Porritoxins, metabolites of Alternaria porri, as anti-tumor-promoting active compounds.

abstract：:Methanolic extracts of 18 Thai plants from Doi Tung, the north of Thailand, were examined for brine shrimp lethality and antioxidative activity using 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. In brine shrimp lethality, the highly toxic plant extracts were Mitrephora wangii (LC(50) 14.8 µg mL(-1)) and Hydrocotyle jav...

journal_title：Natural product research

authors： Tanamatayarat P,Sotanaphun U,Poobrasert O

更新日期：2012-01-01 00:00:00

abstract：:One new sesqui-neolignan compound, namely, sesqui-illisimonan A (1), one new neolignan, illisimonan A (2), and one new phenylpropanoid compound, illisimoid A (3) were isolated from the fruits of Illicium simonsii Maxim. The structures and absolute configurations of these compounds were determined by extensive spectros...

journal_title：Natural product research

authors： Zhuang PY,Chen MH,Wang YN,Wang XX,Feng YJ,Zhang DY

更新日期：2018-10-01 00:00:00

abstract：:A total of 205 bluefin and yellowfin tuna samples were examined for mercury detection in order to verify possible differences and have a detailed risk assessment of the two tuna species. The results showed significant higher mercury concentration in muscle tissue of bluefin tuna respect yellowfin tuna (p < 0.001) with...

journal_title：Natural product research

authors： Cammilleri G,Vazzana M,Arizza V,Giunta F,Vella A,Lo Dico G,Giaccone V,Giofrè SV,Giangrosso G,Cicero N,Ferrantelli V

更新日期：2018-02-01 00:00:00

abstract：:Two diketopiperazines were isolated from a culture of the marine-derived actinomycete Streptomyces sp. ZZ446. Their structures were elucidated as maculosin (1) and maculosin-O-α-L-rhamnopyranoside (2) based on their NMR and HRESIMS data, specific rotation, and chemical degradation. Maculosin-O-α-L-rhamnopyranoside (2)...

journal_title：Natural product research

authors： Chen S,Zhang D,Chen M,Zhang Z,Lian XY

更新日期：2020-04-01 00:00:00

abstract：:Investigation on the leaves of Melicope bonwickii (F.Muell.) T.Hartley (Rutaceae) afforded a new 7-(2'-hydroxy-3'-chloroprenyloxy)-4-methoxyfuroquinoline (1) together with the known 7-(2',3'-epoxyprenyloxy)-4-methoxyfuroquinoline (2), evellerine (3) kokusaginine (4) and an amide aurantiamide acetate (5). Compounds 1 a...

journal_title：Natural product research

authors： Komala I,Rahmani M,Sukari MA,Mohd Ismail HB,Cheng Lian GE,Rahmat A

更新日期：2006-04-01 00:00:00

abstract：:Inula graveolens (L.) Desf. is an annual aromatic herb which has various uses on alternative medicine in many region of the world. In this study, antioxidant activities of ethanol and water extracts of the plant leaves were determined by in vitro DPPH method and phenolic composition of the plant sample was determined ...

journal_title：Natural product research

authors： Silinsin M,Bursal E

更新日期：2018-06-01 00:00:00

abstract：:Chemical diversity is vital to antitubercular drug discovery as it ensures a novel bioactivity profile. Marine sponges have so far provided more than 1000 new bioactive molecules. Ethyl acetate extract of the marine sponge Dendrilla nigra on bioactivity-guided screening yielded three new compounds denigrins A-C, with ...

journal_title：Natural product research

authors： Murali Krishna Kumar M,Devilal Naik J,Satyavathi K,Ramana H,Raghuveer Varma P,Purna Nagasree K,Smitha D,Venkata Rao D

更新日期：2014-01-01 00:00:00

abstract：:A new xanthone named cratoxylumxanthone A (1), together with five known compounds: dulcisxanthone B (2), alpha-mangostin (3), beta-mangostin (4), 2-geranyl-1,3,7-trihydroxy-4-(3-methylbut-2-enyl)xanthone (5) and tectochrystin (6), was isolated from Cratoxylum cochinchinense stems. The structure of new compound was cha...

journal_title：Natural product research

authors： Phuwapraisirisan P,Udomchotphruet S,Surapinit S,Tip-Pyang S

更新日期：2006-12-01 00:00:00

abstract：:Ten compounds (1-10) were purified from the extract of lichens C. faveomaculata, and among these one new triterpenoid, cryptothecin A (1) was characterized through mass spectrometric and 2D NMR spectroscopic analyses. Some of the isolated compounds were assessed for their antimicrobial (1, 6, and 8) and cytotoxic acti...

journal_title：Natural product research

authors： Ngoc Tuan N,Kuo PC,Trung Hieu T,Tuong Vi LN,Tong Hung Q,Dunge LT,Duy Trinh N,Quang Trung N,Cuu Khoa N,Viet Hai H,Thang TD

更新日期：2019-08-02 00:00:00

abstract：:The mechanism of inhibition of jack bean and Bacillus pasteurii ureases was investigated by triacontanyl palmitate (1) which is a long-chain fatty ester and has been isolated from Symplocos racemosa Roxb. Lineweaver-Burk, Dixon plots, and their secondary replots showed that 1 is a non-competitive inhibitor of these en...

journal_title：Natural product research

authors： Lodhi MA,Abbasi MA,Choudhary MI,Ahmad VU

更新日期：2007-07-10 00:00:00

abstract：:Polyphyllin Ι is a steroidal saponin isolated from the rhizoma of Paris polyphylla. In the present study, we aimed to investigate the anticancer effects of polyphyllin Ι in colorectal cancer and to elucidate the potential underlying molecular mechanisms. Using, CCK8 assay, flow cytometry, laser confocal microscope ana...

journal_title：Natural product research

authors： Yu S,Wang L,Cao Z,Gong D,Liang Q,Chen H,Fu H,Wang W,Tang X,Xie Z,He Y,Peng C,Li Y

更新日期：2018-06-01 00:00:00

abstract：:Two new monoterpene glucosides: xanmonoter A (1) and xanmonoter B (2) were isolated from Xanthium strumarium. Their structures were elucidated on the basis of 1D and 2D NMR, MS and CD analysis. Compounds 1 and 2 were tested for their anti-inflammatory activity with IC50 values of 17.4, 22.1 μM, respectively. ...

journal_title：Natural product research

authors： Jiang H,Xing X,Yan M,Guo X,Yang L,Yang L

更新日期：2019-12-01 00:00:00

abstract：:The antiradical activity of the freshwater bryozoan Hyalinella punctata water extracts (two samples, seasonal collection) was evaluated by using electron paramagnetic resonance spectroscopy against hydroxyl (√OH), superoxide anion (√O2(- )), methoxy (√CH2OH), carbon-dioxide anion (√CO2(- )), nitric-oxide (√NO) and 2,2...

journal_title：Natural product research

authors： Pejin B,Savic AG,Hegedis A,Karaman I,Horvatovic M,Mojovic M

更新日期：2014-01-01 00:00:00

abstract：:Two alkaloids of the furoquinoline-type were isolated from Ammi majus L.; a new one and was identified as 4-hydro-7-hydroxy-8-methoxyfuroquinoline (1), and the other was isolated for the second time from nature and was identified as 4-hydro-7-hydroxy-8-prenyloxyfuroquinoline (2). The structures of the isolated compoun...

journal_title：Natural product research

authors： Mohammed MM,El-Sharkawy ER

更新日期：2017-03-01 00:00:00

abstract：:Two new sphingofungins G (1) and H (2) with a five-membered lactone ring were identified from the solid-state fermentation of Aspergillus penicilliodes Speg., a dominant microorganism isolated previously from the post-fermentation of ripe Pu-er tea, together with six known metabolites. Their structures were elucidated...

journal_title：Natural product research

authors： Zhang H,Zhu HT,Wang D,Yang CR,Zhang YJ

更新日期：2019-05-01 00:00:00

abstract：:A total of 25 compounds including terpenoids, flavonoids, biflavonoids and ginkgolic acids were identified and quantified with a reliable, simple, and simultaneous method from Ginkgo leaves, seed coats and embryoids with different tree ages (approximately identified as 25, 500, 1000 and 2000 years). Leaves had the hig...

journal_title：Natural product research

authors： Chen X,Zhong W,Shu C,Yang H,Li E

更新日期：2020-07-01 00:00:00

abstract：:Phytochemical investigation of Strychnos nitida has led to the isolation of three new racemic pyridocarbazole alkaloids, (±)-stritidas A-C (1-3) and three known monoterpenoid indole alkaloids (4-6). Compounds 2 and 3 represent the first examples of pyridocarbazole alkaloids featuring an N-2-hydroxyethyl moiety. Their ...

journal_title：Natural product research

authors： Li W,Tang GH,Chen L,Tang YQ,Xu YK,Liu B,Yin S

更新日期：2018-07-01 00:00:00

abstract：:Natural estrogens have demonstrated a wide variety of biological activities, which makes them a good candidate for the treatment of diabetes. In vitro, this study evidenced that isoflavones enhanced insulin secretion and inhibited α-amylase activity. In vivo, the findings indicated that soy isoflavones stimulated insu...

journal_title：Natural product research

authors： Hamden K,Jaouadi B,Carreau S,Aouidet A,Elfeki A

更新日期：2011-02-01 00:00:00

abstract：:In the context of our previous communication on phytochemical studies of the ethanolic extract of flowers of Alstonia scholaris of Pakistan origin, these have resulted in the isolation of two new triterpenoids. One is of the oleanane type, alstoprenyol, 3-β-hydroxy-28-β-acetoxy-5-olea triterpene (1), the other is of u...

journal_title：Natural product research

authors： Sultana N,Saify ZS,Saleem M,Kamal M

更新日期：2013-01-01 00:00:00

abstract：:Lavandin (Lavandula × intermedia Emeric ex Loiseleur) essential oils (EOs), from Abrial, Super and Grosso cultivars, cultivated and extracted in the South East of Spain, were analysed by using GC/MS to determine their composition, in both relative (peak area) and absolute (using standard curves) concentrations. Linalo...

journal_title：Natural product research

authors： Carrasco A,Martinez-Gutierrez R,Tomas V,Tudela J

更新日期：2016-01-01 00:00:00

abstract：:Antibacterial activities of prenylated xanthones from Garcinia mangostana and their synthetic analogues were investigated, and their structure-activity relationships have been studied. γ-Mangostin has shown antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA), methicillin sensitive Staphyl...

journal_title：Natural product research

authors： Dharmaratne HR,Sakagami Y,Piyasena KG,Thevanesam V

更新日期：2013-01-01 00:00:00

abstract：:Herein we report the regioselective synthesis of podophyllotoxin-Glycosyl triazole hybrids catalysed by Ag(I)-N-heterocyclic carbene (Ag(I)-NHC) in a short reaction time (∼30 min) at ambient conditions. In principle, it is the first report of Click alkyne-azide cycloaddition catalysed by Ag(I)-NHC catalyst and moreove...

journal_title：Natural product research

authors： Nerella S,Kankala S,Gavaji B

更新日期：2021-01-01 00:00:00

abstract：:A sesquiterpenoid quinone, epi-ilimaquinone (1), and two sesquiterpene amino quinones, smenospongine (2) and glycinylilimaquinone (3), were isolated from the Fijian marine sponge Hippospongia sp. The structures of these compounds were determined by spectroscopic analysis. Compounds 1 and 3 were reported for the first ...

journal_title：Natural product research

authors： Kumar R,Subramani R,Aalbersberg W

更新日期：2013-01-01 00:00:00

abstract：:A new cytisine-type alkaloid, along with five known alkaloids was obtained from the seeds of Sophora alopecuroides. Their structures were determined to be (-)-N-(2'-hydroxy-3',5'-di-tert-butyl-toluene)-cytisine (1), (-)-lupanine (2), (+)-matrine (3), (+)-sophoramine (4), (+)-lehmannine (5) and (-)-sophocarpine (6). Th...

journal_title：Natural product research

authors： Rong ZJ,Gao XX,Hu GS,Yan T,Jia JM,Wang AH

更新日期：2020-09-23 00:00:00

abstract：:A flavanone has been isolated first time from the stem of Bauhinia variegata, and its structure was identified by colour reactions and spectral analysis. In a search for novel anticancer compounds from medicinal plants, the isolated flavanone was tested for cytotoxic activity against 57 human tumour lines, representin...

journal_title：Natural product research

authors： Rajkapoor B,Murugesh N,Rama Krishna D

更新日期：2009-01-01 00:00:00

abstract：:Tannic acid, a rich of natural and process-derived phenolic compound, has been shown to be an effective antagonist against viruses and bacteria. In this study, we determined the antimicrobial activity and mechanisms of tannic acid against Staphylococcus aureus with emphasis on inhibiting effect on biofilm formation. B...

journal_title：Natural product research

authors： Dong G,Liu H,Yu X,Zhang X,Lu H,Zhou T,Cao J

更新日期：2018-09-01 00:00:00

abstract：:The lipid peroxidation inhibitory activities of four hydroxyxanthones, isolated from the whole plant Swertia decussata, were evaluated for the first time. The most promising antioxidant among the xanthones, 1,7,8-trihydroxy-3-methoxyxanthone (swertianine, 4) was also tested for its scavenging potential against DPPH an...

journal_title：Natural product research

authors： Patro BS,Chintalwar GJ,Chattopadhyay S

更新日期：2005-06-01 00:00:00

abstract：:A continuous phytochemical study on the seeds of Senna obtusifolia (Syn.: Cassia obtusifolia) led to the isolation of a new anthraquinone analogue, obtusifolin-2-O-β-D-(6'-O-α,β-unsaturated butyryl)-glucopyranoside (1) and a new eurotinone analogue, epi-9-dehydroxyeurotinone-β-D-glucopyranoside (2). Their structures w...

journal_title：Natural product research

authors： Pang X,Wang LM,Zhang YC,Kang LP,Yu HS,Fan GW,Han LF

更新日期：2019-12-01 00:00:00

abstract：:A new polycyclic polyprenylated acylphloroglucinol (1), nujiangefolin D, together with five known analogues (2-6), were isolated from the fruits of Garcinia nujiangensis. Compound 1 was screened by the LC-MS and LC-PDA. The structure of 1 was elucidated on the basis of extensive spectroscopic techniques including 1 D ...

journal_title：Natural product research

authors： Tang Z,Lu L,Zhou X,Shen J,Song W,Tang Y,Xia Z

更新日期：2020-09-01 00:00:00

abstract：:Phytochemical investigation on the stem bark of Shorea maxwelliana yielded five oligostilbenoids identified as α-viniferin (1), maximol A (2), vaticanol A (3), suffruticosol A (4) and vaticanol G (5). Chemotaxonomy of isolated compounds was discussed briefly. Major compounds were tested for neurotoxic and cytotoxic ac...

journal_title：Natural product research

authors： Zawawi NK,Ahmat N,Mazatulikhma MZ,Shafiq RM,Wahid NH,Sufian AS

更新日期：2013-01-01 00:00:00