Abstract:
:This review covers the literature published since the report of the first compound to December 2006, for marine natural 2,11-cyclized cembranoids isolated from Caribbean sources, with 30 citations, most of them from 2000 to 2006, referring to compounds isolated from the Caribbean gorgonian octocorals Briareum asbestinum, Briareum polyanthes, and Erithropodiun caribaeorum. The emphasis is on all of these natural compounds isolated to date, with an overview of their biogenetic pathway and relevant biological activity.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Cóbar OMdoi
10.1080/14786410701760797subject
Has Abstractpub_date
2009-01-01 00:00:00pages
26-43issue
1eissn
1478-6419issn
1478-6427pii
907732536journal_volume
23pub_type
杂志文章,评审abstract::Fungi are important organisms related to the production of antibiotics, many of which are commercially available and used in the clinic to treat infections. Infectious diseases represent a leading cause of death worldwide, being a severe threat to public health, especially with the rise of multi-resistant microorganis...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.738202
更新日期:2013-01-01 00:00:00
abstract::Timosaponin AIII (TAIII) exhibits extensive pharmacological activities and has been reported as a potent antitumour agent for various human cancers. In the present study, a potential industrial process for producing TAIII that involves biotransformation directly in the crude extract liquid of rhizoma anemarrhenae (RA)...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1169416
更新日期:2016-10-01 00:00:00
abstract::Hechtia glomerata, a Mexican medicinal plant employed against bacterial infections and as food, is taxonomically related to the genus Tillandsia which has anticancer activity. Organic and aqueous extracts of H. glomerata leaves were prepared and tested for cytotoxic and antibacterial activity. UPLC-QTOF-MS analysis de...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1793148
更新日期:2020-07-16 00:00:00
abstract::Loliolide content was determined in 13 marine algae including red, brown and green algae collected from the Black Sea, the Dardanelles and the Aegean Sea. Identification and quantification were performed by gas chromatography-mass spectrometry. The loliolide content in green alga is 1.76 microg g(-1), ranges from 0.14...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802076069
更新日期:2009-01-01 00:00:00
abstract::Neuroprotection under conditions of oxygen stress of two C21 steroidal glycosides, cynsaccatol Q (1) and saccatol K (2), isolated from Cynanchum auriculatum Royle ex Wight, and their potential mechanisms were studied using the model of H2O2-induced damage on PC12 cells in this paper. Experiments showed that compounds ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1636241
更新日期:2019-07-02 00:00:00
abstract::A new denudatine-type C20-diterpenoid alkaloid, designated as sinchianine (1), together with eight known diterpenoid alkaloids, 12-acetyl-12-epi-napelline (2), 12-epi-napelline (3), neoline (4), talatisamine (5), 14-O-acetylsenbusine A (6) and benzoylaconine (7), songorine (8) and aconitine (9), were isolated from the...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1410814
更新日期:2018-10-01 00:00:00
abstract::This study evaluates the presence, location and production source of tetrodotoxin (TTX) in two species of pufferfish, Diodon histrix and Arothron hispidus, common to Hawaiian waters. Organs from each fish were analysed for TTX and used to isolate bacteria for evaluation of possible TTX production. Comparative analyses...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410903003780
更新日期:2009-01-01 00:00:00
abstract::This study investigated the pharmacokinetics of hesperidin (HP), ferulic acid (FA) and p-coumaric acid (CA) in rat plasma after oral administration of Portulaca oleracea L. extract (POE). The plasma concentrations were determined by HPLC with vitexin-2″-O-rhamnoside (VR) as internal standard. The calibration curves we...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.648193
更新日期:2012-01-01 00:00:00
abstract::A new dehydrodigallic acid derivative (1), along with 19 known compounds, including 6 phenolic derivatives, 2 steroids and 11 triterpenoids were isolated from the ethanol extract of the root of Geum urbanum. Herein, there is the first report of steroid and triterpene in Geum urbanum. The purified metabolites were char...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1425844
更新日期:2018-11-01 00:00:00
abstract::The essential oil of Lippia microphylla (LM-OE) presents several pharmacological activities. This work evaluates the tocolytic effect of LM-OE on rats. LM-OE inhibited phasic contractions and relaxed tonic contractions on rat uterus. Considering that nitric oxide (NO) pathway regulates uterine contraction, LM-OE poten...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1614578
更新日期:2019-06-05 00:00:00
abstract::Endophytic fungi represent ubiquitous microbial organisms able to live in the tissues of different plants around the world and represent a prolific source of bioactive metabolites. In the present study, the endophytic fungus Aspergillus calidoustus was isolated from the medicinal plant Acanthospermum australe (Asterac...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1022777
更新日期:2016-01-01 00:00:00
abstract::Two new steroidal alkaloids, salonine-A [(20S)-20-(N,N-dimethylamino)-3beta-(tigloylamino)-5alpha-pregn-14-en-2beta,4beta-diol] (1), and salonine-B [(20S)-20-(N,N-dimethylamino)-3beta-methoxy-pregn-5,16-diene] (2), were isolated from the MeOH extract of Sarcococca saligna, along with a known base, alkaloid-C (3). Thei...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/1057563021000051086
更新日期:2003-08-01 00:00:00
abstract::A new triterpenic glucoside, lup-1,5,20(29)-trien-3-O-beta-D-glucopyranoside (4), along with three known phytoconstituents: n-octacosane, friedelin and beta-amyrin, has been isolated from the leaves of Clerodendrum inerme (L.) Gaertn. (Verbenaceae). Structure elucidation was carried out on the basis of chemical and ph...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410902975566
更新日期:2010-01-01 00:00:00
abstract::Pigeon Pea is a well-received traditional nutritious and medicinal plant in India since ancient times. The plant is identified for its impressive pharmacological activities like antimicrobial, anti-inflammatory, antitubercular, antioxidant, neuroprotective, antihypertensive, antihyperglycemic and anticancer properties...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1849197
更新日期:2020-11-23 00:00:00
abstract::Natural products represent a rich source of bioactive compounds that have been historically used to obtain substances with great medicinal potential. The skin of anuran amphibians is a rich source of compounds with a wide range of biological activity. Alzheimer's disease (AD) is a complex disease associated with all k...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1591396
更新日期:2019-03-31 00:00:00
abstract::Two new lupene-type triterpenoids, 3β,6β-dihydroxylup-20(29)-en-28-oic acid β-glucopyranosyl ester (1) and 2α-acetoxyl-3β,6β-dihydroxylup-20(29)-en-28-oic acid β-glucopyranosyl ester (2), along with 18 known compounds, were isolated from Liquidambar formosana. The structures were elucidated on the basis of spectroscop...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.539569
更新日期:2012-01-01 00:00:00
abstract::Colletia paradoxa (Spreng.) Esc. (Rhamnaceae, Colletieae) is a medicinal plant, threatened with extinction in Brazil, presenting great morphological variability. Our objective is to investigate the phytochemical components, antioxidant capacity and antimycobacterial activity of different morphotypes of C. paradoxa in ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1598987
更新日期:2019-04-16 00:00:00
abstract::A new malyngamide (1) was isolated along with seven known compounds (2-8) from the marine cyanobacterium Moorea producens collected in Hawaii. Compound 1 represented the first reported malyngamide with a hydroxy moiety at C-7 of the characteristic fatty acid portion of the compound. Compound 1 showed cytotoxicity agai...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1338282
更新日期:2018-01-01 00:00:00
abstract::N-methylasimilobine (1), a new-found strong acetylcholinesterase (AChE) inhibitor, along with two weakly active aporphine alkaloids, nuciferine (2) and nornuciferine (3) were separated from Nelumbo nucifera. N-methylasimilobine (1) inhibited 50% of AChE activity at the concentrations of 1.5 ± 0.2 µg mL(-1) when the st...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.487188
更新日期:2012-01-01 00:00:00
abstract::The essential oil of the 'resurrection plant' Myrothamnus moschatus (Baillon) Niedenzu endemic to Madagascar, where it is used in traditional medicine, was investigated for the first time for some biological activities. GC-FID and GC-MS analyses revealed trans-pinocarveol (35.6%), pinocarvone (20.0%), β-selinene (8.5%...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.665916
更新日期:2012-01-01 00:00:00
abstract::This paper aims to investigate, for the first time, physicochemical characteristics and antioxidant capacity of Psidium myrtoides ripe and unripe fruit. In addition, essential oil was extracted from fresh leaves (PM-EO) collected in dry and rainy seasons to investigate the influence of seasonality and, after that, to ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1844689
更新日期:2020-11-09 00:00:00
abstract::From the seed and leaf extracts of Eryngium species, two new compounds were isolated, along with an aliphatic ketone and several known terpenoids reported from a member of Umbelliferae for the first time. Their structures were elucidated by chemical methods and spectroscopic analysis. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701768303
更新日期:2010-03-01 00:00:00
abstract::Nine compounds were isolated from Nocardia sp. YIM 64630, and their structures were elucidated as 5'-O-acetyl-2'-deoxyuridine (1), 22E,24R-5α,6α-epoxyergosta-8(14),22-diene-3β,7α-diol (2), 22E,24R-5α,6α-epoxyergosta-8,22-diene-3β,7α-diol (3), 22E,24R-ergosta-7,22-diene-3β,5α,6β-triol (4), 5α,8α-epidioxyergosta-6,22-di...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.964713
更新日期:2015-01-01 00:00:00
abstract::A new oleanolic-type triterpene glycoside, (3β,21β)-21-[(β-d-glucopyranosyl-(1→2)-β-d-glucopyranosyl)oxy]-3-hydroxyolean-12-en-28-oic acid (1), together with five analogues, oleanazuroside 1 (2), oleanazuroside 2 (3), 24-hydroxytormentic acid ester glucoside (4), 24-epi-pinfaensin (5), and oleanolic acid 3-O-α-l-arabi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1258557
更新日期:2017-04-01 00:00:00
abstract::ABTRACT This study aims to design and synthesize a series of N-Acyl-N-(m-fluoro- benzyl)-6- amino-coumarins through the principle of active substructure stitching, which are based on the core structure of N-(m-fluoro-benzyl)-6-amino-coumarin. The structures of target compounds e1-e25 have been characterized by 1H NMR,...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1806268
更新日期:2020-08-13 00:00:00
abstract::Ocimum is a genus of aromatic herbs, undershurbs or shrubs distributed in the tropical and warm temperate regions of the world. Larvicidal activity of essential oils and different extracts of O. sanctum, O. basilicum and O. gratissimum were compared on laboratory reared and field collected larvae of Culex quinquefasci...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.551755
更新日期:2011-12-01 00:00:00
abstract::In this study, the anti-tumour-promoting and thermal-induced protein denaturation inhibitory activities of β-sitosterol (1) and lupeol (2), isolated from Diospyros lotus L., were explored. Compound 1 showed a marked concentration-dependent inhibition against 12-O-tetradecanoylphorbol-13-acetate (20 ng/32 pmol)-induced...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1046381
更新日期:2016-01-01 00:00:00
abstract::The use of a matrix solid-phase dispersion (MSPD) process to extract polyphenols from hawthorn (Crataegus oxyacantha L.) a deciduous shrub with an expected rich phytochemical profile, has been evaluated. MSPD extracts of fruits and leaves have an outstanding content of polyphenols, although the particular phenolic pro...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1326040
更新日期:2018-05-01 00:00:00
abstract::From the fruit of Pandanus tectorius Parkinson ex Du Roi, one new dihydrofurocoumarin, named pandanusin A (1) and 15 known compounds, including one furanocoumarin (2), two coumarins (3, 4), four lignans (5-8), one neolignan (9), two flavonoids (10, 11), three phenolics (12-14), one monoglyceride (15) and one monosacch...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1188095
更新日期:2016-11-01 00:00:00
abstract::A new compound, jolynamine (1), was isolated from the marine brown alga Jolyna laminarioides collected from the coast of Karachi, Pakistan. In addition, four known compounds, namely saringosterol (2), loliolide (3), methyl-4-hydroxybenzoate (4) and propyl-4-hydroxybenzoate (5), were isolated for the first time from th...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.509722
更新日期:2011-05-01 00:00:00