgG, IgA, IgM, IgD, IgE and macrophages to combat with neoplastic cells hence the effectiveness of the immune system. Since, early civilization mushrooms are considered as potent food as well...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1466129

    authors: Pandya U,Dhuldhaj U,Sahay NS

    更新日期:2019-09-01 00:00:00

  • Anti-infective potential of caffeic acid and epicatechin 3-gallate isolated from methanol extract of Euphorbia hirta (L.) against Pseudomonas aeruginosa.

    abstract::Euphorbia hirta (L.) plant is traditionally used in Malaysia for the treatment of gastrointestinal, bronchial and respiratory ailments caused by nosocomial infectious agents. Bioactivity-guided fractionation of the methanol extract of the aerial parts of E. hirta and analysis using high-performance liquid chromatograp...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.999242

    authors: Perumal S,Mahmud R,Ramanathan S

    更新日期:2015-01-01 00:00:00

  • A new monoterpenoid indole alkaloid from Ochrosia elliptica.

    abstract::A new monoterpenoid indole alkaloid, 10-methoxyakuammidine (1), together with four known alkaloids (2-5), were isolated from the stems and leaves of Ochrosia elliptica. The structure of 1 was elucidated by extensive spectroscopic methods and the known compounds were identified by comparisons with data reported in the ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2016.1277349

    authors: Chen AH,Liu QL,Ma YL,Jiang ZH,Tang JY,Liu YP,Chen GY,Fu YH,Xu W

    更新日期:2017-07-01 00:00:00

  • Two nematicidal furocoumarins from Ficus carica L. leaves and their physiological effects on pine wood nematode (Bursaphelenchus xylophilus).

    abstract::The ethanol extract of the Ficus carica L. leaves was tested to show strong nematicidal activity against pine wood nematode (PWN), Bursaphelenchus xylophilus, causing 90.93% corrected mortality within 72 h at 1.0 mg/mL. From the ethyl acetate soluble fraction of the F. carica L. leaves extract, the main nematicidal co...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2015.1094804

    authors: Guo Q,Du G,He H,Xu H,Guo D,Li R

    更新日期:2016-09-01 00:00:00

  • Alkaloids from the fungus Lactarius subplinthogalus.

    abstract::A new alkaloid, namely laccarin A (1), along with four known alkaloids, laccarin (2), adenosine (3), indole-3-carboxaldehyde (4) and nicotinamide (5), was isolated from the fungus Lactarius subplinthogalus. The structure of laccarin A (1) was established mainly by spectroscopic methods. ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410310001608073

    authors: Wang Y,Yang SP,Wu Y,Yue JM

    更新日期:2004-04-01 00:00:00

  • Two novel coumarins bearing an acetophenone derivative from the leaves of Melicope Quercifolia.

    abstract::Meliquercifolins A (1), and B (2), two new coumarins are bearing an acetophenone derivative were isolated from the leaves of Melicope quercifolia along with three known compounds, melicodenines E (3), F (4) and I (5). Structures of two new compounds were identified based on spectroscopic analyses (UV, HR-ESI-MS, 1 D a...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1644634

    authors: Saputri RD,Tjahjandarie TS,Tanjung M

    更新日期:2019-07-22 00:00:00

  • Isolation of a larvicidal compound from Piper solmsianum C.DC. (Piperaceae).

    abstract::The Aedes aegypti mosquito is one of the major vectors of arboviruses. These diseases have re-emerged and the insecticides used nowadays are toxic to mammals and environment and have only been effective in the short-term. In this context, natural products are an alternative. The genus Piper has many active compounds a...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1374265

    authors: Macedo AL,Duprat RC,Moreira DL,Kaplan MAC,Vasconcelos TRA,Pinto LC,Montenegro RC,Ratcliffe NA,Mello CB,Valverde AL

    更新日期:2018-11-01 00:00:00

  • A new steroidal glycoside from the fruits of Solanum myriacanthum.

    abstract::A new cholestane-type steroidal glycoside, solamyriaside A (1), was isolated from the fruits of Solanum myriacanthum Dunal (Solanaceae), along with two known steroidal glycosides, namely, solaviaside A (2) and aculeatiside A (3), and three known steroidal alkaloid glycosides, namely, solamargine (4), khasianine (5) an...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1781117

    authors: Ono M,Shimode M,Tsutsumi S,Yasuda S,Okawa M,Kinjo J,Miyashita H,Ikeda T,Yoshimitsu H,Nohara T

    更新日期:2020-06-19 00:00:00

  • Development, characterisation, stability study and antileukemic evaluation of nanoemulsions containing Astrocaryum aculeatum extract.

    abstract::The objective of this work was to produce and characterise nanoemulsions containing tucumã extract and to evaluate the performance of the nanostructure and the free compound regarding antitumor activity, cytotoxicity, and oxidative metabolism in NB4/APL cells. The nanoemulsions showed adequate physicochemical characte...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1862830

    authors: Copetti PM,Gündel SDS,de Oliveira PSB,Favarin FR,Ramos AP,Pintos FG,Pappis L,Gündel A,Machado AK,Ourique AF,Sagrillo MR

    更新日期:2020-12-24 00:00:00

  • Survey of 2,11-cyclized cembranoids from Caribbean sources.

    abstract::This review covers the literature published since the report of the first compound to December 2006, for marine natural 2,11-cyclized cembranoids isolated from Caribbean sources, with 30 citations, most of them from 2000 to 2006, referring to compounds isolated from the Caribbean gorgonian octocorals Briareum asbestin...

    journal_title:Natural product research

    pub_type: 杂志文章,评审

    doi:10.1080/14786410701760797

    authors: Cóbar OM

    更新日期:2009-01-01 00:00:00

  • Insecticidal activity of the essential oil of Perovskia artemisioides Boiss.

    abstract::This work reports the phytochemical profile and insecticidal properties of Perovskia artemisioides Boiss essential oil (PAEO) collected in Baluchestan, Iran. Totally, twenty-six substances were identified with 1,8-cineole (25.81%), geranyl acetate (13.00%) and linalool (10.21%) as dominant chemical metabolites by GC-M...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1803311

    authors: Sadeghi Z,Alizadeh Z,Khorrami F,Norouzi S,Moridi Farimani M

    更新日期:2020-08-26 00:00:00

  • SPME-GC-MS analysis of commercial henna samples (Lawsonia inermis L.).

    abstract::The aim of this work was to provide a characterisation of volatile constituents from different commercial batches of henna (Lawsonia inermis) leaves of different geographic origin. Headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC-MS) was used for the purpose. A tota...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2015.1055491

    authors: Mengoni T,Peregrina DV,Censi R,Cortese M,Ricciutelli M,Maggi F,Di Martino P

    更新日期:2016-01-01 00:00:00

  • UHPLC-MS/MS phenolic profiling and in vitro antioxidant activities of Inula graveolens (L.) Desf.

    abstract::Inula graveolens (L.) Desf. is an annual aromatic herb which has various uses on alternative medicine in many region of the world. In this study, antioxidant activities of ethanol and water extracts of the plant leaves were determined by in vitro DPPH method and phenolic composition of the plant sample was determined ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1350673

    authors: Silinsin M,Bursal E

    更新日期:2018-06-01 00:00:00

  • Pictalignans D-F, three new neolignan derivatives from Selaginella picta.

    abstract::Three new neolignan derivatives (1-3), together with three known isolariciresinol derivatives (4-6) were isolated from Selaginella picta. Their structures were elucidated by spectroscopic methods (1D/2D NMR, HRESIMS and CD). All isolated compounds were assayed on the neuroprotective activity against the injury of HT-2...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1560284

    authors: Cheng F,Zou ZX,Xu PS,Zhang SH,Zhang Y,Yao CP,Xu KP,Tan GS

    更新日期:2020-05-01 00:00:00

  • Pharmaceutical potential of phorbol esters from Jatropha curcas oil.

    abstract::Phorbol esters (PEs) are diterpenes present in Jatropha curcas L. seeds and have a myriad of biological activities. Since PEs are toxic, they are considered to be futile in Jatropha-based biodiesel production chain. In the present study, the extracted PEs from Jatropha oil were used as a starting material to synthesis...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2012.716057

    authors: Devappa RK,Malakar CC,Makkar HP,Becker K

    更新日期:2013-01-01 00:00:00

  • Biologically active metabolites from fungi, 19: new isocoumarins and highly substituted benzoic acids from the endophytic fungus, Scytalidium sp.

    abstract::Six known metabolites, two new isocoumarins 4 and 8, and one new highly substituted benzoic acid derivative 9 were isolated from the ethyl acetate culture extract of a fungal endophyte, Scytalidium sp. In addition, another new benzoic acid 10 with an unusual 1,2-dicarbonyl side chain was indirectly identified from its...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410310001620637

    authors: Krohn K,Sohrab MH,Aust HJ,Draeger S,Schulz B

    更新日期:2004-06-01 00:00:00

  • Antibacterial effects of Brazilian and Bulgarian propolis and synergistic effects with antibiotics acting on the bacterial DNA and folic acid.

    abstract::Propolis is a honeybee product that has been used since ancient times because of its therapeutic effects. It can be used in the development of alternative therapies for the treatment of many diseases, and because propolis shows antibacterial action, this work was carried out in order to investigate a possible synergis...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786411003754355

    authors: Orsi RO,Fernandes A Jr,Bankova V,Sforcin JM

    更新日期:2012-01-01 00:00:00

  • Solid-phase microextraction of volatile organic compounds released from leaves and flowers of Artemisia fragrans, followed by GC and GC/MS analysis.

    abstract::The chemical composition of the volatile organic compounds (VOCs) released from the leaves and flowers of Artemisia fragrans Willd. (Asteraceae) was investigated using headspace solid-phase microextraction (HS-SPME) coupled to gas chromatography (GC) and/or GS/mass spectrometry (GC/MS). The efficiency and reliability ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410903108951

    authors: Movafeghi A,Djozan Dj,Torbati S

    更新日期:2010-08-01 00:00:00

  • A flavanone and antimicrobial activities of the constituents of extracts from Mundulea sericea.

    abstract::In this study, 12 compounds, which include a new flavanone 5-methoxy mundulin, were isolated from the leaves, stem bark and twigs of Mundulea sericea (Willd.) A. Chev. (Fabaceae; Papilionoideae). The structures of the compounds were identified based on spectral data analyses. The constituents of M. sericea also showed...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2011.616504

    authors: Mazimba O,Masesane IB,Majinda RR

    更新日期:2012-01-01 00:00:00

  • New methylated flavonol glucosides from Fumana montana Pomel.

    abstract::Three new methylated flavonol glucosides: 3-methoxy-7-O-β-(6″-galloylgluco-pyranoside) quercetin (1), 3,4'-dimethoxy-7-O-β-(6″-galloyl-glucopyranoside) quercetin (2) and 3-methoxy-7-O-β-(6″-galloylgluco-pyranoside) kaempferol (3), in addition to six known flavonols, were isolated from the ethyl acetate extract of Fuma...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2013.778848

    authors: Laraoui H,Long C,Haba H,Benkhaled M

    更新日期:2013-01-01 00:00:00

  • Chemical composition and antibacterial activity of methanolic extract and essential oil of Iranian Teucrium polium against some of phytobacteria.

    abstract::The antibacterial activity of essential oil and methanolic extract of Teucrium polium was determined against Pseudomonas aeruginosa, Pantoea agglomerans, Brenneria nigrifluens, Rhizobium radiobacter, Rhizobium vitis, Streptomyces scabies, Ralstonia solanacearum, Xanthomonas campestris and Pectobacterium cartovorum by ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.1000320

    authors: Purnavab S,Ketabchi S,Rowshan V

    更新日期:2015-01-01 00:00:00

  • Isopimarane-type diterpenoids from Croton laevigatus.

    abstract::A new isopimarane-type diterpenoid, crolaevinoid A, along with four known analogues was isolated from the twigs and leaves of Croton laevigatus. The structures of the isolated compounds were established on the basis of NMR and MS spectroscopic analyses. The isolated compounds were examined the antibacterial activities...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1596096

    authors: Li MY,Han ZZ,Liu LF,Wu XZ,Huang WJ,Wang K,Yang F,Yuan CS

    更新日期:2020-10-01 00:00:00

  • Antiliperoxidant activity of pomegranate peel extracts on lard.

    abstract::Phenolics were extracted from powdered pomegranate peel using water, methanol, acetone and ethyl acetate (EtOAc), respectively. The antiliperoxidant activity of the extracts on lard was studied by peroxide value method. All the extracts showed enhanced inhibitory effect on lard peroxidation with the increase of phenol...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410601130422

    authors: Zhang Q,Jia D,Yao K

    更新日期:2007-03-01 00:00:00