Abstract:
:A new cinnamolyglycoflavonoid 3-cinnamoyltribuloside (1), its precursor tribuloside and two known flavonoid glycosides afzelin and astilbin were isolated from Heritiera littoralis Dryand (Sterculiaceae) ethanolic leaf extract. The dichloromethane leaf extract afforded two known pentacyclic triterpenoids, 3β-taraxerol and friedelin. Extracts and compounds isolated therefrom, with the exception of 3β-taraxerol, exhibited antimycobacterial activity against the non-pathogenic Mycobacterium species Mycobacterium madagascariense and Mycobacterium indicus pranii, with a minimum inhibitory concentration (MIC) 5.0 mg/mL for the crude extracts and MICs in the range of 1.6-0.8 mg/mL for the pure compounds. The extracts together with 3-cinnamoyltribuloside (1), tribuloside and astilbin exhibited 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity. The compounds that showed dual activities could be further evaluated under clinical settings for co-administration with standard anti-tuberculosis drugs.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Christopher R,Nyandoro SS,Chacha M,de Koning CBdoi
10.1080/14786419.2013.863202subject
Has Abstractpub_date
2014-01-01 00:00:00pages
351-8issue
6eissn
1478-6419issn
1478-6427journal_volume
28pub_type
杂志文章abstract::Six chemical constituents were isolated from Enicosanthum cupulare (King) Airy-Shaw. The structures of the isolated compounds were determined using 1D, 2D-NMR and were found to be identical to those previously reported for these compounds. Three aporphine alkaloids, O-methylmoschatoline, liriodenine and oxostephanine ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786411003774338
更新日期:2010-10-01 00:00:00
abstract::Phytochemical investigation of the stem and root barks of Friesodielsia obovata Benth (Annonaceae) afforded new 3',5'-diformyl-2',4',6'-trihydroxychalcone and N-formyl-7-hydroxyglaucine together with five known compounds, 3',5'-dimethyl-2',4',6'-trihydroxychalcone, (-)-crotepoxide, demethoxymatteucinol, lawinal, and b...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701194310
更新日期:2007-09-01 00:00:00
abstract::A new cytisine-type alkaloid, along with five known alkaloids was obtained from the seeds of Sophora alopecuroides. Their structures were determined to be (-)-N-(2'-hydroxy-3',5'-di-tert-butyl-toluene)-cytisine (1), (-)-lupanine (2), (+)-matrine (3), (+)-sophoramine (4), (+)-lehmannine (5) and (-)-sophocarpine (6). Th...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1824226
更新日期:2020-09-23 00:00:00
abstract::Ocimum is a genus of aromatic herbs, undershurbs or shrubs distributed in the tropical and warm temperate regions of the world. Larvicidal activity of essential oils and different extracts of O. sanctum, O. basilicum and O. gratissimum were compared on laboratory reared and field collected larvae of Culex quinquefasci...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.551755
更新日期:2011-12-01 00:00:00
abstract::Santolina insularis is a Sardinian endemism that is widely used in traditional medicine. The essential oil was obtained with a yield of 2.7% and is mainly characterized by β-phellandrene (22.6%), myrcene (11.4%) and artemisia ketone (7.6%). The oil significantly reduced NO production without affecting macrophages viab...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1774764
更新日期:2020-06-04 00:00:00
abstract::The chemical composition of the essential oil (EO) obtained from the aerial parts of Rydingia michauxii (Briq.) Scheen & V.A. Albert was analysed by gas chromatography and gas chromatography/mass spectrometry (GC/MS). Eighty components were identified in the oil with caryophyllene oxide (20.1%), trans-verbenol (10.2%)...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1343321
更新日期:2018-01-01 00:00:00
abstract::The proposed work, aims to provide a "green" and cutting-edge technique for the mordanting and dyeing of polyester fabric with natural henna dye using the advanced technology of micro waves. For providing a complete "green" and ecofriendly dyeing process, lemon was used as a natural bio mordant with micro waves and re...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1619721
更新日期:2021-01-01 00:00:00
abstract::Immuno-therapies are gaining more importance to treat certain forms of cancer. The goal of therapies is to enhance person's own IgG, IgA, IgM, IgD, IgE and macrophages to combat with neoplastic cells hence the effectiveness of the immune system. Since, early civilization mushrooms are considered as potent food as well...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1466129
更新日期:2019-09-01 00:00:00
abstract::Euphorbia hirta (L.) plant is traditionally used in Malaysia for the treatment of gastrointestinal, bronchial and respiratory ailments caused by nosocomial infectious agents. Bioactivity-guided fractionation of the methanol extract of the aerial parts of E. hirta and analysis using high-performance liquid chromatograp...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.999242
更新日期:2015-01-01 00:00:00
abstract::A new monoterpenoid indole alkaloid, 10-methoxyakuammidine (1), together with four known alkaloids (2-5), were isolated from the stems and leaves of Ochrosia elliptica. The structure of 1 was elucidated by extensive spectroscopic methods and the known compounds were identified by comparisons with data reported in the ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1277349
更新日期:2017-07-01 00:00:00
abstract::The ethanol extract of the Ficus carica L. leaves was tested to show strong nematicidal activity against pine wood nematode (PWN), Bursaphelenchus xylophilus, causing 90.93% corrected mortality within 72 h at 1.0 mg/mL. From the ethyl acetate soluble fraction of the F. carica L. leaves extract, the main nematicidal co...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1094804
更新日期:2016-09-01 00:00:00
abstract::A new alkaloid, namely laccarin A (1), along with four known alkaloids, laccarin (2), adenosine (3), indole-3-carboxaldehyde (4) and nicotinamide (5), was isolated from the fungus Lactarius subplinthogalus. The structure of laccarin A (1) was established mainly by spectroscopic methods. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410310001608073
更新日期:2004-04-01 00:00:00
abstract::Meliquercifolins A (1), and B (2), two new coumarins are bearing an acetophenone derivative were isolated from the leaves of Melicope quercifolia along with three known compounds, melicodenines E (3), F (4) and I (5). Structures of two new compounds were identified based on spectroscopic analyses (UV, HR-ESI-MS, 1 D a...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1644634
更新日期:2019-07-22 00:00:00
abstract::The Aedes aegypti mosquito is one of the major vectors of arboviruses. These diseases have re-emerged and the insecticides used nowadays are toxic to mammals and environment and have only been effective in the short-term. In this context, natural products are an alternative. The genus Piper has many active compounds a...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1374265
更新日期:2018-11-01 00:00:00
abstract::A new cholestane-type steroidal glycoside, solamyriaside A (1), was isolated from the fruits of Solanum myriacanthum Dunal (Solanaceae), along with two known steroidal glycosides, namely, solaviaside A (2) and aculeatiside A (3), and three known steroidal alkaloid glycosides, namely, solamargine (4), khasianine (5) an...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1781117
更新日期:2020-06-19 00:00:00
abstract::The objective of this work was to produce and characterise nanoemulsions containing tucumã extract and to evaluate the performance of the nanostructure and the free compound regarding antitumor activity, cytotoxicity, and oxidative metabolism in NB4/APL cells. The nanoemulsions showed adequate physicochemical characte...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1862830
更新日期:2020-12-24 00:00:00
abstract::This review covers the literature published since the report of the first compound to December 2006, for marine natural 2,11-cyclized cembranoids isolated from Caribbean sources, with 30 citations, most of them from 2000 to 2006, referring to compounds isolated from the Caribbean gorgonian octocorals Briareum asbestin...
journal_title:Natural product research
pub_type: 杂志文章,评审
doi:10.1080/14786410701760797
更新日期:2009-01-01 00:00:00
abstract::This work reports the phytochemical profile and insecticidal properties of Perovskia artemisioides Boiss essential oil (PAEO) collected in Baluchestan, Iran. Totally, twenty-six substances were identified with 1,8-cineole (25.81%), geranyl acetate (13.00%) and linalool (10.21%) as dominant chemical metabolites by GC-M...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1803311
更新日期:2020-08-26 00:00:00
abstract::The aim of this work was to provide a characterisation of volatile constituents from different commercial batches of henna (Lawsonia inermis) leaves of different geographic origin. Headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC-MS) was used for the purpose. A tota...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1055491
更新日期:2016-01-01 00:00:00
abstract::Inula graveolens (L.) Desf. is an annual aromatic herb which has various uses on alternative medicine in many region of the world. In this study, antioxidant activities of ethanol and water extracts of the plant leaves were determined by in vitro DPPH method and phenolic composition of the plant sample was determined ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1350673
更新日期:2018-06-01 00:00:00
abstract::Three new neolignan derivatives (1-3), together with three known isolariciresinol derivatives (4-6) were isolated from Selaginella picta. Their structures were elucidated by spectroscopic methods (1D/2D NMR, HRESIMS and CD). All isolated compounds were assayed on the neuroprotective activity against the injury of HT-2...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1560284
更新日期:2020-05-01 00:00:00
abstract::Phorbol esters (PEs) are diterpenes present in Jatropha curcas L. seeds and have a myriad of biological activities. Since PEs are toxic, they are considered to be futile in Jatropha-based biodiesel production chain. In the present study, the extracted PEs from Jatropha oil were used as a starting material to synthesis...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.716057
更新日期:2013-01-01 00:00:00
abstract::Six known metabolites, two new isocoumarins 4 and 8, and one new highly substituted benzoic acid derivative 9 were isolated from the ethyl acetate culture extract of a fungal endophyte, Scytalidium sp. In addition, another new benzoic acid 10 with an unusual 1,2-dicarbonyl side chain was indirectly identified from its...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410310001620637
更新日期:2004-06-01 00:00:00
abstract::Propolis is a honeybee product that has been used since ancient times because of its therapeutic effects. It can be used in the development of alternative therapies for the treatment of many diseases, and because propolis shows antibacterial action, this work was carried out in order to investigate a possible synergis...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786411003754355
更新日期:2012-01-01 00:00:00
abstract::The chemical composition of the volatile organic compounds (VOCs) released from the leaves and flowers of Artemisia fragrans Willd. (Asteraceae) was investigated using headspace solid-phase microextraction (HS-SPME) coupled to gas chromatography (GC) and/or GS/mass spectrometry (GC/MS). The efficiency and reliability ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410903108951
更新日期:2010-08-01 00:00:00
abstract::In this study, 12 compounds, which include a new flavanone 5-methoxy mundulin, were isolated from the leaves, stem bark and twigs of Mundulea sericea (Willd.) A. Chev. (Fabaceae; Papilionoideae). The structures of the compounds were identified based on spectral data analyses. The constituents of M. sericea also showed...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.616504
更新日期:2012-01-01 00:00:00
abstract::Three new methylated flavonol glucosides: 3-methoxy-7-O-β-(6″-galloylgluco-pyranoside) quercetin (1), 3,4'-dimethoxy-7-O-β-(6″-galloyl-glucopyranoside) quercetin (2) and 3-methoxy-7-O-β-(6″-galloylgluco-pyranoside) kaempferol (3), in addition to six known flavonols, were isolated from the ethyl acetate extract of Fuma...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.778848
更新日期:2013-01-01 00:00:00
abstract::The antibacterial activity of essential oil and methanolic extract of Teucrium polium was determined against Pseudomonas aeruginosa, Pantoea agglomerans, Brenneria nigrifluens, Rhizobium radiobacter, Rhizobium vitis, Streptomyces scabies, Ralstonia solanacearum, Xanthomonas campestris and Pectobacterium cartovorum by ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.1000320
更新日期:2015-01-01 00:00:00
abstract::A new isopimarane-type diterpenoid, crolaevinoid A, along with four known analogues was isolated from the twigs and leaves of Croton laevigatus. The structures of the isolated compounds were established on the basis of NMR and MS spectroscopic analyses. The isolated compounds were examined the antibacterial activities...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1596096
更新日期:2020-10-01 00:00:00
abstract::Phenolics were extracted from powdered pomegranate peel using water, methanol, acetone and ethyl acetate (EtOAc), respectively. The antiliperoxidant activity of the extracts on lard was studied by peroxide value method. All the extracts showed enhanced inhibitory effect on lard peroxidation with the increase of phenol...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410601130422
更新日期:2007-03-01 00:00:00